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Conserved domains on  [gi|307550263|gb|ADN50328|]
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undecaprenyl diphosphate synthase [Vulcanisaeta distributa DSM 14429]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10000255)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates, similar to UPPS that catalyzes chain elongation of FPP by eight IPP to form the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis

Gene Ontology:  GO:0016765|GO:0000287|GO:0002094
PubMed:  22471620

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
2-238 5.98e-109

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


:

Pssm-ID: 439791  Cd Length: 248  Bit Score: 313.53  E-value: 5.98e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   2 QGALPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKleldllyrllKE- 80
Cdd:COG0020   12 PGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENW-KRPK----------EEv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  81 ----KLIK---VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDY 153
Cdd:COG0020   81 sflmGLLReylRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 154 NSGKLNISDLNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRE 233
Cdd:COG0020  161 AAGELDPEDIDEETISRYLYTAD--LPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRE 238


                 ....*
gi 307550263 234 RRFGK 238
Cdd:COG0020  239 RRFGG 243
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
2-238 5.98e-109

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 313.53  E-value: 5.98e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   2 QGALPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKleldllyrllKE- 80
Cdd:COG0020   12 PGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENW-KRPK----------EEv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  81 ----KLIK---VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDY 153
Cdd:COG0020   81 sflmGLLReylRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 154 NSGKLNISDLNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRE 233
Cdd:COG0020  161 AAGELDPEDIDEETISRYLYTAD--LPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRE 238


                 ....*
gi 307550263 234 RRFGK 238
Cdd:COG0020  239 RRFGG 243
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 8-231 9.28e-101

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 291.58  E-value: 9.28e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   8 HIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKleldllyrllKE-----KL 82
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENW-KRPK----------EEvdalmKL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  83 IK---VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLN 159
Cdd:cd00475   70 LReylEKELEELHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELD 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 307550263 160 ISDLNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSR 231
Cdd:cd00475  150 PEDITEELISKHLYTAD--LPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 12-237 4.42e-98

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 285.03  E-value: 4.42e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   12 IPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKleldllyrllKE-----KLIK-- 84
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENW-KRPK----------EEvdalmELLKee 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   85 --VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNsgKLNISD 162
Cdd:pfam01255  70 ylRRELPELHKNGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGK--KLDPED 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 307550263  163 LNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:pfam01255 148 IDEELISSHLYTAG--LPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 3-238 1.76e-71

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 218.59  E-value: 1.76e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   3 GALPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRskleldllyrllkekl 82
Cdd:PRK14830  20 GNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRP---------------- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  83 ikvrKDE-----------------RIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDA 145
Cdd:PRK14830  84 ----KDEvkflmnlpvefldkfvpELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 146 IKKILVDYNSGKLNISDLNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQA 225
Cdd:PRK14830 160 VKEIAKDVLDGKLNPEDITEELISNYLMTKG--LPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKA 237

                        250
                 ....*....|...
gi 307550263 226 LDDYSRRERRFGK 238
Cdd:PRK14830 238 IKDYQSRQRRFGG 250
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 8-237 7.02e-70

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 213.80  E-value: 7.02e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263    8 HIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKLELDLLYRLLKEKLikvrK 87
Cdd:TIGR00055   2 HVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENW-KRPKEEVDFLMELFEKKL----D 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   88 DER--IHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISDLNE 165
Cdd:TIGR00055  77 REVkeLHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDE 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 307550263  166 DTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:TIGR00055 157 ETLNKHLYTAN--LPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
2-238 5.98e-109

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 313.53  E-value: 5.98e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   2 QGALPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKleldllyrllKE- 80
Cdd:COG0020   12 PGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENW-KRPK----------EEv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  81 ----KLIK---VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDY 153
Cdd:COG0020   81 sflmGLLReylRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 154 NSGKLNISDLNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRE 233
Cdd:COG0020  161 AAGELDPEDIDEETISRYLYTAD--LPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRE 238


