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Conserved domains on  [gi|47156088|gb|AAT11933|]
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polyprotein, partial [Pennisetum mosaic virus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Poty_coat super family cl02961
Potyvirus coat protein;
67-299 1.09e-100

Potyvirus coat protein;


The actual alignment was detected with superfamily member pfam00767:

Pssm-ID: 279151  Cd Length: 243  Bit Score: 295.28  E-value: 1.09e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088    67 DVNVGTHGTVAVPKLKAMSSKMRLPLAKGKNIL-HVEFLLNYKPAQQDISNTRATRAEFDRWYDAVKNEYEV-DDTQMTV 144
Cdd:pfam00767   1 DVAAATSITFEVPRRKGFGALWRPPKQKGAATPnRIEKLKKYLPDQNDISNTRATQAQLNDWYEAVRDDYGQtEEEFMDT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088   145 IMSGLMVWCIENGCSPNIN--GVW-----TMMDGEEQRTFPLKPIIENASPTFRQIMHHFSDAAEA-YIEFRNATERYMP 216
Cdd:pfam00767  81 ILPGWIVWCIENGTSPENRkaGSWravimAMMEDEEQVLYPIEPIIINAQPTLRQIMRHFSDLARAqYAESRNQGKPYMP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088   217 RYGLQRNLTDYSLARYAFDFYEITSRTTARAKEAHMQMKAAAVRGSNTRMFGLDGNVGESQENTERHTAGDVSRNMHSLL 296
Cdd:pfam00767 161 KGGLKAGLADASLAAYAFDFYEDTSHDTARAREVHHQMKAAAVSGIKIRLFALAGPGSGQEEDTERHTVEDVAEGIHSLG 240


                  ...
gi 47156088   297 GVQ 299
Cdd:pfam00767 241 GAQ 243
tolA super family cl35847
cell envelope integrity inner membrane protein TolA; Provisional
 11-67 2.72e-07

cell envelope integrity inner membrane protein TolA; Provisional


The actual alignment was detected with superfamily member PRK09510:

Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 51.35  E-value: 2.72e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 47156088   11 QTEEQKKAAEEQRQKAAADAEAKRKAAADEEARKAREAEAERKRQADAAAKGKQDKD 67
Cdd:PRK09510 126 QAALKQKQAEEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAE 182
 
Name Accession Description Interval E-value
Poty_coat pfam00767
Potyvirus coat protein;
67-299 1.09e-100

Potyvirus coat protein;


Pssm-ID: 279151  Cd Length: 243  Bit Score: 295.28  E-value: 1.09e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088    67 DVNVGTHGTVAVPKLKAMSSKMRLPLAKGKNIL-HVEFLLNYKPAQQDISNTRATRAEFDRWYDAVKNEYEV-DDTQMTV 144
Cdd:pfam00767   1 DVAAATSITFEVPRRKGFGALWRPPKQKGAATPnRIEKLKKYLPDQNDISNTRATQAQLNDWYEAVRDDYGQtEEEFMDT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088   145 IMSGLMVWCIENGCSPNIN--GVW-----TMMDGEEQRTFPLKPIIENASPTFRQIMHHFSDAAEA-YIEFRNATERYMP 216
Cdd:pfam00767  81 ILPGWIVWCIENGTSPENRkaGSWravimAMMEDEEQVLYPIEPIIINAQPTLRQIMRHFSDLARAqYAESRNQGKPYMP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088   217 RYGLQRNLTDYSLARYAFDFYEITSRTTARAKEAHMQMKAAAVRGSNTRMFGLDGNVGESQENTERHTAGDVSRNMHSLL 296
Cdd:pfam00767 161 KGGLKAGLADASLAAYAFDFYEDTSHDTARAREVHHQMKAAAVSGIKIRLFALAGPGSGQEEDTERHTVEDVAEGIHSLG 240


                  ...
gi 47156088   297 GVQ 299
Cdd:pfam00767 241 GAQ 243
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 11-67 2.72e-07

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 51.35  E-value: 2.72e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 47156088   11 QTEEQKKAAEEQRQKAAADAEAKRKAAADEEARKAREAEAERKRQADAAAKGKQDKD 67
Cdd:PRK09510 126 QAALKQKQAEEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAE 182
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 11-66 9.82e-07

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 49.46  E-value: 9.82e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088    11 QTEEQKKAAEEQRQKAAADAEAKRKAAAD----EEARKAREAEAERKRQADAAAKGKQDK 66
Cdd:TIGR02794 113 QAEEKQKQAEEAKAKQAAEAKAKAEAEAErkakEEAAKQAEEEAKAKAAAEAKKKAEEAK 172
 
