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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 50-35-1
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of thalidomide during breastfeeding. The manufacturer and professional guidelines recommend against the use of thalidomide during breastfeeding [1-3]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- van der Woude CJ, Ardizzone S, Bengtson MB, et al. The second European evidenced-based consensus on reproduction and pregnancy in inflammatory bowel disease. J Crohns Colitis 2015;9:107-24. [PubMed: 25602023]
- 2.
- Sammaritano LR, Bermas BL, Chakravarty EE, et al. 2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases. Arthritis Rheumatol 2020;72:529-56. [PubMed: 32090480]
- 3.
- Torres J, Chaparro M, Julsgaard M, et al. European Crohn's and Colitis Guidelines on Sexuality, Fertility, Pregnancy, and Lactation. J Crohns Colitis 2023;17:1-27. [PubMed: 36005814]
Substance Identification
Substance Name
Thalidomide
CAS Registry Number
50-35-1
Drug Class
Breast Feeding
Milk, Human
Immunosuppressive Agents
Leprostatic Agents
Angiogenesis Inhibitors
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Synthesis and Biological Evaluation of Thalidomide Derivatives as Potential Anti-Psoriasis Agents.[Int J Mol Sci. 2018]Synthesis and Biological Evaluation of Thalidomide Derivatives as Potential Anti-Psoriasis Agents.Tang KW, Lin ZC, Chen YL, Tzeng CC, Fang JY, Tseng CH. Int J Mol Sci. 2018 Oct 7; 19(10). Epub 2018 Oct 7.
- Facile skin targeting of a thalidomide analog containing benzyl chloride moiety alleviates experimental psoriasis via the suppression of MAPK/NF-κB/AP-1 phosphorylation in keratinocytes.[J Dermatol Sci. 2020]Facile skin targeting of a thalidomide analog containing benzyl chloride moiety alleviates experimental psoriasis via the suppression of MAPK/NF-κB/AP-1 phosphorylation in keratinocytes.Tang KW, Lin ZC, Wang PW, Alalaiwe A, Tseng CH, Fang JY. J Dermatol Sci. 2020 Aug; 99(2):90-99. Epub 2020 Jun 21.
- Review Thalomid (Thalidomide) capsules: a review of the first 18 months of spontaneous postmarketing adverse event surveillance, including off-label prescribing.[Drug Saf. 2001]Review Thalomid (Thalidomide) capsules: a review of the first 18 months of spontaneous postmarketing adverse event surveillance, including off-label prescribing.Clark TE, Edom N, Larson J, Lindsey LJ. Drug Saf. 2001; 24(2):87-117.
- Thalidomide--the story goes on...[Notes Undergr. 1998]Thalidomide--the story goes on...Learned J. Notes Undergr. 1998 Sep-Oct; (No 37):1, 7, 9.
- Review Colchicine.[Drugs and Lactation Database (...]Review Colchicine.. Drugs and Lactation Database (LactMed®). 2006
- Thalidomide - Drugs and Lactation Database (LactMed®)Thalidomide - Drugs and Lactation Database (LactMed®)
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