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Report for CCDS46366.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
46366.2 Public Homo sapiens 2 FAM178B 24 110 108 CCDS HistoryNCBI Gene:51252Re-query CCDS DB by CCDS ID:46366.2Re-query CCDS DB by GeneID:51252See the combined annotation on chromosome 2 in Sequence Viewer

Public Note for CCDS 46366.1
The coding region has been updated to extend the N-terminus and represent the 5'-most in-frame start codon. This start codon is not conserved in any other species. Two alternative downstream start codons, which are more widely conserved, also exist. It is possible that leaky scanning by ribosomes would allow the downstream start codons to be used, at least some of the time. Use of the downstream start codons would result in a protein that is either 26 aa or 32 aa shorter at the N-terminus. There is no experimental evidence showing which start codon is preferentially used in vivo.

Public since: CCDS release 6, NCBI annotation release 37.1, Ensembl annotation release 55

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 46366.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000490605.3 ENSP00000429896.1 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000490605.3Link to Ensembl Protein Viewer:ENSP00000429896.1Re-query CCDS DB by Nucleotide ID:ENST00000490605Re-query CCDS DB by Protein ID:ENSP00000429896
Original member Current member NCBI NM_001122646.3 NP_001116118.2 MANE Select Accepted alive Link to Nucleotide Sequence:NM_001122646.3Link to Protein Sequence:NP_001116118.2Re-query CCDS DB by Nucleotide ID:NM_001122646Re-query CCDS DB by Protein ID:NP_001116118Link to BLAST:NP_001116118.2

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_001116118.2 679 Q8IXR5-3 679 100% 0 0

Chromosomal Locations for CCDS 46366.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 2 (NC_000002.12)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2See the combined annotation on chromosome 2 in Sequence Viewer

