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Concise Results
Standard Results
Full Results
Chain B, Glycine--tRNA ligase
Protein Classification
HD domain-containing protein ( domain architecture ID 229447 )
HD domain-containing protein may function as a metal dependent phosphohydrolase
List of domain hits
Name
Accession
Description
Interval
E-value
HDc super family
cl21469 Metal dependent phosphohydrolases with conserved 'HD' motif
45-1042
0e+00
Metal dependent phosphohydrolases with conserved 'HD' motif
PRK14908 :Pssm-ID: 473873 [Multi-domain]
Cd Length: 1000
Bit Score: 1185.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 45 SS SV LT F Q QAIQR L QD YW ASV GC AVM Q CSNT EVGAGT M NP L TFLRVLGPEPW N VAYVEPS I RPDD S RYG D NPNRLQ RH TQ 124
Cdd:PRK14908 1 SS QP LT M Q DMLLA L LR YW SEQ GC IIH Q GYDL EVGAGT F NP A TFLRVLGPEPW R VAYVEPS R RPDD G RYG Q NPNRLQ TY TQ 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 125 FQVILKP D PGN S Q D L F L H SL S A L GI NV R E HDIRFV E D N WE S P VL GAWGLGWEVW M DGMEITQFTYFQQ S G SL PL L P V S V E 204
Cdd:PRK14908 81 FQVILKP V PGN P Q E L Y L E SL K A I GI DL R D HDIRFV H D D WE N P TI GAWGLGWEVW L DGMEITQFTYFQQ A G GK PL D P I S G E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 205 ITYG L ERI L M S LQ G V D HFK N I QYTK G I TYGE L F LEN E K EMS A Y YLEH AN VDNIQ KHF D D FEE EA RS LL SLW LP I PAYD H V 284
Cdd:PRK14908 161 ITYG I ERI A M Y LQ K V N HFK D I AWND G L TYGE I F QQA E Y EMS R Y NFDD AN TEMWL KHF E D YAA EA LR LL DAG LP V PAYD F V 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 285 LKASHAFNILD S RG FVG VTER A RY FG R M R S LAR QC A Q L W V KT RE N LG Y PL GT yqesn LIY P HVSEK P SRKGVVGQ P RAFV 364
Cdd:PRK14908 241 LKASHAFNILD A RG AIS VTER T RY IA R I R Q LAR AV A D L Y V EW RE E LG F PL LK ----- VPP P PAAVT P KKTPDICG P ETLL 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 365 L EIG T EELP PHD V IEATK QLE KS L IQI L EKR RL SHG K VRSY GTPRRLA VV VE NLNMKQMEE E I E L RGP PVAK AFD QE G R P 444
Cdd:PRK14908 316 F EIG S EELP ATF V PIGIQ QLE SA L REL L ADT RL GYE K LEVL GTPRRLA LL VE DVAPREPDA E R E K RGP RLSA AFD AD G T P 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 445 T K A A EGF C R KNN V P I DS L --------- YR R TDGKT EY IYARVK E SA R F A DEV L TED LP TI I SGIS FPK S MRW N - SNIVFS 514
Cdd:PRK14908 396 T P A G EGF F R SQG V D I SH L saldqdgai EI R EINGV EY LFLVRP E PG R D A AAI L ANE LP EL I QSLR FPK K MRW D d PGLSYA 475
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 515 RPIRW IF AL H GD L IVP FCFAGIS SG NQSC G L R NSSLANFKVEA A EL Y LH TL EK A GILIDMQ ER KQR I LHDSSI LA EG V GG 594
Cdd:PRK14908 476 RPIRW LV AL Y GD Q IVP ISVGTLA SG RTTR G H R QLDPPPVEIPS A DG Y VE TL RQ A CVILSPK ER REI I VQGLQN LA AD V QI 555
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 595 D I IA PDS L VQ EV I NLVE A P MP I I G RY D VS FL A LPK DV LI TV M Q KHQ K YFPV TS k TM G N LL PC F IT VA N G AIKE E V VR k GN 674
Cdd:PRK14908 556 D A IA EPR L ID EV T NLVE H P FV I L G QF D EK FL E LPK EL LI AE M V KHQ R YFPV RD - AQ G T LL NH F VI VA D G SPDD E I VR - GN 633
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 675 E A VLRAR YE D AK F FY K M D TQKK L SE F RDQ L S S ILFH E R LG TML DK MK R VENTVA E V A L LL GINEKM ip AIKD AA A L AMS D 754
Cdd:PRK14908 634 E K VLRAR LT D GA F LF K A D LKTP L ET F VEK L K S VTYF E A LG SLA DK VE R IKAHAE E L A A LL PLSARE -- TLDR AA E L CKF D 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 755 L ATNI V T EF TS L A GIM A R H YA L R D G LS E QI A E AL F E IT LPR FS GD VF P KTDP G IV L AVT DRLD S L V G L F GA G CQ P S S TN D 834
Cdd:PRK14908 712 L VSQM V N EF PE L Q GIM G R Y YA Q R A G EP E AV A Q AL G E HE LPR TA GD SL P ASTT G AL L SLA DRLD N L L G C F AL G LK P T S SS D 791
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 835 P FG LRR ISY G LVQI L VENKKNF DL TKA L TLV A EEQ P --- ITIDSG V I DEV VQ FV TR RL EQL L V D E G INCEIVRS VL IERA 911
Cdd:PRK14908 792 P YA LRR QAL G VLTL L RATPASL DL EDL L ARL A RHF P stt VWVKEA V L DEV LE FV WG RL KTQ L L D L G FDKDEIAA VL PDAC 871
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 912 NC P YL A SQ TA IEMEAFSR TE D F PK I VE A YS R PT RI IRG kei G S ALEV DAS VFEKDE E RA L wsay LEVA D KIHPGV ----- 986
Cdd:PRK14908 872 KN P AE A DK TA QALQELKS TE I F AE I AA A LN R LK RI LAS --- L S FSVT DAS LLLEPA E LN L ---- KQAL D AFREEL telpi 944
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
8H1C_B 987 D I K AFAD A SL EL L Q PLED FF TN V F VMA E DE KV RN N RL A LL TKVAS L PK G IA D LSV L 1042
Cdd:PRK14908 945 D L K DYVA A AA EL P Q AVNT FF DE V L VMA D DE AI RN A RL G LL AAIRD L KF G VL D WDA L 1000
Name
Accession
Description
Interval
E-value
PRK14908
PRK14908 glycine--tRNA ligase;
45-1042
0e+00
glycine--tRNA ligase;
Pssm-ID: 237859 [Multi-domain]
Cd Length: 1000
Bit Score: 1185.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 45 SS SV LT F Q QAIQR L QD YW ASV GC AVM Q CSNT EVGAGT M NP L TFLRVLGPEPW N VAYVEPS I RPDD S RYG D NPNRLQ RH TQ 124
Cdd:PRK14908 1 SS QP LT M Q DMLLA L LR YW SEQ GC IIH Q GYDL EVGAGT F NP A TFLRVLGPEPW R VAYVEPS R RPDD G RYG Q NPNRLQ TY TQ 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 125 FQVILKP D PGN S Q D L F L H SL S A L GI NV R E HDIRFV E D N WE S P VL GAWGLGWEVW M DGMEITQFTYFQQ S G SL PL L P V S V E 204
Cdd:PRK14908 81 FQVILKP V PGN P Q E L Y L E SL K A I GI DL R D HDIRFV H D D WE N P TI GAWGLGWEVW L DGMEITQFTYFQQ A G GK PL D P I S G E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 205 ITYG L ERI L M S LQ G V D HFK N I QYTK G I TYGE L F LEN E K EMS A Y YLEH AN VDNIQ KHF D D FEE EA RS LL SLW LP I PAYD H V 284
Cdd:PRK14908 161 ITYG I ERI A M Y LQ K V N HFK D I AWND G L TYGE I F QQA E Y EMS R Y NFDD AN TEMWL KHF E D YAA EA LR LL DAG LP V PAYD F V 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 285 LKASHAFNILD S RG FVG VTER A RY FG R M R S LAR QC A Q L W V KT RE N LG Y PL GT yqesn LIY P HVSEK P SRKGVVGQ P RAFV 364
