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Conserved domains on  [gi|169787751|gb|ACA80277|]
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NADH dehydrogenase subunt 2 (mitochondrion) [Probosciger aterrimus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.99e-149

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 424.62  E-value: 1.99e-149
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWS 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  81 SGQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPTLLSTMAIT 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 241 NSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSNKMKQWSAKKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 169787751 321 INILIPPFTLLSLSLLPLSPMILTTT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.99e-149

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 424.62  E-value: 1.99e-149
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWS 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  81 SGQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPTLLSTMAIT 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 241 NSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSNKMKQWSAKKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 169787751 321 INILIPPFTLLSLSLLPLSPMILTTT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-296 2.13e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 2.13e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   7 FILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLIS-KSHHPRAIEATIKYFLTQATASMLILF-SSMTNAwSSGQW 84
Cdd:COG1007  105 YALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSL 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  85 DITQLTNPLS------------CLLLTTAVAIKLGLTPFHFWFPEVLQGSslstalllstamklpPTTI----------- 141
Cdd:COG1007  184 NLAGIAAALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGA---------------PTPVtaflatapkia 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 142 --------LLLTSHSLNP---TLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTI-IITYNPK-LTLLTFYL- 207
Cdd:COG1007  249 afaallrlLVEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYLl 328

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 208 -YTLMTTSIFLTMNS-ANTLKLSTLMTSW----TKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATI 281
Cdd:COG1007  329 aYLFMNLGAFAVILLlSRKGGEAEEIEDLaglaRRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVI 408

                        330
                 ....*....|....*
gi 169787751 282 ISMLSLLGLFFYLRL 296
Cdd:COG1007  409 AVLNSVISAYYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 2.41e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 92.38  E-value: 2.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   23 SNHWVMAWAGLEINTLTILPLI-SKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWSSGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   91 NPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAM-KLPPTTILLLTS--HSLNPT---LLSTMAITSIAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  165 GGWMGLNQTQTRKILAFSSISHLGWMTIII----TYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLST---LMTS--WT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTrniRDYGglAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 169787751  236 KTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 7-296 6.44e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 87.31  E-value: 6.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751    7 FILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLIS-KSHHPRAIEATIKYFLTQATASMLILFSSMTNAWSSGQWD 85
Cdd:TIGR01770 105 YILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   86 ITQLTNPLSC------------LLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILL-------LTS 146
Cdd:TIGR01770 185 FEDLLLFLSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGF 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  147 HSLNPTLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTL--LTFYL--YTLMTTSIF---LTM 219
Cdd:TIGR01770 265 SEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYIfiYALMSLGAFgvlSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  220 NSAN---TLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRL 296
Cdd:TIGR01770 345 RSYKdewIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.99e-149

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 424.62  E-value: 1.99e-149
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWS 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  81 SGQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPTLLSTMAIT 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 241 NSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSNKMKQWSAKKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 169787751 321 INILIPPFTLLSLSLLPLSPMILTTT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-329 5.84e-122

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 354.61  E-value: 5.84e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWS 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  81 SGQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPTLLSTMAIT 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 241 NSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSNKMKQWSAKKP 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320


                 ....*....
gi 169787751 321 INILIPPFT 329
Cdd:MTH00070 321 TNNLLSLTI 329
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-315 1.08e-121

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 354.11  E-value: 1.08e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWS 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  81 SGQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTtILLLTSHSLNPTLLSTMAIT 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAPTNPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 169787751 241 NSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSNKMKQW 315
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPW 314
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-346 4.46e-110

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 324.49  E-value: 4.46e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWS 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  81 SGQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPTLLSTMAIT 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 241 NSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSN-KMKQWSAKK 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNmKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 169787751 320 PINILIPPFTLLSLSLLPLSPMILTTT 346
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 5.10e-91

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 276.08  E-value: 5.10e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWS 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  81 SGQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPTLLSTMAIT 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 241 NSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSNKMKQWSAKKP 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*.
gi 169787751 321 INILIPPFTLLSLSLLPLSPMILTTT 346
Cdd:MTH00200 321 SNLLVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-326 4.91e-81