Chromosome Start Stop Links
2 96876276 96876308 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96877890 96878042 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96878416 96878493 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96893926 96894051 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96902620 96902707 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96921165 96921262 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96921478 96921654 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96923490 96923583 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96929206 96929320 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96947818 96947902 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96951379 96951484 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96960288 96960440 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96967520 96967627 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96970716 96970777 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96971901 96972322 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96972538 96972606 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 96986241 96986313 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (2040 nt):
ATGTGGCCAAGGCTTCCAGGTGCGGGCCTCGCTCCACAACTCAGGAGGCAGGATCAGCGGCTCCATTTTA
CAGGACAGATGTCCCACGGCTTGCAGATGGCTGGGCCCCAGGAGACGGTGCTAGCCCTTCCTCTGAGAGA
AGGGGTGCAGGCTGCCGCCACCGTGCCCATCCTCCTGTACAACCTGGAGGATGGCTTGTCAGACCATCCC
CTGGACCAGGGGCCCCGCTGCCCTGCCCGGCGGCCCTGCAGCCCTGCCTCGGCTCCAGCTCCCACATCGC
CAAAGAAGCCCAAGATACAGGCACCTGGGGAAACGTTTCCCACTGACTGGAGCCCCCCGCCCGTGGAATT
CCTCAACCCGAGGGTGCTGCAGGCCAGTCGGGAGGCCCCGGCCCAGAGGTGGGTGGGTGTGGTGGGCCCC
CAGGGCCTGAGGAGACTGGCTGGTGAGCTGCCCGAGGAGTTGGAGCAGGAACACCTGGACTTGGACCCGA
AGAGGGGCCTGGCCTTGCCAGAGAAGCTGTTCTGGAACACGTCAGGCCTGAGCCAGCAGGCTGCGGCCCC
AGAGTTTTCCTGGGGGGGCTCAGGAAGCTACTTCAACAACCTGGACTACTTACTGCAGGAGAAGAGGGAA
CAGGCCCTGGAGCAGGAGCGAGAGAGGCTGCTTCTGCAGGAGTGTCTCAATCTCAACTCCTTGGATCTTG
ATGAAGAGGAAGTGCCACTCACACCCGAGCACAGGATGCTGGTGGAAAAGTACTCAGTGTCCCTGCAGAC
CATCCCGCCGGTCCATCCAGGTGAGACTGTGTTTCTGCCCAGGTGTCACCCCCTGCCATGCATCCTGGAC
TCCTCACTCCTGAAGCCACGCAGCCACCTGGAAGGGCTGTTCCTCAGCTCCCCGCCAGCCCAACAGCTCT
CCTTCCTGCGCAGTGGCCTCCTGAACATCCTCTACCTGCACATGCCTGACTGCCCGGTATCCCTGCTCCA
GTGGCTGTTCCAGCTGCTGACATGGCCTCCAGAAACATCTTTGGGAGCCTTTGGTCTTCTGTGGGATCTC
ATTGTGGATGGAATCTTCCTTCAGCCTGATGAAGACAAGCACCTGTGGTGCCCCTCACTGCAAGAAGTCA
GGGAGGCATTCCACAGCCTGGGTGCCCACAGTCCTGCCCTGTACCCTCTGGGGCCCTTTTGGCACGGTGG
CAGGGTGCTTCCAGGCGAGGCTGGCCTGAATGAGAATGAGGAGCAGGACGCTCCCCAAGAGATTGCCTTG
GACATCAGCCTGGGCCACATCTACAAGTTTCTGGCGCTGTGTGCCCAGGCCCAGCCGGGGGCCTACACTG
ATGAGAACCTCATGGGACTGATTGAGCTGCTGTGCCGCACCAGCCTGGACGTGGGGCTCCGCCTGCTGCC
CAAAGTTGACCTCCAGCAGCTTCTCCTCTTGCTCCTGGAGAACATCCGGGAGTGGCCAGGGAAGCTCCAG
GAACTGTGCTGCACCCTGAGCTGGGTGTCTGACCACCACCACAACCTGCTGGCCCTCGTGCAGTTCTTCC
CAGACATGACCTCCCGGAGCAGGCGGCTTCGAAGCCAGCTCAGCCTTGTGGTCATTGCTCGAATGCTGGG
CCAGCAGGAGATGCTCCCTCTCTGGCAAGAGAAGACCCAGCTGTCCTCGCTCAGCCGGCTCCTGGGCCTC
ATGAGGCCATCATCTCTCAGGCAATACCTGGACTCTGTGCCCTTGCCACCCTGCCAGGAGCAACAGCCAA
AGGCTAGTGCCGAGCTAGACCACAAGGCCTGCTACCTGTGCCACAGCTTGCTGATGCTGGCCGGGGTAGT
TGTTAGCTGCCAGGACATCACTCCAGACCAGTGGGGCGAGCTGCAGCTGCTGTGCATGCAGTTGGACCGC
CACATCAGCACGCAGATCCGGGAGAGCCCCCAGGCCATGCACCGCACCATGCTCAAGGACCTGGCTACCC
AGACCTACATCCGTTGGCAGGAGCTGCTGACCCACTGCCAGCCCCAGGCCCAGTATTTCAGCCCCTGGAA
AGACATCTAA

Translation (679 aa):
MWPRLPGAGLAPQLRRQDQRLHFTGQMSHGLQMAGPQETVLALPLREGVQAAATVPILLYNLEDGLSDHP
LDQGPRCPARRPCSPASAPAPTSPKKPKIQAPGETFPTDWSPPPVEFLNPRVLQASREAPAQRWVGVVGP
QGLRRLAGELPEELEQEHLDLDPKRGLALPEKLFWNTSGLSQQAAAPEFSWGGSGSYFNNLDYLLQEKRE
QALEQERERLLLQECLNLNSLDLDEEEVPLTPEHRMLVEKYSVSLQTIPPVHPGETVFLPRCHPLPCILD
SSLLKPRSHLEGLFLSSPPAQQLSFLRSGLLNILYLHMPDCPVSLLQWLFQLLTWPPETSLGAFGLLWDL
IVDGIFLQPDEDKHLWCPSLQEVREAFHSLGAHSPALYPLGPFWHGGRVLPGEAGLNENEEQDAPQEIAL
DISLGHIYKFLALCAQAQPGAYTDENLMGLIELLCRTSLDVGLRLLPKVDLQQLLLLLLENIREWPGKLQ
ELCCTLSWVSDHHHNLLALVQFFPDMTSRSRRLRSQLSLVVIARMLGQQEMLPLWQEKTQLSSLSRLLGL
MRPSSLRQYLDSVPLPPCQEQQPKASAELDHKACYLCHSLLMLAGVVVSCQDITPDQWGELQLLCMQLDR
HISTQIRESPQAMHRTMLKDLATQTYIRWQELLTHCQPQAQYFSPWKDI


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

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