Cdd:PRK14908 241 LKASHAFNILD A RG AIS VTER T RY IA R I R Q LAR AV A D L Y V EW RE E LG F PL LK ----- VPP P PAAVT P KKTPDICG P ETLL 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 365 L EIG T EELP PHD V IEATK QLE KS L IQI L EKR RL SHG K VRSY GTPRRLA VV VE NLNMKQMEE E I E L RGP PVAK AFD QE G R P 444
Cdd:PRK14908 316 F EIG S EELP ATF V PIGIQ QLE SA L REL L ADT RL GYE K LEVL GTPRRLA LL VE DVAPREPDA E R E K RGP RLSA AFD AD G T P 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 445 T K A A EGF C R KNN V P I DS L --------- YR R TDGKT EY IYARVK E SA R F A DEV L TED LP TI I SGIS FPK S MRW N - SNIVFS 514
Cdd:PRK14908 396 T P A G EGF F R SQG V D I SH L saldqdgai EI R EINGV EY LFLVRP E PG R D A AAI L ANE LP EL I QSLR FPK K MRW D d PGLSYA 475
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 515 RPIRW IF AL H GD L IVP FCFAGIS SG NQSC G L R NSSLANFKVEA A EL Y LH TL EK A GILIDMQ ER KQR I LHDSSI LA EG V GG 594
Cdd:PRK14908 476 RPIRW LV AL Y GD Q IVP ISVGTLA SG RTTR G H R QLDPPPVEIPS A DG Y VE TL RQ A CVILSPK ER REI I VQGLQN LA AD V QI 555
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 595 D I IA PDS L VQ EV I NLVE A P MP I I G RY D VS FL A LPK DV LI TV M Q KHQ K YFPV TS k TM G N LL PC F IT VA N G AIKE E V VR k GN 674
Cdd:PRK14908 556 D A IA EPR L ID EV T NLVE H P FV I L G QF D EK FL E LPK EL LI AE M V KHQ R YFPV RD - AQ G T LL NH F VI VA D G SPDD E I VR - GN 633
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 675 E A VLRAR YE D AK F FY K M D TQKK L SE F RDQ L S S ILFH E R LG TML DK MK R VENTVA E V A L LL GINEKM ip AIKD AA A L AMS D 754
Cdd:PRK14908 634 E K VLRAR LT D GA F LF K A D LKTP L ET F VEK L K S VTYF E A LG SLA DK VE R IKAHAE E L A A LL PLSARE -- TLDR AA E L CKF D 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 755 L ATNI V T EF TS L A GIM A R H YA L R D G LS E QI A E AL F E IT LPR FS GD VF P KTDP G IV L AVT DRLD S L V G L F GA G CQ P S S TN D 834
Cdd:PRK14908 712 L VSQM V N EF PE L Q GIM G R Y YA Q R A G EP E AV A Q AL G E HE LPR TA GD SL P ASTT G AL L SLA DRLD N L L G C F AL G LK P T S SS D 791
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 835 P FG LRR ISY G LVQI L VENKKNF DL TKA L TLV A EEQ P --- ITIDSG V I DEV VQ FV TR RL EQL L V D E G INCEIVRS VL IERA 911
Cdd:PRK14908 792 P YA LRR QAL G VLTL L RATPASL DL EDL L ARL A RHF P stt VWVKEA V L DEV LE FV WG RL KTQ L L D L G FDKDEIAA VL PDAC 871
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 912 NC P YL A SQ TA IEMEAFSR TE D F PK I VE A YS R PT RI IRG kei G S ALEV DAS VFEKDE E RA L wsay LEVA D KIHPGV ----- 986
Cdd:PRK14908 872 KN P AE A DK TA QALQELKS TE I F AE I AA A LN R LK RI LAS --- L S FSVT DAS LLLEPA E LN L ---- KQAL D AFREEL telpi 944
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
8H1C_B 987 D I K AFAD A SL EL L Q PLED FF TN V F VMA E DE KV RN N RL A LL TKVAS L PK G IA D LSV L 1042
Cdd:PRK14908 945 D L K DYVA A AA EL P Q AVNT FF DE V L VMA D DE AI RN A RL G LL AAIRD L KF G VL D WDA L 1000
GlyS
COG0751 Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; ...
361-1042
0e+00
Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; Glycyl-tRNA synthetase, beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440514 [Multi-domain]
Cd Length: 690
Bit Score: 796.22
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 361 RAFV LEIGTEELP PHDVIEATK QL EKS L IQI L EKR RLS H G K V RS Y G TPRRLAV V VE N L NM KQ MEE E I E LR GPPV AK AFD Q 440
Cdd:COG0751 3 KDLL LEIGTEELP AKFLPKLLE QL AEL L AAG L KEA RLS F G E V EV Y A TPRRLAV L VE G L AE KQ PDR E E E VK GPPV KA AFD A 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 441 E G R PTKAA E GF C R KNN V PI D S L Y RR TDG K T EY IY AR VKESA R FAD E V L T E D LP TI I SGIS FPKSMRW - NSNIV F S RP I RW 519
Cdd:COG0751 83 D G N PTKAA L GF A R SQG V DV D D L E RR ETD K G EY LF AR KTIKG R PTA E L L P E I LP EA I AKLP FPKSMRW g DGDVR F V RP V RW 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 520 IF AL H GD LI VPF CFA G IS SG NQSC G L R NSSLANFKVEA A EL Y LH TL EKAGILI D MQ ER KQR I LHDSSIL A EGV GG DIIAP 599
Cdd:COG0751 163 LV AL L GD EV VPF EIL G LK SG RTTR G H R FLGPGPIEIAS A DD Y EE TL REGYVIA D FE ER REL I REQLEAA A AEL GG TADID 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 600 DS L VQ EV I NLVE A P MPII G RY D VS FL A LP KD VLIT V M QK HQ K YFPV TSKT m G N LLP C FITV A NG AI K E - E V V RK GNE A VL 678
Cdd:COG0751 243 ED L LD EV T NLVE W P TALL G SF D EE FL E LP QE VLIT T M KE HQ R YFPV LDAD - G K LLP Y FITV S NG ES K D p E N V IA GNE R VL 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 679 RAR YE DAKFFY KM D TQ K K L SEFRDQ L SSIL F H E R LGT ML DK MK R V E NTV A EV A LL LG IN E K m IPAIKD AA A LA MS DL A T N 758
Cdd:COG0751 322 RAR LA DAKFFY EE D LK K P L EDRVEK L KKVV F Q E K LGT LA DK VE R I E ALA A AI A EQ LG LD E E - AALAER AA L LA KA DL V T Q 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 759 I V T EF TS L A GIM A R H YAL R DG LS E QI A E A LF E IT LPRF S GD VF P K T DP G IVL A VT D R LD S LVG L FG A G CQ P SSTN DPF G L 838
Cdd:COG0751 401 M V G EF PE L Q GIM G R Y YAL H DG EP E EV A L A IE E HY LPRF A GD AL P S T LV G AIV A LA D K LD T LVG I FG I G LI P TGSK DPF A L 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 839 RR ISY G LVQ IL V E NKKNF DL TKA L TLVAEEQPITI D S - G V ID EV VQ F VTR RL EQ LL VD EGI NCEI V RS VL IERANC P YL A 917
Cdd:COG0751 481 RR AAL G ILR IL I E KGLPL DL SEL L DAALALYGEQL D A e E V VE EV LD F FLE RL RN LL QE EGI SYDV V DA VL ALGPDD P LD A 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 918 SQT A IEME AF SRTED F PKIVE A YS R PTR I IRGK E IGSAL EVD ASVF E KDE E R AL WS A YL E VADKIHPGVDIKAFAD A s L E 997
Cdd:COG0751 561 DAR A KALA AF RALPE F EALAA A NK R VAN I LKKA E GEVSA EVD PALL E EPA E K AL YE A LE E LEPEVEALLAAGDYEE A - L A 639
650 660 670 680
....*....|....*....|....*....|....*....|....*....
