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Conserved domains on  [gi|350430915|gb|AEQ28425|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Hapalopsittaca amazonina]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.61e-137

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 394.19  E-value: 1.61e-137
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 TGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPTLLTTMSIM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 161 SITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 241 STTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITLPPNPSSKTKQWSTKSS 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 350430915 321 TNPLIPTLISLSISLLPLSPMILTIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.61e-137

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 394.19  E-value: 1.61e-137
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 TGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPTLLTTMSIM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 161 SITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 241 STTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITLPPNPSSKTKQWSTKSS 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 350430915 321 TNPLIPTLISLSISLLPLSPMILTIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 11-217 5.97e-22

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 96.34  E-value: 5.97e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  11 LSILLGTTLTITSNHWATAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQATASTLVLF--------SSTVN---- 77
Cdd:COG1007  109 LFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNlagi 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  78 AQHTGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKL--------PPTTLLLTTSHSL 149
Cdd:COG1007  189 AAALAAGGANSPLLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaallrLLVEAFPGLAADW 268

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 350430915 150 NPtLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKL----TLLAFFTYTLMTSSVFL 217
Cdd:COG1007  269 QL-LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFA 339
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.61e-17

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 81.59  E-value: 1.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   23 SNHWATAWAGLEINTLSIIPMI-SKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDITQL-TYPPACA---- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   97 ------LLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPT------LLTTMSIMSITL 164
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  165 GGWMGLNQTQTRKIMAFSSISHLGWMMVTI----TYNPKLTLLAFFTYTLMTSSVFL--------TMNTTNTLKLSTLmi 232
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsviyrRVHTRNIRDYGGL-- 238

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 350430915  233 aWTKAPMLSTTLMLTLLSLSGLPPLTGFLPKWLIMQ 268
Cdd:pfam00361 239 -AKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 11-297 6.17e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.53  E-value: 6.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   11 LSILLGTTLTITSNHWATAWAGLEINTLSI-IPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTV------------- 76
Cdd:TIGR01770 109 LFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLiygftgslnfedl 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   77 -NAQHTGQWDITQLTYppACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTS-------HS 148
Cdd:TIGR01770 189 lLFLSNGMLNISLLLL--GIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfgfSE 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  149 LNPTLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKL----TLLAFFTYTLMTS---SVFLTMNT 221
Cdd:TIGR01770 267 AWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLgafGVLSLLRS 346

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 350430915  222 TN---TLKLSTLMIAWTKAPMLSTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLA 297
Cdd:TIGR01770 347 YKdewIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.61e-137

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 394.19  E-value: 1.61e-137
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 TGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPTLLTTMSIM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 161 SITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 241 STTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITLPPNPSSKTKQWSTKSS 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 350430915 321 TNPLIPTLISLSISLLPLSPMILTIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-324 7.06e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 326.76  E-value: 7.06e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQH 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 TGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSlNPTLLTTMSIM 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 161 SITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPML 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 241 STTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITLPPNPSSKTKQWSTKSS 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319


                 ....
gi 350430915 321 TNPL 324
Cdd:MTH00135 320 QLTL 323
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-327 8.78e-110

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 323.80  E-value: 8.78e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQH 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 TGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPTLLTTMSIM 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 161 SITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPML 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 241 STTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITLPPNPSSKTKQWSTKSS 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320


                 ....*..
gi 350430915 321 TNPLIPT 327
Cdd:MTH00070 321 TNNLLSL 327
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-327 7.91e-99

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 295.99  E-value: 7.91e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQH 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 TGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPTLLTTMSIM 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 161 SITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPML 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 241 STTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITL-PPNPSSKTKQWSTKS 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMfPSTNNMKMKWQFENT 320


                 ....*...
gi 350430915 320 STNPLIPT 327
Cdd:MTH00105 321 KPMTLLPT 328
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-326 1.52e-82

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 254.12  E-value: 1.52e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQH 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 TGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPTLLTTMSIM 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 161 SITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPML 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 241 STTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITLPPNPSSKTKQWSTKSS 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320


