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Conserved domains on  [gi|156079716|gb|ABU48445|]
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putative replication-associated protein [Swan circovirus]

Protein Classification

replication-associated family protein( domain architecture ID 10261052)

replication-associated family protein similar to replication-associated protein and Para-Rep C1/7/9, both of which are ATP-dependent helicases

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 164-248 3.09e-19

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


:

Pssm-ID: 459992  Cd Length: 102  Bit Score: 80.73  E-value: 3.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156079716  164 IVLIGPPGSGKSRYA----------FEFPAERKYYK-ARGKWWDGYEGNDVVVMDDFYGW---LPYDDLLRICDRYP--- 226
Cdd:pfam00910   1 IWLYGPPGCGKSTLAkylarallkkLGLPKDSVYSRnPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPypp 80

                          90       100
                  ....*....|....*....|....
gi 156079716  227 --IRVEYKGgmTQFVAKTLIITSN 248
Cdd:pfam00910  81 pmAALEEKG--TPFTSKFVIVTSN 102
Viral_Rep super family cl03577
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 11-96 5.19e-14

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


The actual alignment was detected with superfamily member pfam02407:

Pssm-ID: 280553  Cd Length: 82  Bit Score: 66.05  E-value: 5.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156079716   11 RWVFTINNPTfedyvSVIEFCTAENCKFAIVGEEKGEkEGTPHLQGFLSLRKNARAAALEENLGGRAWLSRAVGSDEENE 90
Cdd:pfam02407   3 CWCFTLNNPT-----EFLSLFSQDELKYFVYQDERGT-TGTKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEEAR 76


                  ....*.
gi 156079716   91 EYCSKE 96
Cdd:pfam02407  77 DYCMKE 82
FlhF super family cl34260
Flagellar biosynthesis GTPase FlhF [Cell motility];
119-174 4.42e-03

Flagellar biosynthesis GTPase FlhF [Cell motility];


The actual alignment was detected with superfamily member COG1419:

Pssm-ID: 441029 [Multi-domain]  Cd Length: 361  Bit Score: 38.31  E-value: 4.42e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 156079716 119 SEVLAGALMTDVARKYPTTYIMfGRGLERLRQLIVETPRDWKTE--VIVLIGPPGSGK 174
Cdd:COG1419  121 SPELARELLEKLPEDLSAEEAW-RALLEALARRLPVAEDPLLDEggVIALVGPTGVGK 177
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 164-248 3.09e-19

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 80.73  E-value: 3.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156079716  164 IVLIGPPGSGKSRYA----------FEFPAERKYYK-ARGKWWDGYEGNDVVVMDDFYGW---LPYDDLLRICDRYP--- 226
Cdd:pfam00910   1 IWLYGPPGCGKSTLAkylarallkkLGLPKDSVYSRnPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPypp 80

                          90       100
                  ....*....|....*....|....
gi 156079716  227 --IRVEYKGgmTQFVAKTLIITSN 248
Cdd:pfam00910  81 pmAALEEKG--TPFTSKFVIVTSN 102
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 11-96 5.19e-14

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 66.05  E-value: 5.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156079716   11 RWVFTINNPTfedyvSVIEFCTAENCKFAIVGEEKGEkEGTPHLQGFLSLRKNARAAALEENLGGRAWLSRAVGSDEENE 90
Cdd:pfam02407   3 CWCFTLNNPT-----EFLSLFSQDELKYFVYQDERGT-TGTKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEEAR 76


                  ....*.
gi 156079716   91 EYCSKE 96
Cdd:pfam02407  77 DYCMKE 82
COG4639 COG4639
Predicted kinase [General function prediction only];
160-178 5.97e-04

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 39.43  E-value: 5.97e-04
                         10
                 ....*....|....*....
gi 156079716 160 KTEVIVLIGPPGSGKSRYA 178
Cdd:COG4639    1 MLSLVVLIGLPGSGKSTFA 19
FlhF COG1419
Flagellar biosynthesis GTPase FlhF [Cell motility];
119-174 4.42e-03

Flagellar biosynthesis GTPase FlhF [Cell motility];


Pssm-ID: 441029 [Multi-domain]  Cd Length: 361  Bit Score: 38.31  E-value: 4.42e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 156079716 119 SEVLAGALMTDVARKYPTTYIMfGRGLERLRQLIVETPRDWKTE--VIVLIGPPGSGK 174
Cdd:COG1419  121 SPELARELLEKLPEDLSAEEAW-RALLEALARRLPVAEDPLLDEggVIALVGPTGVGK 177
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 164-248 3.09e-19

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 80.73  E-value: 3.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156079716  164 IVLIGPPGSGKSRYA----------FEFPAERKYYK-ARGKWWDGYEGNDVVVMDDFYGW---LPYDDLLRICDRYP--- 226
Cdd:pfam00910   1 IWLYGPPGCGKSTLAkylarallkkLGLPKDSVYSRnPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPypp 80

                          90       100
                  ....*....|....*....|....
gi 156079716  227 --IRVEYKGgmTQFVAKTLIITSN 248
Cdd:pfam00910  81 pmAALEEKG--TPFTSKFVIVTSN 102
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 11-96 5.19e-14

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 66.05  E-value: 5.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156079716   11 RWVFTINNPTfedyvSVIEFCTAENCKFAIVGEEKGEkEGTPHLQGFLSLRKNARAAALEENLGGRAWLSRAVGSDEENE 90
Cdd:pfam02407   3 CWCFTLNNPT-----EFLSLFSQDELKYFVYQDERGT-TGTKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEEAR 76


                  ....*.
gi 156079716   91 EYCSKE 96
Cdd:pfam02407  77 DYCMKE 82
COG4639 COG4639
Predicted kinase [General function prediction only];
160-178 5.97e-04

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 39.43  E-value: 5.97e-04
                         10
                 ....*....|....*....
gi 156079716 160 KTEVIVLIGPPGSGKSRYA 178
Cdd:COG4639    1 MLSLVVLIGLPGSGKSTFA 19
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 141-227 1.56e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 38.64  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156079716  141 FGRG--LERLRQLIvETPRDWKTEVIVLIGPPGSGKS---RYAFEFPAERKYYKARGKWwdgyegndvvvmDDFygwLPY 215
Cdd:pfam13191   3 VGREeeLEQLLDAL-DRVRSGRPPSVLLTGEAGTGKTtllRELLRALERDGGYFLRGKC------------DEN---LPY 66

                          90
                  ....*....|..
gi 156079716  216 DDLLRICDRYPI 227
Cdd:pfam13191  67 SPLLEALTREGL 78
FlhF COG1419
Flagellar biosynthesis GTPase FlhF [Cell motility];
119-174 4.42e-03

Flagellar biosynthesis GTPase FlhF [Cell motility];


Pssm-ID: 441029 [Multi-domain]  Cd Length: 361  Bit Score: 38.31  E-value: 4.42e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 156079716 119 SEVLAGALMTDVARKYPTTYIMfGRGLERLRQLIVETPRDWKTE--VIVLIGPPGSGK 174
Cdd:COG1419  121 SPELARELLEKLPEDLSAEEAW-RALLEALARRLPVAEDPLLDEggVIALVGPTGVGK 177
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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