8H1C_B 998 L L ---- Q P LED FF T NV F VMAEDE KV R N NRLALL TKVAS L PKGI AD L S V L 1042
Cdd:COG0751 640 A L aalr P P VDA FF D NV M VMAEDE AL R A NRLALL ARLRA L FLRV AD I S K L 688
tRNA_synt_2f
pfam02092 Glycyl-tRNA synthetase beta subunit;
363-907
0e+00
Glycyl-tRNA synthetase beta subunit;
Pssm-ID: 460442
Cd Length: 536
Bit Score: 700.31
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 363 FV LEIGTEELP PHDVIE A TK QL EKSLIQI L EKR RLS H G K V RSYG TPRRLAV V VE N L NM KQ MEE E I E LR GPPV AK AFD QE G 442
Cdd:pfam02092 1 LL LEIGTEELP ARFLPK A LE QL AELITKL L KEA RLS Y G E V KVFA TPRRLAV L VE G L AE KQ PDR E E E VK GPPV KA AFD AD G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 443 R PTKAAEGF C R KNN V PIDS L YR R TD g K T EY IY AR VK E SA R FAD E V L T E D LP TI I SGIS FPKSMRW - NSNIV F S RPIRW IF 521
Cdd:pfam02092 81 N PTKAAEGF A R SQG V SVED L EI R EK - K G EY LF AR KT E PG R PTA E L L P E I LP EA I ASLP FPKSMRW g DGDLR F V RPIRW LV 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 522 AL H GD LI VPF CFA GI S SG NQSC G L R NSSLANFKVEA A EL Y LHT L EK A GILI D MQ ER KQR IL HDSSI LA EGV GG DIIAPDS 601
Cdd:pfam02092 160 AL L GD EV VPF EIL GI K SG RTTR G H R FLGPGPIEIAS A DD Y EEK L RE A FVIA D PE ER REI IL EQIEA LA AEA GG TVDIDED 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 602 L VQ EV I NLVE A P MPII G RY D VS FL A LP KD VLIT V M QK HQ K YFPV TSKT m G N LLP C FITV A NG AIK - E E V V RK GNE A VLRA 680
Cdd:pfam02092 240 L LD EV T NLVE Y P TALL G SF D EE FL E LP EE VLIT S M KE HQ R YFPV RDAD - G K LLP Y FITV S NG DPD d P E N V IA GNE R VLRA 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 681 R YE DAKFFY KM D TQ K K L SEFRDQ L SSIL F H E R LGT ML DK MK R V E NTV A EV A LL LG inekmip AIKD AA A LA MS DL A T NI V 760
Cdd:pfam02092 319 R LA DAKFFY EE D LK K P L ESRVEK L KKVV F Q E K LGT LA DK VE R I E ALA A YL A EQ LG ------- DAER AA L LA KA DL V T EM V 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 761 T EF TS L A GIM A R H YAL R DG LS E QI A E A LF E IT LPRF S GD VF P K T DP G I V L A VT D R LD S LVG L FG A G CQ P SSTN DPF G LRR 840
Cdd:pfam02092 392 G EF PE L Q GIM G R Y YAL A DG ED E EV A L A IE E HY LPRF A GD AL P S T LV G A V V A LA D K LD T LVG I FG I G LI P TGSK DPF A LRR 471
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8H1C_B 841 ISY G LVQ IL V E NKKNF DL TKA L TLVA E EQP iti D SG V IDEVVQ F VTR RL EQ LL VD EGI NCEI V RS VL 907
Cdd:pfam02092 472 AAL G IIR IL L E KGLDL DL REL L EKAL E LYG --- D EE V LADLLE F FLD RL KN LL RE EGI RYDV V DA VL 535
GlyRS_alpha_core
cd00733 Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions ...
50-328
0e+00
Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the attachment of glycine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. This alignment contains only sequences from the GlyRS form which heterotetramerizes. The homodimer form of GlyRS is in a different family of class II aaRS. Class II assignment is based upon structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238375
Cd Length: 279
Bit Score: 573.52
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 50 TFQ QA I QR LQ DY WAS V GC AVM Q CSNT EVGAGT MN P L TFLR V LGPEPWNVAYVEPS I RP D D S RYG D NPNRLQ RHT QFQVI L 129
Cdd:cd00733 1 TFQ DL I LK LQ KF WAS Q GC LII Q PYDM EVGAGT FH P A TFLR A LGPEPWNVAYVEPS R RP T D G RYG E NPNRLQ HYY QFQVI I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 130 KP D P G N S Q D L F L H SL S ALGIN VR EHDIRFVEDNWESP V LGAWGLGWEVW M DGME I TQFTYFQQ S G SL P LL P V SVEITYGL 209
Cdd:cd00733 81 KP S P D N I Q E L Y L E SL E ALGIN PK EHDIRFVEDNWESP T LGAWGLGWEVW L DGME V TQFTYFQQ V G GI P CK P I SVEITYGL 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 210 ERI L M S LQGVD HFKN I QYT K G ITYG EL FL E NE K E M S A Y YL E H ANVD NIQKH F D D F E E EA RS LL S L W LP I PAYD H VLK A SH 289
Cdd:cd00733 161 ERI A M Y LQGVD NVYD I EWN K K ITYG DV FL Q NE I E Q S V Y NF E Y ANVD MLFQL F E D Y E K EA KR LL E L G LP L PAYD Y VLK C SH 240
250 260 270
....*....|....*....|....*....|....*....
