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Report for CCDS11740.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
11740.2 Public Homo sapiens 17 ZACN 24 110 108 CCDS HistoryNCBI Gene:353174Re-query CCDS DB by CCDS ID:11740.2See the combined annotation on chromosome 17 in Sequence Viewer

Public Note for CCDS 11740.1
The coding region has been updated to extend the N-terminus to one that is more supported by available transcript and conservation data. Two possible start codons are present in this update, with the downstream start codon having a stronger Kozak signal. Due to leaky scanning by ribosomes, it is possible that some ribosomes may initiate translation from the upstream AUG codon while others start from the downstream AUG. Translation initiation from the downstream AUG would result in a protein that is 1 aa shorter at the N-terminus.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 11740.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000334586.10 ENSP00000334854.5 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000334586.10Link to Ensembl Protein Viewer:ENSP00000334854.5Re-query CCDS DB by Nucleotide ID:ENST00000334586Re-query CCDS DB by Protein ID:ENSP00000334854
Original member Current member NCBI NM_180990.4 NP_851321.2 MANE Select Accepted alive Link to Nucleotide Sequence:NM_180990.4Link to Protein Sequence:NP_851321.2Re-query CCDS DB by Nucleotide ID:NM_180990Re-query CCDS DB by Protein ID:NP_851321Link to BLAST:NP_851321.2

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_851321.2 412 Q401N2-1 412 100% 0 0

Chromosomal Locations for CCDS 11740.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 17 (NC_000017.11)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17See the combined annotation on chromosome 17 in Sequence Viewer

Chromosome Start Stop Links
17 76079265 76079361 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17
17 76079439 76079563 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17
17 76079702 76079746 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17
17 76079888 76079994 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17
17 76080255 76080424 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17
17 76081278 76081402 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17
17 76081545 76081755 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17
17 76081882 76082049 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17
17 76082463 76082653 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (1239 nt):
ATGATGGCCCTATGGTCCCTGCTCCATCTCACCTTCCTGGGGTTCAGCATTACCTTGCTGTTGGTCCACG
GGCAGGGCTTCCAAGGGACAGCAGCCATCTGGCCATCCCTCTTCAACGTCAACTTGTCCAAGAAGGTTCA
GGAAAGCATCCAGATCCCGAACAATGGGAGTGCGCCCCTGCTCGTGGATGTGCGGGTGTTTGTCTCCAAC
GTGTTTAATGTGGACATCCTGCGATACACAATGTCCTCCATGCTGCTGCTTAGGCTGTCCTGGCTGGACA
CTCGCCTGGCCTGGAACACTAGTGCACACCCGCGGCACGCCATCACGCTGCCCTGGGAGTCTCTCTGGAC
ACCAAGGCTCACCATCCTGGAGGCGCTCTGGGTGGACTGGAGGGACCAGAGCCCCCAGGCTCGAGTAGAC
CAGGACGGCCACGTGAAGCTCAACCTGGCCCTCGCCACGGAGACCAACTGCAACTTTGAGCTCCTCCACT
TCCCCCGGGACCACAGCAACTGCAGCCTCAGCTTCTACGCTCTCAGCAACACGGCGATGGAGTTAGAGTT
CCAGGCCCACGTGGTGAACGAGATTGTGAGTGTCAAGAGGGAATACGTAGTTTATGATCTGAAGACCCAA
GTCCCACCCCAGCAGCTGGTGCCCTGCTTCCAGGTGACGCTGAGGCTGAAGAACACGGCGCTCAAGTCCA
TCATCGCTCTCTTGGTGCCTGCAGAGGCACTGCTGTTGGCTGACGTGTGCGGGGGGTTGCTGCCCCTCCG
GGCCATTGAGCGCATAGGCTACAAGGTGACATTGCTGCTGAGTTACCTCGTCCTCCACTCCTCCCTGGTG
CAGGCCCTGCCCAGCTCCTCCTCCTGCAACCCACTGCTCATTTACTACTTCACCATCCTGCTGCTGCTGC
TCTTCCTCAGCACCATAGAGACTGTGCTGCTGGCTGGGCTGCTGGCCCGGGGCAACCTTGGGGCCAAGAG
CGGCCCCAGCCCAGCCCCGAGAGGGGAACAGCGAGAGCACGGCAACCCAGGGCCTCATCCTGCTGAAGAG
CCCTCCAGAGGAGTAAAGGGGTCACAGAGAAGCTGGCCTGAGACTGCTGACCGCATCTTCTTCCTCGTGT
ATGTGGTTGGGGTGCTGTGCACCCAATTCGTCTTTGCAGGAATCTGGATGTGGGCAGCGTGCAAGTCTGA
CGCAGCCCCTGGAGAGGCTGCACCCCATGGCAGGCGGCCTAGACTGTAA

Translation (412 aa):
MMALWSLLHLTFLGFSITLLLVHGQGFQGTAAIWPSLFNVNLSKKVQESIQIPNNGSAPLLVDVRVFVSN
VFNVDILRYTMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVD
QDGHVKLNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQAHVVNEIVSVKREYVVYDLKTQ
VPPQQLVPCFQVTLRLKNTALKSIIALLVPAEALLLADVCGGLLPLRAIERIGYKVTLLLSYLVLHSSLV
QALPSSSSCNPLLIYYFTILLLLLFLSTIETVLLAGLLARGNLGAKSGPSPAPRGEQREHGNPGPHPAEE
PSRGVKGSQRSWPETADRIFFLVYVVGVLCTQFVFAGIWMWAACKSDAAPGEAAPHGRRPRL


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 Links to:   History report
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