Name Accession Description Interval E-value
Poty_coat pfam00767
Potyvirus coat protein;
67-299 1.09e-100

Potyvirus coat protein;


Pssm-ID: 279151  Cd Length: 243  Bit Score: 295.28  E-value: 1.09e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088    67 DVNVGTHGTVAVPKLKAMSSKMRLPLAKGKNIL-HVEFLLNYKPAQQDISNTRATRAEFDRWYDAVKNEYEV-DDTQMTV 144
Cdd:pfam00767   1 DVAAATSITFEVPRRKGFGALWRPPKQKGAATPnRIEKLKKYLPDQNDISNTRATQAQLNDWYEAVRDDYGQtEEEFMDT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088   145 IMSGLMVWCIENGCSPNIN--GVW-----TMMDGEEQRTFPLKPIIENASPTFRQIMHHFSDAAEA-YIEFRNATERYMP 216
Cdd:pfam00767  81 ILPGWIVWCIENGTSPENRkaGSWravimAMMEDEEQVLYPIEPIIINAQPTLRQIMRHFSDLARAqYAESRNQGKPYMP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088   217 RYGLQRNLTDYSLARYAFDFYEITSRTTARAKEAHMQMKAAAVRGSNTRMFGLDGNVGESQENTERHTAGDVSRNMHSLL 296
Cdd:pfam00767 161 KGGLKAGLADASLAAYAFDFYEDTSHDTARAREVHHQMKAAAVSGIKIRLFALAGPGSGQEEDTERHTVEDVAEGIHSLG 240


                  ...
gi 47156088   297 GVQ 299
Cdd:pfam00767 241 GAQ 243
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 11-67 2.72e-07

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 51.35  E-value: 2.72e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 47156088   11 QTEEQKKAAEEQRQKAAADAEAKRKAAADEEARKAREAEAERKRQADAAAKGKQDKD 67
Cdd:PRK09510 126 QAALKQKQAEEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAE 182
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 11-66 9.82e-07

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 49.46  E-value: 9.82e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088    11 QTEEQKKAAEEQRQKAAADAEAKRKAAAD----EEARKAREAEAERKRQADAAAKGKQDK 66
Cdd:TIGR02794 113 QAEEKQKQAEEAKAKQAAEAKAKAEAEAErkakEEAAKQAEEEAKAKAAAEAKKKAEEAK 172
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 13-67 1.28e-06

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 49.42  E-value: 1.28e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 47156088   13 EEQKKAAEEQRQKAAADA----EAKRKAAADEEARKAREAEAERKRQADAAAKGKQDKD 67
Cdd:PRK09510 166 EAKKKAEAEAAKKAAAEAkkkaEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKAAAEAK 224
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 11-66 2.16e-06

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 48.30  E-value: 2.16e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47156088    11 QTEEQKKAAEEQRQKAA----ADAEAKRKAAAdeEARKAREAEAERKRQADAAAKGKQDK 66
Cdd:TIGR02794  99 AAEKAAKQAEQAAKQAEekqkQAEEAKAKQAA--EAKAKAEAEAERKAKEEAAKQAEEEA 156
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 11-68 3.25e-06

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 47.88  E-value: 3.25e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 47156088   11 QTEEQKKAAEEQRQKAAADAEAKRKAAADEEARKAREAEAERKRQADAAAKGKQDKDV 68
Cdd:PRK09510 112 AAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAEAKK 169
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 5-63 3.78e-06

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 47.88  E-value: 3.78e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 47156088    5 DAGTPPQTEEQKKAAEEQRQKAAADAEAKRKAAADEEA-----RKAREAEAERKRQADAAAKGK 63
Cdd:PRK09510 182 EAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKAaaeakAAAAKAAAEAKAAAEKAAAAK 245
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 13-66 1.68e-05

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 45.61  E-value: 1.68e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 47156088    13 EEQKKAAEEQRQKAAAD----AEAKRKAAADEEARKAREAEAerKRQADAAAKGKQDK 66
Cdd:TIGR02794 162 AEAKKKAEEAKKKAEAEakakAEAEAKAKAEEAKAKAEAAKA--KAAAEAAAKAEAEA 217
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 13-66 2.41e-05

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 45.22  E-value: 2.41e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 47156088    13 EEQKKAAEEQRQKAAADAEAKRKAAADEEARKAR-EAEAERKRQADAAAKGKQDK 66
Cdd:TIGR02794 139 EAERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKkKAEAEAKAKAEAEAKAKAEE 193
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 11-65 2.97e-05

