NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2557041678|pdb|8EDG|I]
View 

Chain I, Hermes transposase

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
DBD_Tnp_Hermes pfam10683
Hermes transposase DNA-binding domain; This domain confers specific DNA-binding on Hermes ...
80-146 1.38e-36

Hermes transposase DNA-binding domain; This domain confers specific DNA-binding on Hermes transposase.


:

Pssm-ID: 402358  Cd Length: 67  Bit Score: 130.74  E-value: 1.38e-36
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
8EDG_I         80 SRELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPIT 146
Cdd:pfam10683   1 SQELKTVSEEDKKEAIEKCTQWVVRDCRPFSAVTGSGFIKLVKFFIKIGASYGEHVDVEDLLPSPTT 67
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
523-602 1.91e-16

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


:

Pssm-ID: 399013  Cd Length: 83  Bit Score: 74.61  E-value: 1.91e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8EDG_I        523 EFEFYRKEIVI-LSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLN 601
Cdd:pfam05699   1 ELDQYLSEPVLpRNEDFDPLEWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRLEPLNVEALLCIE 80

                  .
8EDG_I        602 S 602
Cdd:pfam05699  81 D 81
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
29-73 3.89e-07

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


:

Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 47.04  E-value: 3.89e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
8EDG_I          29 FIWNVLADIQKEDDTLveGWVFCRKCEKVLKYTTR-QTSNLCRHKC 73
Cdd:smart00614   1 KVWKHFTLILEKDNGK--QRAKCKYCGKKLSRSSKgGTSNLRRHLR 44
 
Name Accession Description Interval E-value
DBD_Tnp_Hermes pfam10683
Hermes transposase DNA-binding domain; This domain confers specific DNA-binding on Hermes ...
80-146 1.38e-36

Hermes transposase DNA-binding domain; This domain confers specific DNA-binding on Hermes transposase.


Pssm-ID: 402358  Cd Length: 67  Bit Score: 130.74  E-value: 1.38e-36
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
8EDG_I         80 SRELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPIT 146
Cdd:pfam10683   1 SQELKTVSEEDKKEAIEKCTQWVVRDCRPFSAVTGSGFIKLVKFFIKIGASYGEHVDVEDLLPSPTT 67
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
523-602 1.91e-16

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 74.61  E-value: 1.91e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8EDG_I        523 EFEFYRKEIVI-LSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLN 601
Cdd:pfam05699   1 ELDQYLSEPVLpRNEDFDPLEWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRLEPLNVEALLCIE 80

                  .
8EDG_I        602 S 602
Cdd:pfam05699  81 D 81
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
29-73 3.89e-07

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 47.04  E-value: 3.89e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
8EDG_I          29 FIWNVLADIQKEDDTLveGWVFCRKCEKVLKYTTR-QTSNLCRHKC 73
Cdd:smart00614   1 KVWKHFTLILEKDNGK--QRAKCKYCGKKLSRSSKgGTSNLRRHLR 44
 
Name Accession Description Interval E-value
DBD_Tnp_Hermes pfam10683
Hermes transposase DNA-binding domain; This domain confers specific DNA-binding on Hermes ...
80-146 1.38e-36

Hermes transposase DNA-binding domain; This domain confers specific DNA-binding on Hermes transposase.


Pssm-ID: 402358  Cd Length: 67  Bit Score: 130.74  E-value: 1.38e-36
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
8EDG_I         80 SRELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPIT 146
Cdd:pfam10683   1 SQELKTVSEEDKKEAIEKCTQWVVRDCRPFSAVTGSGFIKLVKFFIKIGASYGEHVDVEDLLPSPTT 67
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
523-602 1.91e-16

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 74.61  E-value: 1.91e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8EDG_I        523 EFEFYRKEIVI-LSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLN 601
Cdd:pfam05699   1 ELDQYLSEPVLpRNEDFDPLEWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRLEPLNVEALLCIE 80

                  .
8EDG_I        602 S 602
Cdd:pfam05699  81 D 81
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
29-73 3.89e-07

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 47.04  E-value: 3.89e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
8EDG_I          29 FIWNVLADIQKEDDTLveGWVFCRKCEKVLKYTTR-QTSNLCRHKC 73
Cdd:smart00614   1 KVWKHFTLILEKDNGK--QRAKCKYCGKKLSRSSKgGTSNLRRHLR 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH