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Conserved domains on  [gi|69219114|gb|AAZ04156|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Filchnerella rufitibia]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 3.90e-97

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 290.96  E-value: 3.90e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   81 KYPLNWEqqiIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIqNSMFISTIIIMSIAI 160
Cdd:MTH00160  81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI-NNNFIIIIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKFILP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*...
gi 69219114  321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160 317 FLSFISLFGLILSSLLFL 334
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 3.90e-97

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 290.96  E-value: 3.90e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   81 KYPLNWEqqiIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIqNSMFISTIIIMSIAI 160
Cdd:MTH00160  81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI-NNNFIIIIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKFILP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*...
gi 69219114  321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160 317 FLSFISLFGLILSSLLFL 334
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 3.89e-27

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 108.17  E-value: 3.89e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    24 SNSWFGVWMGLEINLLSFIPILA-NNKNMMMNEPSIKYFIVQAMASTMLLFSILII--------------QLKYPLNWEQ 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    89 QIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMML-MTWQKIAPMMVL-------SYCIQNSMFISTIIIMSIAI 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   161 GALGGLNQISLRQLMAYSSISHLGWMIASISI----SETMWEVYFLVYSLLSVIMILLFN-----QSKLFFMNQIYTSEN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGsviyrRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 69219114   232 MNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-293 4.65e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 102.12  E-value: 4.65e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   8 LLFLSSLmmGTVLSVSSNSWFGVWMGLEINLLSFIpILA--NNKNMMMNEPSIKYFIVQAMASTMLLF----------SI 75
Cdd:COG1007 107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSL 183

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  76 LIIQLKYPLNWEQQIIPSMMISSSLLL-----KIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVL---------S 141
Cdd:COG1007 184 NLAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpG 263

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114 142 YCIQNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWM-IASISISETMWE---VYFLVYSLLSV---IMILL 214
Cdd:COG1007 264 LAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGVSaalFYLLAYLFMNLgafAVILL 343

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114 215 FNQSKlffmnqiytSENMNIE-----------IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTT 283
Cdd:COG1007 344 LSRKG---------GEAEEIEdlaglarrsplLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSV 414

                       330
                ....*....|
gi 69219114 284 ITLYYYMRIM 293
Cdd:COG1007 415 ISAYYYLRVV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 1.64e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 95.01  E-value: 1.64e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    17 GTVLSVSSNSWFGVWMGLEI-NLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILII----------QLKYPLN 85
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    86 WEQQIIPSM-----MISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIA---PMMVLSYCIQ------NSMFIS 151
Cdd:TIGR01770 194 NGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   152 TIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWE----VYFLVYSLLSV----IMILLFNQSK---- 219
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlFYIFIYALMSLgafgVLSLLRSYKDewie 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   220 -LFFMNQIYTSenmNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRImfsAMI 298
Cdd:TIGR01770 354 yISDFAGLFKT---NPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKV 427

                         330       340       350
                  ....*....|....*....|....*....|....
gi 69219114   299 MTFSE-NSWSINNNMKSPKFILPTLVTISTLGLI 331
Cdd:TIGR01770 428 MYFDKpERRIPSNPQSKAQSLLLSISALFILFLG 461
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 3.90e-97

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 290.96  E-value: 3.90e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   81 KYPLNWEqqiIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIqNSMFISTIIIMSIAI 160
Cdd:MTH00160  81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI-NNNFIIIIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKFILP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*...
gi 69219114  321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160 317 FLSFISLFGLILSSLLFL 334
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-340 1.07e-66

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 213.17  E-value: 1.07e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSIlIIQLKYPLNWE 87
Cdd:MTH00105   7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAI-IINLMYSGQWT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   88 QQIIP----SMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLsYCIQNSMFISTII---IMSIAI 160
Cdd:MTH00105  86 ITKLTnptaSTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSIL-YQISPSINPNLLLtlaILSILI 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00105 165 GGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLI 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSEnswsiNNNMK------- 313
Cdd:MTH00105 245 LLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPS-----TNNMKmkwqfen 319

