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Conserved domains on  [gi|75677819|gb|ABA19305|]
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ATP synthase subunit 6 (mitochondrion) [Cyanopsitta spixii]

Protein Classification

ATP synthase F0 subunit 6( domain architecture ID 10009577)

ATP synthase F0 subunit 6 is part of the mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-227 6.78e-107

ATP synthase F0 subunit 6; Provisional


:

Pssm-ID: 177190  Cd Length: 227  Bit Score: 307.19  E-value: 6.78e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    1 MILTFFDQFSSPYLLGVPLIFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   81 LMINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 75677819  161 LTANLTAGHLLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-227 6.78e-107

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 307.19  E-value: 6.78e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    1 MILTFFDQFSSPYLLGVPLIFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   81 LMINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 75677819  161 LTANLTAGHLLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 19-227 1.30e-45

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 151.20  E-value: 1.30e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    19 LIFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLLLMINLLGLLPYTFTPTTQ 98
Cdd:TIGR01131  20 LILLLSLLIFLISSSLSRWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILISNLLGLIPYSFTPTSH 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    99 LSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGHLLIQLISTA 178
Cdd:TIGR01131 100 LSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLFANISAGHLLLTLLSGL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 75677819   179 TITLlpIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:TIGR01131 180 LFSL--MSSAIFALLLLILVALIILEIFVAFIQAYVFTLLTCLYLNDAL 226
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 90-224 5.22e-36

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 124.43  E-value: 5.22e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819  90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGH 169
Cdd:cd00310  25 PYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPIELISELIRPLSLSVRLFANMFAGH 104

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 75677819 170 LLIQLISTATITLLPIMPAVSILtatVLFLLTILEVAVAMIQAYVFVLLLSLYLQ 224
Cdd:cd00310 105 LLLALLSGLVPSLLSSVGLLPLL---LPVALTLLELFVAFIQAYVFTLLTAVYIS 156
ATP-synt_A pfam00119
ATP synthase A chain;
90-224 2.67e-31

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 114.12  E-value: 2.67e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTIS-LGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAG 168
Cdd:pfam00119  81 PGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAG 160

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 75677819   169 HLLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQ 224
Cdd:pfam00119 161 HLLLLLLAGLIFALLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 90-225 4.40e-20

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 84.35  E-value: 4.40e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819  90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTIS-LGHLLPEGTPtPLIPALIVIETISLLIRPLALGVRLTANLTAG 168
Cdd:COG0356  78 PGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFP-WLAPLMLPIEIISELARPLSLSLRLFGNMFAG 156

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 75677819 169 HLLIqlistATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQE 225
Cdd:COG0356 157 HIIL-----LLLAGLAPFLLLGVLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISL 208
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-227 6.78e-107

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 307.19  E-value: 6.78e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    1 MILTFFDQFSSPYLLGVPLIFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   81 LMINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 75677819  161 LTANLTAGHLLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-227 6.97e-105

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 302.13  E-value: 6.97e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    1 MILTFFDQFSSPYLLGVPLIFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   81 LMINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 75677819  161 LTANLTAGHLLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:MTH00120 161 LTANLTAGHLLIQLISTATLNLLPTMPTLSLLTLIILLLLTILELAVAMIQAYVFVLLLSLYLQENT 227
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-227 1.07e-100

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 291.49  E-value: 1.07e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    1 MILTFFDQFSSPYLLGVPLIFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLL 80
Cdd:MTH00073   1 MNLSFFDQFLSPTLLGIPLIMLAMLLPWLLFPTPTNKWLNNRLSTLQIWFLQNFTKQLMLPLNTPGHKWALILTSLMVFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   81 LMINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVR 160
Cdd:MTH00073  81 ITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 75677819  161 LTANLTAGHLLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:MTH00073 161 LTANLTAGHLLIQLISTATLVLLPLMPTVSILTMIVLFLLTLLEIAVAMIQAYVFVLLLSLYLQENV 227
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-226 2.44e-83

