|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
71-321 |
3.95e-24 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 101.93 E-value: 3.95e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 71 LYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVgplpKSLEDLQLTHNKIT 150
Cdd:COG4886 51 LLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNL----TNLESLDLSGNQLT 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 151 KLG-SFEGLVNLTFIHLQHNRLKEdaVSAAFKGLKSLEYLDLSFNQIARLPSGLP--VSLLTLYLDNNKISNIPDEyFKR 227
Cdd:COG4886 127 DLPeELANLTNLKELDLSNNQLTD--LPEPLGNLTNLKSLDLSNNQLTDLPEELGnlTNLKELDLSNNQITDLPEP-LGN 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 228 FNALQYLRLSHNELADsgIPGNSFNVSSLVELDLSYNKLKNIPTVNE--NLENYYLEVNQLEkfDIKSFCKIlgplsySK 305
Cdd:COG4886 204 LTNLEELDLSGNQLTD--LPEPLANLTNLETLDLSNNQLTDLPELGNltNLEELDLSNNQLT--DLPPLANL------TN 273
|
250
....*....|....*.
gi 30582253 306 IKHLRLDGNRISETSL 321
Cdd:COG4886 274 LKTLDLSNNQLTDLKL 289
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
42-242 |
3.13e-13 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 70.50 E-value: 3.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 42 NCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQwlildhnllENSKIKGRVFSKLKQ-LK 119
Cdd:PRK15370 174 DCLKNNKTELRLKILGLTTIPAcIPEQITTLILDNNELKSLPENLQGNIKTLY---------ANSNQLTSIPATLPDtIQ 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 120 KLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSF--EGLVNL------------------TFIHLQHNRLK------- 172
Cdd:PRK15370 245 EMELSINRITELPERLPSALQSLDLFHNKISCLPENlpEELRYLsvydnsirtlpahlpsgiTHLNVQSNSLTalpetlp 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 173 ---------EDAVSAAFKGLK-SLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKrfnALQYLRLSHNELA 242
Cdd:PRK15370 325 pglktleagENALTSLPASLPpELQVLDVSKNQITVLPETLPPTITTLDVSRNALTNLPENLPA---ALQIMQASRNNLV 401
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
66-200 |
5.76e-13 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 67.12 E-value: 5.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 66 PGIKYLYLRNNQIDHIDekAFENVTDLQWLILDHNLLEnsKIKGrvFSKLKQLKKLHINHN------------NLTE--- 130
Cdd:cd21340 24 KNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIE--KIEN--LENLVNLKKLYLGGNrisvveglenltNLEElhi 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 131 ----------------SVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKE-DAVSAAFKGLKSLEYLDLSF 193
Cdd:cd21340 98 enqrlppgekltfdprSLAALSNSLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDlEELLDLLSSWPSLRELDLTG 177
|
....*..
gi 30582253 194 NQIARLP 200
Cdd:cd21340 178 NPVCKKP 184
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
66-128 |
1.27e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.60 E-value: 1.27e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30582253 66 PGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLenSKIKGRVFSKLKQLKKLHINHNNL 128
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
37-71 |
8.24e-07 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 45.00 E-value: 8.24e-07
10 20 30
....*....|....*....|....*....|....*
gi 30582253 37 CAPECNCPesyPSAMYCDELKLKSVPMVPPGIKYL 71
Cdd:smart00013 2 CPAPCNCS---GTAVDCSGRGLTEVPLDLPPDTTL 33
|
|
| LRRNT |
pfam01462 |
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ... |
37-66 |
1.07e-06 |
|
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.
