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Conserved domains on  [gi|169787777|gb|ACA80290|]
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NADH dehydrogenase subunt 2 (mitochondrion) [Tanygnathus lucionensis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.59e-138

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 396.12  E-value: 2.59e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWS 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGQWDITQLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTALSTL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 161 SIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAATTISMLSLLSLFFYLRLAYCSTITLPPNPSNKMKLWSTKKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 169787777 321 TNILIPTLTSLSTSLLPLSPMILTTI 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.59e-138

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 396.12  E-value: 2.59e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWS 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGQWDITQLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTALSTL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 161 SIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAATTISMLSLLSLFFYLRLAYCSTITLPPNPSNKMKLWSTKKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 169787777 321 TNILIPTLTSLSTSLLPLSPMILTTI 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.37e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 101.24  E-value: 1.37e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   23 SNHWMMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDITQLTYPPSCN----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   97 ------LLTTAIAIKLGLAPFHFWFPEVLQGSSLT-TALLLSTMMKLPPISILLLSSHSLNPT-----LLTALSTLSIAL 164
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGYGLIRRSLLYLPSSpfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  165 GGWAGLNQTQTRKILAFSSISHMGWMTIII----IYNPKLTLLTFYIYALMTTSIFLA--------MNTTNTLKLPTLmt 232
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCagsviyrrVHTRNIRDYGGL-- 238

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 169787777  233 sWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWSIIQ 268
Cdd:pfam00361 239 -AKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-219 6.34e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 99.04  E-value: 6.34e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  14 LLGTTITISSNHWMMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASALVLF-SSMTNAwSTGQWDITQ--- 88
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGiaa 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  89 -LTYPPSCN--------LLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLST---------MMKLppISILLLSSHSLN 150
Cdd:COG1007  191 aLAAGGANSpllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATapkiaafaaLLRL--LVEAFPGLAADW 268

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 169787777 151 PTLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTL--LTFY--IYALMTTSIFLAM 219
Cdd:COG1007  269 QLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYllAYLFMNLGAFAVI 341
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-279 5.84e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.53  E-value: 5.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   14 LLGTTITISSNHWMMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDITQL--- 89
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLllf 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   90 --TYPPSCNLLT-------TAIAIKLGLAPFHFWFPEVLQGSSLTTALLLST---------MMKLPPISILLLSSHSLNp 151
Cdd:TIGR01770 192 lsNGMLNISLLLlgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIvpkiaifavFLRLFLYILFGFSEAWQI- 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  152 tLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTL--LTFY--IYALMTTSIFLAMNTTNTLKL 227
Cdd:TIGR01770 271 -FLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYifIYALMSLGAFGVLSLLRSYKD 349

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 169787777  228 P-----TLMTSWTKT-PTLNTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAA 279
Cdd:TIGR01770 350 EwieyiSDFAGLFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLA 407
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.59e-138

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 396.12  E-value: 2.59e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWS 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGQWDITQLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTALSTL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 161 SIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAATTISMLSLLSLFFYLRLAYCSTITLPPNPSNKMKLWSTKKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 169787777 321 TNILIPTLTSLSTSLLPLSPMILTTI 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-324 6.87e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 336.78  E-value: 6.87e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWS 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGQWDITQLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSlNPTLLTALSTL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 161 SIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAATTISMLSLLSLFFYLRLAYCSTITLPPNPSNKMKLWSTKKP 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319


                 ....
gi 169787777 321 TNIL 324
Cdd:MTH00135 320 QLTL 323
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-325 1.95e-114

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 335.74  E-value: 1.95e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWS 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGQWDITQLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTALSTL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 161 SIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAATTISMLSLLSLFFYLRLAYCSTITLPPNPSNKMKLWSTKKP 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320


                 ....*
gi 169787777 321 TNILI 325
Cdd:MTH00070 321 TNNLL 325
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-324 2.79e-99

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 297.14  E-value: 2.79e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWS 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGQWDITQLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTALSTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 161 SIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAATTISMLSLLSLFFYLRLAYCSTITLPPNPSN-KMK-LWSTK 318
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNmKMKwQFENT 320


