Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 513-10-0
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of echothiophate ophthalmic drops during breastfeeding. Because echothiophate is a quaternary ammonium compound, it is not likely to pass into the breastmilk or reach the bloodstream of the infant.[1]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information in nursing mothers was not found as of the revision date. In animals, cholinergic drugs increase oxytocin release, and have variable effects on serum prolactin.[2,3] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
References
- 1.
- Johnson SM, Martínez M, Freedman S. Management of glaucoma in pregnancy and lactation. Surv Ophthalmol. 2001;45:449–54. [PubMed: 11274697]
- 2.
- Clarke G, Fall CH, Lincoln DW, et al. Effects of cholinoceptor antagonists on the suckling-induced and experimentally evoked release of oxytocin. Br J Pharmacol. 1978;63:519–27. [PMC free article: PMC1668097] [PubMed: 566601]
- 3.
- Müller EE, Locatelli V, Cella S, et al. Prolactin-lowering and -releasing drugs: Mechanisms of action and therapeutic applications. Drugs. 1983;25:399–432. [PubMed: 6133737]
Substance Identification
Substance Name
Echothiophate
CAS Registry Number
513-10-0
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PMCPubMed Central citations
- PubChem SubstanceRelated PubChem Substances
- PubMedLinks to PubMed
- Review Sodium Iodide I 131.[Drugs and Lactation Database (...]Review Sodium Iodide I 131.. Drugs and Lactation Database (LactMed®). 2006
- Review Carbachol.[Drugs and Lactation Database (...]Review Carbachol.. Drugs and Lactation Database (LactMed®). 2006
- Review Malathion.[Drugs and Lactation Database (...]Review Malathion.. Drugs and Lactation Database (LactMed®). 2006
- Review Levocarnitine.[Drugs and Lactation Database (...]Review Levocarnitine.. Drugs and Lactation Database (LactMed®). 2006
- Review Acetylcholine.[Drugs and Lactation Database (...]Review Acetylcholine.. Drugs and Lactation Database (LactMed®). 2006
- Echothiophate - Drugs and Lactation Database (LactMed®)Echothiophate - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...