Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 38677-81-5
Drug Levels and Effects
Summary of Use during Lactation
Pirbuterol is no longer marketed in the US. Although no published data exist on the use of pirbuterol by mouth or inhaler during lactation, data from the related drug, terbutaline, indicate that very little is expected to be excreted into breastmilk.[1] The authors of several reviews and an expert panel agree that use of inhaled bronchodilators is acceptable during breastfeeding because of the low bioavailability and maternal serum levels after use.[2-5]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
References
- 1.
- Boreus LO, de Chateau P, Lindberg C, et al. Terbutaline in breast milk. Br J Clin Pharmacol. 1982;13:731–2. Letter. [PMC free article: PMC1402089] [PubMed: 7082542]
- 2.
- McDonald CF, Burdon JGW. Asthma in pregnancy and lactation. A position paper for the Thoracic Society of Australia and New Zealand. Med J Aust. 1996;165:485–8. [PubMed: 8937369]
- 3.
- Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001;56:325–8. [PMC free article: PMC1746013] [PubMed: 11254828]
- 4.
- Taddio A, Ito S. Drugs and breast-feeding. In, Koren G, ed. Maternal-fetal toxicology. A clinician's guide. 3rd ed. New York. Marcel Dekker. 2001:177-32.
- 5.
- National Heart, Lung, and Blood, Institute, et al. NAEPP expert panel report. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004:1-57. [PubMed: 15637545]
Substance Identification
Substance Name
Pirbuterol
CAS Registry Number
38677-81-5
Drug Class
Breast Feeding
Milk, Human
Anti-Asthmatic Agents
Bronchodilator Agents
Beta Adrenergic Agonists
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PMCPubMed Central citations
- PubChem SubstanceRelated PubChem Substances
- PubMedLinks to PubMed
- Review Bitolterol.[Drugs and Lactation Database (...]Review Bitolterol.. Drugs and Lactation Database (LactMed®). 2006
- Review Metaproterenol.[Drugs and Lactation Database (...]Review Metaproterenol.. Drugs and Lactation Database (LactMed®). 2006
- Review Albuterol.[Drugs and Lactation Database (...]Review Albuterol.. Drugs and Lactation Database (LactMed®). 2006
- Review Levalbuterol.[Drugs and Lactation Database (...]Review Levalbuterol.. Drugs and Lactation Database (LactMed®). 2006
- Review Formoterol.[Drugs and Lactation Database (...]Review Formoterol.. Drugs and Lactation Database (LactMed®). 2006
- Pirbuterol - Drugs and Lactation Database (LactMed®)Pirbuterol - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...