                 ....*.
gi 169787777 319 KPTNIL 324
Cdd:MTH00105 321 KPMTLL 326
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-325 7.61e-88

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 267.99  E-value: 7.61e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWS 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGQWDITQLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTALSTL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 161 SIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAATTISMLSLLSLFFYLRLAYCSTITLPPNPSNKMKLWSTKKP 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320


                 ....*
gi 169787777 321 TNILI 325
Cdd:MTH00200 321 SNLLV 325
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 11-267 1.11e-76

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 239.45  E-value: 1.11e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  11 TSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDITQLT 90
Cdd:MTH00041  11 TSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  91 YPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTALSTLSIALGGWAGL 170
Cdd:MTH00041  91 NTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 171 NQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTLNTTLMLTLLS 250
Cdd:MTH00041 171 NQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILS 250

                        250
                 ....*....|....*..
gi 169787777 251 LAGLPPLTGFLPKWSII 267
Cdd:MTH00041 251 LGGLPPLTGFLNKFISL 267
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-325 1.15e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 168.85  E-value: 1.15e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWS 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGqwditqLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSShslNPTLLTALSTL 160
Cdd:MTH00160  82 LM------LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI---NNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 161 SIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTL 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAATTISMLSLLSLFFYLRLAYCSTITLppNPSNKMKLWSTKKP 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLN--YNKNKWNLKKKKNK 310


                 ....*
gi 169787777 321 TNILI 325
Cdd:MTH00160 311 FSLIL 315
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-275 4.10e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 151.58  E-value: 4.10e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTSLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWS 80
Cdd:MTH00144   1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGQWDITqltyppscNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNP-TLLTALST 159
Cdd:MTH00144  81 SFSWFSM--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISV 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 160 LSIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTlKLPTLMTSWTKTPT 239
Cdd:MTH00144 153 LSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDS-GSMKDLGSLKPSYK 231

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 169787777 240 LNTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEM 275
Cdd:MTH00144 232 TGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSP 267
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-275 3.27e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 149.54  E-value: 3.27e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   1 MSPTTKLMSTTsLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSmtnaws 80
Cdd:MTH00011   4 TFPTMFLFSST-MTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------ 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  81 TGQWDITQLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTALSTL 160
Cdd:MTH00011  77 TMMWSFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAM 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 161 SIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTL 240
Cdd:MTH00011 157 SALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTT 236

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEM 275
Cdd:MTH00011 237 SMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSM 271
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-270 1.78e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 139.42  E-value: 1.78e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  12 SLLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTgqwditqLTY 91
Cdd:MTH00197   6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL-------YLS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  92 PPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHslNPTLLTALSTLSIALGGWAGLN 171
Cdd:MTH00197  79 LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGGIGGMN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 172 QTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALMTTSIFLAMNTTNTLKLPTLMTSWTKTPTLNTTLMLTLLSL 251
Cdd:MTH00197 157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                        250
                 ....*....|....*....
gi 169787777 252 AGLPPLTGFLPKWSIIQEL 270
Cdd:MTH00197 237 GGLPPLSGFFLKWLILTSL 255
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-267 1.36e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 102.80  E-value: 1.36e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  13 LLLGTTITISSNHWMMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDI----- 86
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLsyinl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  87 --------TQLTYPPSCNLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTALs 158
Cdd:MTH00196  82 vlnsgqsfSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGL- 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 159 tLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIII----IYNPKLTLLTFYIYALMTTSIFLAMNTTNTLK--LPTLMT 232
Cdd:MTH00196 161 -FSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSG 239

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 169787777 233 SWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWSII 267
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.37e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 101.24  E-value: 1.37e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   23 SNHWMMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDITQLTYPPSCN----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   97 ------LLTTAIAIKLGLAPFHFWFPEVLQGSSLT-TALLLSTMMKLPPISILLLSSHSLNPT-----LLTALSTLSIAL 164
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGYGLIRRSLLYLPSSpfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  165 GGWAGLNQTQTRKILAFSSISHMGWMTIII----IYNPKLTLLTFYIYALMTTSIFLA--------MNTTNTLKLPTLmt 232
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCagsviyrrVHTRNIRDYGGL-- 238