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 250.62  E-value: 4.91e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWS 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  81 SGQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPTLLSTMAIT 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVL 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 241 NSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSNKMKQWSAKKP 320
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320


                 ....*.
gi 169787751 321 INILIP 326
Cdd:MTH00041 321 ITVYGV 326
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-325 9.27e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 182.33  E-value: 9.27e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWS 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  81 SGqwditqLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPttiLLLTSHSLNPTLLSTMAIT 160
Cdd:MTH00160  82 LM------LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAP---LILLSYLINNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVL 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 241 NSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSNKMKQWSAKKP 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFS 312


                 ....*
gi 169787751 321 INILI 325
Cdd:MTH00160 313 LILNF 317
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 16-325 2.48e-45

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 157.36  E-value: 2.48e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  16 GTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWSSGQWDITqltnplsc 95
Cdd:MTH00144  16 GTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM-------- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  96 LLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPttILLLTSHSLNPTLLST---MAITSIALGGWMGLNQ 172
Cdd:MTH00144  88 SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAP--LFLLSNFLDLYWLAYLlcvISVLSALVGSIGGLNQ 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 173 TQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTlMTSWTKTPVLNSTLMLTLLSLA 252
Cdd:MTH00144 166 TQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKD-LGSLKPSYKTGLSIISLLLSLG 244

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 169787751 253 GLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITlppnpSNKMKQWSAKKPINILI 325
Cdd:MTH00144 245 GLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLS-----SSKSKKSNSSKVLNSSI 312
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 5-310 1.53e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 150.32  E-value: 1.53e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   5 TKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSmtnawsSGQW 84
Cdd:MTH00011   7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  85 DITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPTLLSTMAITSIAL 164
Cdd:MTH00011  81 SFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 165 GGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVLNSTL 244
Cdd:MTH00011 161 GGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 169787751 245 MLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYcSTITLPPNPSN 310
Cdd:MTH00011 241 FIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS 305
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 7-313 1.59e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 134.03  E-value: 1.59e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   7 FILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWSSgqwdi 86
Cdd:MTH00197   1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL----- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  87 tqLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPttILLLTSHSLNPTLLSTMAITSIALGG 166
Cdd:MTH00197  76 --YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 167 WMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLSTLMTSWTKTPVLNSTLML 246
Cdd:MTH00197 152 IGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGL 231

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 169787751 247 TLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTYCSTITLPPNPSNKMK 313
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMK 298
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-296 2.13e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 2.13e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   7 FILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLIS-KSHHPRAIEATIKYFLTQATASMLILF-SSMTNAwSSGQW 84
Cdd:COG1007  105 YALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSL 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  85 DITQLTNPLS------------CLLLTTAVAIKLGLTPFHFWFPEVLQGSslstalllstamklpPTTI----------- 141
Cdd:COG1007  184 NLAGIAAALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGA---------------PTPVtaflatapkia 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 142 --------LLLTSHSLNP---TLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTI-IITYNPK-LTLLTFYL- 207
Cdd:COG1007  249 afaallrlLVEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYLl 328

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 208 -YTLMTTSIFLTMNS-ANTLKLSTLMTSW----TKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATI 281
Cdd:COG1007  329 aYLFMNLGAFAVILLlSRKGGEAEEIEDLaglaRRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVI 408

                        330
                 ....*....|....*
gi 169787751 282 ISMLSLLGLFFYLRL 296
Cdd:COG1007  409 AVLNSVISAYYYLRV 423
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-296 9.19e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 97.41  E-value: 9.19e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  16 GTMITITSNHWVMAWAGLEINTLTILPLI-SKSHHPRAIEATIKYFLTQATASMLILFS-------------SMTNAWSS 81
Cdd:MTH00196   5 GILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINLVLN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  82 GQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLltSHSLNPTLLSTMAITS 161
Cdd:MTH00196  85 SGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILV--SIGLNVNILLIGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 162 IALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNP----KLTLLTFYLYTLMTTSIFLTMNSANTLK--LSTLMTSWT 235
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSGLSR 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 169787751 236 KTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRL 296
Cdd:MTH00196 243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 2.41e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 92.38  E-value: 2.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   23 SNHWVMAWAGLEINTLTILPLI-SKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWSSGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   91 NPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAM-KLPPTTILLLTS--HSLNPT---LLSTMAITSIAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  165 GGWMGLNQTQTRKILAFSSISHLGWMTIII----TYNPKLTLLTFYLYTLMTTSIFLTMNSANTLKLST---LMTS--WT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTrniRDYGglAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 169787751  236 KTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
7-296 1.25e-20