                        330       340
                 ....*....|....*....|....*...
gi 69219114  314 -SPKFILPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00105 320 tKPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 6-340 9.00e-65

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 208.52  E-value: 9.00e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    6 TKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSIL--------- 76
Cdd:MTH00112   5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTtnawntgqw 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   77 -IIQLKYPlnweqqiIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLsYCIQNSM---FIST 152
Cdd:MTH00112  85 dITQLTNP-------TSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLL-LMTSNSLnptLLLT 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  153 IIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENM 232
Cdd:MTH00112 157 LAILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTK 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  233 NIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMI-----MTFSENSWS 307
Cdd:MTH00112 237 SPTLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTItlppnTTNMMMKWR 316

                        330       340       350
                 ....*....|....*....|....*....|...
gi 69219114  308 INNNMKSPkfiLPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00112 317 TKPKKNTL---TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 8-340 4.37e-63

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 204.01  E-value: 4.37e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILiIQLKYPLNW- 86
Cdd:MTH00041   7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGAL-IQAWLSGSWs 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   87 ---EQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQ--NSMFISTIIIMSIAIG 161
Cdd:MTH00041  86 ingPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNllNSNILILCGILSVLVG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  162 ALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLMF 241
Cdd:MTH00041 166 GWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFI 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  242 LTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKF---- 317
Cdd:MTH00041 246 LSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNItvyg 325

                        330       340
                 ....*....|....*....|....
gi 69219114  318 -ILPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00041 326 vILSILSSISILGLLLIPLFLSFL 349
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-339 7.21e-60

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 195.79  E-value: 7.21e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    9 LFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSIL----------II 78
Cdd:MTH00135   8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwdIQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   79 QLKYPLnweqqiiPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMmVLSYCIQ--NSMFISTIIIM 156
Cdd:MTH00135  88 QMSHPL-------PTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAptNPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  157 SIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEI 236
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  237 KFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFsAMIMTFSENswsiNNNMKSPK 316
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSY-AMTLTISPN----TLNGTTPW 314

                        330       340
                 ....*....|....*....|...
gi 69219114  317 FILPTLVTIstlgLISTSTMIST 339
Cdd:MTH00135 315 RLPSTQLTL----PLAISTTATL 333
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-340 8.83e-60

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 195.52  E-value: 8.83e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   10 FLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILI---IQLKYPLNW 86
Cdd:MTH00070   9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInawFTGEWTIMN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   87 EQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQ--NSMFISTIIIMSIAIGALG 164
Cdd:MTH00070  89 MQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHllNSNLLIIMGLLSTLIGGWG 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  165 GLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLMFLTL 244
Cdd:MTH00070 169 GLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  245 LSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFsAMIMTFSENS------WSINNNmksPKFI 318
Cdd:MTH00070 249 LSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSY-AMSLTTSPNTsnsklyWRFKNK---TNNL 324

                        330       340
                 ....*....|....*....|..
gi 69219114  319 LPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00070 325 LSLTIILSLMLLPITPTILNLF 346
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 3-320 3.53e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 180.47  E-value: 3.53e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    3 SNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIqlkY 82
Cdd:MTH00144   2 SSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIM---Y 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   83 PLNWEQQIipSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSMFISTIIIMSIA--- 159
Cdd:MTH00144  79 NLSFSWFS--MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVLsal 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  160 IGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIyTSENMNIEIKFL 239
Cdd:MTH00144 157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDL-GSLKPSYKTGLS 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  240 MFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKFIL 319
Cdd:MTH00144 236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSIISL 315


                 .
gi 69219114  320 P 320
Cdd:MTH00144 316 N 316
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-340 1.13e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 179.78  E-value: 1.13e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    6 TKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSIL---IIQLKY 82
Cdd:MTH00200   5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLlnaWTSGQW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   83 PLNWEQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLS--YCIQNSMFISTIIIMSIAI 160
Cdd:MTH00200  85 GISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00200 165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMT--FSENSWSINNNMKSPKFI 318
Cdd:MTH00200 245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLspNQINMMSSWRTKSNSNLL 324

