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gentamicin-3-acetyltransferase [CRIM plasmid pAH143]
GNAT family N-acetyltransferase( domain architecture ID 10456837)
GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Acetyltransf_1 | pfam00583 | Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ... |
40-161 | 4.08e-16 | |||
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. : Pssm-ID: 395465 [Multi-domain] Cd Length: 116 Bit Score: 70.24 E-value: 4.08e-16
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Name | Accession | Description | Interval | E-value | |||
Acetyltransf_1 | pfam00583 | Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ... |
40-161 | 4.08e-16 | |||
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. Pssm-ID: 395465 [Multi-domain] Cd Length: 116 Bit Score: 70.24 E-value: 4.08e-16
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RimI | COG0456 | Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ... |
93-173 | 5.81e-14 | |||
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]; Pssm-ID: 440224 [Multi-domain] Cd Length: 92 Bit Score: 63.91 E-value: 5.81e-14
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NAT_SF | cd04301 | N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ... |
79-144 | 3.17e-09 | |||
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included. Pssm-ID: 173926 [Multi-domain] Cd Length: 65 Bit Score: 50.74 E-value: 3.17e-09
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PRK03624 | PRK03624 | putative acetyltransferase; Provisional |
108-165 | 8.58e-07 | |||
putative acetyltransferase; Provisional Pssm-ID: 235142 [Multi-domain] Cd Length: 140 Bit Score: 46.08 E-value: 8.58e-07
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rimI | TIGR01575 | ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related ... |
89-165 | 7.50e-06 | |||
ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification] Pssm-ID: 273701 [Multi-domain] Cd Length: 131 Bit Score: 43.47 E-value: 7.50e-06
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Name | Accession | Description | Interval | E-value | |||
Acetyltransf_1 | pfam00583 | Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ... |
40-161 | 4.08e-16 | |||
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. Pssm-ID: 395465 [Multi-domain] Cd Length: 116 Bit Score: 70.24 E-value: 4.08e-16
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RimI | COG0456 | Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ... |
93-173 | 5.81e-14 | |||
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]; Pssm-ID: 440224 [Multi-domain] Cd Length: 92 Bit Score: 63.91 E-value: 5.81e-14
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yhbS | COG3153 | Predicted N-acetyltransferase YhbS [General function prediction only]; |
77-161 | 1.45e-11 | |||
Predicted N-acetyltransferase YhbS [General function prediction only]; Pssm-ID: 442387 [Multi-domain] Cd Length: 142 Bit Score: 58.94 E-value: 1.45e-11
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Acetyltransf_7 | pfam13508 | Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions. |
79-161 | 6.19e-10 | |||
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions. Pssm-ID: 463905 [Multi-domain] Cd Length: 84 Bit Score: 53.23 E-value: 6.19e-10
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Acetyltransf_10 | pfam13673 | Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ... |
57-161 | 7.19e-10 | |||
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. Pssm-ID: 463953 [Multi-domain] Cd Length: 128 Bit Score: 54.20 E-value: 7.19e-10
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NAT_SF | cd04301 | N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ... |
79-144 | 3.17e-09 | |||
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included. Pssm-ID: 173926 [Multi-domain] Cd Length: 65 Bit Score: 50.74 E-value: 3.17e-09
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MnaT | COG1247 | L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism]; |
55-161 | 6.86e-09 | |||
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism]; Pssm-ID: 440860 [Multi-domain] Cd Length: 163 Bit Score: 52.30 E-value: 6.86e-09
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COG3393 | COG3393 | Predicted acetyltransferase, GNAT family [General function prediction only]; |
106-161 | 9.93e-09 | |||
Predicted acetyltransferase, GNAT family [General function prediction only]; Pssm-ID: 442620 [Multi-domain] Cd Length: 86 Bit Score: 49.91 E-value: 9.93e-09
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PhnO | COG0454 | N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ... |
70-161 | 2.40e-08 | |||
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only]; Pssm-ID: 440222 [Multi-domain] Cd Length: 136 Bit Score: 50.44 E-value: 2.40e-08
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ArgA | COG1246 | N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ... |
81-161 | 1.49e-07 | |||
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis Pssm-ID: 440859 [Multi-domain] Cd Length: 132 Bit Score: 48.06 E-value: 1.49e-07
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PRK03624 | PRK03624 | putative acetyltransferase; Provisional |
108-165 | 8.58e-07 | |||
putative acetyltransferase; Provisional Pssm-ID: 235142 [Multi-domain] Cd Length: 140 Bit Score: 46.08 E-value: 8.58e-07
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rimI | TIGR01575 | ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related ... |
89-165 | 7.50e-06 | |||
ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification] Pssm-ID: 273701 [Multi-domain] Cd Length: 131 Bit Score: 43.47 E-value: 7.50e-06
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ElaA | COG2153 | Predicted N-acyltransferase, GNAT family [General function prediction only]; |
79-161 | 4.23e-04 | |||
Predicted N-acyltransferase, GNAT family [General function prediction only]; Pssm-ID: 441756 [Multi-domain] Cd Length: 134 Bit Score: 38.63 E-value: 4.23e-04
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RimL | COG1670 | Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ... |
53-165 | 4.45e-04 | |||
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 441276 [Multi-domain] Cd Length: 173 Bit Score: 38.83 E-value: 4.45e-04
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Eis | COG4552 | Predicted acetyltransferase [General function prediction only]; |
40-141 | 1.14e-03 | |||
Predicted acetyltransferase [General function prediction only]; Pssm-ID: 443616 [Multi-domain] Cd Length: 393 Bit Score: 38.34 E-value: 1.14e-03
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PTZ00330 | PTZ00330 | acetyltransferase; Provisional |
87-171 | 1.18e-03 | |||
acetyltransferase; Provisional Pssm-ID: 140351 [Multi-domain] Cd Length: 147 Bit Score: 37.51 E-value: 1.18e-03
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Blast search parameters | ||||
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