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 92.58  E-value: 1.25e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   7 FILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLIS-KSHHPRAIEATIKYFLTQATASMLILFSSMTNAWSSGQWD 85
Cdd:PRK05777 106 YLLVLFALLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  86 ITQLTNPLS------------CLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKL----PPTTILLLTSHSL 149
Cdd:PRK05777 186 FAGIAKALAdgsgnsllllfgLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGL 265

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 150 NPT---LLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTI---IITYNPKLTLLtFYL--YTLMTTSIF--LTM 219
Cdd:PRK05777 266 SEDwqqVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVglaAGTAEGYSAVL-FYLlaYLFMTLGAFgvISL 344

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 220 NSANTLKLSTLmTSWT----KTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLR 295
Cdd:PRK05777 345 LRRKGGEAESI-SDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423


                 .
gi 169787751 296 L 296
Cdd:PRK05777 424 V 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 7-296 6.44e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 87.31  E-value: 6.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751    7 FILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLIS-KSHHPRAIEATIKYFLTQATASMLILFSSMTNAWSSGQWD 85
Cdd:TIGR01770 105 YILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   86 ITQLTNPLSC------------LLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILL-------LTS 146
Cdd:TIGR01770 185 FEDLLLFLSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGF 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  147 HSLNPTLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTL--LTFYL--YTLMTTSIF---LTM 219
Cdd:TIGR01770 265 SEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYIfiYALMSLGAFgvlSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  220 NSAN---TLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRL 296
Cdd:TIGR01770 345 RSYKdewIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-296 1.90e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 85.84  E-value: 1.90e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   8 ILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLIS-KSHHPRAIEATIKYFLTQATASMLILFSSMTNAWSSGQWDI 86
Cdd:MTH00199 101 ILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSI 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  87 ----TQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPTLLStmAITSI 162
Cdd:MTH00199 181 qginSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSI 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 163 ALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNP----KLTLLTFYLYTLMTT---SIFLTMNSANTLKLSTLMTSwT 235
Cdd:MTH00199 259 IYGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSIcsfSIILSLKLTKGLIVEVSGLS-R 337

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 169787751 236 KTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRL 296
Cdd:MTH00199 338 KNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 7-296 1.69e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 79.81  E-value: 1.69e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   7 FILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATASMLILFSSMTNAWSSGQWDI 86
Cdd:COG0651  110 YPLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNM 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  87 TQLTNPLS----------CLLLTTAVAIKLGLTPFHFWFPEVlqgsslstalllstaMKLPPT----------------- 139
Cdd:COG0651  190 ADLAARLAeldpglllaaFALLLVGFGIKAALFPLHFWLPDA---------------YPAAPSpvsallsglltkvgvya 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 140 ---TILLLTSHSLNP---TLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLY----T 209
Cdd:COG0651  255 ilrVLTLLFGADPALflgTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhA 334

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 210 LMTTSIFLT----MNSANTLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISML 285
Cdd:COG0651  335 LAKALLFLAagaiERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLS 414

                        330
                 ....*....|.
gi 169787751 286 SLLGLFFYLRL 296
Cdd:COG0651  415 SLLTLAYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 3-296 2.58e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 76.82  E-value: 2.58e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   3 PLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAI---------EATIKYFLTQATASMLILF- 72
Cdd:MTH00198 187 PRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFg 266

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  73 ----------SSMTNAWSSGQWDITQL---TNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLppT 139
Cdd:MTH00198 267 calyfgftgnEGMLGTILSATLETTNIelrQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--T 344

