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Conserved domains on  [gi|46242622|gb|AAS83443|]
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arylalkylamine N-acetyltransferase, partial [Eolophus roseicapilla]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10006981)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
23-175 2.00e-12

Predicted N-acetyltransferase YhbS [General function prediction only];


:

Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 61.64  E-value: 2.00e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622  23 FRCLSPEDAVSVFEIEREAFisVSGDCPLHLDEIRHFLNLcpELSLGWFEEGRLVAFIIGSLWDQErlsqaaltlhrPQG 102
Cdd:COG3153   1 IRPATPEDAEAIAALLRAAF--GPGREAELVDRLREDPAA--GLSLVAEDDGEIVGHVALSPVDID-----------GEG 65

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46242622 103 SAVHIHVLAVHRGCRQQGKGSILMWRYLQYLRGLpSARRALLMCQGFLVPFYQKCGFRALGPCAVAVGDMAFV 175
Cdd:COG3153  66 PALLLGPLAVDPEYRGQGIGRALMRAALEAARER-GARAVVLLGDPSLLPFYERFGFRPAGELGLTLGPDEVF 137
 
Name Accession Description Interval E-value
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
23-175 2.00e-12

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 61.64  E-value: 2.00e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622  23 FRCLSPEDAVSVFEIEREAFisVSGDCPLHLDEIRHFLNLcpELSLGWFEEGRLVAFIIGSLWDQErlsqaaltlhrPQG 102
Cdd:COG3153   1 IRPATPEDAEAIAALLRAAF--GPGREAELVDRLREDPAA--GLSLVAEDDGEIVGHVALSPVDID-----------GEG 65

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46242622 103 SAVHIHVLAVHRGCRQQGKGSILMWRYLQYLRGLpSARRALLMCQGFLVPFYQKCGFRALGPCAVAVGDMAFV 175
Cdd:COG3153  66 PALLLGPLAVDPEYRGQGIGRALMRAALEAARER-GARAVVLLGDPSLLPFYERFGFRPAGELGLTLGPDEVF 137
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 33-159 2.69e-10

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 55.22  E-value: 2.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622    33 SVFEIEREAFISVSGDCPLhlDEIRHFLNLCPELSLGWFEEGRLVAFIIGSLWDQErlsqaaltlhrpqGSAVHIHVLAV 112
Cdd:pfam00583   3 ALYELLSEEFPEPWPDEPL--DLLEDWDEDASEGFFVAEEDGELVGFASLSIIDDE-------------PPVGEIEGLAV 67

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 46242622   113 HRGCRQQGKGSILMWRYLQYLRGLpSARRALLMCQGF---LVPFYQKCGF 159
Cdd:pfam00583  68 APEYRGKGIGTALLQALLEWARER-GCERIFLEVAADnlaAIALYEKLGF 116
 
Name Accession Description Interval E-value
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
23-175 2.00e-12

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 61.64  E-value: 2.00e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622  23 FRCLSPEDAVSVFEIEREAFisVSGDCPLHLDEIRHFLNLcpELSLGWFEEGRLVAFIIGSLWDQErlsqaaltlhrPQG 102
Cdd:COG3153   1 IRPATPEDAEAIAALLRAAF--GPGREAELVDRLREDPAA--GLSLVAEDDGEIVGHVALSPVDID-----------GEG 65

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46242622 103 SAVHIHVLAVHRGCRQQGKGSILMWRYLQYLRGLpSARRALLMCQGFLVPFYQKCGFRALGPCAVAVGDMAFV 175
Cdd:COG3153  66 PALLLGPLAVDPEYRGQGIGRALMRAALEAARER-GARAVVLLGDPSLLPFYERFGFRPAGELGLTLGPDEVF 137
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 33-159 2.69e-10

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 55.22  E-value: 2.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622    33 SVFEIEREAFISVSGDCPLhlDEIRHFLNLCPELSLGWFEEGRLVAFIIGSLWDQErlsqaaltlhrpqGSAVHIHVLAV 112
Cdd:pfam00583   3 ALYELLSEEFPEPWPDEPL--DLLEDWDEDASEGFFVAEEDGELVGFASLSIIDDE-------------PPVGEIEGLAV 67

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 46242622   113 HRGCRQQGKGSILMWRYLQYLRGLpSARRALLMCQGF---LVPFYQKCGF 159
Cdd:pfam00583  68 APEYRGKGIGTALLQALLEWARER-GCERIFLEVAADnlaAIALYEKLGF 116
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 106-178 6.49e-06

