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Conserved domains on  [gi|291336539|gb|ADD96089|]
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proton translocating transhydrogenase subunit alpha 2 [uncultured organism MedDCM-OCT-S04-C478]

Protein Classification

NAD(P) transhydrogenase subunit alpha( domain architecture ID 10579553)

NAD(P) transhydrogenase subunit alpha is part of the enzyme complex that catalyzes the transhydrogenation between NADH and NADP which is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PNTB_4TM pfam12769
4TM region of pyridine nucleotide transhydrogenase, mitoch; PNTB_4TM is the region upstream of ...
 15-93 8.50e-32

4TM region of pyridine nucleotide transhydrogenase, mitoch; PNTB_4TM is the region upstream of family PNTB, pfam02233, that carries four of this transporters transmembrane regions. PNTB is the beta-subunit of pyridine nucleotide transhydrogenase. This family forms part of the Proton-translocating Transhydrogenase (PTH) Family.


:

Pssm-ID: 463694 [Multi-domain]  Cd Length: 84  Bit Score: 106.38  E-value: 8.50e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 291336539  15 ASFIGYELISKIPQTLHTPLMSGSNAISGITLIAAILIYPEiGESQLLKIIVLIAIAFATLNIVGGFSVTGRILEMFKK 93
Cdd:pfam12769  7 ALFVGYEVIWKVPPALHTPLMSVTNAISGIIIVGALLAAGG-GDTTLATVLGFIAVVLATINVVGGFLVTDRMLDMFKK 84
 
Name Accession Description Interval E-value
PNTB_4TM pfam12769
4TM region of pyridine nucleotide transhydrogenase, mitoch; PNTB_4TM is the region upstream of ...
 15-93 8.50e-32

4TM region of pyridine nucleotide transhydrogenase, mitoch; PNTB_4TM is the region upstream of family PNTB, pfam02233, that carries four of this transporters transmembrane regions. PNTB is the beta-subunit of pyridine nucleotide transhydrogenase. This family forms part of the Proton-translocating Transhydrogenase (PTH) Family.


Pssm-ID: 463694 [Multi-domain]  Cd Length: 84  Bit Score: 106.38  E-value: 8.50e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 291336539  15 ASFIGYELISKIPQTLHTPLMSGSNAISGITLIAAILIYPEiGESQLLKIIVLIAIAFATLNIVGGFSVTGRILEMFKK 93
Cdd:pfam12769  7 ALFVGYEVIWKVPPALHTPLMSVTNAISGIIIVGALLAAGG-GDTTLATVLGFIAVVLATINVVGGFLVTDRMLDMFKK 84
pntA PRK09424
Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha;
15-93 4.32e-22

Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha;


Pssm-ID: 236507 [Multi-domain]  Cd Length: 509  Bit Score: 88.35  E-value: 4.32e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291336539  15 ASFIGYELISKIPQTLHTPLMSGSNAISGITLIAAILiypEIG-ESQLLKIIVLIAIAFATLNIVGGFSVTGRILEMFKK 93
Cdd:PRK09424 433 ACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALL---QIGsGSGLVTFLAFIAVLIASINIFGGFTVTQRMLKMFRK 509
PntA COG3288
NAD/NADP transhydrogenase alpha subunit [Energy production and conversion];
15-51 2.96e-03

NAD/NADP transhydrogenase alpha subunit [Energy production and conversion];


Pssm-ID: 442518 [Multi-domain]  Cd Length: 359  Bit Score: 34.98  E-value: 2.96e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 291336539  15 ASFIGYELISKIPQTLHT--PLMSGSNAI---SGITLIAAIL 51
Cdd:COG3288  133 ANFAGYKAVLLAAPALHTffPLMSTAAGTirpAGVLVVGAGV 174
 
Name Accession Description Interval E-value
PNTB_4TM pfam12769
4TM region of pyridine nucleotide transhydrogenase, mitoch; PNTB_4TM is the region upstream of ...
 15-93 8.50e-32

4TM region of pyridine nucleotide transhydrogenase, mitoch; PNTB_4TM is the region upstream of family PNTB, pfam02233, that carries four of this transporters transmembrane regions. PNTB is the beta-subunit of pyridine nucleotide transhydrogenase. This family forms part of the Proton-translocating Transhydrogenase (PTH) Family.


Pssm-ID: 463694 [Multi-domain]  Cd Length: 84  Bit Score: 106.38  E-value: 8.50e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 291336539  15 ASFIGYELISKIPQTLHTPLMSGSNAISGITLIAAILIYPEiGESQLLKIIVLIAIAFATLNIVGGFSVTGRILEMFKK 93
Cdd:pfam12769  7 ALFVGYEVIWKVPPALHTPLMSVTNAISGIIIVGALLAAGG-GDTTLATVLGFIAVVLATINVVGGFLVTDRMLDMFKK 84
pntA PRK09424
Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha;
15-93 4.32e-22

Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha;


Pssm-ID: 236507 [Multi-domain]  Cd Length: 509  Bit Score: 88.35  E-value: 4.32e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291336539  15 ASFIGYELISKIPQTLHTPLMSGSNAISGITLIAAILiypEIG-ESQLLKIIVLIAIAFATLNIVGGFSVTGRILEMFKK 93
Cdd:PRK09424 433 ACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALL---QIGsGSGLVTFLAFIAVLIASINIFGGFTVTQRMLKMFRK 509
PntA COG3288
NAD/NADP transhydrogenase alpha subunit [Energy production and conversion];
15-51 2.96e-03

NAD/NADP transhydrogenase alpha subunit [Energy production and conversion];


Pssm-ID: 442518 [Multi-domain]  Cd Length: 359  Bit Score: 34.98  E-value: 2.96e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 291336539  15 ASFIGYELISKIPQTLHT--PLMSGSNAI---SGITLIAAIL 51
Cdd:COG3288  133 ANFAGYKAVLLAAPALHTffPLMSTAAGTirpAGVLVVGAGV 174
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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