                        330       340
                 ....*....|....*....|..
gi 69219114  319 LPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00200 325 VGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-337 3.17e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 177.94  E-value: 3.17e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    9 LFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQLKYPLnweq 88
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYL---- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   89 QIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSMFISTIIIMSIAIGALGGLNQ 168
Cdd:MTH00197  78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  169 ISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLMFLTLLSLG 248
Cdd:MTH00197 158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  249 GLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTfseNSWSINNNMKSPKFILPTLVTISTL 328
Cdd:MTH00197 238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILS---NWMINFLMKINLLYSGLFILLMMML 314


                 ....*....
gi 69219114  329 GLISTSTMI 337
Cdd:MTH00197 315 PLLMIFTMI 323
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-331 2.51e-49

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 168.03  E-value: 2.51e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSIliiQL 80
Cdd:MTH00011   2 MSTFPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM---TM 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   81 KYPLNWEQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYC--IQNSMFISTIIIMSI 158
Cdd:MTH00011  79 MWSFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  159 AIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKF 238
Cdd:MTH00011 159 LAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSM 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  239 LMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMtfSENSWSINNNMKSPKFI 318
Cdd:MTH00011 239 SLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYL--SPTFSSLKSAPYEPKTK 316

                        330
                 ....*....|...
gi 69219114  319 LPTLVTISTLGLI 331
Cdd:MTH00011 317 ILISMCTLSLGLI 329
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 3.89e-27

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 108.17  E-value: 3.89e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    24 SNSWFGVWMGLEINLLSFIPILA-NNKNMMMNEPSIKYFIVQAMASTMLLFSILII--------------QLKYPLNWEQ 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    89 QIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMML-MTWQKIAPMMVL-------SYCIQNSMFISTIIIMSIAI 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   161 GALGGLNQISLRQLMAYSSISHLGWMIASISI----SETMWEVYFLVYSLLSVIMILLFN-----QSKLFFMNQIYTSEN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGsviyrRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 69219114   232 MNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-319 5.94e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 103.57  E-value: 5.94e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   16 MGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMN-EPSIKYFIVQAMASTMLLF----------SILIIQLKYPL 84
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFgcallcgttgGLHLSYINLVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   85 NWEQQI------IPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSMFISTIIIMSI 158
Cdd:MTH00196  84 NSGQSFssvsvpIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  159 AIGALGGLNQISLRQLMAYSSISHLGWMIASISI-------SETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSEN 231
Cdd:MTH00196 164 FVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfesiqASLVYLFIYIIMSICVFSIILALNVYKNLIIEFSGLSRR 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  232 MNIeIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMfsaMIMTFSENSW--SIN 309
Cdd:MTH00196 244 LPI-LAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV---KILFFQANSFllIST 319

                        330
                 ....*....|
gi 69219114  310 NNMKSPKFIL 319
Cdd:MTH00196 320 KILKKENKIN 329
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-303 3.09e-24

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 102.59  E-value: 3.09e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    8 LLFLSSLMmGTVLSVSSNSWFGVWMGLEI-NLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLF----------SIL 76
Cdd:PRK05777 107 LLVLFALL-GMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygatgSLS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   77 IIQLKYPLNWEQQIIPSM-----MISSSLLLKIGAAPFHFWFPEV-----------MGATSWINCMMLMTwqKIAPMMVL 140
Cdd:PRK05777 186 FAGIAKALADGSGNSLLLlfglvFLLVGLAFKLSAVPFHMWTPDVyegaptpvtafLATAPKIAAFAVLL--RLLVVAFG 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  141 SYCIQNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIM------ILL 214
Cdd:PRK05777 264 GLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMtlgafgVIS 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  215 FNQSKLFFMNQIYTSENMNIE---IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMR 291
Cdd:PRK05777 344 LLRRKGGEAESISDFAGLSKRsplLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423