                 ....*
gi 307550263 234 RRFGK 238
Cdd:COG0020  239 RRFGG 243
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 8-231 9.28e-101

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 291.58  E-value: 9.28e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   8 HIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKleldllyrllKE-----KL 82
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENW-KRPK----------EEvdalmKL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  83 IK---VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLN 159
Cdd:cd00475   70 LReylEKELEELHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELD 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 307550263 160 ISDLNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSR 231
Cdd:cd00475  150 PEDITEELISKHLYTAD--LPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 12-237 4.42e-98

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 285.03  E-value: 4.42e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   12 IPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKleldllyrllKE-----KLIK-- 84
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENW-KRPK----------EEvdalmELLKee 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   85 --VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNsgKLNISD 162
Cdd:pfam01255  70 ylRRELPELHKNGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGK--KLDPED 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 307550263  163 LNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:pfam01255 148 IDEELISSHLYTAG--LPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 3-238 1.76e-71

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 218.59  E-value: 1.76e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   3 GALPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRskleldllyrllkekl 82
Cdd:PRK14830  20 GNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRP---------------- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  83 ikvrKDE-----------------RIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDA 145
Cdd:PRK14830  84 ----KDEvkflmnlpvefldkfvpELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 146 IKKILVDYNSGKLNISDLNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQA 225
Cdd:PRK14830 160 VKEIAKDVLDGKLNPEDITEELISNYLMTKG--LPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKA 237

                        250
                 ....*....|...
gi 307550263 226 LDDYSRRERRFGK 238
Cdd:PRK14830 238 IKDYQSRQRRFGG 250
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 8-237 7.02e-70

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 213.80  E-value: 7.02e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263    8 HIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKLELDLLYRLLKEKLikvrK 87
Cdd:TIGR00055   2 HVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENW-KRPKEEVDFLMELFEKKL----D 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   88 DER--IHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISDLNE 165
Cdd:TIGR00055  77 REVkeLHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDE 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 307550263  166 DTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:TIGR00055 157 ETLNKHLYTAN--LPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14835 PRK14835
isoprenyl transferase;
3-238 6.42e-67

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 207.77  E-value: 6.42e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   3 GALPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLELDLLYRLLKEKL 82
Cdd:PRK14835  39 GKLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNLFEREAR 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  83 iKVRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISD 162
Cdd:PRK14835 119 -RMAVDPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLLEAAATGKSPEE 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 163 LNE----DTLFRYLYIGDEPypEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFGK 238
Cdd:PRK14835 198 VAAeltpEHISAHLYTAGVP--DPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDYQGRERRFGR 275
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 1-238 1.73e-66

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 206.07  E-value: 1.73e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   1 MQGALPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLELDllyrllke 80
Cdd:PRK14836  10 ANENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSA-------- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  81 kLIKV------RKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYN 154
Cdd:PRK14836  82 -LMELflkaldREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 155 SGKLNISDLNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRER 234
Cdd:PRK14836 161 AGKLAPDEIDEALLAQHLALAD--LPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRER 238


                 ....
gi 307550263 235 RFGK 238
Cdd:PRK14836 239 RFGK 242
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 5-238 2.61e-64

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 200.36  E-value: 2.61e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   5 LPIHIGVIPDGNRRWARKVGLP-ITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLELDLLyrllkeKLI 83
Cdd:PRK14828  26 VPGHVGIIVDGNRRWARKAGFTdVSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLL------DII 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  84 KVRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISDL 163
Cdd:PRK14828 100 EDVVRQLAPDGRWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLTEHKDKGTSIDEL 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 307550263 164 NE----DTLFRYLYIGDEPypEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFGK 238
Cdd:PRK14828 180 AEsvtvDAISTHLYTGGQP--DPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALRDYSQRERRFGK 256
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 5-238 2.24e-63

