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Conserved domains on  [gi|125491754|gb|ABN43280|]
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von Willebrand factor, partial [Microcebus tavaratra]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VWD super family cl47498
von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is ...
 2-41 1.14e-07

von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.


The actual alignment was detected with superfamily member pfam00094:

Pssm-ID: 459671 [Multi-domain]  Cd Length: 154  Bit Score: 44.28  E-value: 1.14e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 125491754    2 CQYLLARDC-EDHSFSIVIETVQCADDPDAVCTRSVTVRLP 41
Cdd:pfam00094  23 CTYVLAKDCsEEPDFSFSVTNKNCNGGASGVCLKSVTVIVG 63
 
Name Accession Description Interval E-value
VWD pfam00094
von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is ...
 2-41 1.14e-07

von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.


Pssm-ID: 459671 [Multi-domain]  Cd Length: 154  Bit Score: 44.28  E-value: 1.14e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 125491754    2 CQYLLARDC-EDHSFSIVIETVQCADDPDAVCTRSVTVRLP 41
Cdd:pfam00094  23 CTYVLAKDCsEEPDFSFSVTNKNCNGGASGVCLKSVTVIVG 63
VWD smart00216
von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D ...
 2-41 2.46e-06

von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D domains: D1 and D2 are present within the N-terminal propeptide whereas the remaining D domains are required for multimerisation.


Pssm-ID: 214566 [Multi-domain]  Cd Length: 163  Bit Score: 40.85  E-value: 2.46e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 125491754     2 CQYLLARDCEDH-SFSIVIETVQCadDPDAVCTRSVTVRLP 41
Cdd:smart00216  34 CYYVLAQDCSSEpTFSVLLKNVPC--GGGATCLKSVKVELN 72
 
Name Accession Description Interval E-value
VWD pfam00094
von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is ...
 2-41 1.14e-07

von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.


Pssm-ID: 459671 [Multi-domain]  Cd Length: 154  Bit Score: 44.28  E-value: 1.14e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 125491754    2 CQYLLARDC-EDHSFSIVIETVQCADDPDAVCTRSVTVRLP 41
Cdd:pfam00094  23 CTYVLAKDCsEEPDFSFSVTNKNCNGGASGVCLKSVTVIVG 63
VWD smart00216
von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D ...
 2-41 2.46e-06

von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D domains: D1 and D2 are present within the N-terminal propeptide whereas the remaining D domains are required for multimerisation.


Pssm-ID: 214566 [Multi-domain]  Cd Length: 163  Bit Score: 40.85  E-value: 2.46e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 125491754     2 CQYLLARDCEDH-SFSIVIETVQCadDPDAVCTRSVTVRLP 41
Cdd:smart00216  34 CYYVLAQDCSSEpTFSVLLKNVPC--GGGATCLKSVKVELN 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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