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cactin [Homo sapiens]
splicing factor cactin( domain architecture ID 10563375)
splicing factor cactin plays a role in pre-mRNA splicing by facilitating excision of a subset of introns
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||
CactinC_cactus | pfam09732 | Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of ... |
634-758 | 9.63e-93 | ||||
Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of the cactin protein which are necessary for the association of cactin with IkappaB-cactus as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Most members of the family also have a Cactin_mid domain pfam10312 further upstream. : Pssm-ID: 401611 Cd Length: 125 Bit Score: 284.87 E-value: 9.63e-93
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Cactin_mid | pfam10312 | Conserved mid region of cactin; This is the conserved middle region of a family of proteins ... |
270-457 | 7.97e-76 | ||||
Conserved mid region of cactin; This is the conserved middle region of a family of proteins referred to as cactins. The region contains two of three predicted coiled-coil domains. Most members of this family have a CactinC_cactus pfam09732 domain at the C-terminal end. Upstream of Mid_cactin in Drosophila members are a serine-rich region, some non-typical RD motifs and three predicted bipartite nuclear localization signals, none of which are well-conserved. Cactin associates with IkappaB-cactus as one of the intracellular members of the Rel (NF-kappaB) pathway which is conserved in invertebrates and vertebrates. In mammals, this pathway controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. : Pssm-ID: 463049 [Multi-domain] Cd Length: 186 Bit Score: 242.85 E-value: 7.97e-76
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PTZ00266 super family | cl31758 | NIMA-related protein kinase; Provisional |
214-272 | 9.68e-03 | ||||
NIMA-related protein kinase; Provisional The actual alignment was detected with superfamily member PTZ00266: Pssm-ID: 173502 [Multi-domain] Cd Length: 1021 Bit Score: 39.34 E-value: 9.68e-03
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Name | Accession | Description | Interval | E-value | ||||
CactinC_cactus | pfam09732 | Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of ... |
634-758 | 9.63e-93 | ||||
Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of the cactin protein which are necessary for the association of cactin with IkappaB-cactus as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Most members of the family also have a Cactin_mid domain pfam10312 further upstream. Pssm-ID: 401611 Cd Length: 125 Bit Score: 284.87 E-value: 9.63e-93
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CactinC_cactus | smart01050 | Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of ... |
634-758 | 9.45e-77 | ||||
Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of the cactin protein which are necessary for the association of cactin with IkappaB-cactus as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Most members of the family also have a Cactin_mid domain further upstream. Pssm-ID: 214996 Cd Length: 129 Bit Score: 243.03 E-value: 9.45e-77
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Cactin_mid | pfam10312 | Conserved mid region of cactin; This is the conserved middle region of a family of proteins ... |
270-457 | 7.97e-76 | ||||
Conserved mid region of cactin; This is the conserved middle region of a family of proteins referred to as cactins. The region contains two of three predicted coiled-coil domains. Most members of this family have a CactinC_cactus pfam09732 domain at the C-terminal end. Upstream of Mid_cactin in Drosophila members are a serine-rich region, some non-typical RD motifs and three predicted bipartite nuclear localization signals, none of which are well-conserved. Cactin associates with IkappaB-cactus as one of the intracellular members of the Rel (NF-kappaB) pathway which is conserved in invertebrates and vertebrates. In mammals, this pathway controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Pssm-ID: 463049 [Multi-domain] Cd Length: 186 Bit Score: 242.85 E-value: 7.97e-76
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PTZ00266 | PTZ00266 | NIMA-related protein kinase; Provisional |
214-272 | 9.68e-03 | ||||
NIMA-related protein kinase; Provisional Pssm-ID: 173502 [Multi-domain] Cd Length: 1021 Bit Score: 39.34 E-value: 9.68e-03
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Name | Accession | Description | Interval | E-value | ||||
CactinC_cactus | pfam09732 | Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of ... |
634-758 | 9.63e-93 | ||||
Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of the cactin protein which are necessary for the association of cactin with IkappaB-cactus as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Most members of the family also have a Cactin_mid domain pfam10312 further upstream. Pssm-ID: 401611 Cd Length: 125 Bit Score: 284.87 E-value: 9.63e-93
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CactinC_cactus | smart01050 | Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of ... |
634-758 | 9.45e-77 | ||||
Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of the cactin protein which are necessary for the association of cactin with IkappaB-cactus as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Most members of the family also have a Cactin_mid domain further upstream. Pssm-ID: 214996 Cd Length: 129 Bit Score: 243.03 E-value: 9.45e-77
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Cactin_mid | pfam10312 | Conserved mid region of cactin; This is the conserved middle region of a family of proteins ... |
270-457 | 7.97e-76 | ||||
Conserved mid region of cactin; This is the conserved middle region of a family of proteins referred to as cactins. The region contains two of three predicted coiled-coil domains. Most members of this family have a CactinC_cactus pfam09732 domain at the C-terminal end. Upstream of Mid_cactin in Drosophila members are a serine-rich region, some non-typical RD motifs and three predicted bipartite nuclear localization signals, none of which are well-conserved. Cactin associates with IkappaB-cactus as one of the intracellular members of the Rel (NF-kappaB) pathway which is conserved in invertebrates and vertebrates. In mammals, this pathway controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Pssm-ID: 463049 [Multi-domain] Cd Length: 186 Bit Score: 242.85 E-value: 7.97e-76
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PTZ00266 | PTZ00266 | NIMA-related protein kinase; Provisional |
214-272 | 9.68e-03 | ||||
NIMA-related protein kinase; Provisional Pssm-ID: 173502 [Multi-domain] Cd Length: 1021 Bit Score: 39.34 E-value: 9.68e-03
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Blast search parameters | ||||
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