8H1C_B 290 A FN I LD S RG FVG VTER A RY FG R M R S LAR QC A Q L W V KT RE 328
Cdd:cd00733 241 T FN L LD A RG AIS VTER Q RY IL R I R N LAR EI A K L Y V EQ RE 279
glyS
TIGR00211 glycyl-tRNA synthetase, tetrameric type, beta subunit; The glycyl-tRNA synthetases differ even ...
363-1042
0e+00
glycyl-tRNA synthetase, tetrameric type, beta subunit; The glycyl-tRNA synthetases differ even among the eubacteria in oligomeric structure. In Escherichia coli and most others, it is a heterodimer of two alpha chains and two beta chains, encoded by tandem genes. The genes are similar, but fused, in Chlamydia trachomatis. By contrast, the glycyl-tRNA synthetases of Thermus thermophilus and of archaea and eukaryotes differ considerably; they are homodimeric, mutually similar, and not detected by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272962 [Multi-domain]
Cd Length: 691
Bit Score: 547.09
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 363 F VL EIGTEELP PHDVIEATK Q LEKS L IQI L E K RR L S HG K V RSYG TPRRLAV V V EN L NMK Q MEEEI E LR GP P V AK AFD QE G 442
Cdd:TIGR00211 6 F LV EIGTEELP AKALRSLAT Q FADK L TAE L N K AG L E HG N V EIFA TPRRLAV L V KD L AEL Q PDRKE E KK GP A V KI AFD AD G 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 443 R PTKAA E GF CRKNNVPIDSLYRRTDG K T E YIYA R VKESARFADEV L TEDLPTIISGIS FPKSMRW - N SNIV F S RPI R WI F 521
Cdd:TIGR00211 86 K PTKAA L GF AKGQGINVEDAEIFQTD K G E WLFV R KIHEGQPTKDL L PPLVLEFLAKLP FPKSMRW g N VDVR F I RPI H WI V 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 522 A L H GD LIV P FCFAGIS S GNQSC G L R NSSLANFKV E AAEL Y LHT L EKAGILI D MQ ERK QR IL HDSSI LA EGV GG DIIAPDS 601
Cdd:TIGR00211 166 V L L GD DVI P IEILNVK S DRTTR G H R FLGEDEVSI E SPDA Y PEQ L KENHVIA D PK ERK AM IL QQIET LA AKL GG IADIDED 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 602 L VQ EV IN LVE A P MPII G RYDVS FL A LP KD VL I T V M QK HQ K YFPV TS K T m G N LLP C FITV A NG AI K E - EVVRK GNE A VLRA 680
Cdd:TIGR00211 246 L LD EV VS LVE Y P TALL G KFEEE FL S LP AE VL V T T M KE HQ R YFPV YD K D - G K LLP H FITV S NG NS K D p QKIIL GNE K VLRA 324
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 681 R YE DA K FFYK M D TQ K K L SEFRDQ L SSIL F HER LGT ML DK MK R VENTVAEV A LL LG IN E K M IPAI K D AA A L AMS DL A TN I V 760
Cdd:TIGR00211 325 R LS DA E FFYK T D LK K P L DDNLPR L ETVV F QQE LGT LK DK VD R ISIIAGYI A QQ LG AD E N M LEHV K R AA L L SKA DL V TN M V 404
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 761 T EF TS L A GIM ARH YA LR DG LS E QI A E A LF E IT LPR FS GD VF P KTDP G I V L A VT D R LD S L VGL FG A G CQ P SSTN DPF G LRR 840
Cdd:TIGR00211 405 Y EF PE L Q GIM GEK YA RH DG ED E AV A V A VN E QY LPR SA GD DL P SSLV G S V V A MA D K LD T L ASI FG I G QI P TGSK DPF A LRR 484
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 841 ISY G LVQ I L VE NKKNF DL TKA LT LVAEE Q PI - TID S G V IDEVVQ F VTR R LEQ LL V DEGI NCEIVRS VL IE R ANC P YLASQ 919
Cdd:TIGR00211 485 AAL G VLR I I VE KNLEI DL EEL LT NFVLL Q GD k LTN S N V LEDLED F FLQ R FRA LL Q DEGI DVDVIQA VL AR R ETD P ADFDA 564
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 920 T A IEMEA F SRTEDFPKIVE A YS R PTR I IRGKEIGSAL E VD A SV F EKDE E R AL WS A Y L EVADKIHPGV --- D IKAFAD A SL 996
Cdd:TIGR00211 565 R A QALSH F RDLPKAEALAA A NK R VAN I LKKGNPVLSS E IQ A NL F KEPK E K AL FE A V L AIKMNAQESF esg D YETALE A LA 644
650 660 670 680
....*....|....*....|....*....|....*....|....*.
8H1C_B 997 EL LQ P LED FF TN V F VMA E D EKV R N NRL AL L TKVAS L PKGI AD L S V L 1042
Cdd:TIGR00211 645 EL RA P VDE FF DS V M VMA D D IEL R Q NRL NF L WGLRQ L FLEV AD I S A L 690
Name
Accession
Description
Interval
E-value
PRK14908
PRK14908 glycine--tRNA ligase;
45-1042
0e+00
glycine--tRNA ligase;
Pssm-ID: 237859 [Multi-domain]
Cd Length: 1000
Bit Score: 1185.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 45 SS SV LT F Q QAIQR L QD YW ASV GC AVM Q CSNT EVGAGT M NP L TFLRVLGPEPW N VAYVEPS I RPDD S RYG D NPNRLQ RH TQ 124
Cdd:PRK14908 1 SS QP LT M Q DMLLA L LR YW SEQ GC IIH Q GYDL EVGAGT F NP A TFLRVLGPEPW R VAYVEPS R RPDD G RYG Q NPNRLQ TY TQ 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 125 FQVILKP D PGN S Q D L F L H SL S A L GI NV R E HDIRFV E D N WE S P VL GAWGLGWEVW M DGMEITQFTYFQQ S G SL PL L P V S V E 204
Cdd:PRK14908 81 FQVILKP V PGN P Q E L Y L E SL K A I GI DL R D HDIRFV H D D WE N P TI GAWGLGWEVW L DGMEITQFTYFQQ A G GK PL D P I S G E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 205 ITYG L ERI L M S LQ G V D HFK N I QYTK G I TYGE L F LEN E K EMS A Y YLEH AN VDNIQ KHF D D FEE EA RS LL SLW LP I PAYD H V 284
Cdd:PRK14908 161 ITYG I ERI A M Y LQ K V N HFK D I AWND G L TYGE I F QQA E Y EMS R Y NFDD AN TEMWL KHF E D YAA EA LR LL DAG LP V PAYD F V 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 285 LKASHAFNILD S RG FVG VTER A RY FG R M R S LAR QC A Q L W V KT RE N LG Y PL GT yqesn LIY P HVSEK P SRKGVVGQ P RAFV 364
Cdd:PRK14908 241 LKASHAFNILD A RG AIS VTER T RY IA R I R Q LAR AV A D L Y V EW RE E LG F PL LK ----- VPP P PAAVT P KKTPDICG P ETLL 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 365 L EIG T EELP PHD V IEATK QLE KS L IQI L EKR RL SHG K VRSY GTPRRLA VV VE NLNMKQMEE E I E L RGP PVAK AFD QE G R P 444