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 43.41  E-value: 6.49e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46242622   106 HIHVLAVHRGCRQQGKGSILMWRYLQYLRGLPSARRALLM-CQGFLVPFYQKCGFRALGPCAVAVGdMAFVEME 178
Cdd:pfam13673  53 HISLLFVDPDYQGQGIGKALLEAVEDYAEKDGIKLSELTVnASPYAVPFYEKLGFRATGPEQEFNG-IRFVPME 125
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
68-164 8.33e-06

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 43.25  E-value: 8.33e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622  68 LGWFEEGRLVAfiigslwdqerlsqaALTLHRPQGSAVHIHVLAVHRGCRQQGKGSILMWRYLQYLRGLPsARRALLMCQ 147
Cdd:COG2153  37 LLAYDDGELVA---------------TARLLPPGDGEAKIGRVAVLPEYRGQGLGRALMEAAIEEARERG-ARRIVLSAQ 100

                        90
                ....*....|....*..
gi 46242622 148 GFLVPFYQKCGFRALGP 164
Cdd:COG2153 101 AHAVGFYEKLGFVPVGE 117
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 93-160 1.72e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 41.29  E-value: 1.72e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46242622    93 AALTLHRPQGSAVHIHvLAVHRGCRQQGKGSILMwRYLQYLRGLPSARRALLMCQGFLVPFYQKCGFR 160
Cdd:pfam13508  18 AALLPLDDEGALAELR-LAVHPEYRGQGIGRALL-EAAEAAAKEGGIKLLELETTNRAAAFYEKLGFE 83
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 72-183 7.66e-05

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 40.81  E-value: 7.66e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622  72 EEGRLVAFIIGSlwDQERLsQAALTLHRPQGSAVHIHVLAVHRGCRQQGKGSILMWRYLQYLRGLpSARRALLMC---QG 148
Cdd:COG0454  29 GSLAGAEFIAVD--DKGEP-IGFAGLRRLDDKVLELKRLYVLPEYRGKGIGKALLEALLEWARER-GCTALELDTldgNP 104

                        90       100       110
                ....*....|....*....|....*....|....*
gi 46242622 149 FLVPFYQKCGFRALGpcavAVGDMAFVEMEHAVRG 183
Cdd:COG0454 105 AAIRFYERLGFKEIE----RYVAYVGGEFEKELSL 135
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 93-175 3.59e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 38.10  E-value: 3.59e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622  93 AALTLHRPQGSAvHIHVLAVHRGCRQQGKGSILMWRYLQYLRGLpSARRALLMCQGF---LVPFYQKCGFRALGPCAVAV 169
Cdd:COG0456   3 ALLGLVDGGDEA-EIEDLAVDPEYRGRGIGRALLEAALERARER-GARRLRLEVREDneaAIALYEKLGFEEVGERPNYY 80


                ....*.
gi 46242622 170 GDMAFV 175
Cdd:COG0456  81 GDDALV 86
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 22-164 2.34e-03

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 36.51  E-value: 2.34e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622  22 EFRCLSPEDAVSVFEIEREAFIsvsgdcplhLDEIRHFLnlcpelslGWFEEGRLVAFIigslwdqerlsqaalTLHRPQ 101
Cdd:COG1246   2 TIRPATPDDVPAILELIRPYAL---------EEEIGEFW--------VAEEDGEIVGCA---------------ALHPLD 49

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46242622 102 GSAVHIHVLAVHRGCRQQGKGSILMWRYLQYLRGLpSARRALLMCQGFLVPFYQKCGFRALGP 164
Cdd:COG1246  50 EDLAELRSLAVHPDYRGRGIGRRLLEALLAEAREL-GLKRLFLLTTSAAIHFYEKLGFEEIDK 111
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
22-163 8.35e-03

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 35.36  E-value: 8.35e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46242622  22 EFRCLSPEDAVSVFEIEREAFISVS---GDCPLHLDEIRHFLNLCPELSLGWF---EEGRLVAFIIGSLWDQerlsqaal 95
Cdd:COG1247   3 TIRPATPEDAPAIAAIYNEAIAEGTatfETEPPSEEEREAWFAAILAPGRPVLvaeEDGEVVGFASLGPFRP-------- 74

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46242622  96 tlhRPQGSAVHIHVLAVHRGCRQQGKGSILMWRYLQYLRG----------LPSARRALlmcqgflvPFYQKCGFRALG 163
Cdd:COG1247  75 ---RPAYRGTAEESIYVDPDARGRGIGRALLEALIERARArgyrrlvavvLADNEASI--------ALYEKLGFEEVG 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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