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Report for CCDS22210.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
22210.2 Public Mus musculus 8 Adgra2 23 108 98 CCDS HistoryNCBI Gene:78560Re-query CCDS DB by CCDS ID:22210.2See the combined annotation on chromosome 8 in Sequence Viewer

Public Note for CCDS 22210.1
The coding region has been updated to extend the N-terminus to one that is more supported by available transcript and conservation data. The use of an alternative upstream start codon would result in a protein that is 7 aa longer. It should be noted that an upstream ORF (uORF), which has a strong Kozak signal and encodes 2 aa, overlaps the updated start codon by 1 nt. This uORF may inhibit the use of the upstream start codon, and therefore allow the downstream start codon to be used via a reinitiation shunt mechanism. Alternatively, low level leaky scanning past the uORF start, or translation reinitiation due to the minimal overlap, may allow the upstream start codon to be used. There is no experimental evidence indicating which start codon is preferentially used in vivo.

Public since: CCDS release 2, NCBI annotation release 36.1, Ensembl annotation release 39

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 22210.2

Original Current Source Nucleotide ID Protein ID Status in CCDS Seq. Status Links
Original member Current member EBI ENSMUST00000033876.13 ENSMUSP00000033876.7 Accepted alive Link to Ensembl Transcript Viewer:ENSMUST00000033876.13Link to Ensembl Protein Viewer:ENSMUSP00000033876.7Re-query CCDS DB by Nucleotide ID:ENSMUST00000033876Re-query CCDS DB by Protein ID:ENSMUSP00000033876
Original member Current member NCBI NM_054044.2 NP_473385.2 Accepted alive Link to Nucleotide Sequence:NM_054044.2Link to Protein Sequence:NP_473385.2Re-query CCDS DB by Nucleotide ID:NM_054044Re-query CCDS DB by Protein ID:NP_473385Link to BLAST:NP_473385.2

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_473385.2 1336 Q91ZV8 1336 100% 0 0

Chromosomal Locations for CCDS 22210.2

Assembly GRCm38.p6 (GCF_000001635.26)

On '+' strand of Chromosome 8 (NC_000074.6)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8See the combined annotation on chromosome 8 in Sequence Viewer