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 247.55  E-value: 2.44e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    1 MILTFFDQFSSPYLLGVPLIFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLL 80
Cdd:MTH00179   1 MMLSMFDQFESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQSWFFGSFTFQLMQPINKKGHKWAVLFLSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   81 LMINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVR 160
Cdd:MTH00179  81 LTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 75677819  161 LTANLTAGHLLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQEN 226
Cdd:MTH00179 161 LTANITAGHLLMHLISSAVFVLMNFMGMVALLTLLVLFLLTLLEVAVAMIQAYVFVLLLSLYLQEN 226
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 6-226 1.46e-70

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 214.82  E-value: 1.46e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    6 FDQFSSPYLLGVPlIFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLLLMINL 85
Cdd:MTH00101   6 FASFITPTILGLP-IVTLIIMFPSLLFPTPNRLINNRLISIQQWLIQLTSKQMMTIHNTKGQTWSLMLMSLILFIGSTNL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   86 LGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANL 165
Cdd:MTH00101  85 LGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVRLTANI 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75677819  166 TAGHLLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQEN 226
Cdd:MTH00101 165 TAGHLLIHLIGGATLALMSISTTTALITFIILILLTILEFAVALIQAYVFTLLVSLYLHDN 225
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 19-227 1.30e-45

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 151.20  E-value: 1.30e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    19 LIFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLLLMINLLGLLPYTFTPTTQ 98
Cdd:TIGR01131  20 LILLLSLLIFLISSSLSRWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILISNLLGLIPYSFTPTSH 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    99 LSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGHLLIQLISTA 178
Cdd:TIGR01131 100 LSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLFANISAGHLLLTLLSGL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 75677819   179 TITLlpIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:TIGR01131 180 LFSL--MSSAIFALLLLILVALIILEIFVAFIQAYVFTLLTCLYLNDAL 226
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 6-227 4.06e-43

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 145.12  E-value: 4.06e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    6 FDQFSSPYLLGVPL-IFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLLLMIN 84
Cdd:MTH00035   8 FGQFSPDTILFIPLtLLSSVIALSWLFFINPTNWLPSRSQSIWLTFRQEILKLIFQNTNPNTAPWAGLLTTVFILILSIN 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   85 LLGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTAN 164
Cdd:MTH00035  88 VLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPIALGLRLAAN 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 75677819  165 LTAGHLLIQLISTAtITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:MTH00035 168 LTAGHLLIFLLSTA-IWELSNSPLISIITLIIFFLLFILEIGVACIQAYVFTALVHFYLEQNI 229
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 90-225 4.66e-41

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 139.53  E-value: 4.66e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGH 169
Cdd:MTH00157  89 PYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAVRLAANMIAGH 168

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 75677819  170 LLIQLISTATITLLPIMPAVSILTatvLFLLTILEVAVAMIQAYVFVLLLSLYLQE 225
Cdd:MTH00157 169 LLLTLLGNTGPSLSSMILSILILI---QILLLILESAVAIIQSYVFSVLSTLYSSE 221
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 90-226 1.75e-36

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 127.84  E-value: 1.75e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGH 169
Cdd:MTH00176  92 PYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLTLAVRLAANLSAGH 171

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 75677819  170 LLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQEN 226
Cdd:MTH00176 172 LLLGLLGAAMWGLLPVSPLIGFLLLIVQILYFMFEIAVCMIQAYVFTLLLSLYLDEH 228
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 90-224 5.22e-36

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 124.43  E-value: 5.22e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819  90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGH 169
Cdd:cd00310  25 PYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPIELISELIRPLSLSVRLFANMFAGH 104

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 75677819 170 LLIQLISTATITLLPIMPAVSILtatVLFLLTILEVAVAMIQAYVFVLLLSLYLQ 224
Cdd:cd00310 105 LLLALLSGLVPSLLSSVGLLPLL---LPVALTLLELFVAFIQAYVFTLLTAVYIS 156
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 38-225 2.81e-33