Pssm-ID: 396168 [Multi-domain] Cd Length: 28 Bit Score: 44.54 E-value: 1.07e-06
10 20 30
....*....|....*....|....*....|
gi 30582253 37 CAPECNCPesyPSAMYCDELKLKSVPMVPP 66
Cdd:pfam01462 2 CPVPCHCS---ATVVNCSDRGLTAVPRDLP 28
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
71-321 |
3.95e-24 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 101.93 E-value: 3.95e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 71 LYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVgplpKSLEDLQLTHNKIT 150
Cdd:COG4886 51 LLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNL----TNLESLDLSGNQLT 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 151 KLG-SFEGLVNLTFIHLQHNRLKEdaVSAAFKGLKSLEYLDLSFNQIARLPSGLP--VSLLTLYLDNNKISNIPDEyFKR 227
Cdd:COG4886 127 DLPeELANLTNLKELDLSNNQLTD--LPEPLGNLTNLKSLDLSNNQLTDLPEELGnlTNLKELDLSNNQITDLPEP-LGN 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 228 FNALQYLRLSHNELADsgIPGNSFNVSSLVELDLSYNKLKNIPTVNE--NLENYYLEVNQLEkfDIKSFCKIlgplsySK 305
Cdd:COG4886 204 LTNLEELDLSGNQLTD--LPEPLANLTNLETLDLSNNQLTDLPELGNltNLEELDLSNNQLT--DLPPLANL------TN 273
|
250
....*....|....*.
gi 30582253 306 IKHLRLDGNRISETSL 321
Cdd:COG4886 274 LKTLDLSNNQLTDLKL 289
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
68-314 |
7.84e-22 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 95.39 E-value: 7.84e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 68 IKYLYLRNNQIDHIDEkAFENVTDLQWLILDHNLLENSkikGRVFSKLKQLKKLHINHNNLT---ESVGPLPKsLEDLQL 144
Cdd:COG4886 115 LESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDL---PEPLGNLTNLKSLDLSNNQLTdlpEELGNLTN-LKELDL 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 145 THNKITKLG-SFEGLVNLTFIHLQHNRLKEdaVSAAFKGLKSLEYLDLSFNQIARLP--SGLPvSLLTLYLDNNKISNIP 221
Cdd:COG4886 190 SNNQITDLPePLGNLTNLEELDLSGNQLTD--LPEPLANLTNLETLDLSNNQLTDLPelGNLT-NLEELDLSNNQLTDLP 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 222 DEyfKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPL 301
Cdd:COG4886 267 PL--ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSL 344
|
250
....*....|...
gi 30582253 302 SYSKIKHLRLDGN 314
Cdd:COG4886 345 SLLALLTLLLLLN 357
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
66-291 |
1.82e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 76.90 E-value: 1.82e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 66 PGIKYLYLRNNQIDHIDEkAFENVTDLQWLILDHNLLENSkikGRVFSKLKQLKKLHINHNNLT---ESVGPLpKSLEDL 142
Cdd:COG4886 159 TNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL---PEPLGNLTNLEELDLSGNQLTdlpEPLANL-TNLETL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 143 QLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAafkGLKSLEYLDLSFNQIARLP-SGLPVSLLTLYLDNNKISNIP 221
Cdd:COG4886 234 DLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLA---NLTNLKTLDLSNNQLTDLKlKELELLLGLNSLLLLLLLLNL 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 222 DEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDI 291
Cdd:COG4886 311 LELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLL 380
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
42-242 |
3.13e-13 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 70.50 E-value: 3.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 42 NCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQwlildhnllENSKIKGRVFSKLKQ-LK 119
Cdd:PRK15370 174 DCLKNNKTELRLKILGLTTIPAcIPEQITTLILDNNELKSLPENLQGNIKTLY---------ANSNQLTSIPATLPDtIQ 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 120 KLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSF--EGLVNL------------------TFIHLQHNRLK------- 172
Cdd:PRK15370 245 EMELSINRITELPERLPSALQSLDLFHNKISCLPENlpEELRYLsvydnsirtlpahlpsgiTHLNVQSNSLTalpetlp 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 173 ---------EDAVSAAFKGLK-SLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKrfnALQYLRLSHNELA 242
Cdd:PRK15370 325 pglktleagENALTSLPASLPpELQVLDVSKNQITVLPETLPPTITTLDVSRNALTNLPENLPA---ALQIMQASRNNLV 401
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
66-200 |
5.76e-13 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 67.12 E-value: 5.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 66 PGIKYLYLRNNQIDHIDekAFENVTDLQWLILDHNLLEnsKIKGrvFSKLKQLKKLHINHN------------NLTE--- 130
Cdd:cd21340 24 KNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIE--KIEN--LENLVNLKKLYLGGNrisvveglenltNLEElhi 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 131 ----------------SVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKE-DAVSAAFKGLKSLEYLDLSF 193
Cdd:cd21340 98 enqrlppgekltfdprSLAALSNSLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDlEELLDLLSSWPSLRELDLTG 177
|
....*..
