Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 92129-86-7
Drug Levels and Effects
Summary of Use during Lactation
There is no reason to withhold breastfeeding after tuberculosis skin testing or to avoid skin testing in nursing mothers.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
There is some evidence that breastfed infants can acquire immune responsiveness to tuberculin via breastmilk.[1][2][3] However, other investigators have found no evidence of breastmilk transfer of immunity.[4]
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Martinez-Cairo Cueto S, Alasio-Chavez C, Davila Velasquez JR. [In vitro transfer of immunity against PPD with dialyzable extract of leukocytes from human colostrum]. Rev Alerg. 1992;39:126-32. [PubMed: 1492196]
- 2.
- Schlesinger JJ, Covelli HD. Evidence for transmission of lymphocyte responses to tuberculin by breast-feeding. Lancet. 1977;2:529-32. [PubMed: 95733]
- 3.
- Masters PL. Maternal transmission of skin sensitivity to tuberculin. Lancet. 1982;2:276-7. [PubMed: 6124704]
- 4.
- Keller MA, Rodgriguez AL, Alvarez S et al. Transfer of tuberculin immunity from mother to infant. Pediatr Res.1987;22:277-81. [PubMed: 3658548]
Substance Identification
Substance Name
Tuberculin
CAS Registry Number
92129-86-7
Drug Class
- Breast Feeding
- Antigens
- Purified Protein Derivative
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PubMedLinks to PubMed
- Comparable specificity of 2 commercial tuberculin reagents in persons at low risk for tuberculous infection.[JAMA. 1999]Comparable specificity of 2 commercial tuberculin reagents in persons at low risk for tuberculous infection.Villarino ME, Burman W, Wang YC, Lundergan L, Catanzaro A, Bock N, Jones C, Nolan C. JAMA. 1999 Jan 13; 281(2):169-71.
- Increase in tuberculin skin test converters among health care workers after a change from Tubersol to Aplisol.[Am J Infect Control. 2006]Increase in tuberculin skin test converters among health care workers after a change from Tubersol to Aplisol.Gillenwater KA, Sapp SC, Pearce K, Siberry GK. Am J Infect Control. 2006 Dec; 34(10):651-4.
- Extent and effects of recurrent shortages of purified-protein derivative tuberculin skin test antigen solutions - United States, 2013.[MMWR Morb Mortal Wkly Rep. 2013]Extent and effects of recurrent shortages of purified-protein derivative tuberculin skin test antigen solutions - United States, 2013.Centers for Disease Control and Prevention (CDC). MMWR Morb Mortal Wkly Rep. 2013 Dec 13; 62(49):1014-5.
- Review Purified protein derivatives of tuberculin--past, present, and future.[FEMS Immunol Med Microbiol. 2012]Review Purified protein derivatives of tuberculin--past, present, and future.Yang H, Kruh-Garcia NA, Dobos KM. FEMS Immunol Med Microbiol. 2012 Dec; 66(3):273-80. Epub 2012 Aug 1.
- Review Tuberculin testing in patients with human immunodeficiency virus/acquired immune deficiency syndrome.[AACN Clin Issues. 1996]Review Tuberculin testing in patients with human immunodeficiency virus/acquired immune deficiency syndrome.Jones SG. AACN Clin Issues. 1996 Aug; 7(3):378-89.
- Tuberculin - Drugs and Lactation Database (LactMed®)Tuberculin - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...