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 169787777  233 sWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWSIIQ 268
Cdd:pfam00361 239 -AKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-219 6.34e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 99.04  E-value: 6.34e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  14 LLGTTITISSNHWMMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASALVLF-SSMTNAwSTGQWDITQ--- 88
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGiaa 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  89 -LTYPPSCN--------LLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLST---------MMKLppISILLLSSHSLN 150
Cdd:COG1007  191 aLAAGGANSpllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATapkiaafaaLLRL--LVEAFPGLAADW 268

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 169787777 151 PTLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTL--LTFY--IYALMTTSIFLAM 219
Cdd:COG1007  269 QLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYllAYLFMNLGAFAVI 341
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-267 8.24e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 95.85  E-value: 8.24e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  13 LLLGTTITISSNHWMMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDITQLTY 91
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  92 PPSCN----LLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPTLLTAlsTLSIALGGW 167
Cdd:MTH00199 186 ILTGDvgkiLITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICA--VLSIIYGAI 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 168 AGLNQTQTRKILAFSSISHMGW----MTIIIIYNPKLTLLTFYIYALMTT---SIFLAMNTTNTLKLPTLMTSwTKTPTL 240
Cdd:MTH00199 264 GALNQTKIKRLLAYSGIGHMGFilfgVAIGSFESIQASLIYMIIYVIMSIcsfSIILSLKLTKGLIVEVSGLS-RKNPVI 342

                        250       260
                 ....*....|....*....|....*..
gi 169787777 241 NTTLMLTLLSLAGLPPLTGFLPKWSII 267
Cdd:MTH00199 343 ALTLALTFLSIAGIPPLAGFLSKWLIL 369
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-216 1.55e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 83.33  E-value: 1.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  14 LLGTTITISSNHWMMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDITQLTYP 92
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKA 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  93 PSCN------------LLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLST---------MMKLppISILLLSSHSLNP 151
Cdd:PRK05777 193 LADGsgnsllllfglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATapkiaafavLLRL--LVVAFGGLSEDWQ 270

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 169787777 152 TLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTL--LTFY--IYALMTTSIF 216
Cdd:PRK05777 271 QVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsaVLFYllAYLFMTLGAF 339
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-279 5.84e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.53  E-value: 5.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   14 LLGTTITISSNHWMMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDITQL--- 89
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLllf 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   90 --TYPPSCNLLT-------TAIAIKLGLAPFHFWFPEVLQGSSLTTALLLST---------MMKLPPISILLLSSHSLNp 151
Cdd:TIGR01770 192 lsNGMLNISLLLlgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIvpkiaifavFLRLFLYILFGFSEAWQI- 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  152 tLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTL--LTFY--IYALMTTSIFLAMNTTNTLKL 227
Cdd:TIGR01770 271 -FLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYifIYALMSLGAFGVLSLLRSYKD 349

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 169787777  228 P-----TLMTSWTKT-PTLNTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEMTTAA 279
Cdd:TIGR01770 350 EwieyiSDFAGLFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLA 407
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 13-268 3.08e-15

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 76.34  E-value: 3.08e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  13 LLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDITQL--- 89
Cdd:COG0651  116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLaar 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  90 --TYPPS-----CNLLTTAIAIKLGLAPFHFWFPEVL-QGSSLTTALLLSTMMK-------------LPPISILLLSshs 148
Cdd:COG0651  196 laELDPGlllaaFALLLVGFGIKAALFPLHFWLPDAYpAAPSPVSALLSGLLTKvgvyailrvltllFGADPALFLG--- 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 149 lnpTLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIII-IYNPK-LTLLTFYI--YALMTTSIFLA----MN 220
Cdd:COG0651  273 ---TLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLgLGTPLgLAGALFHLlnHALAKALLFLAagaiER 349

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 169787777 221 TTNTLKLPTLMTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWSIIQ 268
Cdd:COG0651  350 ATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQ 397
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-263 2.29e-11