                        330
                 ....*....|..
gi 69219114  292 IMfsaMIMTFSE 303
Cdd:PRK05777 424 VI---KLMYFDE 432
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-293 4.65e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 102.12  E-value: 4.65e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   8 LLFLSSLmmGTVLSVSSNSWFGVWMGLEINLLSFIpILA--NNKNMMMNEPSIKYFIVQAMASTMLLF----------SI 75
Cdd:COG1007 107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSL 183

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  76 LIIQLKYPLNWEQQIIPSMMISSSLLL-----KIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVL---------S 141
Cdd:COG1007 184 NLAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpG 263

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114 142 YCIQNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWM-IASISISETMWE---VYFLVYSLLSV---IMILL 214
Cdd:COG1007 264 LAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGVSaalFYLLAYLFMNLgafAVILL 343

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114 215 FNQSKlffmnqiytSENMNIE-----------IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTT 283
Cdd:COG1007 344 LSRKG---------GEAEEIEdlaglarrsplLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSV 414

                       330
                ....*....|
gi 69219114 284 ITLYYYMRIM 293
Cdd:COG1007 415 ISAYYYLRVV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 1.64e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 95.01  E-value: 1.64e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    17 GTVLSVSSNSWFGVWMGLEI-NLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILII----------QLKYPLN 85
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    86 WEQQIIPSM-----MISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIA---PMMVLSYCIQ------NSMFIS 151
Cdd:TIGR01770 194 NGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   152 TIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWE----VYFLVYSLLSV----IMILLFNQSK---- 219
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlFYIFIYALMSLgafgVLSLLRSYKDewie 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   220 -LFFMNQIYTSenmNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRImfsAMI 298
Cdd:TIGR01770 354 yISDFAGLFKT---NPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKV 427

                         330       340       350
                  ....*....|....*....|....*....|....
gi 69219114   299 MTFSE-NSWSINNNMKSPKFILPTLVTISTLGLI 331
Cdd:TIGR01770 428 MYFDKpERRIPSNPQSKAQSLLLSISALFILFLG 461
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-292 1.94e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 94.70  E-value: 1.94e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   16 MGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMN-EPSIKYFIVQAMASTMLLFSILiiqLKYPLNWEQQI---- 90
Cdd:MTH00199 108 LGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAYStEAGLKYFVLGAVSSGLFLFGCA---LLYGLTGETSIqgin 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   91 ------IPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIApmmVLSYCIQNSMFISTII---IMSIAIG 161
Cdd:MTH00199 185 siltgdVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIG---VFSILVQIGPVTNVVLicaVLSIIYG 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  162 ALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIM------ILLFNQSKLFFMNQIYTSENMNIE 235
Cdd:MTH00199 262 AIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSFESIQASLIYMIIYVIMsicsfsIILSLKLTKGLIVEVSGLSRKNPV 341

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 69219114  236 IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRI 292
Cdd:MTH00199 342 IALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-293 3.41e-17

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 82.60  E-value: 3.41e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   16 MGTVLSVSSNSWFGVWMGLEINLLSFIpILANNKNMMMNEPS----------IKYFIVQAMASTMLLF------------ 73
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALF-ILAGEGSQPGSHFPspgntppesgLKYWILGAMSSGFYLFgcalyfgftgne 277

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   74 ----SILIIQLKYP-LNWEQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSM 148
Cdd:MTH00198 278 gmlgTILSATLETTnIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSK 357

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  149 FISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISI-------SETMWEVYFLVYSLLSVIMILLFN----- 216
Cdd:MTH00198 358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAgtyeslqASWTYAVTYLVSALASFTVICTLEefgtr 437

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  217 -------QSKLFFMNQIYTSENMNI------EIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAI------ 277
Cdd:MTH00198 438 tptsrqrDGSFGNYNLVRRLVDLTIlsrgqpYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSSLSIyylval 517

                        330
                 ....*....|....*..
gi 69219114  278 -MTVLTTITLYYYMRIM 293
Cdd:MTH00198 518 fAIICTCISAFYYIRIV 534
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-296 3.47e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 79.04  E-value: 3.47e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  10 FLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQLKYP-LNWEQ 88
Cdd:COG0651 112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGtLNMAD 191