gi 30582253 194 NQIARLP 200
Cdd:cd21340 178 NPVCKKP 184
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
112-243 |
6.02e-11 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 61.34 E-value: 6.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 112 FSKLKQLKKLHINHNNLT--ESVGPLPKsLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLkedAVSAAFKGLKSLEYL 189
Cdd:cd21340 20 LSLCKNLKVLYLYDNKITkiENLEFLTN-LTHLYLQNNQIEKIENLENLVNLKKLYLGGNRI---SVVEGLENLTNLEEL 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30582253 190 DLSfNQiaRLPSGLPV------------SLLTLYLDNNKISNIpdEYFKRFNALQYLRLSHNELAD 243
Cdd:cd21340 96 HIE-NQ--RLPPGEKLtfdprslaalsnSLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISD 156
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
66-286 |
1.01e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 62.26 E-value: 1.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 66 PGIKYLYLRNNQIDHIDEkAFENVTDLQWLILDHNLLENskiKGRVFSKLKQLKKLHINHNNLTE--SVGPLPKsLEDLQ 143
Cdd:COG4886 182 TNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTD---LPEPLANLTNLETLDLSNNQLTDlpELGNLTN-LEELD 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 144 LTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVS--AAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIP 221
Cdd:COG4886 257 LSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKelELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVT 336
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30582253 222 DEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQL 286
Cdd:COG4886 337 LTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVL 401
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
110-266 |
1.88e-09 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 59.09 E-value: 1.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 110 RVFSKLKQLKKLHINHNNLTESVGPLP---KSLEDLQLTHNKIT-KLGSFEGLVNLTFIHLQHNRLKEdAVSAAFKGLKS 185
Cdd:PLN00113 422 SEFTKLPLVYFLDISNNNLQGRINSRKwdmPSLQMLSLARNKFFgGLPDSFGSKRLENLDLSRNQFSG-AVPRKLGSLSE 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 186 LEYLDLSFNQIA-RLPSGLPV--SLLTLYLDNNKIS-NIPDEyFKRFNALQYLRLSHNELADSgIPGNSFNVSSLVELDL 261
Cdd:PLN00113 501 LMQLKLSENKLSgEIPDELSSckKLVSLDLSHNQLSgQIPAS-FSEMPVLSQLDLSQNQLSGE-IPKNLGNVESLVQVNI 578
|
....*
gi 30582253 262 SYNKL 266
Cdd:PLN00113 579 SHNHL 583
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
31-321 |
9.26e-09 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 56.71 E-value: 9.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 31 GQSSPNCAPECnCPESYPSAMYCDElKLKSVPMVPPGIKYLYLRNNQIDHIDekafenvtdlqwlILDHNLLENSkIKGR 110
Cdd:PRK15387 209 GESGLTTLPDC-LPAHITTLVIPDN-NLTSLPALPPELRTLEVSGNQLTSLP-------------VLPPGLLELS-IFSN 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 111 VFSKLKQLK----KLHINHNNLTeSVGPLPKSLEDLQLTHNKITKLGSFEGlvNLTFIHLQHNRLkedavsAAFKGLKS- 185