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 64.64  E-value: 2.29e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  51 RAIEATTKYFLVQAAASALVLFS-SMTNAWSTGQWDI---------TQLTYPPSCNL----LTTAIAIKLGLAPFHFWFP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGfSWLYGLSGGEIELqeivnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 117 EVLQGSSLTTALLLSTMMKLPPISILLLSSHSLNPT-------LLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGW 189
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYFssnewhlLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 190 MTIIII-------YNPKLTLLTFYIYALMTT--SIFLAMNTTNTLKLPTLMTSWTKTPTLNTTLMLTLLSLAGLPPLTGF 260
Cdd:CHL00049 319 VIIGIIvgdsndgYASMITYMLFYIFMNLGTfaCIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGIPPLAGF 398


                 ...
gi 169787777 261 LPK 263
Cdd:CHL00049 399 FGK 401
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-267 3.00e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 64.49  E-value: 3.00e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  15 LGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAI---------EATTKYFLVQAAASALVLFSSMTNAWSTGQWD 85
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNEG 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  86 ITQLTYPPSCN--------------LLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTMMKLppISILLLSSHSLNP 151
Cdd:MTH00198 279 MLGTILSATLEttnielrqgslgylFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITS 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 152 TLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIYALM-TTSIFLAMNTTNTL----- 225
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTyLVSALASFTVICTLeefgt 436

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 169787777 226 -------------------KLPTLMTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWSII 267
Cdd:MTH00198 437 rtptsrqrdgsfgnynlvrRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 38-192 1.63e-10

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 62.02  E-value: 1.63e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  38 LAIIP---LISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQW-----DITQLTYPPSCN-----LLTTAIAI 104
Cdd:COG1008  142 LMLIPmyfLIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfdiaELAAAPLPLTAQlllflAFFIAFAV 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 105 KLGLAPFHFWFPEVL-QGSSLTTALLLSTMMK----------LP--PISILLLSshslnpTLLTALSTLSIALGGWAGLN 171
Cdd:COG1008  222 KVPMFPFHTWLPDAHvEAPTAGSVLLAGVLLKmggygllrfaLPlfPEASAYFA------PLLAALGVIGIIYGALVALA 295

                        170       180
                 ....*....|....*....|.
gi 169787777 172 QTQTRKILAFSSISHMGWMTI 192
Cdd:COG1008  296 QTDLKRLIAYSSVSHMGFVLL 316
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-192 1.45e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 55.83  E-value: 1.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  50 PRAIEATTKYFLVQAAASALVLF-SSMTNAWSTGQWDIT----QLTYPPSCNLLTT------AIAIKLGLAPFHFWFPEV 118
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSaialALITSPSLGLALAlvfviaGIAFKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 119 LQGSSLTTALLLSTMMKLPPISILLLSSHSLNP-------TLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMT 191
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPsfdeqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316


                 .
gi 169787777 192 I 192
Cdd:PRK02504 317 I 317
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-194 2.42e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 55.33  E-value: 2.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777   50 PRAIEATTKYFLVQAAASALVLFS----SMTNAWSTGQWDITQLTYPPSCNLLT-----TAIAIKLGLAPFHFWFPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAilglYFLGGGTFDLLELLNLPLPFGVQTWLflaffIAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  120 QGSSLTTALLLSTMMKLPP------ISILLLSSHSLNPTLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTII 193
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTygflrfNLPLFPDASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLG 311


                  .
gi 169787777  194 I 194
Cdd:TIGR01972 312 I 312
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-194 4.73e-08

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 54.38  E-value: 4.73e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  13 LLLGTTITISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAA------SALVLFSSMTNAWSTGQWDI 86
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  87 TQLT-----YPPSCNLLT-----TAIAIKLGLAPFHFWFPEV-LQGSSLTTALLLSTMMKLP-------PISILLLSSHS 148
Cdd:PRK08676 191 TELAahaslLSPSVLGASflfifIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGiygilrlSALLRQSGAAE 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 169787777 149 LNPTLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIII 194
Cdd:PRK08676 271 QFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGI 316
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-270 3.78e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.42  E-value: 3.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  33 LEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFS-SMTNAwSTGQWDITQLT--YPPSCNLLT------TAIA 103
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLAgaLAENPTVVTafgfvlLALA 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 104 IKLGLAPFHFWFPEVLQG-SSLTTALLLSTMMKLP---------PISILLLSSHSLNPTLLTALSTLSIALGGWAGLNQT 173
Cdd:PRK08375 214 LKAAVFPLHTWLPRAYPAaPPVVTALLSGLVTKVAvyaliriyfTVFGGDFRFALGLGWLLAVLALLSMLVGSLAALGQD 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 174 QTRKILAFSSISHMGWMTIIIIYNPKLTLL--TFYI--YALMTTSIFLA----MNTTNTLKLPTLMTSWTKTPTLNTTLM 245
Cdd:PRK08375 294 DVKRVLAYSTVSQMGYILLGLALLTPLALAagLLHLlhHALMKGALFLAagaiEVTYGTRRLSELSGLGRRMPLTAAAFA 373

