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Conserved domains on  [gi|19338620|gb|AAL86734|]
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mucin variant MUC-1CT80 [synthetic construct]

Protein Classification

Herpes_BLLF1 and SEA domain-containing protein( domain architecture ID 13558016)

Herpes_BLLF1 and SEA domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 254-372 3.01e-43

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


:

Pssm-ID: 214554  Cd Length: 121  Bit Score: 148.71  E-value: 3.01e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    254 PQLSTGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQG----GFLGLSNIKFRPGSVVVQLTLAFRE 329
Cdd:smart00200   1 PTQSFGVSLSVLSVEGENLQYSPSLEDPSSEEYQELVRDVEKLLEQIYGKTdlkpDFVGTEVIEFRNGSVVVDLGLLFNE 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 19338620    330 GTINVHDVETQFNQYKTEAAsrYNLTISDVSVSDVPFPFSAQS 372
Cdd:smart00200  81 GVTNGQDVEEDLLQVIKQAA--YSLKITNVNVVDVLDPDSADS 121
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 55-260 1.64e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 47.60  E-value: 1.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    55 SMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAatwGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPP 134
Cdd:pfam05109 428 TTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPAST---GPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAP 504

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   135 AHGVTSAPDTRPAPGSTAPPAHGVTSAPD-NRPALGSTAPpvhnvtsasgsaSGSASTLVHNGTSAR-ATTTPASKSTpf 212
Cdd:pfam05109 505 DMTSPTSAVTTPTPNATSPTPAVTTPTPNaTSPTLGKTSP------------TSAVTTPTPNATSPTpAVTTPTPNAT-- 570

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 19338620   213 sIPSHHSDTPTTLASHSTKTDASSTHHSTVPPLTSSNHSTSPQLSTGV 260
Cdd:pfam05109 571 -IPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPV 617
 
Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 254-372 3.01e-43

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 148.71  E-value: 3.01e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    254 PQLSTGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQG----GFLGLSNIKFRPGSVVVQLTLAFRE 329
Cdd:smart00200   1 PTQSFGVSLSVLSVEGENLQYSPSLEDPSSEEYQELVRDVEKLLEQIYGKTdlkpDFVGTEVIEFRNGSVVVDLGLLFNE 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 19338620    330 GTINVHDVETQFNQYKTEAAsrYNLTISDVSVSDVPFPFSAQS 372
Cdd:smart00200  81 GVTNGQDVEEDLLQVIKQAA--YSLKITNVNVVDVLDPDSADS 121
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 262-328 6.93e-11

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 58.79  E-value: 6.93e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 19338620   262 FFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQ----GGFLGLSNIKFRP--GSVVVQLTLAFR 328
Cdd:pfam01390   2 YYTGSFKITNLQYTPDLGNPSSQEFKSLSRRIESLLNELFRNsslrKQYIKSHVLRLRPdgGSVVVDVVLVFR 74
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 55-260 1.64e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 47.60  E-value: 1.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    55 SMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAatwGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPP 134
Cdd:pfam05109 428 TTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPAST---GPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAP 504

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   135 AHGVTSAPDTRPAPGSTAPPAHGVTSAPD-NRPALGSTAPpvhnvtsasgsaSGSASTLVHNGTSAR-ATTTPASKSTpf 212
Cdd:pfam05109 505 DMTSPTSAVTTPTPNATSPTPAVTTPTPNaTSPTLGKTSP------------TSAVTTPTPNATSPTpAVTTPTPNAT-- 570

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 19338620   213 sIPSHHSDTPTTLASHSTKTDASSTHHSTVPPLTSSNHSTSPQLSTGV 260
Cdd:pfam05109 571 -IPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPV 617
PHA03247 PHA03247
large tegument protein UL36; Provisional
 79-175 3.98e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 3.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    79 TLAPATEPASGSAATwgqDVTSVPVTRPALGSTtPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGV 158
Cdd:PHA03247 2736 PAAPAPPAVPAGPAT---PGGPARPARPPTTAG-PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV 2811

                          90
                  ....*....|....*..
gi 19338620   159 TSAPDNRPALGSTAPPV 175
Cdd:PHA03247 2812 LAPAAALPPAASPAGPL 2828
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
58-250 2.62e-03

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 40.12  E-value: 2.62e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620  58 SSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHG 137
Cdd:COG3469  20 VTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVAT 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620 138 VTSAPDTRPAPGSTAPPAHGVTSAPDNRPALGSTAP---PVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSI 214
Cdd:COG3469 100 STASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTsgaSATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTP 179