                 ....*.
gi 350430915 321 TNPLIP 326
Cdd:MTH00200 321 SNLLVG 326
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 11-326 6.18e-73

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 229.82  E-value: 6.18e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  11 LSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDITQLT 90
Cdd:MTH00041  11 TSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  91 YPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPTLLTTMSIMSITLGGWMGL 170
Cdd:MTH00041  91 NTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 171 NQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPMLSTTLMLTLLS 250
Cdd:MTH00041 171 NQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILS 250

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 350430915 251 LSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITLPPNPSSKTKQWSTKSSTNPLIP 326
Cdd:MTH00041 251 LGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGV 326
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-325 1.57e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 163.46  E-value: 1.57e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQH 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 TGQWDITQLTyppacaLLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLlttSHSLNPTLLTTMSIM 160
Cdd:MTH00160  82 LMLFNNISSM------LINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILL---SYLINNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 161 SITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPML 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 241 STTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITLPPNPSSKTKQWSTKSS 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFS 312


                 ....*
gi 350430915 321 TNPLI 325
Cdd:MTH00160 313 LILNF 317
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-320 4.71e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 140.79  E-value: 4.71e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  13 ILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDITqltyp 92
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM----- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  93 pacALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLP-PTTLLLTTSHSLNPTLLTTMSIMSITLGGWMGLN 171
Cdd:MTH00144  88 ---SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVApLFLLSNFLDLYWLAYLLCVISVLSALVGSIGGLN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 172 QTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTlMIAWTKAPMLSTTLMLTLLSL 251
Cdd:MTH00144 165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKD-LGSLKPSYKTGLSIISLLLSL 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 350430915 252 SGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTITLPPNPSSKTKQWSTKSS 320
Cdd:MTH00144 244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSI 312
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-310 3.72e-38

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 138.76  E-value: 3.72e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISAlSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVnaqh 80
Cdd:MTH00011   4 TFPTMFLFSS-TMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM---- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 tgQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPTLLTTMSIM 160
Cdd:MTH00011  79 --MWSFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAM 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 161 SITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPML 240
Cdd:MTH00011 157 SALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTT 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 241 STTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYcSTITLPPNPSS 310
Cdd:MTH00011 237 SMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS 305
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 11-302 5.95e-33

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 124.78  E-value: 5.95e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  11 LSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTgqwditqLT 90
Cdd:MTH00197   5 FIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL-------YL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  91 YPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHslNPTLLTTMSIMSITLGGWMGL 170
Cdd:MTH00197  78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGGIGGM 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 171 NQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSVFLTMNTTNTLKLSTLMIAWTKAPMLSTTLMLTLLS 250
Cdd:MTH00197 156 NQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLS 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 350430915 251 LSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAYCSTI 302
Cdd:MTH00197 236 LGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLI 287
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 11-217 5.97e-22

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 96.34  E-value: 5.97e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  11 LSILLGTTLTITSNHWATAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQATASTLVLF--------SSTVN---- 77
Cdd:COG1007  109 LFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNlagi 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  78 AQHTGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKL--------PPTTLLLTTSHSL 149
Cdd:COG1007  189 AAALAAGGANSPLLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaallrLLVEAFPGLAADW 268

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 350430915 150 NPtLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKL----TLLAFFTYTLMTSSVFL 217
Cdd:COG1007  269 QL-LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFA 339
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-296 3.04e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 90.47  E-value: 3.04e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  13 ILLGTTLTITSNHWATAWAGLEINTLSIIPMI-SKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDI----- 86
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLsyinl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  87 --------TQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLttSHSLNPTLLTTMS 158
Cdd:MTH00196  82 vlnsgqsfSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILV--SIGLNVNILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 159 IMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNP----KLTLLAFFTYTLMTSSVFLTMNTTNTLKlsTLMIAW 234
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILALNVYK--NLIIEF 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 350430915 235 T----KAPMLSTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRL 296
Cdd:MTH00196 238 SglsrRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.61e-17