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 44.84  E-value: 2.97e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 47156088    11 QTEEQK-KAAEEQRQKAAADAEAKRKAAAD---EEARKAREAEAERKRQADAAAKGKQD 65
Cdd:TIGR02794 120 QAEEAKaKQAAEAKAKAEAEAERKAKEEAAkqaEEEAKAKAAAEAKKKAEEAKKKAEAE 178
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 13-67 1.43e-04

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.87  E-value: 1.43e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 47156088   13 EEQKKAAEEQRQKAAADAEAKRKAAAD----EEARKAREAEAERKRQADAAAKGKQDKD 67
Cdd:PRK09510 150 EAEAKRAAAAAKKAAAEAKKKAEAEAAkkaaAEAKKKAEAEAAAKAAAEAKKKAEAEAK 208
PTZ00121 PTZ00121
MAEBL; Provisional
 11-66 1.45e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 1.45e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 47156088    11 QTEEQKKAAEEQRQKAAA--DAEAKRKAaadEEARKAREA-EAERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAkkKADEAKKA---EEAKKADEAkKAEEAKKADEAKKAEEKK 1546
PTZ00121 PTZ00121
MAEBL; Provisional
 11-66 1.85e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 1.85e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 47156088    11 QTEEQKKAAEEQRQKAAADAEAKRKAAADEEARKAREA--EAERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1399 KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkKAEEAKKADEAKKKAEEA 1456
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 11-67 1.90e-04

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.49  E-value: 1.90e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 47156088   11 QTEEQKKAAEEQRQKAAADAEAKRKAAADEEARKAREAEAERKRQADAAAKGKQDKD 67
Cdd:PRK09510 204 EAEAKKKAAAEAKKKAAAEAKAAAAKAAAEAKAAAEKAAAAKAAEKAAAAKAAAEVD 260
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 13-66 6.14e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 40.98  E-value: 6.14e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 47156088    13 EEQKKAAEEQRQKAAADAEAKRKAA---ADEEARKAreAEAERKRQA-DAAAKGKQDK 66
Cdd:TIGR02794 147 EAAKQAEEEAKAKAAAEAKKKAEEAkkkAEAEAKAK--AEAEAKAKAeEAKAKAEAAK 202
PRK07735 PRK07735
NADH-quinone oxidoreductase subunit C;
3-63 7.37e-04

NADH-quinone oxidoreductase subunit C;


Pssm-ID: 236081 [Multi-domain]  Cd Length: 430  Bit Score: 40.73  E-value: 7.37e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 47156088    3 RVDAGTPPQTEEQKKAAEEQRQKAAADAEAKRKAAADEEARKAREAEAERKRQADAAAKGK 63
Cdd:PRK07735 146 KREGTEEVTEEEEETDKEKAKAKAAAAAKAKAAALAKQKAAEAGEGTEEVTEEEKAKAKAK 206
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 11-65 9.43e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 40.21  E-value: 9.43e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 47156088    11 QTEEQKKAAEEQRQKAAADAEAKRKAAADEEARK--AREAEAERKRQADAAAKGKQD 65
Cdd:TIGR02794 174 KAEAEAKAKAEAEAKAKAEEAKAKAEAAKAKAAAeaAAKAEAEAAAAAAAEAERKAD 230
PTZ00121 PTZ00121
MAEBL; Provisional
 11-66 1.18e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 1.18e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 47156088    11 QTEEQKKAAEEQRQkaaADaEAKRKAaadEEARKAREA--EAERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1432 KADEAKKKAEEAKK---AD-EAKKKA---EEAKKAEEAkkKAEEAKKADEAKKKAEEA 1482
PTZ00121 PTZ00121
MAEBL; Provisional
 12-70 1.27e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 1.27e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 47156088    12 TEEQKKAAEEQRQKAAADAEAKRKAAAD----EEARKAREA-EAERKRQADAAAKGKQDKDVNV 70
Cdd:PTZ00121 1093 TEEAFGKAEEAKKTETGKAEEARKAEEAkkkaEDARKAEEArKAEDARKAEEARKAEDAKRVEI 1156
PTZ00121 PTZ00121
MAEBL; Provisional
 11-68 1.36e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 1.36e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 47156088    11 QTEEQKKAAEEQRQKAAADAEAKRKAaadEEARKAREA-EAERKRQADAAAKGKQDKDV 68
Cdd:PTZ00121 1523 KADEAKKAEEAKKADEAKKAEEKKKA---DELKKAEELkKAEEKKKAEEAKKAEEDKNM 1578
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 11-67 1.89e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 39.40  E-value: 1.89e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 47156088   11 QTEEQKKAAEEQrQKAAADAEAKRKAAAD--EEARKAREAEAERKRQADAAAKGKQDKD 67
Cdd:PRK09510 141 AAAAAKAKAEAE-AKRAAAAAKKAAAEAKkkAEAEAAKKAAAEAKKKAEAEAAAKAAAE 198
PTZ00121 PTZ00121
MAEBL; Provisional
 13-66 2.53e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 2.53e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 47156088    13 EEQKKAAEEQRQKAAADAEAKRKAaadEEARKAREA-EAERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKA---EEAKKADEAkKAEEKKKADELKKAEELK 1558
PRK12472 PRK12472
hypothetical protein; Provisional
 11-59 2.73e-03