                       170       180       190
                ....*....|....*....|....*....|....*.
gi 19338620 215 PSHHSDTPTTLASHSTKTDASSTHHSTVPPLTSSNH 250
Cdd:COG3469 180 SATTTATATTASGATTPSATTTATTTGPPTPGLPKH 215
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 95-168 8.40e-03

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 38.34  E-value: 8.40e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19338620    95 GQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAhgvTSAPDTRPAPGSTAPPAHGVTSAPDNRPAL 168
Cdd:TIGR00601  80 GTGKVAPPAATPTSAPTPTPSPPASPASGMSAAPASAVEEK---SPSEESATATAPESPSTSVPSSGSDAASTL 150
 
Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 254-372 3.01e-43

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 148.71  E-value: 3.01e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    254 PQLSTGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQG----GFLGLSNIKFRPGSVVVQLTLAFRE 329
Cdd:smart00200   1 PTQSFGVSLSVLSVEGENLQYSPSLEDPSSEEYQELVRDVEKLLEQIYGKTdlkpDFVGTEVIEFRNGSVVVDLGLLFNE 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 19338620    330 GTINVHDVETQFNQYKTEAAsrYNLTISDVSVSDVPFPFSAQS 372
Cdd:smart00200  81 GVTNGQDVEEDLLQVIKQAA--YSLKITNVNVVDVLDPDSADS 121
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 262-328 6.93e-11

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 58.79  E-value: 6.93e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 19338620   262 FFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQ----GGFLGLSNIKFRP--GSVVVQLTLAFR 328
Cdd:pfam01390   2 YYTGSFKITNLQYTPDLGNPSSQEFKSLSRRIESLLNELFRNsslrKQYIKSHVLRLRPdgGSVVVDVVLVFR 74
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 55-260 1.64e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 47.60  E-value: 1.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    55 SMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAatwGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPP 134
Cdd:pfam05109 428 TTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPAST---GPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAP 504

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   135 AHGVTSAPDTRPAPGSTAPPAHGVTSAPD-NRPALGSTAPpvhnvtsasgsaSGSASTLVHNGTSAR-ATTTPASKSTpf 212
Cdd:pfam05109 505 DMTSPTSAVTTPTPNATSPTPAVTTPTPNaTSPTLGKTSP------------TSAVTTPTPNATSPTpAVTTPTPNAT-- 570

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 19338620   213 sIPSHHSDTPTTLASHSTKTDASSTHHSTVPPLTSSNHSTSPQLSTGV 260
Cdd:pfam05109 571 -IPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPV 617
PHA03247 PHA03247
large tegument protein UL36; Provisional
 79-175 3.98e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 3.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    79 TLAPATEPASGSAATwgqDVTSVPVTRPALGSTtPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGV 158
Cdd:PHA03247 2736 PAAPAPPAVPAGPAT---PGGPARPARPPTTAG-PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV 2811

                          90
                  ....*....|....*..
gi 19338620   159 TSAPDNRPALGSTAPPV 175
Cdd:PHA03247 2812 LAPAAALPPAASPAGPL 2828
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 81-179 9.98e-05

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 45.08  E-value: 9.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   81 APATEPASGSAA---TWGQDVTSVPVTRPalgSTTPPAHDVTSAPDN--KPAPGSTAPPAHGVTSAPDTRPAPGSTAPPA 155
Cdd:PLN02217 567 GSTNSTPTGSAAssnTTFSSDSPSTVVAP---STSPPAGHLGSPPATpsKIVSPSTSPPASHLGSPSTTPSSPESSIKVA 643

                         90       100
                 ....*....|....*....|....
gi 19338620  156 HGVTSAPDNRPALGSTAPPVHNVT 179
Cdd:PLN02217 644 STETASPESSIKVASTESSVSMVS 667
PHA03247 PHA03247
large tegument protein UL36; Provisional
 102-254 1.66e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 1.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   102 PVTRPALGSTTPPAHDVTSAPDNKPAPGSTAP-------PAHGVTSAPDTRPAPGSTAPPAHGVTSAPDNRPAlgstAPP 174
Cdd:PHA03247 2686 RAARPTVGSLTSLADPPPPPPTPEPAPHALVSatplppgPAAARQASPALPAAPAPPAVPAGPATPGGPARPA----RPP 2761

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   175 vhnvtsASGSASGSASTLVHNGTSARATTTPASKSTPFSI-----PSHHSDTPTTLASHSTKTDASSTHHSTVPPLTSSN 249
Cdd:PHA03247 2762 ------TTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESReslpsPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQ 2835


