Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 727649-81-2
Drug Levels and Effects
Summary of Use during Lactation
Although no published data exist on the use of aclidinium during breastfeeding, it produces low maternal serum levels because of rapid hydrolysis to inactive metabolites. The risk to the breastfed infant of maternal aclidinium inhalation is small.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Substance Identification
Substance Name
Aclidinium
CAS Registry Number
727649-81-2
Drug Class
- Breast Feeding
- Anti-Asthmatic Agents
- Parasympatholytics
- Muscarinic Antagonists
- Bronchodilator Agents
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Downregulation of the cough reflex by aclidinium and tiotropium in awake and anesthetized rabbits.[Pulm Pharmacol Ther. 2016]Downregulation of the cough reflex by aclidinium and tiotropium in awake and anesthetized rabbits.Mutolo D, Cinelli E, Iovino L, Pantaleo T, Bongianni F. Pulm Pharmacol Ther. 2016 Jun; 38:1-9. Epub 2016 Apr 11.
- Review Umeclidinium.[Drugs and Lactation Database (...]Review Umeclidinium.. Drugs and Lactation Database (LactMed®). 2006
- Review Aclidinium bromide, a new, long-acting, inhaled muscarinic antagonist: in vitro plasma inactivation and pharmacological activity of its main metabolites.[Eur J Pharm Sci. 2010]Review Aclidinium bromide, a new, long-acting, inhaled muscarinic antagonist: in vitro plasma inactivation and pharmacological activity of its main metabolites.Sentellas S, Ramos I, Albertí J, Salvà M, Antón F, Miralpeix M, Beleta J, Gavaldà A. Eur J Pharm Sci. 2010 Mar 18; 39(5):283-90. Epub 2010 Jan 20.
- Identification of the human enzymes responsible for the enzymatic hydrolysis of aclidinium bromide.[Drug Metab Dispos. 2010]Identification of the human enzymes responsible for the enzymatic hydrolysis of aclidinium bromide.Albertí J, Martinet A, Sentellas S, Salvà M. Drug Metab Dispos. 2010 Jul; 38(7):1202-10. Epub 2010 Mar 23.
- Review The discovery and development of aclidinium bromide for the treatment of chronic obstructive pulmonary disease.[Expert Opin Drug Discov. 2018]Review The discovery and development of aclidinium bromide for the treatment of chronic obstructive pulmonary disease.Malerba M, Radaeli A, Santini G, Morjaria J, Mores N, Mondino C, Macis G, Montuschi P. Expert Opin Drug Discov. 2018 Jun; 13(6):563-577. Epub 2018 Apr 4.
- Aclidinium - Drugs and Lactation Database (LactMed®)Aclidinium - Drugs and Lactation Database (LactMed®)
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