Chromosome Start Stop Links
8 27085946 27086211 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27098786 27098857 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27109328 27109399 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27109701 27109772 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27109941 27110012 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27110435 27110598 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27111052 27111265 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27112343 27112507 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27113286 27113484 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27114080 27114229 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27114345 27114506 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27115237 27115461 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27115655 27115874 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27117316 27117515 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27118724 27118851 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27119134 27119257 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27119706 27119851 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27120447 27120536 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 27120766 27122035 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (4011 nt):
ATGGGCGCGGGGGGACGCAGGATGCCGGTGCCTCCCGCGCGTTTGCTGCTGCTGCCGCTGCTGCCTTGTC
TTCTGCTCCTGGCTCCTGGAACTCGGGGTGCGCCTGGCTGCCCGGTCCCTATCCGCGGTTGCAAGTGCTC
TGGGGAGCGGCCCAAGGGACTAAGTGGCGGCGCCCACAACCCGGCTCGAAGGAGGGTGGTGTGCGGCGGT
GGGGATCTCCCCGAACCTCCAGATCCCGGCCTTCTGCCAAACGGCACCATCACCTTGCTCTTGAGCAACA
ACAAGATTACTGGGCTCCGCAATGGATCCTTCTTGGGACTGTCCCTGTTGGAGAAGTTGGACCTGAGGAG
CAATGTCATCAGCACTGTGCAGCCTGGAGCCTTCCTAGGTCTGGGAGAGCTAAAACGCTTAGATCTCTCC
AACAATCGGATTGGCTGTCTCACCTCTGAGACATTTCAAGGGCTCCCTAGACTTCTCAGACTAAACATAT
CTGGAAACATCTACTCTAGTCTGCAACCTGGGGTCTTTGATGAGCTGCCAGCCCTTAAGATTGTGGACTT
TGGTACTGAGTTTCTGACCTGTGACTGCCGCCTGCGCTGGCTGCTGCCCTGGGCCCGGAATCACTCCCTG
CAGCTGTCTGAGCGCACACTCTGTGCCTACCCCAGTGCCCTGCACGCCCATGCCCTGAGCAGCCTCCAGG
AGTCCCAGCTTCGCTGTGAAGGGGCCCTGGAACTGCACACCCACTACCTCATCCCATCCCTTCGCCAAGT
GGTGTTCCAGGGTGACCGCCTGCCCTTCCAGTGCTCAGCCAGCTACTTGGGCAACGATACCCGGATCCAC
TGGTACCACAATGGGGCTCCTATGGAGAGCGATGAGCAGGCCGGCATCGTCCTTGCTGAAAACCTTATCC
ATGATTGCACCTTCATCACCAGTGAGCTGACCCTGTCTCACATTGGTGTGTGGGCCTCTGGTGAATGGGA
GTGCTCCGTGTCCACAGTCCAAGGCAACACCAGCAAGAAGGTGGAGATAGTAGTGCTGGAGACCTCTGCC
TCCTACTGCCCTGCAGAGCGGGTGACCAACAACCGTGGGGACTTCAGGTGGCCCCGAACCTTGGCTGGCA
TCACGGCTTACCAGTCCTGTTTACAGTACCCCTTCACCTCTGTGCCCTTGAGTGGGGGAGCCCCGGGTAC
CCGAGCCTCACGCAGGTGTGACCGAGCTGGCCGCTGGGAGCCAGGGGACTACTCGCACTGTCTGTACACC
AATGACATCACTCGGGTGCTCTACACCTTTGTGCTGATGCCCATCAACGCCTCCAATGCATTGACGTTGG
CCCACCAGCTGCGAGTGTATACCGCAGAGGCCGCCAGCTTCTCAGACATGATGGACGTGGTCTATGTGGC
TCAGATGATCCAGAAGTTTTTGGGTTACGTTGACCAGATCAAGGAGCTGGTGGAGGTGATGGTGGACATG
GCCAGCAACCTGATGCTGGTGGATGAGCACCTTCTGTGGCTGGCCCAGAGAGAAGACAAAGCCTGCAGTG
GCATTGTGGGTGCCCTGGAGCGAATCGGAGGAGCTGCTCTTAGCCCCCATGCCCAGCACATCTCTGTGAA
TTCAAGAAATGTGGCACTGGAGGCCTACCTCATCAAGCCTCACAGCTACGTGGGTCTGACTTGCACGGCT
TTCCAGAGGAGGGAGGTAGGAGTGTCGGGTGCACAGCCAAGCAGCGTCGGCCAGGATGCCCCAGTGGAGC
CCGAACCCCTAGCTGATCAGCAGCTTAGGTTCCGCTGCACCACTGGGAGGCCCAACATTTCTCTGTCATC
CTTCCACATCAAGAATAGCGTGGCCCTGGCCTCCATCCAGCTGCCCCCCAGCCTGTTCTCAACCCTTCCG
GCTGCCCTGGCTCCCCCAGTCCCTCCAGATTGCACCCTGCAACTGCTGGTCTTCAGAAATGGCCGTCTTT
TCCGCAGCCACGGCAACAACACTTCCCGTCCTGGAGCAGCTGGGCCTGGCAAGAGGCGTGGTGTGGCCAC
CCCAGTCATATTTGCAGGAACCAGTGGCTGTGGTGTGGGAAACTTGACGGAGCCCGTGGCTGTGTCACTG
AGGCACTGGGCTGAAGGAGCTGACCCCATGGCAGCTTGGTGGAACCAGGACGGGCCTGGAGGCTGGAGTT
CTGAAGGCTGCAGGCTCCGCTACAGCCAGCCCAACGTCAGCTCCCTGTACTGCCAGCACTTGGGCAATGT
GGCCGTGCTTATGGAGCTGAATGCATTCCCGCGGGAGGCAGGAGGCTCTGGGGCTGGGTTGCATCCCGTC
GTGTACCCCTGCACGGCTTTGCTGCTACTCTGTCTCTTCTCCACCATCATCACGTACATCCTCAACCACA
GCTCCATCCACGTGTCCCGGAAGGGTTGGCACATGCTGCTGAACCTTTGTTTCCATATGGCCATGACCTC
TGCTGTCTTCGTGGGGGGCGTCACGCTCACCAACTACCAAATGGTTTGTCAAGCGGTGGGCATCACTCTG
CACTACTCTTCCTTGTCGTCACTGCTCTGGATGGGGGTCAAGGCTCGAGTCCTCCACAAGGAGCTTAGTT
GGAGGGCACCCCCTCTGGAAGAAGGGGAAGCAGCTCCGCCTGGTCCTCGCCCCATGCTCCGGTTCTACTT
GATTGCTGGAGGGATCCCCCTCATAATCTGCGGCATCACCGCTGCGGTCAACATCCACAACTACCGGGAC
CACAGTCCCTATTGTTGGCTGGTGTGGCGTCCAAGCCTTGGTGCCTTCTACATACCGGTGGCGTTGATTC
TGCCTATCACCTGGATCTACTTCTTGTGTGCAGGCCTTCACTTACGGAGCCATGTGGCCCAGAATCCAAA
GCAGGGTAACAGGATCTCTCTGGAGCCAGGGGAAGAGCTGAGGGGTTCCACCAGGCTCAGGAGTAGTGGC
GTCCTCCTGAATGACTCTGGTTCTCTTTTGGCTACAGTTAGCGCAGGAGTAGGGACACCTGCGCCCCCAG
AGGATGGTGATGGCGTATATTCTCCTGGAGTCCAGCTGGGGGCGCTGATGACCACGCATTTCCTGTACCT
GGCTATGTGGGCTTGTGGTGCCTTGGCGGTGTCTCAGCGCTGGCTGCCCCGAGTGGTGTGTAGCTGTCTG
TACGGCGTGGCAGCTTCAGCTCTTGGTCTGTTTGTCTTCACTCACCACTGTGCCAGACGTAGAGATGTCC
GGGCTTCCTGGCGCGCCTGCTGCCCTCCTGCTTCGCCCTCGGCCTCCCATGTCCCAGCCCGGGCCCTGCC
GACTGCTACAGAGGATGGATCCCCAGTGTTGGGGGAGGGACCAGCCTCTCTCAAGTCCTCCCCAAGTGGC
AGCAGTGGCCGCGCGCCGCCACCCCCCTGCAAACTCACCAATCTGCAGGTGGCCCAGAGTCAGGTGTGCG
AGGCAAGCGTGGCCGCCCGCGGAGATGGAGAGCCAGAGCCCACCGGCTCCCGTGGCAGCCTAGCTCCCCG
GCACCATAACAACCTGCATCATGGGCGCCGAGTACACAAGAGTCGGGCCAAGGGGCACCGAGCCGGAGAG
ACTGGTGGTAAGAGCCGGCTCAAGGCGTTGCGCGCGGGCACGTCCCCAGGAGCTCCCGAGCTGTTGTCCA
GTGAGAGCGGCAGTTTGCACAACAGCCCGTCTGACAGCTACCCGGGCAGCAGCCGCAACAGTCCAGGCGA
CGGTCTTCCACTCGAGGGTGAGCCCATGCTTACGCCGTCGGAGGGCAGTGACACAAGCGCCGCGCCAATC
GCTGAGACGGGGCGCCCCGGGCAGCGCCGCAGCGCCAGCCGTGACAACCTCAAGGGCAGCGGCAGCGCGC
TGGAGAGGGAGAGCAAGCGCCGCTCCTATCCGCTCAACACTACCAGTCTTAACGGTGCCCCCAAAGGGGG
CAAGTATGAGGATGCCAGTGTAACTGGTGCAGAGGCCATAGCGGGAGGCTCCATGAAGACTGGCCTCTGG
AAAAGCGAGACCACCGTCTAG