hypothetical protein; Provisional


Pssm-ID: 237110 [Multi-domain]  Cd Length: 508  Bit Score: 39.08  E-value: 2.73e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 47156088   11 QTEEQKKAAEEQRQKAA--------------ADAEAKRKA--AADEEARKAREAEAERKRQADAA 59
Cdd:PRK12472 252 KTDEAKARAEERQQKAAqqaaeaatqldtakADAEAKRAAaaATKEAAKAAAAKKAETAKAATDA 316
PTZ00121 PTZ00121
MAEBL; Provisional
 11-66 2.96e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.35  E-value: 2.96e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 47156088    11 QTEEQKKAAEEQRQKAAADAEAKRKAAAD------EEARKAREAEA---ERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAEEAKKADeakkkaEEAKKADEAKKkaeEAKKKADEAKKAAEAK 1509
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 6-67 3.93e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 38.29  E-value: 3.93e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 47156088     6 AGTPPQTEEQKKAAEEQRQKAAADAEA--------KRKAAADEEARKAREA--EAERKRQADAAAKGKQDKD 67
Cdd:TIGR02794  60 KPAAKKEQERQKKLEQQAEEAEKQRAAeqarqkelEQRAAAEKAAKQAEQAakQAEEKQKQAEEAKAKQAAE 131
PTZ00121 PTZ00121
MAEBL; Provisional
 11-66 4.75e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.58  E-value: 4.75e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 47156088    11 QTEEQKKAAEEQRQKAAADA---EAKRKA----AADEEARKAREA-EAERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKKkaeEAKKKAdeakKAAEAKKKADEAkKAEEAKKADEAKKAEEAK 1534
PTZ00121 PTZ00121
MAEBL; Provisional
 11-66 5.05e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.58  E-value: 5.05e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 47156088    11 QTEEQKKAAEEQRQKAAADAEAKRKAAAD------EEARKAREA--EAERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAKKKAEEKKKADeakkkaEEAKKADEAkkKAEEAKKAEEAKKKAEEA 1469
PTZ00121 PTZ00121
MAEBL; Provisional
 11-67 5.27e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.58  E-value: 5.27e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 47156088    11 QTEEQKKAAEEQRQKAaadAEAKRKAaadEEARKAREA-EAERKRQADAAAKGKQDKD 67
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKA---DAAKKKA---EEAKKAAEAaKAEAEAAADEAEAAEEKAE 1367
PTZ00121 PTZ00121
MAEBL; Provisional
 11-66 6.50e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.20  E-value: 6.50e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47156088    11 QTEEQKKAAEEQRQKAAADAEAKRKA----AADEEARKAREAEA---ERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1279 KADELKKAEEKKKADEAKKAEEKKKAdeakKKAEEAKKADEAKKkaeEAKKKADAAKKKAEEA 1341
PTZ00121 PTZ00121
MAEBL; Provisional
 11-66 8.67e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 37.81  E-value: 8.67e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 47156088    11 QTEEQKKAAEEQRQkaaADaEAKRKAaadEEARKAREA---EAERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1303 KADEAKKKAEEAKK---AD-EAKKKA---EEAKKKADAakkKAEEAKKAAEAAKAEAEA 1354
PTZ00121 PTZ00121
MAEBL; Provisional
 11-66 8.90e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 37.81  E-value: 8.90e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 47156088    11 QTEEQKKAAEEQRQKA--------AADAEAKRKA----AADEEARKAREAEAERKRQADAAAKGKQDK 66
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAeeakkaaeAAKAEAEAAAdeaeAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 14-63 8.93e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 37.13  E-value: 8.93e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 47156088    14 EQKKAAEEQRQKA-AADAEAKRKAAADEEARKAREAEAERKRQADAAAKGK 63
Cdd:TIGR02794 186 EAKAKAEEAKAKAeAAKAKAAAEAAAKAEAEAAAAAAAEAERKADEAELGD 236
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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