Cdd:PRK14908 316 F EIG S EELP ATF V PIGIQ QLE SA L REL L ADT RL GYE K LEVL GTPRRLA LL VE DVAPREPDA E R E K RGP RLSA AFD AD G T P 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 445 T K A A EGF C R KNN V P I DS L --------- YR R TDGKT EY IYARVK E SA R F A DEV L TED LP TI I SGIS FPK S MRW N - SNIVFS 514
Cdd:PRK14908 396 T P A G EGF F R SQG V D I SH L saldqdgai EI R EINGV EY LFLVRP E PG R D A AAI L ANE LP EL I QSLR FPK K MRW D d PGLSYA 475
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 515 RPIRW IF AL H GD L IVP FCFAGIS SG NQSC G L R NSSLANFKVEA A EL Y LH TL EK A GILIDMQ ER KQR I LHDSSI LA EG V GG 594
Cdd:PRK14908 476 RPIRW LV AL Y GD Q IVP ISVGTLA SG RTTR G H R QLDPPPVEIPS A DG Y VE TL RQ A CVILSPK ER REI I VQGLQN LA AD V QI 555
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 595 D I IA PDS L VQ EV I NLVE A P MP I I G RY D VS FL A LPK DV LI TV M Q KHQ K YFPV TS k TM G N LL PC F IT VA N G AIKE E V VR k GN 674
Cdd:PRK14908 556 D A IA EPR L ID EV T NLVE H P FV I L G QF D EK FL E LPK EL LI AE M V KHQ R YFPV RD - AQ G T LL NH F VI VA D G SPDD E I VR - GN 633
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 675 E A VLRAR YE D AK F FY K M D TQKK L SE F RDQ L S S ILFH E R LG TML DK MK R VENTVA E V A L LL GINEKM ip AIKD AA A L AMS D 754
Cdd:PRK14908 634 E K VLRAR LT D GA F LF K A D LKTP L ET F VEK L K S VTYF E A LG SLA DK VE R IKAHAE E L A A LL PLSARE -- TLDR AA E L CKF D 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 755 L ATNI V T EF TS L A GIM A R H YA L R D G LS E QI A E AL F E IT LPR FS GD VF P KTDP G IV L AVT DRLD S L V G L F GA G CQ P S S TN D 834
Cdd:PRK14908 712 L VSQM V N EF PE L Q GIM G R Y YA Q R A G EP E AV A Q AL G E HE LPR TA GD SL P ASTT G AL L SLA DRLD N L L G C F AL G LK P T S SS D 791
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 835 P FG LRR ISY G LVQI L VENKKNF DL TKA L TLV A EEQ P --- ITIDSG V I DEV VQ FV TR RL EQL L V D E G INCEIVRS VL IERA 911
Cdd:PRK14908 792 P YA LRR QAL G VLTL L RATPASL DL EDL L ARL A RHF P stt VWVKEA V L DEV LE FV WG RL KTQ L L D L G FDKDEIAA VL PDAC 871
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 912 NC P YL A SQ TA IEMEAFSR TE D F PK I VE A YS R PT RI IRG kei G S ALEV DAS VFEKDE E RA L wsay LEVA D KIHPGV ----- 986
Cdd:PRK14908 872 KN P AE A DK TA QALQELKS TE I F AE I AA A LN R LK RI LAS --- L S FSVT DAS LLLEPA E LN L ---- KQAL D AFREEL telpi 944
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
8H1C_B 987 D I K AFAD A SL EL L Q PLED FF TN V F VMA E DE KV RN N RL A LL TKVAS L PK G IA D LSV L 1042
Cdd:PRK14908 945 D L K DYVA A AA EL P Q AVNT FF DE V L VMA D DE AI RN A RL G LL AAIRD L KF G VL D WDA L 1000
GlyS
COG0751 Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; ...
361-1042
0e+00
Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; Glycyl-tRNA synthetase, beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440514 [Multi-domain]
Cd Length: 690
Bit Score: 796.22
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 361 RAFV LEIGTEELP PHDVIEATK QL EKS L IQI L EKR RLS H G K V RS Y G TPRRLAV V VE N L NM KQ MEE E I E LR GPPV AK AFD Q 440
Cdd:COG0751 3 KDLL LEIGTEELP AKFLPKLLE QL AEL L AAG L KEA RLS F G E V EV Y A TPRRLAV L VE G L AE KQ PDR E E E VK GPPV KA AFD A 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 441 E G R PTKAA E GF C R KNN V PI D S L Y RR TDG K T EY IY AR VKESA R FAD E V L T E D LP TI I SGIS FPKSMRW - NSNIV F S RP I RW 519
Cdd:COG0751 83 D G N PTKAA L GF A R SQG V DV D D L E RR ETD K G EY LF AR KTIKG R PTA E L L P E I LP EA I AKLP FPKSMRW g DGDVR F V RP V RW 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 520 IF AL H GD LI VPF CFA G IS SG NQSC G L R NSSLANFKVEA A EL Y LH TL EKAGILI D MQ ER KQR I LHDSSIL A EGV GG DIIAP 599
Cdd:COG0751 163 LV AL L GD EV VPF EIL G LK SG RTTR G H R FLGPGPIEIAS A DD Y EE TL REGYVIA D FE ER REL I REQLEAA A AEL GG TADID 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 600 DS L VQ EV I NLVE A P MPII G RY D VS FL A LP KD VLIT V M QK HQ K YFPV TSKT m G N LLP C FITV A NG AI K E - E V V RK GNE A VL 678
Cdd:COG0751 243 ED L LD EV T NLVE W P TALL G SF D EE FL E LP QE VLIT T M KE HQ R YFPV LDAD - G K LLP Y FITV S NG ES K D p E N V IA GNE R VL 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 679 RAR YE DAKFFY KM D TQ K K L SEFRDQ L SSIL F H E R LGT ML DK MK R V E NTV A EV A LL LG IN E K m IPAIKD AA A LA MS DL A T N 758
Cdd:COG0751 322 RAR LA DAKFFY EE D LK K P L EDRVEK L KKVV F Q E K LGT LA DK VE R I E ALA A AI A EQ LG LD E E - AALAER AA L LA KA DL V T Q 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 759 I V T EF TS L A GIM A R H YAL R DG LS E QI A E A LF E IT LPRF S GD VF P K T DP G IVL A VT D R LD S LVG L FG A G CQ P SSTN DPF G L 838
Cdd:COG0751 401 M V G EF PE L Q GIM G R Y YAL H DG EP E EV A L A IE E HY LPRF A GD AL P S T LV G AIV A LA D K LD T LVG I FG I G LI P TGSK DPF A L 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 839 RR ISY G LVQ IL V E NKKNF DL TKA L TLVAEEQPITI D S - G V ID EV VQ F VTR RL EQ LL VD EGI NCEI V RS VL IERANC P YL A 917
Cdd:COG0751 481 RR AAL G ILR IL I E KGLPL DL SEL L DAALALYGEQL D A e E V VE EV LD F FLE RL RN LL QE EGI SYDV V DA VL ALGPDD P LD A 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 918 SQT A IEME AF SRTED F PKIVE A YS R PTR I IRGK E IGSAL EVD ASVF E KDE E R AL WS A YL E VADKIHPGVDIKAFAD A s L E 997
Cdd:COG0751 561 DAR A KALA AF RALPE F EALAA A NK R VAN I LKKA E GEVSA EVD PALL E EPA E K AL YE A LE E LEPEVEALLAAGDYEE A - L A 639
650 660 670 680
....*....|....*....|....*....|....*....|....*....