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 140 TILLLTSHSLNPTLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIII---TYNPKLTLLTFYLYTLMTTSIF 216
Cdd:MTH00198 345 VYILLTSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVsagTYESLQASWTYAVTYLVSALAS 424

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 217 LTM----------------------NSANTLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQE 274
Cdd:MTH00198 425 FTVictleefgtrtptsrqrdgsfgNYNLVRRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIA 504

                        330       340
                 ....*....|....*....|....*....
gi 169787751 275 MTVTATIISMLSLLGL-------FFYLRL 296
Cdd:MTH00198 505 FSSSLSIYYLVALFAIictcisaFYYIRI 533
ndhB CHL00049
NADH dehydrogenase subunit 2
 1-263 8.85e-11

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 62.71  E-value: 8.85e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   1 MSPLTKFILALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHP-RAIEATIKYFLTQATASMLILFS-SMTNA 78
Cdd:CHL00049 108 MAITEFLLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVYGfSWLYG 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  79 WSSGQWDI---------TQLTNPLSCLL----LTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLP----PTTI 141
Cdd:CHL00049 188 LSGGEIELqeivnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAasalATRI 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 142 LLLTSHSLNP---TLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTI-IITYNPKLTLLTFYLYTLMttSIFL 217
Cdd:CHL00049 268 FDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIgIIVGDSNDGYASMITYMLF--YIFM 345

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 169787751 218 TMNSANTLKLSTLMT----------SWTKTPVLNSTLMLTLLSLAGLPPLTGFLPK 263
Cdd:CHL00049 346 NLGTFACIVLFGLRTgtdnirdyagLYTKDPFLALSLALCLLSLGGIPPLAGFFGK 401
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
2-263 8.26e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 53.52  E-value: 8.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   2 SPLTKFI-LALSLTSGTMITITSNHWVMAWAGLEinTLTILPLISKSH---HPRAIEATIKYFLTQATASMLILF-SSMT 76
Cdd:PRK02504 107 TPLGEFAaILLTATLGGMFLSGATELVMIFISLE--TLSIASYLLTGYmkrDPRSNEAALKYLLIGAASSAIFLYgSSLL 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  77 NAWSSGQWDITQLTNPL----------SCLLLTTAVAIKLGLTPFHFWFPEVLQGSSLSTALLLSTAMKLPPTTI---LL 143
Cdd:PRK02504 185 YGLSGGSTQLSAIALALitspslglalALVFVIAGIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALairLL 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 144 LTSHSLNPT----LLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTI--IITYNPKLTLLTFYL--YTLMT--- 212
Cdd:PRK02504 265 VTAFPSFDEqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIglVAGTEAGYASMVFYLlaYLFMNlga 344

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 169787751 213 -TSIFLTMNSANTLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPK 263
Cdd:PRK02504 345 fACVILFSLRTGTDQISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-192 9.91e-08

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 53.16  E-value: 9.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  49 HPRAIEATIKYFLTQATASMLILFSSMTNAWSSGQW--DITQLTN-PLS-------CLLLTTAVAIKLGLTPFHFWFPEV 118
Cdd:COG1008  156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAaPLPltaqlllFLAFFIAFAVKVPMFPFHTWLPDA 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 119 LQGSSlstalllstamklPPTTILL---------------------LTSHSLNPtLLSTMAITSIALGGWMGLNQTQTRK 177
Cdd:COG1008  236 HVEAP-------------TAGSVLLagvllkmggygllrfalplfpEASAYFAP-LLAALGVIGIIYGALVALAQTDLKR 301

                        170
                 ....*....|....*
gi 169787751 178 ILAFSSISHLGWMTI 192
Cdd:COG1008  302 LIAYSSVSHMGFVLL 316
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-287 4.69e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 51.25  E-value: 4.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  33 LEINTLTILPLIS-KSHHPRAIEATIKYFLTQATASMLILFS---------SMTNAWSSGQWDIT-QLTNPLSCLLLTTA 101
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGiallygqygTLNMAYLAVKMSENpTVVAKIALALFIAG 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 102 VAIKLGLTPFHFW----FPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSLNPT----LLSTMAITSIALGGWMGLNQT 173
Cdd:PRK08376 230 LAMKSGAVPVHMWlpdaYPAAPSSISAMLLVIKQAGLYALARVLFSIYGPAINLAtvgwVIIILGCLTMFVGVAMAVVQK 309