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 197.86  E-value: 2.24e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   5 LPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLEldllyrllkEKLI- 83
Cdd:PRK14831  20 LPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEV---------NFLMt 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  84 ---KVRKDE--RIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKL 158
Cdd:PRK14831  91 lfeRVLRREleELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGEL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 159 NISDLNEDTLFRYLYIGDEPypEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFGK 238
Cdd:PRK14831 171 DPSEIDENLFESELYTAGIK--DPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFGG 248
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 5-237 3.38e-58

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 184.04  E-value: 3.38e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   5 LPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLELDLLYRLLKeklIK 84
Cdd:PRK14841   3 IPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQ---MI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  85 VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNIsdLN 164
Cdd:PRK14841  80 DREMELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVSQGKKIE--LT 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 307550263 165 EDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:PRK14841 158 EETFRQYLYLPD--VPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFG 228
PRK14834 PRK14834
isoprenyl transferase;
6-237 1.58e-55

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 178.02  E-value: 1.58e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   6 PIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLELDLLyrllkeKLIK- 84
Cdd:PRK14834  15 PRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLF------GLLRl 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  85 -VRKD-ERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISD 162
Cdd:PRK14834  89 fIRRDlAELHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEGRLDPAS 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 307550263 163 LNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:PRK14834 169 IDAETISANLDTAD--IPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRERRFG 241
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 5-238 3.72e-55

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 177.11  E-value: 3.72e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   5 LPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLELDLLYRLlkEKLIK 84
Cdd:PRK14832  18 IPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLF--ERLLR 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  85 vRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISDLN 164
Cdd:PRK14832  96 -RELAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAVN 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 307550263 165 EDTLFRYLYIGDEPypEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFGK 238
Cdd:PRK14832 175 EQLVEQHLYTADTP--PPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFGQ 246
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 5-238 8.56e-55

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 176.19  E-value: 8.56e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   5 LPIHIGVIPDGNRRWARK----VGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRrSKLELDLLYRLLKE 80
Cdd:PRK14840  18 LPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSR-SKEEVAELFSLFNS 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  81 KLikvrkDER---IHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGK 157
Cdd:PRK14840  97 QL-----DSQlpyLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLANKK 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 158 LNISDLNEDtLFRyLYIGDEPYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:PRK14840 172 ISSDDISEE-LIS-SYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQRSRRGG 249


                 .
gi 307550263 238 K 238
Cdd:PRK14840 250 K 250
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 2-237 9.37e-54

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 173.05  E-value: 9.37e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   2 QGALPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKLELDLLYRLLKEk 81
Cdd:PRK14829  11 KNKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENW-KRSPDEVRFLMGFSRD- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  82 lIKVRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNIS 161
Cdd:PRK14829  89 -VIHRRREQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKISGD 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 307550263 162 DLNEDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:PRK14829 168 RVTEKMISDHLYNPD--MPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFG 241
PRK14838 PRK14838
isoprenyl transferase;
5-238 1.67e-53

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 172.37  E-value: 1.67e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   5 LPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLELDLLYRllkekLIK 84
Cdd:PRK14838  10 IPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSL-----LLD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  85 VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISDLN 164
Cdd:PRK14838  85 SIEEETFMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNPEEIT 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 307550263 165 EDTLFRYLYIgdEPYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFGK 238
Cdd:PRK14838 165 EESISEHLTT--NFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFGK 236
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
5-237 5.52e-50

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 163.06  E-value: 5.52e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   5 LPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKLELDLLYRLLKEKLik 84
Cdd:PRK14833   4 TLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENW-KRPKSEVDFLMKLLKKYL-- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  85 vrKDER--IHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKiLVDYNSGKLNISD 162
Cdd:PRK14833  81 --KDERstYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKK-LLESPPSHIGELE 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 307550263 163 LNEDTLFRYLyigDEPY-PEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:PRK14833 158 SLEEEISNCL---DTADlPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 5-238 4.79e-46

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 155.11  E-value: 4.79e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   5 LPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKLELDLLYRLLKEklIK 84
Cdd:PRK14827  67 LPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENW-KRSPEEVRFLMGFNRD--VV 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  85 VRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISDLN 164
Cdd:PRK14827 144 RRRRDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGRLNPERIT 223

