PMC Links for Books (Select 5247958) - PMC

Select item 79882791.

The European Medicines Agency review of entrectinib for the treatment of adult or paediatric patients with solid tumours who have a neurotrophic tyrosine receptor kinase gene fusions and adult patients with non-small-cell lung cancer harbouring ROS1 rearrangements

J. Delgado, E. Pean, D. Melchiorri, C. Migali, F. Josephson, H. Enzmann, F. Pignatti

ESMO Open. 2021 Apr; 6(2): 100087. Published online 2021 Mar 16. doi: 10.1016/j.esmoop.2021.100087

PMCID:: PMC7988279

Abstract Article PDF–247K

Select item 78117902.

Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials

Alexander Drilon, Salvatore Siena, Rafal Dziadziuszko, Fabrice Barlesi, Matthew G Krebs, Alice T Shaw, Filippo de Braud, Christian Rolfo, Myung-Ju Ahn, Jürgen Wolf, Takashi Seto, Byoung Chul Cho, Manish R Patel, Chao-Hua Chiu, Thomas John, Koichi Goto, Christos S Karapetis, Hendrick-Tobias Arkenau, Sang-We Kim, Yuichiro Ohe, Yu-Chung Li, Young K Chae, Christine H Chung, Gregory A Otterson, Haruyasu Murakami, Chia-Chi Lin, Daniel S W Tan, Hans Prenen, Todd Riehl, Edna Chow-Maneval, Brian Simmons, Na Cui, Ann Johnson, Susan Eng, Timothy R Wilson, Robert C Doebele

Lancet Oncol. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Lancet Oncol. 2020 Feb; 21(2): 261–270. Published online 2019 Dec 11. doi: 10.1016/S1470-2045(19)30690-4

PMCID:: PMC7811790

Abstract Article PDF–543K

Select item 74616303.

Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials

Robert C Doebele, Alexander Drilon, Luis Paz-Ares, Salvatore Siena, Alice T Shaw, Anna F Farago, Collin M Blakely, Takashi Seto, Byung Chul Cho, Diego Tosi, Benjamin Besse, Sant P Chawla, Lyudmila Bazhenova, John C Krauss, Young Kwang Chae, Minal Barve, Ignacio Garrido-Laguna, Stephen V Liu, Paul Conkling, Thomas John, Marwan Fakih, Darren Sigal, Herbert H Loong, Gary L Buchschacher, Jr, Pilar Garrido, Jorge Nieva, Conor Steuer, Tobias R Overbeck, Daniel W Bowles, Elizabeth Fox, Todd Riehl, Edna Chow-Maneval, Brian Simmons, Na Cui, Ann Johnson, Susan Eng, Timothy R Wilson, George D Demetri

Lancet Oncol. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Lancet Oncol. 2020 Feb; 21(2): 271–282. Published online 2019 Dec 11. doi: 10.1016/S1470-2045(19)30691-6

PMCID:: PMC7461630

Abstract Article PDF–473K

Select item 53805834.

Safety and Antitumor Activity of the Multi-Targeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib (RXDX-101): Combined Results from Two Phase 1 Trials (ALKA-372-001 and STARTRK-1)

Alexander Drilon, Salvatore Siena, Sai-Hong Ignatius Ou, Manish Patel, Myung Ju Ahn, Jeeyun Lee, Todd M. Bauer, Anna F. Farago, Jennifer J. Wheler, Stephen V. Liu, Robert Doebele, Laura Giannetta, Giulio Cerea, Giovanna Marrapese, Michele Schirru, Alessio Amatu, Katia Bencardino, Laura Palmeri, Andrea Sartore-Bianchi, Angelo Vanzulli, Sara Cresta, Silvia Damian, Matteo Duca, Elena Ardini, Gang Li, Jason Christiansen, Karey Kowalski, Ann Johnson, Rupal Patel, David Luo, Edna Chow-Maneval, Zachary Hornby, Pratik S. Multani, Alice T. Shaw, Filippo G. De Braud

Cancer Discov. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Cancer Discov. 2017 Apr; 7(4): 400–409. Published online 2017 Feb 9. doi: 10.1158/2159-8290.CD-16-1237

PMCID:: PMC5380583

Abstract Article PDF–1.1M

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