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  89 ------------QIIPSMMISSSLLLKIGAAPFHFWFPEVMG-ATSWINCMM--LMTwqKIAP-----MMVLSYCIQNSM 148
Cdd:COG0651 192 laarlaeldpglLLAAFALLLVGFGIKAALFPLHFWLPDAYPaAPSPVSALLsgLLT--KVGVyailrVLTLLFGADPAL 269

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114 149 FISTIII----MSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISIsetmwevyFLVYSLLSVIMILL---FNQSKLF 221
Cdd:COG0651 270 FLGTLLLvlglLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGL--------GTPLGLAGALFHLLnhaLAKALLF 341

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114 222 F----MNQIYTSENMNIE---------IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYY 288
Cdd:COG0651 342 LaagaIERATGTRDLDKLgglgkrmplTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAY 421


                ....*...
gi 69219114 289 YMRIMFSA 296
Cdd:COG0651 422 FVRIFGRA 429
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-296 1.75e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 58.96  E-value: 1.75e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   55 EPSIKYFIVQAMASTMLLFSILIIQLKY-PLN------------WEQQIIPSMMISSSLLLKIGAAPFHFWFPEVMG-AT 120
Cdd:PRK08376 172 EAGIKYMFVGSLASSMVLLGIALLYGQYgTLNmaylavkmsenpTVVAKIALALFIAGLAMKSGAVPVHMWLPDAYPaAP 251

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  121 SWINCMMLMTWQ-KIAPMMVLSYCIQ----NSMFISTIII----MSIAIGALGGLNQISLRQLMAYSSISHLGWMIASIS 191
Cdd:PRK08376 252 SSISAMLLVIKQaGLYALARVLFSIYgpaiNLATVGWVIIilgcLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGLG 331

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  192 I------SETMWEV--------------YFLVYSLLSVIMILLFNQSKLFFMNQIY-TSENMNIEIKFLMfLTLLSLGGL 250
Cdd:PRK08376 332 VglaalgDPAMASYgeialaggiyhivnHALYKALLFLTAGAVIYETGTRNLNELGgLARTMPKTTIAFL-IGAAAIVGL 410

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 69219114  251 PPFLGFMPKWMVMQSMVENNlSALMAIMTVLTTITLYYYMRIMFSA 296
Cdd:PRK08376 411 PPFNGFASKWLIYESSALFN-PILGVIAMIGSVLTLASFVKVFHTA 455
PRK12650 PRK12650
DUF4040 family protein;
94-298 1.78e-08

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 55.82  E-value: 1.78e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   94 MMISSSLLLKIGAAPFHFWFPEVMGATSWINCMM---LMTWQKIAPMMVLSYCIQNSMFISTIII---MSIAI-GALGGL 166
Cdd:PRK12650 212 VLIAVAAFTKSAQFPFHFWLPEAMAAITPVSAFLhaaAVVKAGIYLLLRFSPVFHDVAVWNWLLIivgMITALmGAVFAV 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  167 NQISLRQLMAYSSISHLGWMIASISISETmwevYFLVYSLLSVIMILLFnQSKLFFMNQIYTSENMNIEIKFL------- 239
Cdd:PRK12650 292 QKTDLKKLTAYSTVSQLGWIVATIGVGTP----FALTAAVVHTLAHALF-KSSLFMLIGVVDHQAGTRDIRRLgslwrrm 366

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  240 ------MFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSA-----LMAIMTVLTTITLYYYMRIMFSAMI 298
Cdd:PRK12650 367 pftfvsVTIAALSMAAVPPLFGFVSKEGMLTAFLEAPGGNagvvlLLVGAALGAVFTFAYSARLVLGAFV 436
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-295 3.68e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 54.59  E-value: 3.68e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   55 EPSIKYFIVQAMASTMLLFSILIIQLKY---------PLNWEQQIIPSMMISSSLLLKIGAA---------------PFH 110
Cdd:PRK12667 164 EAAIKYALIGAVGTTLYFLALAFLYATFgtlnmadlsAKIRGLSFPLTGGLAGNPPLALGVAlalalwaftikaaifPNH 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  111 FWFPEVM-GATSWINCMMLMTWQK-----IAPMMVLSYCIQNS------MFISTIIIM---SIAIGALGGLNQISLRQLM 175
Cdd:PRK12667 244 FWLPDAHpAAPSPVSAMLSGLVVNvgayaIIRFLYTIFGISPSlidfraALSPILIILgavSAIIGALMMVVQKDVKRLL 323