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 174 QTRKILAFSSISHLGWMTI-----IITYNPklTLLTFYLYTLMTTSIFLTMNSA--------------------NTLKLS 228
Cdd:PRK08376 310 DVKRLLAYHSVSQIGYMLLglgvgLAALGD--PAMASYGEIALAGGIYHIVNHAlykallfltagaviyetgtrNLNELG 387

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 169787751 229 TLMTSWTKTPVlnsTLMLTLLSLAGLPPLTGFLPKWLIIQE--LTKQEMTVTATIISMLSL 287
Cdd:PRK08376 388 GLARTMPKTTI---AFLIGAAAIVGLPPFNGFASKWLIYESsaLFNPILGVIAMIGSVLTL 445
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 9-298 2.36e-06

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 49.22  E-value: 2.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   9 LALSLTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHpRAIEATIKYFLTQATASMLILFSSMTNAWSSGQWDITQ 88
Cdd:PRK08668 103 FALMSLAGVLGVFLANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFAD 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  89 LTNPLS-----------CLLLTTAVAIKLGLTPFHFWFPE-----------VLQGSSLST-ALLLSTAMKLPPTTILLLT 145
Cdd:PRK08668 182 ISQGLIndtstgfalivFLFLLAFGVAKAGIFPLHVWAPDayseapqsfsaVLSGQLSKLgAYGFLLVLYVLPGTKLFSE 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 146 -----SHSLNPTLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLT----LLTFYLYTLMTTSIF 216
Cdd:PRK08668 262 fgtyrGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGfaggLFHVFNHALFKGLFF 341

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 217 LTMNS----ANTLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFF 292
Cdd:PRK08668 342 LIFAAviyrTGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLY 421


                 ....*.
gi 169787751 293 YLRLTY 298
Cdd:PRK08668 422 VFRPLA 427
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 3-270 5.91e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 47.84  E-value: 5.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   3 PLTKFILALSLTSGTMITI-TSNHWVMAWAGLEINTLTILPLISKSHH-PRAIEATIKYFLTQAT------ASMLILFS- 73
Cdd:COG1009  109 GLARFFAYLLLFMAAMLGLvLSDNLLLLFVFWELVGLCSYLLIGFWYEkPSARRAARKAFLVTRVgdlgllLGILLLGAi 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  74 ----SMTNAWSSGQWDITQLTNPLSCLLLTTAVAIKLGLTPFHFWFPEVLQGsslstalllstamklpPTTI-------- 141
Cdd:COG1009  189 agtlNFSELLAAAPTILSSPLLTLILLLLLLGAFGKSAQFPLHFWLPDAMEG----------------PTPVsallhaat 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 142 -------LLLTSH---SLNPTLLSTMAITSIA---LGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNpKLTLLTFYLY 208
Cdd:COG1009  253 mvkagvyLLARLSplfALSPVWLTVVAIIGAItalFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG-AYVAALFHLL 331

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 169787751 209 T---------LMTTSIFLTMNSANTLKLSTLmtsWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQEL 270
Cdd:COG1009  332 ThaffkallfLGAGSVIHATGTRDIRKMGGL---RKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAA 399
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-268 1.08e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 46.86  E-value: 1.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   50 PRAIEATIKYFLTQATASMLILFSSMTNAWSSGQ-WDITQLTN-PLSC-------LLLTTAVAIKLGLTPFHFWFPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELLNlPLPFgvqtwlfLAFFIAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  120 QGSSLSTALLLSTAMKLPPTTILLL-------TSHSLNPtLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTI 192
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTYGFLRFnlplfpdASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  193 IITYNPKLTLL--TFYLYT--LMTTSIFL----TMNSANTLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKW 264
Cdd:TIGR01972 311 GIFSFNELGISgaVFQMIShgLITAALFLlvgvLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEF 390


