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Conserved domains on  [gi|67090248|gb|AAY67502|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Pachyornis australis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-76 3.48e-32

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00124:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 457  Bit Score: 115.29  E-value: 3.48e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 67090248    1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWLHPTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:MTH00124   4 IILPTIMLIPTTLLSKPKFLWTNTTTYSLLIALLSLQWLKPPYYPTKNLTQWLGIDQISAPLLVLSCWLLPLMILA 79
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-76 3.48e-32

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 115.29  E-value: 3.48e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 67090248    1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWLHPTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:MTH00124   4 IILPTIMLIPTTLLSKPKFLWTNTTTYSLLIALLSLQWLKPPYYPTKNLTQWLGIDQISAPLLVLSCWLLPLMILA 79
Oxidored_q5_N pfam01059
NADH-ubiquinone oxidoreductase chain 4, amino terminus;
1-76 1.06e-15

NADH-ubiquinone oxidoreductase chain 4, amino terminus;


Pssm-ID: 366442 [Multi-domain]  Cd Length: 110  Bit Score: 65.62  E-value: 1.06e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 67090248     1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWL-HPTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:pfam01059   4 ILLPTLMLIPLTFLSKPKWLWTTSTLYSLLLALLSLLLLnNPSNFSWSNLSYFLGIDSLSYPLIILSCWLLPLMILA 80
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-76 3.48e-32

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 115.29  E-value: 3.48e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 67090248    1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWLHPTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:MTH00124   4 IILPTIMLIPTTLLSKPKFLWTNTTTYSLLIALLSLQWLKPPYYPTKNLTQWLGIDQISAPLLVLSCWLLPLMILA 79
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-76 3.72e-20

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 81.89  E-value: 3.72e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 67090248    1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWLHPTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:MTH00068   4 IIIPTLMLLPTTWLSPKKWLWTLTTTNSLIIAFLSLMWFNLPSETMNFTNKYFGIDQISSPLLILTCWLLPLMILA 79
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-76 5.98e-19

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 78.78  E-value: 5.98e-19
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 67090248    1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWLHPTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:MTH00110   4 IIIPTIMLIPLTWLSKNNMIWINTTTYSLLISLISLLLLNQPNDNSLNFSLLFFSDSLSTPLLILTTWLLPLMLMA 79
Oxidored_q5_N pfam01059
NADH-ubiquinone oxidoreductase chain 4, amino terminus;
1-76 1.06e-15

NADH-ubiquinone oxidoreductase chain 4, amino terminus;


Pssm-ID: 366442 [Multi-domain]  Cd Length: 110  Bit Score: 65.62  E-value: 1.06e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 67090248     1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWL-HPTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:pfam01059   4 ILLPTLMLIPLTFLSKPKWLWTTSTLYSLLLALLSLLLLnNPSNFSWSNLSYFLGIDSLSYPLIILSCWLLPLMILA 80
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-76 9.79e-15

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 66.90  E-value: 9.79e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 67090248    1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWL-HPTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:MTH00127   4 ILIPTLMLIPTTWLTPAKWLWTTTLAHSLLIALASLTWLkNLSETGWSSLNLYMATDPLSTPLLVLTCWLLPLMILA 80
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-76 3.16e-12

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 59.57  E-value: 3.16e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 67090248    1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWLH-PTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:MTH00206   2 ILIPLIMLLLMTILSKKKWLWRSTTFFSFLIALLFLLWFKwSSEVGWSFSNLYLSYDPLSSPLVILSCWLLPLMFLA 78
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-76 8.35e-08

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 46.89  E-value: 8.35e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 67090248    1 IIIPTIMLLPTALLSPQNLIWTNTTTHSLLIATISLQWLHPTYF-PYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:MTH00044   4 LILLSLGIAITSWIVPKNKLWPISISQSSLISLLSLFLLNNHWSsSWHNLSLSLATDSLSSPLIILSCWLAPLSLLA 80
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-76 1.89e-04

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 37.80  E-value: 1.89e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 67090248    1 IIIPTIMLLPTALLSPQNlIWTNTTTHSLLIATISLQWLHPTYFPYKNLTQWTGIDQISAPLLVLSCWLLPLMLLA 76
Cdd:MTH00014   4 LIMPLISLLLLPLIKYPW-SWALTFSTLLLLSLFTLLNLYPMSAPYSMFTESLSSDMLSAPLITLTLWITALMILA 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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