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 81.59  E-value: 1.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   23 SNHWATAWAGLEINTLSIIPMI-SKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDITQL-TYPPACA---- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   97 ------LLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPT------LLTTMSIMSITL 164
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  165 GGWMGLNQTQTRKIMAFSSISHLGWMMVTI----TYNPKLTLLAFFTYTLMTSSVFL--------TMNTTNTLKLSTLmi 232
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsviyrRVHTRNIRDYGGL-- 238

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 350430915  233 aWTKAPMLSTTLMLTLLSLSGLPPLTGFLPKWLIMQ 268
Cdd:pfam00361 239 -AKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-192 5.43e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 81.79  E-value: 5.43e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  14 LLGTTLTITSNHWATAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQATASTLVLF--------SSTVN----AQH 80
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygaTGSLSfagiAKA 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  81 TGQWDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKL--------PPTTLLLTTSHSLNPt 152
Cdd:PRK05777 193 LADGSGNSLLLLFGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafavllrLLVVAFGGLSEDWQQ- 271

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 350430915 153 LLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMV 192
Cdd:PRK05777 272 VLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLV 311
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 11-297 6.17e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.53  E-value: 6.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   11 LSILLGTTLTITSNHWATAWAGLEINTLSI-IPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTV------------- 76
Cdd:TIGR01770 109 LFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLiygftgslnfedl 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   77 -NAQHTGQWDITQLTYppACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTS-------HS 148
Cdd:TIGR01770 189 lLFLSNGMLNISLLLL--GIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfgfSE 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  149 LNPTLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKL----TLLAFFTYTLMTS---SVFLTMNT 221
Cdd:TIGR01770 267 AWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLgafGVLSLLRS 346

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 350430915  222 TN---TLKLSTLMIAWTKAPMLSTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLA 297
Cdd:TIGR01770 347 YKdewIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 14-296 1.55e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 70.95  E-value: 1.55e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  14 LLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDITQL---- 89
Cdd:COG0651  117 LAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLaarl 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  90 -TYPP-----ACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAM---------KLPPTTLLLTTSHSLNPTLL 154
Cdd:COG0651  197 aELDPglllaAFALLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLtkvgvyailRVLTLLFGADPALFLGTLLL 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 155 TtMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTY----TLMTSSVFLT----MNTTNTLK 226
Cdd:COG0651  277 V-LGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhALAKALLFLAagaiERATGTRD 355

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 227 LSTLMIAWTKAPMLSTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRL 296
Cdd:COG0651  356 LDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 11-296 2.55e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 70.43  E-value: 2.55e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  11 LSILLGTTLTITSNHWATAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDITQL 89
Cdd:MTH00199 104 LIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGI 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  90 TYPPAC----ALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPTLLTtmSIMSITLG 165
Cdd:MTH00199 184 NSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIYG 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 166 GWMGLNQTQTRKIMAFSSISHLGWMM--VTITYNPKL--TLLAFFTYTLMTSSVF---LTMNTTNTL--KLSTLMiawTK 236
Cdd:MTH00199 262 AIGALNQTKIKRLLAYSGIGHMGFILfgVAIGSFESIqaSLIYMIIYVIMSICSFsiiLSLKLTKGLivEVSGLS---RK 338

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 237 APMLSTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRL 296
Cdd:MTH00199 339 NPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 2-210 9.39e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 69.12  E-value: 9.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   2 APTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAI---------EAATKYFLVQATASTLVLF 72
Cdd:MTH00198 186 GPRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLF 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  73 SSTVNAQHTGQ--------------WDITQLTYPPACALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPP 138
Cdd:MTH00198 266 GCALYFGFTGNegmlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTV 345

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 350430915 139 TTLLLttSHSLNPTLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTL 210
Cdd:MTH00198 346 YILLT--SLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAV 415
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 38-192 1.06e-08