Cdd:PRK15387 273 PLTHLPALPsglcKLWIFGNQLT-SLPVLPPGLQELSVSDNQLASLPALPS--ELCKLWAYNNQL------TSLPTLPSg 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 186 LEYLDLSFNQIARLPSgLPVSLLTLYLDNNKISNIPdeyfKRFNALQYLRLSHNELadSGIPgnsFNVSSLVELDLSYNK 265
Cdd:PRK15387 344 LQELSVSDNQLASLPT-LPSELYKLWAYNNRLTSLP----ALPSGLKELIVSGNRL--TSLP---VLPSELKELMVSGNR 413
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 30582253 266 LKNIPTVNENLENYYLEVNQLEKFDiKSFckilgpLSYSKIKHLRLDGNRISETSL 321
Cdd:PRK15387 414 LTSLPMLPSGLLSLSVYRNQLTRLP-ESL------IHLSSETTVNLEGNPLSERTL 462
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
66-128 |
1.27e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.60 E-value: 1.27e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30582253 66 PGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLenSKIKGRVFSKLKQLKKLHINHNNL 128
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
92-317 |
2.33e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 55.62 E-value: 2.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 92 LQWLILDHNLLeNSKIKGRVFSKLKQLKKLHINHNNLTesvGPLPKS----LEDLQLTHNKIT-----KLGSFEglvNLT 162
Cdd:PLN00113 95 IQTINLSNNQL-SGPIPDDIFTTSSSLRYLNLSNNNFT---GSIPRGsipnLETLDLSNNMLSgeipnDIGSFS---SLK 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 163 FIHLQHNRLKeDAVSAAFKGLKSLEYLDLSFNQiarLPSGLPV------SLLTLYLDNNKIS-NIPDEY----------- 224
Cdd:PLN00113 168 VLDLGGNVLV-GKIPNSLTNLTSLEFLTLASNQ---LVGQIPRelgqmkSLKWIYLGYNNLSgEIPYEIggltslnhldl 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 225 ------------FKRFNALQYLRLSHNELADSgIPGNSFNVSSLVELDLSYNKLK-NIPTVNENLENyyLEVnqLEKFDI 291
Cdd:PLN00113 244 vynnltgpipssLGNLKNLQYLFLYQNKLSGP-IPPSIFSLQKLISLDLSDNSLSgEIPELVIQLQN--LEI--LHLFSN 318
|
250 260
....*....|....*....|....*..
gi 30582253 292 KSFCKILGPL-SYSKIKHLRLDGNRIS 317
Cdd:PLN00113 319 NFTGKIPVALtSLPRLQVLQLWSNKFS 345
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
55-266 |
4.31e-08 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 54.41 E-value: 4.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 55 ELKLKSVPMVPPGIKYLYLRNNQID------HIDEKAFENvTDLQWLILDHNLLENSKIK--GRVFSKLKQLKKLHINHN 126
Cdd:COG5238 140 RINLIQVLKDPLGGNAVHLLGLAARlgllaaISMAKALQN-NSVETVYLGCNQIGDEGIEelAEALTQNTTVTTLWLKRN 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 127 NLTES-------VGPLPKSLEDLQLTHNKITKLGS---FEGLVNLTFIH---LQHNRLKED---AVSAAFKGLKSLEYLD 190
Cdd:COG5238 219 PIGDEgaeilaeALKGNKSLTTLDLSNNQIGDEGVialAEALKNNTTVEtlyLSGNQIGAEgaiALAKALQGNTTLTSLD 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 191 LSFNQI-----ARLPSGLPVS--LLTLYLDNNKISNipDEYFKRFNALQY------LRLSHNELADSG-------IPGNs 250
Cdd:COG5238 299 LSVNRIgdegaIALAEGLQGNktLHTLNLAYNGIGA--QGAIALAKALQEnttlhsLDLSDNQIGDEGaialakyLEGN- 375
|
250
....*....|....*.
