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Conserved domains on  [gi|207582642|gb|ACI24886|]
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v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein, partial [Homo sapiens]

Protein Classification

immunoglobulin domain-containing protein( domain architecture ID 10621882)

immunoglobulin (Ig) domain-containing protein adopts a fold comprised of a sandwich of two beta sheets and may function in cell adhesion and pattern recognition

CATH:  2.60.40.10
PubMed:  10436082|9541533|7932691|8176743|23842991
SCOP:  3000071

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 1-30 6.40e-03

Immunoglobulin domain; This family contains immunoglobulin-like domains.


:

Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 30.23  E-value: 6.40e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 207582642   1 KPEILTYWH----VNGM---LQCVAAGFPEPTIDWYF 30
Cdd:pfam13927  1 KPVITVSPSsvtvREGEtvtLTCEATGSPPPTITWYK 37
 
Name Accession Description Interval E-value
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 1-30 6.40e-03

Immunoglobulin domain; This family contains immunoglobulin-like domains.


Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 30.23  E-value: 6.40e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 207582642   1 KPEILTYWH----VNGM---LQCVAAGFPEPTIDWYF 30
Cdd:pfam13927  1 KPVITVSPSsvtvREGEtvtLTCEATGSPPPTITWYK 37
Ig3_L1-CAM_like cd05731
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar ...
 14-29 6.41e-03

Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; The members here are composed of the third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM). L1 belongs to the L1 subfamily of cell adhesion molecules (CAMs) and is comprised of an extracellular region having six Ig-like domains and five fibronectin type III domains, a transmembrane region and an intracellular domain. L1 is primarily expressed in the nervous system and is involved in its development and function. L1 is associated with an X-linked recessive disorder, X-linked hydrocephalus, MASA syndrome, and spastic paraplegia type 1, that involves abnormalities of axonal growth. This group also contains the chicken neuron-glia cell adhesion molecule, Ng-CAM and human neurofascin.


Pssm-ID: 409394 [Multi-domain]  Cd Length: 83  Bit Score: 30.46  E-value: 6.41e-03
                        10
                ....*....|....*.
gi 207582642 14 LQCVAAGFPEPTIDWY 29
Cdd:cd05731  15 LECIAEGLPTPDIRWI 30
 
Name Accession Description Interval E-value
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 1-30 6.40e-03

Immunoglobulin domain; This family contains immunoglobulin-like domains.


Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 30.23  E-value: 6.40e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 207582642   1 KPEILTYWH----VNGM---LQCVAAGFPEPTIDWYF 30
Cdd:pfam13927  1 KPVITVSPSsvtvREGEtvtLTCEATGSPPPTITWYK 37
Ig3_L1-CAM_like cd05731
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar ...
 14-29 6.41e-03

Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; The members here are composed of the third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM). L1 belongs to the L1 subfamily of cell adhesion molecules (CAMs) and is comprised of an extracellular region having six Ig-like domains and five fibronectin type III domains, a transmembrane region and an intracellular domain. L1 is primarily expressed in the nervous system and is involved in its development and function. L1 is associated with an X-linked recessive disorder, X-linked hydrocephalus, MASA syndrome, and spastic paraplegia type 1, that involves abnormalities of axonal growth. This group also contains the chicken neuron-glia cell adhesion molecule, Ng-CAM and human neurofascin.


Pssm-ID: 409394 [Multi-domain]  Cd Length: 83  Bit Score: 30.46  E-value: 6.41e-03
                        10
                ....*....|....*.
gi 207582642 14 LQCVAAGFPEPTIDWY 29
Cdd:cd05731  15 LECIAEGLPTPDIRWI 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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