CASRN: 19393-08-9
Drug Levels and Effects
Summary of Use during Lactation
Information in this record refers to the use of (1-14C)-triolein as a diagnostic agent. Breastfeeding does not need to be suspended after administration of (1-14C)-triolein.[1,2]
Drug Levels
Carbon 14 is a low-energy beta emitter with a physical half-life of about 5730 years. (1-14C)-triolein has an effective half-life of 15 hours. Approximately 14% of the injected radioactivity is excreted into breastmilk.[1]
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Leide-Svegborn S, Ahlgren L, Johansson L, et al. Excretion of radionuclides in human breast milk after nuclear medicine examinations. Biokinetic and dosimetric data and recommendations on breastfeeding interruption. Eur J Nucl Med Mol Imaging. 2016;43:808–21. [PubMed: 26732471]
- 2.
- Mattsson S, Johansson L, Leide Svegborn S, et al. Radiation dose to patients from radiopharmaceuticals: A compendium of current information related to frequently used substances. Annex D. Recommendations on breast-feeding interruptions. Ann ICRP. 2015;44(2) Suppl:319–21. [PubMed: 26069086]
Substance Identification
Substance Name
(1-14C)-Triolein
CAS Registry Number
19393-08-9
Drug Class
Breast Feeding
Lactation
Radiopharmaceuticals
Carbon Radioisotopes
Diagnostic Agents
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Publication Details
Publication History
Last Revision: July 20, 2020.
Copyright
Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Publisher
National Institute of Child Health and Human Development, Bethesda (MD)
NLM Citation
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. (1-14C)-Triolein. [Updated 2020 Jul 20].