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 56.24  E-value: 1.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  38 LSIIPM---ISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQW-----DITQLTYPPA-----CALLTIAIAI 104
Cdd:COG1008  142 LMLIPMyflIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfdiaELAAAPLPLTaqlllFLAFFIAFAV 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 105 KLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLP--------PTTLLLTTSHSLNPTLLTtMSIMSITLGGWMGLNQTQTR 176
Cdd:COG1008  222 KVPMFPFHTWLPDAHVEAPTAGSVLLAGVLLKMggygllrfALPLFPEASAYFAPLLAA-LGVIGIIYGALVALAQTDLK 300

                        170
                 ....*....|....*.
gi 350430915 177 KIMAFSSISHLGWMMV 192
Cdd:COG1008  301 RLIAYSSVSHMGFVLL 316
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-220 2.33e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 55.44  E-value: 2.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  50 PRAIEAATKYFLVQATASTLVLFSSTV---------NAQHTGQWDITQLTYPPACALLTIA--IAIKLGLTPFHFWFPEV 118
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYGSSLlyglsggstQLSAIALALITSPSLGLALALVFVIagIAFKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 119 LQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNP-------TLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMM 191
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPsfdeqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316

                        170       180
                 ....*....|....*....|....*....
gi 350430915 192 VTITYNPKLTLLAFFTYTLmtssVFLTMN 220
Cdd:PRK02504 317 IGLVAGTEAGYASMVFYLL----AYLFMN 341
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-298 6.61e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 53.73  E-value: 6.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  33 LEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDITQLT--YPPACALLT------IAIAI 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAgaLAENPTVVTafgfvlLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 105 KLGLTPFHFWFPEVLQG-SSLTTAMLLSTAMK---------LPPTTLLLTTSHSLNPTLLTTMSIMSITLGGWMGLNQTQ 174
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAaPPVVTALLSGLVTKvavyaliriYFTVFGGDFRFALGLGWLLAVLALLSMLVGSLAALGQDD 294

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 175 TRKIMAFSSISHLGWMMVTITYNPKLTLLA----FFTYTLMTSSVFLT----MNTTNTLKLSTLMIAWTKAPMLSTTLML 246
Cdd:PRK08375 295 VKRVLAYSTVSQMGYILLGLALLTPLALAAgllhLLHHALMKGALFLAagaiEVTYGTRRLSELSGLGRRMPLTAAAFAV 374

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 350430915 247 TLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRLAY 298
Cdd:PRK08375 375 ASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-215 6.76e-08

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 53.99  E-value: 6.76e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  13 ILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQATA------STLVLFSSTVNAQHTGQWDI 86
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  87 TQLT-----YPPACALLT-----IAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPT---- 152
Cdd:PRK08676 191 TELAahaslLSPSVLGASflfifIGFLAKSGLVPFHTWLPAAYAKAPSVVSALLSGTVLNIGIYGILRLSALLRQSgaae 270

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 350430915 153 ----LLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTSSV 215
Cdd:PRK08676 271 qfsnVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLAHSLV 337
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 38-194 9.72e-08

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 53.28  E-value: 9.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  38 LSIIPM---ISKSHHPRAIEAATKYFLVQATASTLVLFS----STVNAQHTGQWDITQL---TYPPACALLT-----IAI 102
Cdd:PRK05846 142 AMLIPMyflIGVWGGKNRIYAATKFFLYTLLGSLLMLVAiiylVVVYYNATGTFDIADLlnlPLPPGVQYWLflaffIAF 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 103 AIKLGLTPFHFWFPEVLQ-----GSSLTTAMLLSTA---MKLPPTTLLLTTSHSLNPtLLTTMSIMSITLGGWMGLNQTQ 174
Cdd:PRK05846 222 AVKMPMFPLHTWLPDAHVqaptaGSVLLAGILLKMGaygLLRFSLPLFPDASHEFAP-IIITLGVIAIIYGALVALAQTD 300

                        170       180
                 ....*....|....*....|
gi 350430915 175 TRKIMAFSSISHLGWMMVTI 194
Cdd:PRK05846 301 IKKLIAYSSISHMGFVTLGI 320
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 19-213 1.93e-06