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 119.59  E-value: 2.81e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   38 WITNRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLLLMINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLTG 117
Cdd:MTH00173  40 VSSSNLSSVFKLFVLTVSSQVTRSSGLNLGGFSLLLSSLFLFLISLNLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSG 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819  118 LRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGHLLIQLISTATITLLPIMPAVSILTATVL 197
Cdd:MTH00173 120 LFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTLTVRLLANISAGHIVLTLIGNYLSSSLFSSSVVSLLLVLLI 199

                        170       180
                 ....*....|....*....|....*....
gi 75677819  198 FLL-TILEVAVAMIQAYVFVLLLSLYLQE 225
Cdd:MTH00173 200 QVGyFIFEVAVMLIQAYIFTLLIKLYSDE 228
ATP-synt_A pfam00119
ATP synthase A chain;
90-224 2.67e-31

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 114.12  E-value: 2.67e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTIS-LGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAG 168
Cdd:pfam00119  81 PGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAG 160

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 75677819   169 HLLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQ 224
Cdd:pfam00119 161 HLLLLLLAGLIFALLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 38-222 7.43e-28

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 105.59  E-value: 7.43e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   38 WIT-NRLSTLQLWTINTITKQLMTPLNKPGHKWAIVLTSLMMLLLMINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLT 116
Cdd:MTH00005  41 WITpNRLSSIMSPPKSTMHTQLSRTFGKHLKGFSSLISALFTMIILMNLSGLLPYVFSTSSHLIFTLTLGLPLWLSLIMS 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819  117 GLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGHLLIQLISTATITLLPIMPAVSILTATV 196
Cdd:MTH00005 121 SVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISILVRPITLSFRLAANMSAGHIVLSLIGIYAASALFSSISSTILLILT 200

                        170       180
                 ....*....|....*....|....*.
gi 75677819  197 LFLLTILEVAVAMIQAYVFVLLLSLY 222
Cdd:MTH00005 201 QMGYILFEVGICLIQAYIFCLLLSLY 226
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 1-227 4.78e-26

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 101.24  E-value: 4.78e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819    1 MILTFFDQFSSPYLLGVPL-------------IFLSMLLPTLLLPMPGNRWITNRLSTLQLWTINTITKQLMTPLNKPGH 67
Cdd:MTH00175   1 MLAAYFDQFNIIRLITIQAflgdwlvtftnssMMMVLAVIIFWLLLKGDKLIPNRWQSIMELIYLNIRSVVHDNLGKSGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   68 KWAIVLTSLMMLLLMINLLGLLPYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIET 147
Cdd:MTH00175  81 KYFPFILSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLVLIET 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819  148 ISLLIRPLALGVRLTANLTAGHLLIQLISTATITLLPI-MPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQEN 226
Cdd:MTH00175 161 LSYLIRAISLGVRLAANISAGHLLFAILSGFAFNMLSNgLIILSLFPMLIMIFITLLEMAVAVIQAYVFCLLTTIYLGDT 240


                 .
gi 75677819  227 I 227
Cdd:MTH00175 241 I 241
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 90-227 4.29e-25

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 98.19  E-value: 4.29e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGH 169
Cdd:MTH00172  92 PYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPSGAPLGLAPLLVLIETVSYISRAISLGVRLAANLSAGH 171

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 75677819  170 LLIQLISTATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:MTH00172 172 LLFAILAGFGFNMLCASGFLSLFPLLIMVFITLLEIAVAVIQAYVFCLLTTIYLADTI 229
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 90-225 4.40e-20

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 84.35  E-value: 4.40e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819  90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTIS-LGHLLPEGTPtPLIPALIVIETISLLIRPLALGVRLTANLTAG 168
Cdd:COG0356  78 PGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFP-WLAPLMLPIEIISELARPLSLSLRLFGNMFAG 156

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 75677819 169 HLLIqlistATITLLPIMPAVSILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQE 225
Cdd:COG0356 157 HIIL-----LLLAGLAPFLLLGVLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISL 208
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 91-225 3.94e-18