                        250       260
                 ....*....|....*....|....*
gi 169787777 246 LTLLSLAGLPPLTGFLPKWSIIQEL 270
Cdd:PRK08375 374 VASLSLIGVPPTSGFVSKWYLVVGA 398
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 1.30e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 50.10  E-value: 1.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  33 LEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASALVLFSSmtnAWSTGQWDITQLTY--------PPSCN-----LL 98
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYlavkmsenPTVVAkialaLF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  99 TTAIAIKLGLAPFHFWFPEVLQG--SSLTTALLLST------MMKLPPISILLLSSHSLNPTLLTALSTLSIALGGWAGL 170
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWLPDAYPAapSSISAMLLVIKqaglyaLARVLFSIYGPAINLATVGWVIIILGCLTMFVGVAMAV 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 171 NQTQTRKILAFSSISHMGWM------TIIIIYNPKLTLL--------TFYI--YALMTTSIFLA----MNTTNTLKLPTL 230
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMllglgvGLAALGDPAMASYgeialaggIYHIvnHALYKALLFLTagavIYETGTRNLNEL 386

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 169787777 231 MTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWSI 266
Cdd:PRK08376 387 GGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 38-194 1.21e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 46.73  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  38 LAIIP---LISKSHHPRAIEATTKYFLVQAAASALVLFSSMT----NAWSTGQWDITQL-TYPPSCNLLT-------TAI 102
Cdd:PRK05846 142 AMLIPmyfLIGVWGGKNRIYAATKFFLYTLLGSLLMLVAIIYlvvvYYNATGTFDIADLlNLPLPPGVQYwlflaffIAF 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 103 AIKLGLAPFHFWFPEVLQ-----GSSLTTALLLST--------MMKLPPISILLLSshslnpTLLTALSTLSIALGGWAG 169
Cdd:PRK05846 222 AVKMPMFPLHTWLPDAHVqaptaGSVLLAGILLKMgaygllrfSLPLFPDASHEFA------PIIITLGVIAIIYGALVA 295

                        170       180
                 ....*....|....*....|....*
gi 169787777 170 LNQTQTRKILAFSSISHMGWMTIII 194
Cdd:PRK05846 296 LAQTDIKKLIAYSSISHMGFVTLGI 320
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-194 1.29e-05

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 46.95  E-value: 1.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  55 ATTKYFLVQAAASALVLFSSMTNAWSTGQ--WDITQLT---YPPSCNLLT-----TAIAIKLGLAPFHFWFPE------- 117
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGaksYPLALELLLyagflIAFGVKLPIFPLHTWLPDahgeasa 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 118 ----VLQGSSLTT---ALLLSTMMKLPPISILLLsshslnpTLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWM 190
Cdd:PRK12561 218 pvsmILAGVLLKMggyALIRFNVQMLPDAHVYFA-------PALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFV 290


                 ....
gi 169787777 191 TIII 194
Cdd:PRK12561 291 LLGI 294
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 20-192 6.17e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 44.54  E-value: 6.17e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  20 TISSNHWMMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASALVLFSS----MTNAWSTGQWDITQL-----T 90
Cdd:PRK06458 124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTilvyANAATVMGDGEMAILwtellK 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  91 YPPSCN--LLTTAIAI-------KLGLAPFHFWFPE-----------VLQGSSLTTALLLSTMMKLppiSILLLSSHSLN 150
Cdd:PRK06458 204 HASLLDptLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYI---LIDAAIGSDFP 280