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 49.16  E-value: 1.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  19 LTITSNHWATAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLV------QATASTLVLFSS--------------TVNA 78
Cdd:PRK06458 123 LALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIIcsvgvaFALFGTILVYANaatvmgdgemailwTELL 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  79 QHTGQWDITQLTYppACALLTIAIAIKLGLTPFHFWFPE-----------VLQGSSLTTAMLlstAMKLPPTTLLLTTSH 147
Cdd:PRK06458 203 KHASLLDPTLMKL--AFVFLLIGFGTKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALY---AVLRYYILIDAAIGS 277

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 350430915 148 SLNPTLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTYTLMTS 213
Cdd:PRK06458 278 DFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHS 343
ndhB CHL00049
NADH dehydrogenase subunit 2
 1-263 3.05e-06

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 48.85  E-value: 3.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   1 MAPTTKLISALSILLGTTLTITSNHWATAWAGLEINTLSIIPMISKSHHP-RAIEAATKYFLVQATASTLVL--FSST-- 75
Cdd:CHL00049 108 MAITEFLLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVygFSWLyg 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  76 VNAQHTGQWDI------TQLTYPPAC----ALLTIAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTT 145
Cdd:CHL00049 188 LSGGEIELQEIvnglinTQMYNSPGIsialIFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRI 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 146 SHSLNPT-------LLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMV-TITYNPKLTLLAFFTYTLmtssVFL 217
Cdd:CHL00049 268 FDIPFYFssnewhlLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIgIIVGDSNDGYASMITYML----FYI 343

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 350430915 218 TMN-------TTNTLKLSTLMI-----AWTKAPMLSTTLMLTLLSLSGLPPLTGFLPK 263
Cdd:CHL00049 344 FMNlgtfaciVLFGLRTGTDNIrdyagLYTKDPFLALSLALCLLSLGGIPPLAGFFGK 401
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-194 3.59e-06

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 48.40  E-value: 3.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915   50 PRAIEAATKYFLVQATASTLVLFS----STVNAQHTGQWDITQLTYPPACALLT-----IAIAIKLGLTPFHFWFPEVLQ 120
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAilglYFLGGGTFDLLELLNLPLPFGVQTWLflaffIAFAVKVPLFPLHTWLPDAHV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  121 GSSLTTAMLLSTAMKLPPTTLLLTTSHSLNP-------TLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVT 193
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTYGFLRFNLPLFPdaslyfaPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLG 311


                  .
gi 350430915  194 I 194
Cdd:TIGR01972 312 I 312
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-194 8.73e-06

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 47.33  E-value: 8.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  55 AATKYFLVQATASTLVLFSSTVNAQHTGQ--WDITQLT---YPPACALLT-----IAIAIKLGLTPFHFWFPEVLQGSSL 124
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGaksYPLALELLLyagflIAFGVKLPIFPLHTWLPDAHGEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 350430915 125 TTAMLLSTAMKLP-------PTTLLLTTSHSLNPTLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTI 194
Cdd:PRK12561 218 PVSMILAGVLLKMggyalirFNVQMLPDAHVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGI 294
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 48-196 4.90e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 45.20  E-value: 4.90e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  48 HHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDITQLTYPPAC--------------ALLTIAIAIKLGLTPFHF 113
Cdd:PRK12649 156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELienikghplflitlILIFIGAAAKSAQGPFYI 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 114 WFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPT-----LLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLG 188
Cdd:PRK12649 236 WLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSGTeawfiLVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQLA 315