8H1C_B 998 L L ---- Q P LED FF T NV F VMAEDE KV R N NRLALL TKVAS L PKGI AD L S V L 1042
Cdd:COG0751 640 A L aalr P P VDA FF D NV M VMAEDE AL R A NRLALL ARLRA L FLRV AD I S K L 688
tRNA_synt_2f
pfam02092 Glycyl-tRNA synthetase beta subunit;
363-907
0e+00
Glycyl-tRNA synthetase beta subunit;
Pssm-ID: 460442
Cd Length: 536
Bit Score: 700.31
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 363 FV LEIGTEELP PHDVIE A TK QL EKSLIQI L EKR RLS H G K V RSYG TPRRLAV V VE N L NM KQ MEE E I E LR GPPV AK AFD QE G 442
Cdd:pfam02092 1 LL LEIGTEELP ARFLPK A LE QL AELITKL L KEA RLS Y G E V KVFA TPRRLAV L VE G L AE KQ PDR E E E VK GPPV KA AFD AD G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 443 R PTKAAEGF C R KNN V PIDS L YR R TD g K T EY IY AR VK E SA R FAD E V L T E D LP TI I SGIS FPKSMRW - NSNIV F S RPIRW IF 521
Cdd:pfam02092 81 N PTKAAEGF A R SQG V SVED L EI R EK - K G EY LF AR KT E PG R PTA E L L P E I LP EA I ASLP FPKSMRW g DGDLR F V RPIRW LV 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 522 AL H GD LI VPF CFA GI S SG NQSC G L R NSSLANFKVEA A EL Y LHT L EK A GILI D MQ ER KQR IL HDSSI LA EGV GG DIIAPDS 601
Cdd:pfam02092 160 AL L GD EV VPF EIL GI K SG RTTR G H R FLGPGPIEIAS A DD Y EEK L RE A FVIA D PE ER REI IL EQIEA LA AEA GG TVDIDED 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 602 L VQ EV I NLVE A P MPII G RY D VS FL A LP KD VLIT V M QK HQ K YFPV TSKT m G N LLP C FITV A NG AIK - E E V V RK GNE A VLRA 680
Cdd:pfam02092 240 L LD EV T NLVE Y P TALL G SF D EE FL E LP EE VLIT S M KE HQ R YFPV RDAD - G K LLP Y FITV S NG DPD d P E N V IA GNE R VLRA 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 681 R YE DAKFFY KM D TQ K K L SEFRDQ L SSIL F H E R LGT ML DK MK R V E NTV A EV A LL LG inekmip AIKD AA A LA MS DL A T NI V 760
Cdd:pfam02092 319 R LA DAKFFY EE D LK K P L ESRVEK L KKVV F Q E K LGT LA DK VE R I E ALA A YL A EQ LG ------- DAER AA L LA KA DL V T EM V 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 761 T EF TS L A GIM A R H YAL R DG LS E QI A E A LF E IT LPRF S GD VF P K T DP G I V L A VT D R LD S LVG L FG A G CQ P SSTN DPF G LRR 840
Cdd:pfam02092 392 G EF PE L Q GIM G R Y YAL A DG ED E EV A L A IE E HY LPRF A GD AL P S T LV G A V V A LA D K LD T LVG I FG I G LI P TGSK DPF A LRR 471
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8H1C_B 841 ISY G LVQ IL V E NKKNF DL TKA L TLVA E EQP iti D SG V IDEVVQ F VTR RL EQ LL VD EGI NCEI V RS VL 907
Cdd:pfam02092 472 AAL G IIR IL L E KGLDL DL REL L EKAL E LYG --- D EE V LADLLE F FLD RL KN LL RE EGI RYDV V DA VL 535
GlyQ
COG0752 Glycyl-tRNA synthetase, alpha subunit [Translation, ribosomal structure and biogenesis]; ...
49-331
0e+00
Glycyl-tRNA synthetase, alpha subunit [Translation, ribosomal structure and biogenesis]; Glycyl-tRNA synthetase, alpha subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440515
Cd Length: 283
Bit Score: 586.28
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 49 L TFQ QA I QR LQ D YWA SV GC AVM Q CSNT EVGAGT MN P L TFLR V LGPEPWNVAYV E PS I RP D D S RYG D NPNRLQ RHT QFQVI 128
Cdd:COG0752 1 M TFQ DI I LT LQ K YWA EQ GC VIL Q PYDM EVGAGT FH P A TFLR A LGPEPWNVAYV Q PS R RP T D G RYG E NPNRLQ HYY QFQVI 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 129 LKP D P G N S Q D L F L H SL S ALGI NVR EHDIRFVEDNWESP V LGAWGLGWEVW M DGMEITQFTYFQQ S G SLPLL PVS V EITYG 208
Cdd:COG0752 81 LKP S P D N I Q E L Y L G SL E ALGI DPK EHDIRFVEDNWESP T LGAWGLGWEVW L DGMEITQFTYFQQ V G GIDCD PVS G EITYG 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 209 LER IL M S LQGVD HFKNIQYTK G I TYG EL FL E NE K E M SAY YL E H A N V DNIQKH FDD F E E EA RS LL SLW LP I PAYD H VLKAS 288
Cdd:COG0752 161 LER LA M Y LQGVD NVYDLVWND G V TYG DV FL Q NE V E Q SAY NF E Y A D V EMLFRL FDD Y E A EA KR LL EAG LP L PAYD Y VLKAS 240
250 260 270 280
....*....|....*....|....*....|....*....|...
8H1C_B 289 H A FN I LD S RG FVG VTERA R Y FG R M R S LAR QC A QLWVKT RE N LG 331
Cdd:COG0752 241 H T FN L LD A RG AIS VTERA S Y IL R V R N LAR AV A EAYLEQ RE E LG 283
GlyRS_alpha_core
cd00733 Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions ...
50-328
0e+00
Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the attachment of glycine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. This alignment contains only sequences from the GlyRS form which heterotetramerizes. The homodimer form of GlyRS is in a different family of class II aaRS. Class II assignment is based upon structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238375
Cd Length: 279
Bit Score: 573.52
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 50 TFQ QA I QR LQ DY WAS V GC AVM Q CSNT EVGAGT MN P L TFLR V LGPEPWNVAYVEPS I RP D D S RYG D NPNRLQ RHT QFQVI L 129
Cdd:cd00733 1 TFQ DL I LK LQ KF WAS Q GC LII Q PYDM EVGAGT FH P A TFLR A LGPEPWNVAYVEPS R RP T D G RYG E NPNRLQ HYY QFQVI I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 130 KP D P G N S Q D L F L H SL S ALGIN VR EHDIRFVEDNWESP V LGAWGLGWEVW M DGME I TQFTYFQQ S G SL P LL P V SVEITYGL 209
Cdd:cd00733 81 KP S P D N I Q E L Y L E SL E ALGIN PK EHDIRFVEDNWESP T LGAWGLGWEVW L DGME V TQFTYFQQ V G GI P CK P I SVEITYGL 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 210 ERI L M S LQGVD HFKN I QYT K G ITYG EL FL E NE K E M S A Y YL E H ANVD NIQKH F D D F E E EA RS LL S L W LP I PAYD H VLK A SH 289
Cdd:cd00733 161 ERI A M Y LQGVD NVYD I EWN K K ITYG DV FL Q NE I E Q S V Y NF E Y ANVD MLFQL F E D Y E K EA KR LL E L G LP L PAYD Y VLK C SH 240
250 260 270
....*....|....*....|....*....|....*....