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  176 AYSSISHLGWMIASISISETMWEVYFLVYSLL-SVIMILLFNQSKLFF-------MNQIYTSENMNIEIKFLMFLTLLSL 247
Cdd:PRK12667 324 AYSTISHMGYIFMGIGIGTQLGLAAALFHIINhAIAKSLLFLASGVFIhaagtrdIDELAGLGRKMPIASFAFLIGALSL 403

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 69219114  248 GGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFS 295
Cdd:PRK12667 404 VGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
147-296 7.77e-08

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 53.80  E-value: 7.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  147 SMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISI---SETMWEVYFLVYS--------LLSVIMILLF 215
Cdd:PRK12663 272 HPLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILLGLALgtpAGINGAIFYLVHDmvvktalfLIAGSLVRLT 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  216 NQSKLFFMNQIYTSENMnieIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFS 295
Cdd:PRK12663 352 GYRSLQYLGGLYRKEPL---FGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRIFFL 428


                 .
gi 69219114  296 A 296
Cdd:PRK12663 429 A 429
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
54-292 1.83e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 52.36  E-value: 1.83e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   54 NEPSIKYFIVQAMASTMLLFSIliiQLKYPLNWEQ----QIIPSMMISSSLLL-------------KIGAAPFHFWFPEV 116
Cdd:PRK02504 160 NEAALKYLLIGAASSAIFLYGS---SLLYGLSGGStqlsAIALALITSPSLGLalalvfviagiafKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  117 MGATSWINCMMLMTWQKIA----PMMVLSYCI-----QNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGW-M 186
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFpsfdeQWKLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFvM 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  187 IASISISETMWE---VYFLVY---SLLSVIMILLFnqSKLFFMNQIYTSENMNIEIKFLMF---LTLLSLGGLPPFLGFM 257
Cdd:PRK02504 317 IGLVAGTEAGYAsmvFYLLAYlfmNLGAFACVILF--SLRTGTDQISDYAGLYQKDPLLTLglsLCLLSLGGIPPLAGFF 394

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 69219114  258 PKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRI 292
Cdd:PRK02504 395 GKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRV 429
ndhB CHL00049
NADH dehydrogenase subunit 2
 8-315 1.01e-06

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 50.00  E-value: 1.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    8 LLFLSSLMMGTVLSVSSNSWFGVWMGLE-INLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLL--FSILI------I 78
Cdd:CHL00049 114 LLFVLTATLGGMFLCGANDLITIFVALEcLSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVygFSWLYglsggeI 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   79 QLKYPLN--WEQQIIPSMMISSSLLL-------KIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMM--------VLS 141
Cdd:CHL00049 194 ELQEIVNglINTQMYNSPGISIALIFitvgigfKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASAlatrifdiPFY 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  142 YCIQNSMFISTII-IMSIAIGALGGLNQISLRQLMAYSSISHLGW-MIASISISETMWEVYFLVYSLLSVIMIL-LFNQS 218
Cdd:CHL00049 274 FSSNEWHLLLEILaILSMILGNLIAITQTSMKRMLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFYIFMNLgTFACI 353

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  219 KLFFM----NQIYTSENMNIEIKFLMF---LTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMR 291
Cdd:CHL00049 354 VLFGLrtgtDNIRDYAGLYTKDPFLALslaLCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLK 433