                 ....*...
gi 350430915 189 WMMVTITY 196
Cdd:PRK12649 316 YLMTMYGY 323
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 6.73e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 44.70  E-value: 6.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  33 LEINTLSIIPMIS-KSHHPRAIEAATKYFLVQATASTLVLFSStvnAQHTGQWDITQLTYPP-------------ACALL 98
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYLAvkmsenptvvakiALALF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  99 TIAIAIKLGLTPFHFWFPEVL-QGSSLTTAMLLSTAMKLPPTTLLLTTS---HSLNPT----LLTTMSIMSITLGGWMGL 170
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWLPDAYpAAPSSISAMLLVIKQAGLYALARVLFSiygPAINLAtvgwVIIILGCLTMFVGVAMAV 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 171 NQTQTRKIMAFSSISHLGWMM------VTITYNPKLTLLAF----------FTYTLMTSSVFLT----MNTTNTLKLSTL 230
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMLlglgvgLAALGDPAMASYGEialaggiyhiVNHALYKALLFLTagavIYETGTRNLNEL 386

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 350430915 231 MIAWTKAPMLSTTLMLTLLSLSGLPPLTGFLPKWLI 266
Cdd:PRK08376 387 GGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 79-204 9.28e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 44.14  E-value: 9.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  79 QHTGQWDITQL-TYPPACALLTIAIAI-------KLGLTPFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTS---H 147
Cdd:PRK12644 182 QAAGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVARLApgfA 261

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 350430915 148 SLNPTLLTTMSIMSIT--LGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLA 204
Cdd:PRK12644 262 DVPVWRPTVLVLGLATmlLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALA 320
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 10-273 1.56e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 43.45  E-value: 1.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  10 ALSILLGTTLTITSNHWATAWAGLEINTLS---IIPMISKshhpRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDI 86
Cdd:PRK08668 104 ALMSLAGVLGVFLANDLLTLYIFWEIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDF 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  87 ----------TQLTYPPACALLTIAIAI-KLGLTPFHFWFPE-----------VLQGS---------SLTTAMLLSTAMk 135
Cdd:PRK08668 180 adisqglindTSTGFALIVFLFLLAFGVaKAGIFPLHVWAPDayseapqsfsaVLSGQlsklgaygfLLVLYVLPGTKL- 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 136 lpPTTLLLTTSHSLNPTLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYnpkLTLLAF-------FTY 208
Cdd:PRK08668 259 --FSEFGTYRGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGL---GTSLGFagglfhvFNH 333

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 350430915 209 TLMTSSVFLTMNT----TNTLKLSTLMIAWTKAPMLSTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQ 273
Cdd:PRK08668 334 ALFKGLFFLIFAAviyrTGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISK 402
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 48-192 3.01e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 42.45  E-value: 3.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  48 HHPRAIEAATKYFLV---------------QATASTLVLfsSTVNAQhtGQWDITQLTYPPACALLTIAIAIKLGLTPFH 112
Cdd:COG1009  156 EKPSARRAARKAFLVtrvgdlglllgilllGAIAGTLNF--SELLAA--APTILSSPLLTLILLLLLLGAFGKSAQFPLH 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 113 FWFPEVLQG----SSL----T--TA-----MLLSTAMklppttlllttshSLNPTLLTTMSIM-SITL--GGWMGLNQTQ 174
Cdd:COG1009  232 FWLPDAMEGptpvSALlhaaTmvKAgvyllARLSPLF-------------ALSPVWLTVVAIIgAITAlfAALIALAQTD 298

                        170
                 ....*....|....*...
gi 350430915 175 TRKIMAFSSISHLGWMMV 192
Cdd:COG1009  299 IKRVLAYSTVSQLGYMFL 316
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-271 1.55e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 40.32  E-value: 1.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  33 LEINTLSIIPMISKSHHPRAIEAATKYFLVQATASTLVLFSSTVNAQHTGQWDITQLTY--PPACALLTIAIAIKLGLTP 110
Cdd:PRK07234 123 LEVLSIATFLLVAYPRTDRAIWVGLRYLFYSNVAMLFYLIGAVLVYQANGTFAFSGLATadPEAFALIALGLLVKGGIFV 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 111 FHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTSHSLNPT--LLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLG 188
Cdd:PRK07234 203 SGLWLPLTHSEAEPPVSALLSGVVVKAGVFPLVRCALDVPGLdlIVRIFGVGTALLGVLFALLEKDLKRMLAFSTISQLG 282