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 307550263 165 EDTLFRYLYIGDepYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFGK 238
Cdd:PRK14827 224 ESTIARHLQRPD--IPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGS 295
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
14-237 1.53e-44

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 148.98  E-value: 1.53e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  14 DGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLELDLLyrllkEKLIKVRKDE--RI 91
Cdd:PRK10240   2 DGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALM-----ELFVWALDSEvkSL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  92 HRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISDLNEDTLFRY 171
Cdd:PRK10240  77 HRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQH 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 307550263 172 LYIGDEPypEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:PRK10240 157 ICMHELA--PVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFG 220
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 2-238 2.50e-43

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 146.12  E-value: 2.50e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   2 QGALPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLEldllyrllkEK 81
Cdd:PRK14837   3 KNSLPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEI---------EH 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  82 LIKVRKD------ERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILvdynS 155
Cdd:PRK14837  74 LMFLIADylssefNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKKFL----S 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 156 GKLNISDLNEDTLFRYLyigDEP-YPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRER 234
Cdd:PRK14837 150 SGLDLETLNENVFSKFL---DNPeLPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKR 226


                 ....
gi 307550263 235 RFGK 238
Cdd:PRK14837 227 NFGR 230
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 5-237 6.21e-43

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 145.52  E-value: 6.21e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   5 LPIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKLELDLLYRLLKEkLIK 84
Cdd:PRK14842   8 IPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENW-KRPITEIRSIFGLLVE-FIE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  85 VRKDErIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKILVDYNSGKLNISD-L 163
Cdd:PRK14842  86 TRLDT-IHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEVFLARKAKKVTLEKpL 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 307550263 164 NEDTLFRYLYIgdEPYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRFG 237
Cdd:PRK14842 165 KEKEFEKFLYT--SPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTRKFG 236
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
1-237 8.74e-43

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 144.90  E-value: 8.74e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   1 MQGAL----PIHIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFlRRSKLELDLLYR 76
Cdd:PRK14839   1 MQSSLdrrsGLHVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNW-RRPAAEVGGLMR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  77 LLKEKLikVRKDERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEIIDAIKKilvdynsg 156
Cdd:PRK14839  80 LLRAYL--RNETERLARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAAAK-------- 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 157 KLNISDLNEDTLFRYLyigDEPYPEPDLIIRTGGEHRISNFLLYETAYSELYILNKYWPEITKEDLKQALDDYSRRERRF 236
Cdd:PRK14839 150 ALGPEGLSREAFSDLL---TGDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRF 226


                 .
gi 307550263 237 G 237
Cdd:PRK14839 227 G 227
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 8-215 1.77e-18

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 82.74  E-value: 1.77e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263   8 HIGVIPDGNRRWARKVGLPITEAYRIGSDKVEEFLDWSLDFGIKIVTVYVLSTENFLRRSKLELDLLYRLLkekLIKVRK 87
Cdd:PTZ00349  22 HISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLFYLNL---LILINE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263  88 D---ERIHRNRVRVRVIGRTWLLPEDVRREIALTEEATANYSDHYLNLAVVYGGRQEI----------IDAIKKILVDYN 154
Cdd:PTZ00349  99 DfffKFIKDNKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSRNEMslckfnpnlyFDTYKNLLEEKK 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307550263 155 -------------SGKLNISD------------LNEDTLFRYLYIGD-------------------------EPYPEPDL 184
Cdd:PTZ00349 179 ilcgsniltdpikEGTFAIPDdedecdyldhelENERIDLDLKFDGDcicgeksflneeqieivnyhkklltSDLPPPNI 258

                        250       260       270
                 ....*....|....*....|....*....|..
gi 307550263 185 IIRTGGEHRISNFLLYE-TAYSELYILNKYWP 215
Cdd:PTZ00349 259 LIRTSGEKRLSDFMLYQiSEFTEIYFINEYWP 290
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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