Translation (1336 aa):
MGAGGRRMPVPPARLLLLPLLPCLLLLAPGTRGAPGCPVPIRGCKCSGERPKGLSGGAHNPARRRVVCGG
GDLPEPPDPGLLPNGTITLLLSNNKITGLRNGSFLGLSLLEKLDLRSNVISTVQPGAFLGLGELKRLDLS
NNRIGCLTSETFQGLPRLLRLNISGNIYSSLQPGVFDELPALKIVDFGTEFLTCDCRLRWLLPWARNHSL
QLSERTLCAYPSALHAHALSSLQESQLRCEGALELHTHYLIPSLRQVVFQGDRLPFQCSASYLGNDTRIH
WYHNGAPMESDEQAGIVLAENLIHDCTFITSELTLSHIGVWASGEWECSVSTVQGNTSKKVEIVVLETSA
SYCPAERVTNNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSGGAPGTRASRRCDRAGRWEPGDYSHCLYT
NDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDM
ASNLMLVDEHLLWLAQREDKACSGIVGALERIGGAALSPHAQHISVNSRNVALEAYLIKPHSYVGLTCTA
FQRREVGVSGAQPSSVGQDAPVEPEPLADQQLRFRCTTGRPNISLSSFHIKNSVALASIQLPPSLFSTLP
AALAPPVPPDCTLQLLVFRNGRLFRSHGNNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSL
RHWAEGADPMAAWWNQDGPGGWSSEGCRLRYSQPNVSSLYCQHLGNVAVLMELNAFPREAGGSGAGLHPV
VYPCTALLLLCLFSTIITYILNHSSIHVSRKGWHMLLNLCFHMAMTSAVFVGGVTLTNYQMVCQAVGITL
HYSSLSSLLWMGVKARVLHKELSWRAPPLEEGEAAPPGPRPMLRFYLIAGGIPLIICGITAAVNIHNYRD
HSPYCWLVWRPSLGAFYIPVALILPITWIYFLCAGLHLRSHVAQNPKQGNRISLEPGEELRGSTRLRSSG
VLLNDSGSLLATVSAGVGTPAPPEDGDGVYSPGVQLGALMTTHFLYLAMWACGALAVSQRWLPRVVCSCL
YGVAASALGLFVFTHHCARRRDVRASWRACCPPASPSASHVPARALPTATEDGSPVLGEGPASLKSSPSG
SSGRAPPPPCKLTNLQVAQSQVCEASVAARGDGEPEPTGSRGSLAPRHHNNLHHGRRVHKSRAKGHRAGE
TGGKSRLKALRAGTSPGAPELLSSESGSLHNSPSDSYPGSSRNSPGDGLPLEGEPMLTPSEGSDTSAAPI
AETGRPGQRRSASRDNLKGSGSALERESKRRSYPLNTTSLNGAPKGGKYEDASVTGAEAIAGGSMKTGLW
KSETTV


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

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