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Conserved domains on  [gi|11692740|gb|AAG39976|]
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PeiW [Methanothermobacter phage psiM100]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_C71 pfam12386
Pseudomurein endo-isopeptidase Pei; This peptidase has the catalytic triad C-H-D at the ...
 142-283 5.51e-97

Pseudomurein endo-isopeptidase Pei; This peptidase has the catalytic triad C-H-D at the C-terminal end, a triad similar to that in thiol proteases and animal transglutaminases. It catalyzes the in vitro lysis of M. marburgensis cells under reducing conditions and exhibits characteriztics of metal-activated peptidases.


:

Pssm-ID: 403551  Cd Length: 149  Bit Score: 281.54  E-value: 5.51e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11692740   142 SLKGHWTTKVIEKIGTFHDATSLYERVKKTCKYKYYYNDQVPNHVAVMRMTTSGINCTDACQLFSKVLEEMGYEVKIEHV 221
Cdd:pfam12386   1 PLKGEETREMIEKIGEFHDATQLYELVKKRCKYKFYYNDQTPNHEALKKMTTDGINCTDACQLFKKVIEELGYEVKIEHV 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 11692740   222 RVKCNDGKWYGHYLLRVGGFELKD-------GTIWDYVSATKTGRPLGVPCCTAGFQHLGWGIVGPVYD 283
Cdd:pfam12386  81 KVKCNDGKWYGHYFLRVAGFELADvslpserGTIWDYVSATKTGRPLGAPCCSAGFQHLGWGIVGPKHD 149
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 105-137 5.13e-07

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


:

Pssm-ID: 117915  Cd Length: 33  Bit Score: 45.13  E-value: 5.13e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 11692740   105 KSDHVSLGTFKDMLRRYKDFVRINGREPNYISI 137
Cdd:pfam09373   1 GSGKISYEEYLDMASRVLNFIESNGRLPNYVSI 33
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 34-65 1.66e-06

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


:

Pssm-ID: 117915  Cd Length: 33  Bit Score: 43.59  E-value: 1.66e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 11692740    34 GYKVMLPVFKDMLRRYEDFVRINGREPNYISI 65
Cdd:pfam09373   2 SGKISYEEYLDMASRVLNFIESNGRLPNYVSI 33
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 3-31 1.74e-05

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


:

Pssm-ID: 117915  Cd Length: 33  Bit Score: 40.89  E-value: 1.74e-05
                          10        20
                  ....*....|....*....|....*....
gi 11692740     3 VGLNEFLDMKKRYEDFKMKNKREPRYVTT 31
Cdd:pfam09373   5 ISYEEYLDMASRVLNFIESNGRLPNYVSI 33
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 70-100 2.19e-05

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


:

Pssm-ID: 117915  Cd Length: 33  Bit Score: 40.51  E-value: 2.19e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 11692740    70 NGKIEIKKFRDMLRRYEDFVRINGREPNIIY 100
Cdd:pfam09373   2 SGKISYEEYLDMASRVLNFIESNGRLPNYVS 32
 
Name Accession Description Interval E-value
Peptidase_C71 pfam12386
Pseudomurein endo-isopeptidase Pei; This peptidase has the catalytic triad C-H-D at the ...
 142-283 5.51e-97

Pseudomurein endo-isopeptidase Pei; This peptidase has the catalytic triad C-H-D at the C-terminal end, a triad similar to that in thiol proteases and animal transglutaminases. It catalyzes the in vitro lysis of M. marburgensis cells under reducing conditions and exhibits characteriztics of metal-activated peptidases.


Pssm-ID: 403551  Cd Length: 149  Bit Score: 281.54  E-value: 5.51e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11692740   142 SLKGHWTTKVIEKIGTFHDATSLYERVKKTCKYKYYYNDQVPNHVAVMRMTTSGINCTDACQLFSKVLEEMGYEVKIEHV 221
Cdd:pfam12386   1 PLKGEETREMIEKIGEFHDATQLYELVKKRCKYKFYYNDQTPNHEALKKMTTDGINCTDACQLFKKVIEELGYEVKIEHV 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 11692740   222 RVKCNDGKWYGHYLLRVGGFELKD-------GTIWDYVSATKTGRPLGVPCCTAGFQHLGWGIVGPVYD 283
Cdd:pfam12386  81 KVKCNDGKWYGHYFLRVAGFELADvslpserGTIWDYVSATKTGRPLGAPCCSAGFQHLGWGIVGPKHD 149
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 105-137 5.13e-07