                  ....
gi 169787751  265 LIIQ 268
Cdd:TIGR01972 391 LILL 394
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 152-298 1.30e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 46.80  E-value: 1.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 152 TLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLL--TFYL--YTLMTTSIFLT----MNSAN 223
Cdd:PRK08375 272 WLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAagLLHLlhHALMKGALFLAagaiEVTYG 351

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 169787751 224 TLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTVTATIISMLSLLGLFFYLRLTY 298
Cdd:PRK08375 352 TRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK12650 PRK12650
DUF4040 family protein;
98-263 8.47e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 44.65  E-value: 8.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  98 LTTAVAIKLGLT--------PFHFWFPEVLQGSSLSTALLLSTAMKLPPTTILLLTSHSL--NPT---LLSTMAITSIAL 164
Cdd:PRK12650 206 LTTVVAVLIAVAaftksaqfPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFhdVAVwnwLLIIVGMITALM 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 165 GGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYT----LMTTSIFLTM----NSANTLKLSTLMTSWTK 236
Cdd:PRK12650 286 GAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTlahaLFKSSLFMLIgvvdHQAGTRDIRRLGSLWRR 365

                        170       180
                 ....*....|....*....|....*..
gi 169787751 237 TPVLNSTLMLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12650 366 MPFTFVSVTIAALSMAAVPPLFGFVSK 392
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 17-268 8.55e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 44.15  E-value: 8.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  17 TM-ITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFL------TQATASMLILFSSMTNAWSSGQWDI--T 87
Cdd:PRK06458 120 TMlLALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDGEMAIlwT 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  88 QLTNPLSCL---LLTTAVAI-------KLGLTPFHFWFPE-----------VLQGSSLSTALLLSTAMKLppttILLLTS 146
Cdd:PRK06458 200 ELLKHASLLdptLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYI----LIDAAI 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 147 HSLNP-TLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTLM----TTSIFLTMNS 221
Cdd:PRK06458 276 GSDFPgRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNhsltKSAIFFASGN 355

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 169787751 222 A----NTLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK06458 356 VlqkyGTRDINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILT 406
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 80-263 1.21e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 44.14  E-value: 1.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  80 SSGQWDITQL-TNPLSCLLLTTAVAI-------KLGLTPFHFWFPEVLQGSSLSTALLLSTAM---------KLPPTtil 142
Cdd:PRK12644 183 AAGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMvkagiylvaRLAPG--- 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 143 LLTSHSLNPTLLsTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIII---TYNPKLTLLTFYL-YTLMTTSIFLT 218
Cdd:PRK12644 260 FADVPVWRPTVL-VLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVgigTRDAALAGLAMLLaHALFKAALFLV 338

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 169787751 219 M----NSANTLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12644 339 VgiidHSTGTRDIRKLSGLGRRQPVLAVVAALAAASMAGLPPLLGFVAK 387
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 152-267 2.60e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 42.80  E-value: 2.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 152 TLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLY----TLMTTSIFLTMNSA----N 223
Cdd:PRK12662 280 NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFMVSGSIsyhfG 359

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 169787751 224 TLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLII 267
Cdd:PRK12662 360 TTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 4-210 4.10e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 42.05  E-value: 4.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751   4 LTKFILALS-LTSGTMITITSNHWVMAWAGLEINTLTILPLISKSHHPRAIEATIKYFLTQATA------SMLILFSSMT 76
Cdd:PRK08676 101 LKVFYLGFNlLLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTR 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  77 NAWSSGQWDITQLTNP----------LSCLLLTTAVAIKLGLTPFHFWFPEV-LQGSSLSTALLLSTAMKLPPTTILLLT 145
Cdd:PRK08676 181 QALGTGTLNWTELAAHasllspsvlgASFLFIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRLS 260

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 169787751 146 S-------HSLNPTLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLYTL 210
Cdd:PRK08676 261 AllrqsgaAEQFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
152-293 2.24e-03

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 39.55  E-value: 2.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 152 TLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTL--LTFYLYTLMT--TSIFLTMNSANTL-- 225
Cdd:PRK12663 273 PLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILLGLALGTPAGIngAIFYLVHDMVvkTALFLIAGSLVRLtg 352