8H1C_B 290 A FN I LD S RG FVG VTER A RY FG R M R S LAR QC A Q L W V KT RE 328
Cdd:cd00733 241 T FN L LD A RG AIS VTER Q RY IL R I R N LAR EI A K L Y V EQ RE 279
tRNA-synt_2e
pfam02091 Glycyl-tRNA synthetase alpha subunit;
51-326
0e+00
Glycyl-tRNA synthetase alpha subunit;
Pssm-ID: 426595
Cd Length: 276
Bit Score: 571.71
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 51 FQ QA I QR LQ DY WA SV GC AVM Q CSNT EVGAGT MN P L TFLR V LGPEPWNVAYV E PS I RP D D S RYG D NPNRLQ RHT QFQVILK 130
Cdd:pfam02091 1 FQ DI I LT LQ KF WA KQ GC VIL Q PYDI EVGAGT FH P A TFLR A LGPEPWNVAYV Q PS R RP T D G RYG E NPNRLQ HYY QFQVILK 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 131 P D P G N S Q D L F L H SL S ALGI NVR EHDIRFVEDNWESP V LGAWGLGWEVW M DGMEITQFTYFQQ S G SLPLL PVSVEITYGLE 210
Cdd:pfam02091 81 P S P D N I Q E L Y L E SL E ALGI DPK EHDIRFVEDNWESP T LGAWGLGWEVW L DGMEITQFTYFQQ V G GIDCK PVSVEITYGLE 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 211 RI L M S LQGVD HFKNIQYTK G I TYG EL FL E NE K E M S A Y YL EHA N V DNIQ K H FDD F E E EA RS LL SLW LP I PAYD H VLK A SH A 290
Cdd:pfam02091 161 RI A M Y LQGVD NVYDLVWND G V TYG DV FL Q NE V E Q S K Y NF EHA D V EMLF K L FDD Y E K EA KR LL EKG LP L PAYD Y VLK C SH T 240
250 260 270
....*....|....*....|....*....|....*.
8H1C_B 291 FN I LD S RG FVG VTERA R Y F GR M R S LAR Q CA QLWVKT 326
Cdd:pfam02091 241 FN L LD A RG AIS VTERA S Y I GR V R N LAR A CA EAYLEQ 276
glyQ
PRK09348 glycyl-tRNA synthetase subunit alpha; Validated
46-328
0e+00
glycyl-tRNA synthetase subunit alpha; Validated
Pssm-ID: 236473
Cd Length: 283
Bit Score: 549.33
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 46 S SVL TFQ QA I QR LQDYWA SV GC AVM Q CSNT EVGAGT MN P L TFLR V LGPEPWN V AYV E PS I RP D D S RYG D NPNRLQ RHT QF 125
Cdd:PRK09348 1 S KKM TFQ DI I LT LQDYWA DQ GC VIL Q PYDM EVGAGT FH P A TFLR A LGPEPWN A AYV Q PS R RP T D G RYG E NPNRLQ HYY QF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 126 QVILKP D P G N S Q D L F L H SL S ALGI NVR EHDIRFVEDNWESP V LGAWGLGWEVW M DGME I TQFTYFQQ S G SLPLL PV SV EI 205
Cdd:PRK09348 81 QVILKP S P D N I Q E L Y L G SL E ALGI DPL EHDIRFVEDNWESP T LGAWGLGWEVW L DGME V TQFTYFQQ V G GIECK PV TG EI 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 206 TYGLER IL M S LQGVD HFKNIQYTK G I TYG EL FL E NE K E M S A Y YL EHA N V DNIQ K H FDD F E E EA RS LL SLW LP I PAYD H VL 285
Cdd:PRK09348 161 TYGLER LA M Y LQGVD NVYDLVWND G V TYG DV FL Q NE V E Q S K Y NF EHA D V EMLF K L FDD Y E K EA KR LL EKG LP L PAYD Y VL 240
250 260 270 280
....*....|....*....|....*....|....*....|...
8H1C_B 286 KASH A FN I LD S RG FVG VTER A RY FG R M R S LAR QC A QLWVKT RE 328
Cdd:PRK09348 241 KASH T FN L LD A RG AIS VTER Q RY IL R I R N LAR AV A EAYLES RE 283
glyS
TIGR00211 glycyl-tRNA synthetase, tetrameric type, beta subunit; The glycyl-tRNA synthetases differ even ...
363-1042
0e+00
glycyl-tRNA synthetase, tetrameric type, beta subunit; The glycyl-tRNA synthetases differ even among the eubacteria in oligomeric structure. In Escherichia coli and most others, it is a heterodimer of two alpha chains and two beta chains, encoded by tandem genes. The genes are similar, but fused, in Chlamydia trachomatis. By contrast, the glycyl-tRNA synthetases of Thermus thermophilus and of archaea and eukaryotes differ considerably; they are homodimeric, mutually similar, and not detected by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272962 [Multi-domain]
Cd Length: 691
Bit Score: 547.09
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 363 F VL EIGTEELP PHDVIEATK Q LEKS L IQI L E K RR L S HG K V RSYG TPRRLAV V V EN L NMK Q MEEEI E LR GP P V AK AFD QE G 442
Cdd:TIGR00211 6 F LV EIGTEELP AKALRSLAT Q FADK L TAE L N K AG L E HG N V EIFA TPRRLAV L V KD L AEL Q PDRKE E KK GP A V KI AFD AD G 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 443 R PTKAA E GF CRKNNVPIDSLYRRTDG K T E YIYA R VKESARFADEV L TEDLPTIISGIS FPKSMRW - N SNIV F S RPI R WI F 521
Cdd:TIGR00211 86 K PTKAA L GF AKGQGINVEDAEIFQTD K G E WLFV R KIHEGQPTKDL L PPLVLEFLAKLP FPKSMRW g N VDVR F I RPI H WI V 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 522 A L H GD LIV P FCFAGIS S GNQSC G L R NSSLANFKV E AAEL Y LHT L EKAGILI D MQ ERK QR IL HDSSI LA EGV GG DIIAPDS 601
Cdd:TIGR00211 166 V L L GD DVI P IEILNVK S DRTTR G H R FLGEDEVSI E SPDA Y PEQ L KENHVIA D PK ERK AM IL QQIET LA AKL GG IADIDED 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 602 L VQ EV IN LVE A P MPII G RYDVS FL A LP KD VL I T V M QK HQ K YFPV TS K T m G N LLP C FITV A NG AI K E - EVVRK GNE A VLRA 680
Cdd:TIGR00211 246 L LD EV VS LVE Y P TALL G KFEEE FL S LP AE VL V T T M KE HQ R YFPV YD K D - G K LLP H FITV S NG NS K D p QKIIL GNE K VLRA 324
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 681 R YE DA K FFYK M D TQ K K L SEFRDQ L SSIL F HER LGT ML DK MK R VENTVAEV A LL LG IN E K M IPAI K D AA A L AMS DL A TN I V 760
Cdd:TIGR00211 325 R LS DA E FFYK T D LK K P L DDNLPR L ETVV F QQE LGT LK DK VD R ISIIAGYI A QQ LG AD E N M LEHV K R AA L L SKA DL V TN M V 404
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 761 T EF TS L A GIM ARH YA LR DG LS E QI A E A LF E IT LPR FS GD VF P KTDP G I V L A VT D R LD S L VGL FG A G CQ P SSTN DPF G LRR 840
Cdd:TIGR00211 405 Y EF PE L Q GIM GEK YA RH DG ED E AV A V A VN E QY LPR SA GD DL P SSLV G S V V A MA D K LD T L ASI FG I G QI P TGSK DPF A LRR 484
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 841 ISY G LVQ I L VE NKKNF DL TKA LT LVAEE Q PI - TID S G V IDEVVQ F VTR R LEQ LL V DEGI NCEIVRS VL IE R ANC P YLASQ 919
Cdd:TIGR00211 485 AAL G VLR I I VE KNLEI DL EEL LT NFVLL Q GD k LTN S N V LEDLED F FLQ R FRA LL Q DEGI DVDVIQA VL AR R ETD P ADFDA 564
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 920 T A IEMEA F SRTEDFPKIVE A YS R PTR I IRGKEIGSAL E VD A SV F EKDE E R AL WS A Y L EVADKIHPGV --- D IKAFAD A SL 996
Cdd:TIGR00211 565 R A QALSH F RDLPKAEALAA A NK R VAN I LKKGNPVLSS E IQ A NL F KEPK E K AL FE A V L AIKMNAQESF esg D YETALE A LA 644
650 660 670 680
....*....|....*....|....*....|....*....|....*.
