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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 1460293-15-5
Drug Levels and Effects
Summary of Use during Lactation
Information in this record refers to the use of yttrium 90 ibritumomab tiuxetan as a therapeutic agent. No information is available on the use of yttrium 90 ibritumomab tiuxetan during breastfeeding. Because of the long half-life of yttrium 90, the manufacturer and expert opinion recommend not administering the drug in women who wish to continue breastfeeding.[1] If the drug is administered to a nursing mother, breastfeeding should be discontinued. No restrictions on holding the infant after administration of the drug are necessary.[2]
Drug Levels
Yttrium-90 decays by emission of beta particles, with a physical half-life of 64.1 hours and a decay energy of 2.28 MeV.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Goldsmith SJ. Radioimmunotherapy of lymphoma: Bexxar and Zevalin. Semin Nucl Med 2010;40:122-35. [PubMed: 20113680]
- 2.
- Gulec SA, Siegel JA. Posttherapy radiation safety considerations in radiomicrosphere treatment with 90Y-microspheres. J Nucl Med 2007;48:2080-6. [PubMed: 18006608]
Substance Identification
Substance Name
Yttrium 90 Ibritumomab Tiuxetan
CAS Registry Number
1460293-15-5
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Review Indium 111 Ibritumomab Tiuxetan.[Drugs and Lactation Database (...]Review Indium 111 Ibritumomab Tiuxetan.. Drugs and Lactation Database (LactMed®). 2006
- Subsequent chemotherapy regimens are well tolerated after radioimmunotherapy with yttrium-90 ibritumomab tiuxetan for non-Hodgkin's lymphoma.[J Clin Oncol. 2002]Subsequent chemotherapy regimens are well tolerated after radioimmunotherapy with yttrium-90 ibritumomab tiuxetan for non-Hodgkin's lymphoma.Ansell SM, Ristow KM, Habermann TM, Wiseman GA, Witzig TE. J Clin Oncol. 2002 Sep 15; 20(18):3885-90.
- Yttrium-90 ibritumomab tiuxetan-induced complete remission in a patient with classical lymphocyte-rich Hodgkin's Lymphoma.[Onkologie. 2008]Yttrium-90 ibritumomab tiuxetan-induced complete remission in a patient with classical lymphocyte-rich Hodgkin's Lymphoma.Schnell R, Dietlein M, Schomäcker K, Kobe C, Borchmann P, Schicha H, Hallek M, Engert A. Onkologie. 2008 Feb; 31(1-2):49-51. Epub 2008 Jan 22.
- Use of 90Y-ibritumomab tiuxetan in non-Hodgkin's lymphoma.[Semin Oncol. 2005]Use of 90Y-ibritumomab tiuxetan in non-Hodgkin's lymphoma.Marcus R. Semin Oncol. 2005 Feb; 32(1 Suppl 1):S36-43.
- Review Ongoing trials with yttrium 90-labeled ibritumomab tiuxetan in patients with non-Hodgkin's lymphoma.[Clin Lymphoma. 2004]Review Ongoing trials with yttrium 90-labeled ibritumomab tiuxetan in patients with non-Hodgkin's lymphoma.Micallef IN. Clin Lymphoma. 2004 Oct; 5 Suppl 1:S27-32.
- Yttrium 90 Ibritumomab Tiuxetan - Drugs and Lactation Database (LactMed®)Yttrium 90 Ibritumomab Tiuxetan - Drugs and Lactation Database (LactMed®)
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