gi 30582253 251 fnvSSLVELDLSYNKL 266
Cdd:COG5238 376 ---TTLRELNLGKNNI 388
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
44-204 |
4.41e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 54.70 E-value: 4.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 44 PESYPSAMYCDEL---KLKSVP-MVPPGIKYLYLRNNQIDHIDEKAFENVTDLqwlildhNLLENSkikgrvFSKLKQ-- 117
Cdd:PRK15370 257 PERLPSALQSLDLfhnKISCLPeNLPEELRYLSVYDNSIRTLPAHLPSGITHL-------NVQSNS------LTALPEtl 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 118 ---LKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGsfEGLV-NLTFIHLQHN---RLKEDAVSAafkglksLEYLD 190
Cdd:PRK15370 324 ppgLKTLEAGENALTSLPASLPPELQVLDVSKNQITVLP--ETLPpTITTLDVSRNaltNLPENLPAA-------LQIMQ 394
|
170
....*....|....
gi 30582253 191 LSFNQIARLPSGLP 204
Cdd:PRK15370 395 ASRNNLVRLPESLP 408
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
206-266 |
6.94e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 6.94e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30582253 206 SLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELadSGIPGNSF-NVSSLVELDLSYNKL 266
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFsGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
142-317 |
1.34e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 51.33 E-value: 1.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 142 LQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEdavSAAFKGLKSLEYLDLSFNQIARLP--SGLPvSLLTLYLDNNKISN 219
Cdd:cd21340 7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITK---IENLEFLTNLTHLYLQNNQIEKIEnlENLV-NLKKLYLGGNRISV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 220 IpdEYFKRFNALQYLRLSHNELAdsgiPGNSF--------NVS-SLVELDLSYNKLKNI-PTVN-ENLENYYLEVNQLEk 288
Cdd:cd21340 83 V--EGLENLTNLEELHIENQRLP----PGEKLtfdprslaALSnSLRVLNISGNNIDSLePLAPlRNLEQLDASNNQIS- 155
|
170 180
....*....|....*....|....*....
gi 30582253 289 fDIKSFCKILGPLSYskIKHLRLDGNRIS 317
Cdd:cd21340 156 -DLEELLDLLSSWPS--LRELDLTGNPVC 181
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
138-196 |
2.66e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.13 E-value: 2.66e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30582253 138 SLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAvSAAFKGLKSLEYLDLSFNQI 196
Cdd:pfam13855 2 NLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLS-PGAFSGLPSLRYLDLSGNRL 61
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
37-71 |
8.24e-07 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 45.00 E-value: 8.24e-07
10 20 30
....*....|....*....|....*....|....*
gi 30582253 37 CAPECNCPesyPSAMYCDELKLKSVPMVPPGIKYL 71
Cdd:smart00013 2 CPAPCNCS---GTAVDCSGRGLTEVPLDLPPDTTL 33
|
|
| LRRNT |
pfam01462 |
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ... |
37-66 |
1.07e-06 |
|
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.
Pssm-ID: 396168 [Multi-domain] Cd Length: 28 Bit Score: 44.54 E-value: 1.07e-06
10 20 30
....*....|....*....|....*....|
gi 30582253 37 CAPECNCPesyPSAMYCDELKLKSVPMVPP 66
Cdd:pfam01462 2 CPVPCHCS---ATVVNCSDRGLTAVPRDLP 28
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
117-171 |
1.59e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.82 E-value: 1.59e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30582253 117 QLKKLHINHNNLTeSVGPL----PKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRL 171
Cdd:pfam13855 2 NLRSLDLSNNRLT-SLDDGafkgLSNLKVLDLSNNLLTTLspGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
66-267 |
3.78e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 48.12 E-value: 3.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 66 PGIKYLYLRNNQIDHIDEKAFENVT---DLQWLILDHNLLENS--KIKGRVFSKLK-QLKKLHINHNNLT-ESVGPLPK- 137