8H1C_B 997 EL LQ P LED FF TN V F VMA E D EKV R N NRL AL L TKVAS L PKGI AD L S V L 1042
Cdd:TIGR00211 645 EL RA P VDE FF DS V M VMA D D IEL R Q NRL NF L WGLRQ L FLEV AD I S A L 690
glyQ
TIGR00388 glycyl-tRNA synthetase, tetrameric type, alpha subunit; This tetrameric form of glycyl-tRNA ...
50-334
5.18e-144
glycyl-tRNA synthetase, tetrameric type, alpha subunit; This tetrameric form of glycyl-tRNA synthetase (2 alpha, 2 beta) is found in the majority of completed eubacterial genomes, with the two genes fused in a few species. A substantially different homodimeric form (not recognized by this model) replaces this form in the Archaea, animals, yeasts, and some eubacteria. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 129483
Cd Length: 293
Bit Score: 432.34
E-value: 5.18e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 50 TFQ QA I QR LQ D YWA SV GC AVM Q CSNT E V GAGTM N P L TFLR V LGPEPW N VAYVEPS I RP D D S RYG D NPNRLQ RHT QFQV IL 129
Cdd:TIGR00388 2 TFQ GL I LK LQ E YWA NQ GC LIV Q PYDM E K GAGTM H P M TFLR S LGPEPW A VAYVEPS R RP T D G RYG E NPNRLQ HYY QFQV VI 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 130 KP D P G N S Q D L F L H SL S ALGI NVR EHDIRFVEDNWE S P V LGAWGLGWEVW M DGME I TQFTYFQQ S G S L PLL PVSVEITYGL 209
Cdd:TIGR00388 82 KP S P D N I Q E L Y L D SL R ALGI DPT EHDIRFVEDNWE N P T LGAWGLGWEVW L DGME V TQFTYFQQ V G G L ECK PVSVEITYGL 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 210 ER IL M SL QGV DHFKNIQYTK G ---- I TYG EL F LE NE K E M S A Y YL E H A N VD NIQKH F DDF E E EA RS LL SLW LP I PAY DH VL 285
Cdd:TIGR00388 162 ER LA M YI QGV ENVYDLEWSD G plgk T TYG DV F HQ NE V E Q S T Y NF E T A D VD FLFQL F KQY E K EA QQ LL ENG LP L PAY EY VL 241
250 260 270 280
....*....|....*....|....*....|....*....|....*....
8H1C_B 286 K A SH A FN I LD S R GFVG VTER A RY FG R M R S LA RQC A QLWVKT RE N LG Y PL 334
Cdd:TIGR00388 242 K C SH S FN L LD A R KAIS VTER Q RY IL R I R N LA KGV A EAYYEQ RE A LG F PL 290
class_II_aaRS-like_core
cd00768 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA ...
86-212
4.29e-12
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. These enzymes are usually homodimers. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. The substrate specificity of this reaction is further determined by additional domains. Intererestingly, this domain is also found is asparagine synthase A (AsnA), in the accessory subunit of mitochondrial polymerase gamma and in the bacterial ATP phosphoribosyltransferase regulatory subunit HisZ.
Pssm-ID: 238391 [Multi-domain]
Cd Length: 211
Bit Score: 66.37
E-value: 4.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 86 T F LRVLGPE P WNV A YVE P SI R PDDS R Y G dn PN R LQRH TQ FQVILKPDP G NSQDL F LHS ------- L S ALGI N vre H DI R F 158
Cdd:cd00768 66 L F VSHIRKL P LRL A EIG P AF R NEGG R R G -- LR R VREF TQ LEGEVFGED G EEASE F EEL ielteel L R ALGI K --- L DI V F 140
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
8H1C_B 159 VE DNWESPVL G AW G L G W E VWM D ----- G M EI TQFT Y F Q QSGSLP ------------ LL P VSVEITY GLER I 212
Cdd:cd00768 141 VE KTPGEFSP G GA G P G F E IEV D hpegr G L EI GSGG Y R Q DEQARA adlyfldealey RY P PTIGFGL GLER L 211
DALR_1
pfam05746 DALR anticodon binding domain; This all alpha helical domain is the anticodon binding domain ...
939-1031
3.84e-05
DALR anticodon binding domain; This all alpha helical domain is the anticodon binding domain in Arginyl and glycyl tRNA synthetase. This domain is known as the DALR domain after characteriztic conserved amino acids.
Pssm-ID: 399042 [Multi-domain]
Cd Length: 117
Bit Score: 44.18
E-value: 3.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8H1C_B 939 A YS R PTR I I R - GK E I G SA L EV DA SVFEKD EE RA L WS A Y L E ------- V A DKIH P GV dika F A DASL EL LQPLED F FT N VF 1010
Cdd:pfam05746 4 A HA R ICS I L R k AG E L G IN L DI DA DLLTEE EE KE L LK A L L Q fpevlee A A EELE P HR ---- L A NYLY EL ASAFHS F YN N CR 79
90 100
....*....|....*....|.
8H1C_B 1011 V MA ED EKV RN N RLALL TK V AS 1031
Cdd:pfam05746 80 V LD ED NEE RN A RLALL KA V RQ 100
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