                  ....*
gi 19338620   250 HSTSP 254
Cdd:PHA03247 2836 PTAPP 2840
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 86-261 3.55e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.24  E-value: 3.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    86 PASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAhgvTSAPDNR 165
Cdd:PHA03307   55 VVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPA---SPPPSPA 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   166 PALGSTAPPVHNVTSASGSASGSAStlVHNGTSARATTTPASKSTPFSIPSHHSDTPTTlASHSTKTDASSTHHSTVPPL 245
Cdd:PHA03307  132 PDLSEMLRPVGSPGPPPAASPPAAG--ASPAAVASDAASSRQAALPLSSPEETARAPSS-PPAEPPPSTPPAAASPRPPR 208

                         170
                  ....*....|....*.
gi 19338620   246 TSSNHSTSPQLSTGVS 261
Cdd:PHA03307  209 RSSPISASASSPAPAP 224
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 23-258 4.96e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.85  E-value: 4.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    23 GSGHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPaTEPASGSAATWGQDVTSVP 102
Cdd:PHA03307  100 PAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASP-AAVASDAASSRQAALPLSS 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   103 VTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPG-STAPPAHGVTSAPDNRPALGSTAPPvHNVTSA 181
Cdd:PHA03307  179 PEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGrSAADDAGASSSDSSSSESSGCGWGP-ENECPL 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   182 SGSASGSASTLV---HNGTSARATTTPASKSTPFSIPS-----HHSDTPTTLASHSTKTDASSTHHSTVPPLTSSNHSTS 253
Cdd:PHA03307  258 PRPAPITLPTRIweaSGWNGPSSRPGPASSSSSPRERSpspspSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSR 337


                  ....*
gi 19338620   254 PQLST 258
Cdd:PHA03307  338 GAAVS 342
PHA03247 PHA03247
large tegument protein UL36; Provisional
 23-224 5.40e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 5.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    23 GSGHASSTPGGEKeTSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQG-QDVTLAPATEPASGSAATWGQDVTSV 101
Cdd:PHA03247 2631 PSPAANEPDPHPP-PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRpRRRAARPTVGSLTSLADPPPPPPTPE 2709

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   102 PVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSA----PDTRPAPGSTA-PPAHGVTSAPDNRPALGSTAPPVH 176
Cdd:PHA03247 2710 PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAtpggPARPARPPTTAgPPAPAPPAAPAAGPPRRLTRPAVA 2789

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 19338620   177 NVTSASGSASGSASTLVHngtsARATTTPASKSTPFSIPSHHSDTPTT 224
Cdd:PHA03247 2790 SLSESRESLPSPWDPADP----PAAVLAPAAALPPAASPAGPLPPPTS 2833
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 24-258 7.04e-04

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.25  E-value: 7.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    24 SGHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVPV 103
Cdd:pfam17823  78 AAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAA 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   104 TRPALGSTTPPaHDVTSAPDNKPAPGSTAPPAHGVTSAPDT--RPAPGSTAPPAHGVTSAPDN-RPALGSTAPPVHNVTS 180
Cdd:pfam17823 158 PRAAIAAASAP-HAASPAPRTAASSTTAASSTTAASSAPTTaaSSAPATLTPARGISTAATATgHPAAGTALAAVGNSSP 236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   181 ASGSASGSASTLVHN--GTSARATTTPASKSTPFSIPSHHSDTPTtlASHSTKTDASSthHSTVPPLTSSNHSTSPQLST 258
Cdd:pfam17823 237 AAGTVTAAVGTVTPAalATLAAAAGTVASAAGTINMGDPHARRLS--PAKHMPSDTMA--RNPAAPMGAQAQGPIIQVST 312
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
31-227 8.54e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.14  E-value: 8.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   31 PGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSsttqgqdVTLAPATEPASGSAATWGQDVTSVPVTRPAlgs 110
Cdd:PRK07003 362 VTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTA-------VTGAAGAALAPKAAAAAAATRAEAPPAAPA--- 431

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620  111 tTPPAHDVTSAPDNKPAPGSTAPPAhgvTSAPDTRPAPGSTAPPAhgvTSAPDNRPAlGSTAPPVHNVTSASGSASGSAS 190
Cdd:PRK07003 432 -PPATADRGDDAADGDAPVPAKANA---RASADSRCDERDAQPPA---DSGSASAPA-SDAPPDAAFEPAPRAAAPSAAT 503

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 19338620  191 TLVHNGTSARATTTPASKSTPFSIPSHHSDTPTTLAS 227
Cdd:PRK07003 504 PAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAA 540
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 73-254 9.98e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.83  E-value: 9.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    73 TQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPD-TRPAPGST 151
Cdd:pfam05109 463 STGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNaTSPTLGKT 542