                        330       340
                 ....*....|....*....|....
gi 69219114  292 IMFSAMIMTFSENSWSINNNMKSP 315
Cdd:CHL00049 434 IIKLLMTGRNQEITPYVRNYRRSP 457
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-292 1.43e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 49.49  E-value: 1.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   34 LEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSI-LIIQLKYPLNWE--QQIIPSM--------MISSSLLL 102
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVgLLYGVTGTLNMAdlAGALAENptvvtafgFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  103 KIGAAPFHFWFPEVMGATS--------------WINCMMLMTWQ--KIAPMMVLSYCIqnsmFISTIIIMSIAIGALGGL 166
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAAPpvvtallsglvtkvAVYALIRIYFTvfGGDFRFALGLGW----LLAVLALLSMLVGSLAAL 290

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  167 NQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMIllfnqSKLFF----MNQIYTSENMN--------I 234
Cdd:PRK08375 291 GQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLHHALMK-----GALFLaagaIEVTYGTRRLSelsglgrrM 365

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 69219114  235 EIKFLMFLTL-LSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRI 292
Cdd:PRK08375 366 PLTAAAFAVAsLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRI 424
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 14-312 4.06e-05

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 44.48  E-value: 4.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   14 LMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNepsikYFIVQAMASTMLLFSILIIQLkyplnweqqiips 93
Cdd:MTH00091   3 LSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLFNY-----FVLQESLGLLFLLFSFGYFQF------------- 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   94 mmisSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSMFIstIIIMSIAIGALGGLNQISLRQ 173
Cdd:MTH00091  65 ----LILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFF--LLLFGLLICFFQMFLLKSYKN 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  174 LMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFnqsklffmnqiytseNMNIEIKFLMFLTLLSLGGLPPF 253
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKF---------------NNVNKLNFVSWETLLVFMNLPFS 203

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 69219114  254 LGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNM 312
Cdd:MTH00091 204 VTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFFF 262
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 95-297 8.73e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 44.17  E-value: 8.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   95 MISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNS----MFISTIIIMSIAIGALGGLNQIS 170
Cdd:PRK07234 189 LIALGLLVKGGIFVSGLWLPLTHSEAEPPVSALLSGVVVKAGVFPLVRCALDVpgldLIVRIFGVGTALLGVLFALLEKD 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  171 LRQLMAYSSISHLGWMIASISISEtmwevyflVYSLLSVIMillfnQSKLFFMNQIYTSEN------MNIEIKFLMFLTL 244
Cdd:PRK07234 269 LKRMLAFSTISQLGFILAAPLVGG--------LYALAHGLV-----KSTLFLCAGALPSRNftelisQMLGIGKWIPLTM 335

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 69219114  245 --LSLGGLPPFLGFMPKWMVMQSMVEnNLSALMAIMTVLTTITLYYYMRIMFSAM 297
Cdd:PRK07234 336 asFSIAGFPLLAGFVSKVLTLKNLLP-WQAIALNLAAVGTAASFWKFIFLPFSAD 389
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 160-292 1.01e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 43.80  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  160 IGALGGLNQISLRQLMAYSSISHLGWMIASISISETMW---EVYFLVYSLLSvimillfnQSKLFFMNQIYTSENMNIEI 236
Cdd:PRK12665 286 VGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAGlsgAIYYVAHHITV--------QTTLFLVVGLIERQAGSSSL 357

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 69219114  237 K-------------FLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLS---ALMAIMTVLTTITLYYYMRI 292
Cdd:PRK12665 358 RrlgglakaspllaVLFFVPALNLGGIPPFSGFIGKVALLEAGAEDGTWlawALVAGGVVTSLLTLYAVARV 429
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 57-293 2.07e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 43.06  E-value: 2.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   57 SIKYFIVQAMASTMLLFSILIIQLKYPLNWEQQIIPSMMISSSL--------------LLKIGAAPFHFWFPEV------ 116
Cdd:PRK08668 149 SLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADISQGLINDTSTgfalivflfllafgVAKAGIFPLHVWAPDAyseapq 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  117 ------------MGATSWINCMMLMTWQKIAPMMVLsycIQNSMFISTIII----MSIAIGALGGLNQISLRQLMAYSSI 180
Cdd:PRK08668 229 sfsavlsgqlskLGAYGFLLVLYVLPGTKLFSEFGT---YRGVPLFNYILAwlgnISIIVGTLMAILQEDIKKLIAYSSV 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  181 SHLGWMIASISISETmwevYFLVYSLLSVIMILLFnqSKLFFMNQ---IYTSENMNIE----------IKFLMFL-TLLS 246
Cdd:PRK08668 306 ANGGYILVGLGLGTS----LGFAGGLFHVFNHALF--KGLFFLIFaavIYRTGTTKISemggliekmpFTFAMYLvAIIS 379