Cdd:cd00116 81 CGLQELDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDRglRLLAKGLKDLPpALEKLVLGRNRLEgASCEALAKa 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 138 -----SLEDLQLTHNKITKLGS---FEGL---VNLTFIHLQHNRLKED---AVSAAFKGLKSLEYLDLSFNQI-----AR 198
Cdd:cd00116 161 lranrDLKELNLANNGIGDAGIralAEGLkanCNLEVLDLNNNGLTDEgasALAETLASLKSLEVLNLGDNNLtdagaAA 240
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30582253 199 LPSGLPV---SLLTLYLDNNKISNIPDEYFKRFnalqylrlshneLADSgipgnsfnvSSLVELDLSYNKLK 267
Cdd:cd00116 241 LASALLSpniSLLTLSLSCNDITDDGAKDLAEV------------LAEK---------ESLLELDLRGNKFG 291
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
160-217 |
5.11e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.28 E-value: 5.11e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30582253 160 NLTFIHLQHNRLKEDAVSAaFKGLKSLEYLDLSFNQIARLP----SGLPvSLLTLYLDNNKI 217
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGA-FKGLSNLKVLDLSNNLLTTLSpgafSGLP-SLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
88-266 |
5.72e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 47.92 E-value: 5.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 88 NVTDLQWLILDHNLLENSKikGRVFSKLKQLKKLHINHNNLTesvGPLPK------SLEDLQLTHNKITKL--GSFEGLV 159
Cdd:PLN00113 186 NLTSLEFLTLASNQLVGQI--PRELGQMKSLKWIYLGYNNLS---GEIPYeiggltSLNHLDLVYNNLTGPipSSLGNLK 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 160 NLTFIHLQHNRLKEDAVSAAFkGLKSLEYLDLSFN----QIARLPSGLPvSLLTLYLDNNKISNIPDEYFKRFNALQYLR 235
Cdd:PLN00113 261 NLQYLFLYQNKLSGPIPPSIF-SLQKLISLDLSDNslsgEIPELVIQLQ-NLEILHLFSNNFTGKIPVALTSLPRLQVLQ 338
|
170 180 190
....*....|....*....|....*....|.
gi 30582253 236 LSHNELAdSGIPGNSFNVSSLVELDLSYNKL 266
Cdd:PLN00113 339 LWSNKFS-GEIPKNLGKHNNLTVLDLSTNNL 368
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
155-319 |
1.76e-05 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 45.81 E-value: 1.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 155 FEGLVNLTFIHLQHNRLKEDAVSAAFKGL---KSLEYLDLSFNQIARLPSGL---------PVSLLTLYLDNNKISniPD 222
Cdd:cd00116 19 LPKLLCLQVLRLEGNTLGEEAAKALASALrpqPSLKELCLSLNETGRIPRGLqsllqgltkGCGLQELDLSDNALG--PD 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 223 -----EYFKRFNALQYLRLSHNELADSGIP----GNSFNVSSLVELDLSYNKLKNIPT--------VNENLENYYLEVNQ 285
Cdd:cd00116 97 gcgvlESLLRSSSLQELKLNNNGLGDRGLRllakGLKDLPPALEKLVLGRNRLEGASCealakalrANRDLKELNLANNG 176
|
170 180 190
....*....|....*....|....*....|....
gi 30582253 286 LEKFDIKSFCKILgpLSYSKIKHLRLDGNRISET 319
Cdd:cd00116 177 IGDAGIRALAEGL--KANCNLEVLDLNNNGLTDE 208
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
154-266 |
6.20e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 41.76 E-value: 6.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30582253 154 SFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIA-RLPSGLPVSLLTLYLDNNKIS-NIPDEyFKRFNAL 231
Cdd:PLN00113 88 AIFRLPYIQTINLSNNQLSGPIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSIPNLETLDLSNNMLSgEIPND-IGSFSSL 166
|
90 100 110
....*....|....*....|....*....|....*
gi 30582253 232 QYLRLSHNELADSgIPGNSFNVSSLVELDLSYNKL 266
Cdd:PLN00113 167 KVLDLGGNVLVGK-IPNSLTNLTSLEFLTLASNQL 200
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
137-174 |
5.81e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 34.14 E-value: 5.81e-03
10 20 30
....*....|....*....|....*....|....*...
gi 30582253 137 KSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKED 174
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNNKITD 38
|
|
|