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 189 WMMVTitynPKLTLLAFFTYTLMTSSVFL---TMNTTNTLKLSTLMIAWTKAPMLSTTLMLTLLSLsglpPLTGFLPKWL 265
Cdd:PRK07234 283 FILAA----PLVGGLYALAHGLVKSTLFLcagALPSRNFTELISQMLGIGKWIPLTMASFSIAGFP----LLAGFVSKVL 354


                 ....*.
gi 350430915 266 IMQELI 271
Cdd:PRK07234 355 TLKNLL 360
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
55-204 2.52e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 39.68  E-value: 2.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  55 AATKYFLVQATASTLVL--FSSTVNAQHTGQWDITQL---TYPPACALL-----TIAIAIKLGLTPFHFWFPEVLQGSSL 124
Cdd:PRK06473 158 AATKFLLYTAISGILILvsFLGLVWLSGASSFDYEPLrshTLPLSTQLLllapiLVGFGIKIPLVPFHTWLPDAHVEAST 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 125 TTAMLLSTAMKLPPTTLLLTTSHSLNPTL-------LTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYN 197
Cdd:PRK06473 238 PVSVLLAGVLLKLGTYGLLRFGVGLFPEAwvylapwLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILLAAAAA 317


                 ....*..
gi 350430915 198 PKLTLLA 204
Cdd:PRK06473 318 TPLSILA 324
PRK12650 PRK12650
DUF4040 family protein;
110-218 2.92e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 39.64  E-value: 2.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 110 PFHFWFPEVLQGSSLTTAMLLSTAMKLPPTTLLLTTS--HSLNPT---LLTTMSIMSITLGGWMGLNQTQTRKIMAFSSI 184
Cdd:PRK12650 226 PFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSpvFHDVAVwnwLLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 350430915 185 SHLGWMMVTITYNPKLTLLAFFTYT----LMTSSVFLT 218
Cdd:PRK12650 306 SQLGWIVATIGVGTPFALTAAVVHTlahaLFKSSLFML 343
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 59-194 5.32e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 38.56  E-value: 5.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915  59 YFLVQATASTLVLFSSTVNA-QHTGQWDITQLTYPPAC-----ALLTIAIAIKLGLTPFHFWFPEVLQG-----SSLTTA 127
Cdd:PRK08667 166 FYFVMTQLSTVFLMLGIIVLfIQTGSFELSPLGASAGIlslvfLLLFLGFGIKAGIIPFHKWLPYAHPAspsnvSALMSG 245

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 350430915 128 MLLSTAMKLPPTTLLLTTSHSLN-PTLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTI 194
Cdd:PRK08667 246 VMLKVAVYGLVRFLMDVLSPELWwGVLILLAGSISALLGVIYALKEHDLKGLLAYSSIENIGIILMGI 313
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 152-296 5.84e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 38.56  E-value: 5.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 152 TLLTTMSIMSITLGGWMGLNQTQTRKIMAFSSISHLGWMMVTITYNPKLTLLAFFTY----TLMTSSVFLTMNTT----N 223
Cdd:PRK12662 280 NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFMVSGSIsyhfG 359

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 350430915 224 TLKLSTLMIAWTKAPMLSTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTATTISMLSLLGLFFYLRL 296
Cdd:PRK12662 360 TTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVLLVGSGLSVIYVWKI 432
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 100-194 7.54e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 37.98  E-value: 7.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430915 100 IAIAIKLGLTPFHFWFPEV-----LQGSSLTTAMLLST---AMKLPPTTLLLTTSHSLNPTLLtTMSIMSITLGGWMGLN 171
Cdd:MTH00226 238 LAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILLKLggyGLVRLSWPILPLGAQNLAPAVI-AMGIVGIVYGSFATCR 316

                         90       100
                 ....*....|....*....|...
gi 350430915 172 QTQTRKIMAFSSISHLGWMMVTI 194
Cdd:MTH00226 317 QIDVKRLVAYSSVAHMGLVSITL 339
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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