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 69219114  247 LGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIM 293
Cdd:PRK08668 380 LAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPL 426
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 3-305 2.10e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 42.88  E-value: 2.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114    3 SNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFS--ILIIQL 80
Cdd:PRK06589 114 SSSRFLFFFNLTILIGVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPavILIYTK 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   81 KYPLNWEQQII----PSMMISSSLLLKIGAA---PFHFWFPEVMGATSWINCMM---------LMTWQKIAPMM----VL 140
Cdd:PRK06589 194 TGNLDFVSGGLfsknQSIILLLMFIYGIAKTaifPVHSWLPAAMVAHYPVSALLhavivvktgLFCIYKILLYIfglsYL 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  141 SYCIQNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISI----SETMWEVYFLVYSL----LSVIMI 212
Cdd:PRK06589 274 QRIFAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFIltpkALGAAILHLVSHSFakicLFYSMG 353

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  213 LLFNQSKLFFMNQIYTSENMNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVL----TTITLYY 288
Cdd:PRK06589 354 SIYSLKKEDQVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMLVviasSILSALY 433

                        330
                 ....*....|....*..
gi 69219114  289 YMRIMFSAMIMTFSENS 305
Cdd:PRK06589 434 LLKILSSIYKPSLSENS 450
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 8-301 3.76e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 42.06  E-value: 3.76e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   8 LLFLSSlMMGTVLSvssNSWFGVWMGLEI-NLLSFIPILANNKNMMMNEPSIKYFIVQAMASTMLLFSILII-------Q 79
Cdd:COG1009 118 LLFMAA-MLGLVLS---DNLLLLFVFWELvGLCSYLLIGFWYEKPSARRAARKAFLVTRVGDLGLLLGILLLgaiagtlN 193

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  80 LKYPLNWEQQIIPSMMISSSLLLKIGAA-------PFHFWFPEVM-----------GATswincM------MLMtwqKIA 135
Cdd:COG1009 194 FSELLAAAPTILSSPLLTLILLLLLLGAfgksaqfPLHFWLPDAMegptpvsallhAAT-----MvkagvyLLA---RLS 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114 136 PMMVLSYCIQnsMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVY-----SLL--- 207
Cdd:COG1009 266 PLFALSPVWL--TVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVGAYVAALFHLLThaffkALLflg 343

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114 208 --SVIMIL----LFNQSKLF-FMNQIYTsenmnieikfLMFLTLLSLGGLPPFLGFMPKWMVMQSMVE-NNLSALMAIMT 279
Cdd:COG1009 344 agSVIHATgtrdIRKMGGLRkKMPITAI----------TFLIGALSLAGIPPFAGFFSKEAILEAALEaGGLGPLLLAVA 413

                       330       340
                ....*....|....*....|...
gi 69219114 280 VLT-TITLYYYMRIMFsamiMTF 301
Cdd:COG1009 414 LLGaFLTAFYSFRLFF----LVF 432
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 84-222 6.87e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 38.20  E-value: 6.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114   84 LNWEQQIIPSMMISSSLLL------------KIGAAPFHFWFPEVMG-ATSWINCMMLMTWQKIAPMMVLSYCI------ 144
Cdd:PRK08676 188 LNWTELAAHASLLSPSVLGasflfifigflaKSGLVPFHTWLPAAYAkAPSVVSALLSGTVLNIGIYGILRLSAllrqsg 267

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 69219114  145 ---QNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMillfnQSKLF 221
Cdd:PRK08676 268 aaeQFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLAHSLV-----KSGLF 342


                 .
gi 69219114  222 F 222
Cdd:PRK08676 343 F 343
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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