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 169787777 151 PTLLTALSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTI 192
Cdd:PRK06458 281 GRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 80-263 7.46e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 44.53  E-value: 7.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  80 STGQWDITQL-TYPPSCNLLTTAIAI-------KLGLAPFHFWFPEVLQGSSLTTALLLSTMM---------KLPPISIL 142
Cdd:PRK12644 183 AAGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMvkagiylvaRLAPGFAD 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 143 LLSSHslnPTLLTaLSTLSIALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPK------LTLLTfyIYALMTTSIF 216
Cdd:PRK12644 263 VPVWR---PTVLV-LGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRdaalagLAMLL--AHALFKAALF 336

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 169787777 217 LAM----NTTNTLKLPTLMTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12644 337 LVVgiidHSTGTRDIRKLSGLGRRQPVLAVVAALAAASMAGLPPLLGFVAK 387
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
38-190 1.56e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 40.07  E-value: 1.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  38 LAIIPL---ISKSHHPRAIEATTKYFLVQAAASALVLFSSMTNAWSTG--QWDITQL---TYPPSCNLLTTA-----IAI 104
Cdd:PRK06473 138 LELIPLyllIAIWGGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGasSFDYEPLrshTLPLSTQLLLLApilvgFGI 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 105 KLGLAPFHFWFPEV-LQGSSLTTALLLSTMMKLPP-------ISILLLSSHSLNPTLLTaLSTLSIALGGWAGLNQTQTR 176
Cdd:PRK06473 218 KIPLVPFHTWLPDAhVEASTPVSVLLAGVLLKLGTygllrfgVGLFPEAWVYLAPWLAT-WAVVSVLYGASCAIAQKDMK 296

                        170
                 ....*....|....
gi 169787777 177 KILAFSSISHMGWM 190
Cdd:PRK06473 297 KMVAYSSIGHMGYI 310
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 34-275 3.46e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 39.21  E-value: 3.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  34 EINTLA---IIPLISKshhpRAIEATTKYFLVQAAASALVLFSSMTNAWSTGQWDITQ----LTYPPSCN-------LLT 99
Cdd:PRK08668 128 EIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADisqgLINDTSTGfalivflFLL 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 100 TAIAIKLGLAPFHFWFPE-----------VLQG--SSLTTALLLSTMMKLPPISILLLSSHSLNPTLLT----ALSTLSI 162
Cdd:PRK08668 204 AFGVAKAGIFPLHVWAPDayseapqsfsaVLSGqlSKLGAYGFLLVLYVLPGTKLFSEFGTYRGVPLFNyilaWLGNISI 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 163 ALGGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLL--TFYI--YALMTTSIFLAMNT----TNTLKLPTLMTSW 234
Cdd:PRK08668 284 IVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAggLFHVfnHALFKGLFFLIFAAviyrTGTTKISEMGGLI 363

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 169787777 235 TKTPTLNTTLMLTLLSLAGLPPLTGFLPKWSIIQELTKQEM 275
Cdd:PRK08668 364 EKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGM 404
PRK12650 PRK12650
DUF4040 family protein;
98-267 8.59e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.10  E-value: 8.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777  98 LTTAIAIKLGLA--------PFHFWFPEVLQGSSLTTALL-LSTMMKLPPISILLLSSHSLNPT----LLTALSTLSIAL 164
Cdd:PRK12650 206 LTTVVAVLIAVAaftksaqfPFHFWLPEAMAAITPVSAFLhAAAVVKAGIYLLLRFSPVFHDVAvwnwLLIIVGMITALM 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787777 165 GGWAGLNQTQTRKILAFSSISHMGWMTIIIIYNPKLTLLTFYIY----ALMTTSIFLAM----NTTNTLKLPTLMTSWTK 236
Cdd:PRK12650 286 GAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHtlahALFKSSLFMLIgvvdHQAGTRDIRRLGSLWRR 365

                        170       180       190
                 ....*....|....*....|....*....|.
gi 169787777 237 TPTLNTTLMLTLLSLAGLPPLTGFLPKWSII 267
Cdd:PRK12650 366 MPFTFVSVTIAALSMAAVPPLFGFVSKEGML 396
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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