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   152 APPAHGVTSAPDN---RPALGSTAPPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSIPSHHSDTPTTLASH 228
Cdd:pfam05109 543 SPTSAVTTPTPNAtspTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPP 622

                         170       180
                  ....*....|....*....|....*.
gi 19338620   229 STKTDASSTHHSTVPPLTSSNHSTSP 254
Cdd:pfam05109 623 KNATSAVTTGQHNITSSSTSSMSLRP 648
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 28-253 1.02e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.83  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    28 SSTPGGEkeTSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPA 107
Cdd:pfam05109 475 SPTPAGT--TSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPT 552

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   108 LGSTTPPAHDVTSAPDNK-PAPGSTAPPAHGVTSAPD-TRPAPGSTAPPAHGVtsapdNRPALGSTAPPVhnVTSASGSA 185
Cdd:pfam05109 553 PNATSPTPAVTTPTPNATiPTLGKTSPTSAVTTPTPNaTSPTVGETSPQANTT-----NHTLGGTSSTPV--VTSPPKNA 625

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19338620   186 SGSASTLVHNGTSARATTT---PASKSTPFSiPSHHSDTPTTLASHSTKTDASSTHHSTVPPLTSSNHSTS 253
Cdd:pfam05109 626 TSAVTTGQHNITSSSTSSMslrPSSISETLS-PSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVS 695
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 92-175 1.78e-03

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 41.03  E-value: 1.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620    92 ATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAhgvtSAPDTRPAPGSTAPPAHGVTSAPDNRPALGST 171
Cdd:PRK12270   34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAA----AAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPA 109


                  ....
gi 19338620   172 APPV 175
Cdd:PRK12270  110 AAAV 113
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 81-175 2.32e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 2.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   81 APATEPASGSAATwgqDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTA---PPAHGVTSAPDTRPAPGSTAPPAHG 157
Cdd:PRK14951 396 QAAAAPAPAAAPA---AAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAvalAPAPPAQAAPETVAIPVRVAPEPAV 472

                         90
                 ....*....|....*...
gi 19338620  158 VTSAPDnrPALGSTAPPV 175
Cdd:PRK14951 473 ASAAPA--PAAAPAAARL 488
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
86-229 2.47e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.63  E-value: 2.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   86 PASGSAATwgqDVTSVPVTRPALGSTTPPAhdvtSAPDNKPAPGSTAPPAHGVTSAPDTR-PAPGSTAPPAHGVTSAPDN 164
Cdd:PRK12323 374 PATAAAAP---VAQPAPAAAAPAAAAPAPA----APPAAPAAAPAAAAAARAVAAAPARRsPAPEALAAARQASARGPGG 446

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19338620  165 RPALGSTAPPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSIPShHSDTPTTLASHS 229
Cdd:PRK12323 447 APAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPP-WEELPPEFASPA 510
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
58-250 2.62e-03

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 40.12  E-value: 2.62e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620  58 SSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHG 137
Cdd:COG3469  20 VTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVAT 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620 138 VTSAPDTRPAPGSTAPPAHGVTSAPDNRPALGSTAP---PVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSI 214
Cdd:COG3469 100 STASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTsgaSATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTP 179

                       170       180       190
                ....*....|....*....|....*....|....*.
gi 19338620 215 PSHHSDTPTTLASHSTKTDASSTHHSTVPPLTSSNH 250
Cdd:COG3469 180 SATTTATATTASGATTPSATTTATTTGPPTPGLPKH 215
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 72-165 3.35e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 39.83  E-value: 3.35e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620  72 TTQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKP-------APGSTAPPAHGVTSAPDT 144
Cdd:COG3266 272 LGEQQEVSLPPAVAAQPAAAAAAQPSAVALPAAPAAAAAAAAPAEAAAPQPTAAKpvvtetaAPAAPAPEAAAAAAAPAA 351

                        90       100
                ....*....|....*....|.
gi 19338620 145 RPAPGSTAPPAHGVTSAPDNR 165
Cdd:COG3266 352 PAVAKKLAADEQWLASQPASH 372
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 77-174 3.55e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 39.79  E-value: 3.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   77 DVTLAPATEPASGSAAtwgqdVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAhGVTSAPDTRPAPGS--TAPP 154
Cdd:PRK14950 357 EALLVPVPAPQPAKPT-----AAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPP-PVPPRPVAPPVPHTpeSAPK 430