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 79.45  E-value: 3.94e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   91 YTFTPTTQLSMNMALAFPLWLATLLTGLRNQptiSLGHLLPEGTPTPlIPALIVIETISLLIRPLALGVRLTANLTAGHL 170
Cdd:PRK05815  95 LLFPPTADINVTLALALIVFVLVIYYGIKKK---GLGGYLKEFYLQP-HPLLLPIEIISEFSRPISLSLRLFGNMLAGEL 170

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 75677819  171 LIQLISTATITLLPIMPAVSILTatvlFLLTILEVAVAMIQAYVFVLLLSLYLQE 225
Cdd:PRK05815 171 ILALIALLGGAGLLLALAPLILP----VAWTIFEIFVGTLQAYIFMMLTIVYISM 221
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 90-227 1.08e-17

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 79.21  E-value: 1.08e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGH 169
Cdd:MTH00174 111 PYVFTPTVHMVITLGLSFAIIVGTTLAGLITFRFNFFSILMPQGAPLALAPLLTIIETLSYISRAISLGVRLAANISSGH 190

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 75677819  170 LLIQLISTATITLLPIMPAV-SILTATVLFLLTILEVAVAMIQAYVFVLLLSLYLQENI 227
Cdd:MTH00174 191 LLFSIIASFAWKMINTGILIgSFVPFAILIFVTILEMAVAIIQAYVFTLLTIVYLRDTV 249
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 90-225 6.20e-12

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 62.30  E-value: 6.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISlgHLLPEGTPTPLIP-ALIVIETISLLIRPLALGVRLTANLTAG 168
Cdd:MTH00087  72 PYSFSPCGMVEFTFLYALVAWLSTFLSFLSKSEKFS--VYLSKGSDSFLKTfSMLFVEIVSELSRPLALTLRLTVNLMVG 149

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 75677819  169 HLLIQLISTATITLLpimpavsiltatVLFLLTIL-EVAVAMIQAYVFVLLLSLYLQE 225
Cdd:MTH00087 150 HLISSLLNFLGEKYV------------WLSILAIMmECFVAFIQSYIFSRLIYLYLNE 195
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 90-223 1.58e-11

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 62.84  E-value: 1.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGH 169
Cdd:PRK13419 191 PYGATATGNINVTLTLAVFTFFITQYAAIKAHGIKGYLAHLTGGTHWSLWIIMIPIEFIGLFTKPFALTVRLFANMTAGH 270

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 75677819  170 LLI-QLISTATITLLPIM-PAVSILTATVLFLltiLEVAVAMIQAYVFVLLLSLYL 223
Cdd:PRK13419 271 IVIlSLIFISFILKSYIVaVAVSVPFAIFIYL---LELFVAFLQAYIFTMLSALFI 323
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 94-223 2.28e-10

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 59.52  E-value: 2.28e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   94 TPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETI-SLLIRPLALGVRLTANLTAGHLLI 172
Cdd:PRK13417 217 TVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEFIvSPMAKTFALTVRLLANMTAGHVII 296

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 75677819  173 -QLISTATITLLPIMPAVSILTATVLFlltILEVAVAMIQAYVFVLLLSLYL 223
Cdd:PRK13417 297 lALMGFIFQFQSWGIVPVSVIGSGLIY---VLEIFVAFLQAYIFVLLTSLFV 345
ATP6 MTH00050
ATP synthase F0 subunit 6; Validated
 90-220 3.20e-03

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177125  Cd Length: 170  Bit Score: 37.17  E-value: 3.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75677819   90 PYTFTPTTQLSMNMALAFPLWLATLLTGLRNQPTISLGHLLPEGTPTPLIPALIVIETISLLIRPLALGVRLTANLTAGH 169
Cdd:MTH00050  43 PYIYSPFLFVVFLFVVVFPLFISLFLSRVFDSLNEFFSSFVPVGTPLYICPFVCIAETISYIIRPVVLILRPFINISLGC 122

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 75677819  170 LLIQLISTATItllpimpaVSILTATVLFLLTILEVAVAMIQAYVFVLLLS 220
Cdd:MTH00050 123 FGGVALGNLCF--------ISYWWFLVLFFLFFYEVFVALVHWFIVSSILS 165
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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