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Conserved domains on  [gi|2247715262|pdb|7OLN|AAA]
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Chain AAA, Lectin

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bc2l-C_N cd12211
N-Terminal Domain Of Bc2l-C Lectin; Lectin BC2L-C of Burkholderia cenocepacia is one of ...
 5-134 6.33e-88

N-Terminal Domain Of Bc2l-C Lectin; Lectin BC2L-C of Burkholderia cenocepacia is one of several lectins produced by this pathogen. BC2L-C has been shown to bind fucosylated human histo-blood group epitopes H-type 1, Lewis B, and Lewis Y. The C-terminal domain resembles BC2L-A, a calcium dependent mannose-binding protein. The N-terminal domain trimerizes and binds alpha-MeSeFuc in pockets between the monomeric units. The N-terminal domain has a similar structure to tumor necrosis factor (TNF).


:

Pssm-ID: 213404  Cd Length: 131  Bit Score: 251.77  E-value: 6.33e-88
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7OLN_AAA      5 LLSASIVSAPVVTSETYVDIPGLYLDVAKAGIRDGKLQVILNVPTPYATGNNFPGIYFAIATNQGVVADGCFTYSSKVPE 84
Cdd:cd12211   1 LLSASIVSAPVVTSETYVDIPGLYLDVAKAGIRDGKLQVILNVPTPYATGNNFPGIYFAIATNQGVVADGCFTYSSKVPE 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
7OLN_AAA     85 STGRMPFTLVATIDVGSGVTFVKGQWKSVRGSAMHIDSYASLSAIWGTAA 134
Cdd:cd12211  81 STGRMPFTLVATIDVGSGVTFVKGQWKSVRGSAMHIDSYASLSAIGGTAA 130
 
Name Accession Description Interval E-value
Bc2l-C_N cd12211
N-Terminal Domain Of Bc2l-C Lectin; Lectin BC2L-C of Burkholderia cenocepacia is one of ...
 5-134 6.33e-88

N-Terminal Domain Of Bc2l-C Lectin; Lectin BC2L-C of Burkholderia cenocepacia is one of several lectins produced by this pathogen. BC2L-C has been shown to bind fucosylated human histo-blood group epitopes H-type 1, Lewis B, and Lewis Y. The C-terminal domain resembles BC2L-A, a calcium dependent mannose-binding protein. The N-terminal domain trimerizes and binds alpha-MeSeFuc in pockets between the monomeric units. The N-terminal domain has a similar structure to tumor necrosis factor (TNF).


Pssm-ID: 213404  Cd Length: 131  Bit Score: 251.77  E-value: 6.33e-88
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7OLN_AAA      5 LLSASIVSAPVVTSETYVDIPGLYLDVAKAGIRDGKLQVILNVPTPYATGNNFPGIYFAIATNQGVVADGCFTYSSKVPE 84
Cdd:cd12211   1 LLSASIVSAPVVTSETYVDIPGLYLDVAKAGIRDGKLQVILNVPTPYATGNNFPGIYFAIATNQGVVADGCFTYSSKVPE 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
7OLN_AAA     85 STGRMPFTLVATIDVGSGVTFVKGQWKSVRGSAMHIDSYASLSAIWGTAA 134
Cdd:cd12211  81 STGRMPFTLVATIDVGSGVTFVKGQWKSVRGSAMHIDSYASLSAIGGTAA 130
 
Name Accession Description Interval E-value
Bc2l-C_N cd12211
N-Terminal Domain Of Bc2l-C Lectin; Lectin BC2L-C of Burkholderia cenocepacia is one of ...
 5-134 6.33e-88

N-Terminal Domain Of Bc2l-C Lectin; Lectin BC2L-C of Burkholderia cenocepacia is one of several lectins produced by this pathogen. BC2L-C has been shown to bind fucosylated human histo-blood group epitopes H-type 1, Lewis B, and Lewis Y. The C-terminal domain resembles BC2L-A, a calcium dependent mannose-binding protein. The N-terminal domain trimerizes and binds alpha-MeSeFuc in pockets between the monomeric units. The N-terminal domain has a similar structure to tumor necrosis factor (TNF).


Pssm-ID: 213404  Cd Length: 131  Bit Score: 251.77  E-value: 6.33e-88
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7OLN_AAA      5 LLSASIVSAPVVTSETYVDIPGLYLDVAKAGIRDGKLQVILNVPTPYATGNNFPGIYFAIATNQGVVADGCFTYSSKVPE 84
Cdd:cd12211   1 LLSASIVSAPVVTSETYVDIPGLYLDVAKAGIRDGKLQVILNVPTPYATGNNFPGIYFAIATNQGVVADGCFTYSSKVPE 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
7OLN_AAA     85 STGRMPFTLVATIDVGSGVTFVKGQWKSVRGSAMHIDSYASLSAIWGTAA 134
Cdd:cd12211  81 STGRMPFTLVATIDVGSGVTFVKGQWKSVRGSAMHIDSYASLSAIGGTAA 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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