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 169787751 226 --KLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLIIQ-ELTKQEMTVTAT-----IISMLSLLGLFFY 293
Cdd:PRK12663 353 yrSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQgALDNGAYILLALmlitsLITMYSLFRIFFL 428
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-194 2.30e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 39.63  E-value: 2.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  55 ATIKYFLTQATASMLILFSSMTNAWSSGQ--WDITQLTN---PLSCLLLT-----TAVAIKLGLTPFHFWFPE------- 117
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAksyPLALELLLyagflIAFGVKLPIFPLHTWLPDahgeasa 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 118 ----VLQGSSLSTALLLSTAMKLPpttiLLLTSHSLNPTLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTII 193
Cdd:PRK12561 218 pvsmILAGVLLKMGGYALIRFNVQ----MLPDAHVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLG 293


                 .
gi 169787751 194 I 194
Cdd:PRK12561 294 I 294
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 110-266 6.18e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 38.36  E-value: 6.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 110 PFHFWFPEVlqgsslstalllstaMKLP-PTTILLltsHS-------------LNPTLLSTM----------AITSIAlG 165
Cdd:PRK12647 213 PFHFWLPNA---------------MEAPtPVSAYL---HSatmvkagiyllarLNPVLGGTPlwqtilplfgGLTMLT-G 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 166 GWMGLNQTQTRKILAFSSISHLGWMTIIITYNPKLTLLTFYLY----TLMTTSIFLTM----NSANTLKLSTLMTSWTKT 237
Cdd:PRK12647 274 ALLAVRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFlvahSLYKGALFMVAgiidHETGTRDITKLGGLRRAM 353

                        170       180
                 ....*....|....*....|....*....
gi 169787751 238 PVLNSTLMLTLLSLAGLPPLTGFLPKWLI 266
Cdd:PRK12647 354 PITAAAALLAALSMAGLPPLFGFLAKELI 382
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-194 9.15e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 37.87  E-value: 9.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  50 PRAIEATIKYFLTQATASMLILFSSMT----NAWSSGQWDITQLTN-PLS---------CLLLttAVAIKLGLTPFHFWF 115
Cdd:PRK05846 157 KNRIYAATKFFLYTLLGSLLMLVAIIYlvvvYYNATGTFDIADLLNlPLPpgvqywlflAFFI--AFAVKMPMFPLHTWL 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 116 PE-----------VLQGSSLSTALLLSTAMKLPpttILLLTSHSLNPtLLSTMAITSIALGGWMGLNQTQTRKILAFSSI 184
Cdd:PRK05846 235 PDahvqaptagsvLLAGILLKMGAYGLLRFSLP---LFPDASHEFAP-IIITLGVIAIIYGALVALAQTDIKKLIAYSSI 310

                        170
                 ....*....|
gi 169787751 185 SHLGWMTIII 194
Cdd:PRK05846 311 SHMGFVTLGI 320
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
55-266 9.32e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 37.76  E-value: 9.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751  55 ATIKYFLTQATASMLILFSSMTNAWSSG--QWDITQL---TNPLSCLLLTTA-----VAIKLGLTPFHFWFPEV-LQGSS 123
Cdd:PRK06473 158 AATKFLLYTAISGILILVSFLGLVWLSGasSFDYEPLrshTLPLSTQLLLLApilvgFGIKIPLVPFHTWLPDAhVEAST 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 124 LSTALLLSTAMKLPPTTIL------LLTSHSLNPTLLSTMAITSIALGGWMGLNQTQTRKILAFSSISHLGWMTIIITYN 197
Cdd:PRK06473 238 PVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILLAAAAA 317

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787751 198 PKLTLLTFYL----YTLMTTSIFLTM-------NSANTLKLSTLMTSWTKTPVLNSTLMLTLLSLAGLPPLTGFLPKWLI 266
Cdd:PRK06473 318 TPLSILAAVFqmisHGLISALLFLLVgvvykktGSRDVDVLRGLLNPERGLPITGSLMILGVMASAGIPGMVGFIAEFLV 397
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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