                         90       100
                 ....*....|....*....|
gi 19338620  155 AHGVTSAPDNRPALGSTAPP 174
Cdd:PRK14950 431 LTRAAIPVDEKPKYTPPAPP 450
PRK04654 PRK04654
sec-independent translocase; Provisional
 77-173 4.05e-03

sec-independent translocase; Provisional


Pssm-ID: 135173 [Multi-domain]  Cd Length: 214  Bit Score: 38.64  E-value: 4.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   77 DVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAhdvtsapdnkPAPGSTAPPA-HG-VTSAPDTRPAPGSTAPP 154
Cdd:PRK04654 118 DLSASAQVDAAAGAEPGAGQAHTPVPAPAPVIAQAQPIA----------PAPHQTLVPApHDtIVPAPHAAHLPSAPATP 187

                         90
                 ....*....|....*....
gi 19338620  155 ahgVTSAPDNRPALGSTAP 173
Cdd:PRK04654 188 ---VSVAPVDAGTSASPTP 203
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 76-179 4.48e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 39.46  E-value: 4.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   76 QDVTLAPATEPASGSAATWGQdVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPpa 155
Cdd:PRK07994 362 AAPLPEPEVPPQSAAPAASAQ-ATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKA-- 438

                         90       100
                 ....*....|....*....|....
gi 19338620  156 hgvtsaPDNRPALGSTAPPVHNVT 179
Cdd:PRK07994 439 ------KKSEPAAASRARPVNSAL 456
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
80-153 6.15e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 38.99  E-value: 6.15e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19338620   80 LAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPA-----PGSTAPPAHGVTSAPDTRPAPGSTAP 153
Cdd:PRK14971 386 PAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAavpvnPPSTAPQAVRPAQFKEEKKIPVSKVS 464
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 83-230 6.55e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 38.89  E-value: 6.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   83 ATEPASGSAATWGQDVTSVPVTRPAlgsttpPAHDVTSAPdnkPAPGSTAPPAHGVTSAPDTRPAPGSTAppahGVTSAP 162
Cdd:PRK14959 407 GTAPAAGMTPSSAAPATPAPSAAPS------PRVPWDDAP---PAPPRSGIPPRPAPRMPEASPVPGAPD----SVASAS 473

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19338620  163 DNRPALGS-TAPPVHNVTSASGSASGSASTLVHNGTSARATTTpASKSTPfsipsHHSDTPTTLASHST 230
Cdd:PRK14959 474 DAPPTLGDpSDTAEHTPSGPRTWDGFLEFCQGRNGQGGRLATV-LRQATP-----EHADGRLRLATMSS 536
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 72-175 6.96e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.20  E-value: 6.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   72 TTQGQDVTLAPATEPASGS--AATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPG 149
Cdd:PRK07764 634 AAPAEASAAPAPGVAAPEHhpKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQ 713

                         90       100
                 ....*....|....*....|....*.
gi 19338620  150 STAPPAHGVTSAPDNRPALGSTAPPV 175
Cdd:PRK07764 714 ADDPAAQPPQAAQGASAPSPAADDPV 739
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 81-174 7.98e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 38.81  E-value: 7.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   81 APATEPASGSAATWGQDVTSVPVTRPAlGSTTPPAHDVTSAPDNKPAPGSTAPPAHGvtsAPDTRPAPGSTAPPAHGVTS 160
Cdd:PRK07764 405 APAAAPAPAAAAPAAAAAPAPAAAPQP-APAPAPAPAPPSPAGNAPAGGAPSPPPAA---APSAQPAPAPAAAPEPTAAP 480

                         90
                 ....*....|....
gi 19338620  161 APDNRPALGSTAPP 174
Cdd:PRK07764 481 APAPPAAPAPAAAP 494
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 95-168 8.40e-03

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 38.34  E-value: 8.40e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19338620    95 GQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAhgvTSAPDTRPAPGSTAPPAHGVTSAPDNRPAL 168
Cdd:TIGR00601  80 GTGKVAPPAATPTSAPTPTPSPPASPASGMSAAPASAVEEK---SPSEESATATAPESPSTSVPSSGSDAASTL 150
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 45-151 9.18e-03

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 38.53  E-value: 9.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19338620   45 VPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATwgQDVTSVPVTRPalgSTTPPAHDVTSAPDN 124
Cdd:PLN02217 558 IPGLFAGNPGSTNSTPTGSAASSNTTFSSDSPSTVVAPSTSPPAGHLGS--PPATPSKIVSP---STSPPASHLGSPSTT 632

                         90       100
                 ....*....|....*....|....*..
gi 19338620  125 KPAPGSTAPPAHGVTSAPDTRPAPGST 151
Cdd:PLN02217 633 PSSPESSIKVASTETASPESSIKVAST 659
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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