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


Pssm-ID: 117915  Cd Length: 33  Bit Score: 45.13  E-value: 5.13e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 11692740   105 KSDHVSLGTFKDMLRRYKDFVRINGREPNYISI 137
Cdd:pfam09373   1 GSGKISYEEYLDMASRVLNFIESNGRLPNYVSI 33
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 34-65 1.66e-06

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


Pssm-ID: 117915  Cd Length: 33  Bit Score: 43.59  E-value: 1.66e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 11692740    34 GYKVMLPVFKDMLRRYEDFVRINGREPNYISI 65
Cdd:pfam09373   2 SGKISYEEYLDMASRVLNFIESNGRLPNYVSI 33
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 3-31 1.74e-05

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


Pssm-ID: 117915  Cd Length: 33  Bit Score: 40.89  E-value: 1.74e-05
                          10        20
                  ....*....|....*....|....*....
gi 11692740     3 VGLNEFLDMKKRYEDFKMKNKREPRYVTT 31
Cdd:pfam09373   5 ISYEEYLDMASRVLNFIESNGRLPNYVSI 33
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 70-100 2.19e-05

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


Pssm-ID: 117915  Cd Length: 33  Bit Score: 40.51  E-value: 2.19e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 11692740    70 NGKIEIKKFRDMLRRYEDFVRINGREPNIIY 100
Cdd:pfam09373   2 SGKISYEEYLDMASRVLNFIESNGRLPNYVS 32
 
Name Accession Description Interval E-value
Peptidase_C71 pfam12386
Pseudomurein endo-isopeptidase Pei; This peptidase has the catalytic triad C-H-D at the ...
 142-283 5.51e-97

Pseudomurein endo-isopeptidase Pei; This peptidase has the catalytic triad C-H-D at the C-terminal end, a triad similar to that in thiol proteases and animal transglutaminases. It catalyzes the in vitro lysis of M. marburgensis cells under reducing conditions and exhibits characteriztics of metal-activated peptidases.


Pssm-ID: 403551  Cd Length: 149  Bit Score: 281.54  E-value: 5.51e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11692740   142 SLKGHWTTKVIEKIGTFHDATSLYERVKKTCKYKYYYNDQVPNHVAVMRMTTSGINCTDACQLFSKVLEEMGYEVKIEHV 221
Cdd:pfam12386   1 PLKGEETREMIEKIGEFHDATQLYELVKKRCKYKFYYNDQTPNHEALKKMTTDGINCTDACQLFKKVIEELGYEVKIEHV 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 11692740   222 RVKCNDGKWYGHYLLRVGGFELKD-------GTIWDYVSATKTGRPLGVPCCTAGFQHLGWGIVGPVYD 283
Cdd:pfam12386  81 KVKCNDGKWYGHYFLRVAGFELADvslpserGTIWDYVSATKTGRPLGAPCCSAGFQHLGWGIVGPKHD 149
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 105-137 5.13e-07

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


Pssm-ID: 117915  Cd Length: 33  Bit Score: 45.13  E-value: 5.13e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 11692740   105 KSDHVSLGTFKDMLRRYKDFVRINGREPNYISI 137
Cdd:pfam09373   1 GSGKISYEEYLDMASRVLNFIESNGRLPNYVSI 33
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 34-65 1.66e-06

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


Pssm-ID: 117915  Cd Length: 33  Bit Score: 43.59  E-value: 1.66e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 11692740    34 GYKVMLPVFKDMLRRYEDFVRINGREPNYISI 65
Cdd:pfam09373   2 SGKISYEEYLDMASRVLNFIESNGRLPNYVSI 33
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 3-31 1.74e-05

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


Pssm-ID: 117915  Cd Length: 33  Bit Score: 40.89  E-value: 1.74e-05
                          10        20
                  ....*....|....*....|....*....
gi 11692740     3 VGLNEFLDMKKRYEDFKMKNKREPRYVTT 31
Cdd:pfam09373   5 ISYEEYLDMASRVLNFIESNGRLPNYVSI 33
PMBR pfam09373
Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic ...
 70-100 2.19e-05

Pseudomurein-binding repeat; Methanothermobacter thermautotrophicus is a methanogenic Gram-positive microorganizm with a cell wall consisting of pseudomurein. This repeat specifically binds to pseudomurein. This repeat is found at the N terminus of PeiW and PeiP which are pseudomurein binding phage proteins.


Pssm-ID: 117915  Cd Length: 33  Bit Score: 40.51  E-value: 2.19e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 11692740    70 NGKIEIKKFRDMLRRYEDFVRINGREPNIIY 100
Cdd:pfam09373   2 SGKISYEEYLDMASRVLNFIESNGRLPNYVS 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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