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Conserved domains on  [gi|350430923|gb|AEQ28429|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Hapalopsittaca melanotis peruviana]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 3.57e-141

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 403.43  E-value: 3.57e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   1 MTPTTKLISTMSILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 TGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTTMSIM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 161 SIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 241 NTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITLPPNPSSKIKQWFTKNP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 350430923 321 TNPLISTLTSLSTLLLPLSPMILTIT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 3.57e-141

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 403.43  E-value: 3.57e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   1 MTPTTKLISTMSILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 TGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTTMSIM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 161 SIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 241 NTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITLPPNPSSKIKQWFTKNP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 350430923 321 TNPLISTLTSLSTLLLPLSPMILTIT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-298 1.35e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 95.18  E-value: 1.35e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  10 TMSILLGTMITITSNHWAMAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQAAASTLVLF--------SSTVN--- 77
Cdd:COG1007  108 LLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNlag 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  78 -AQHTGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKL----PPTTLLLITSHSLNPA 152
Cdd:COG1007  188 iAAALAAGGANSPLLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPGLAAD 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 153 ---LLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKL----TLLAFLTYTLMTSSIF-----LT** 220
Cdd:COG1007  268 wqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFavillLSRK 347

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 350430923 221 TTNTLKLSTLMTSWTKAPMLNTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAY 298
Cdd:COG1007  348 GGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-217 6.18e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 82.75  E-value: 6.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   23 SNHWAMAWAGLEINTLSIIPMI-SKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDITQL-TYPPAC----- 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   96 -----VLLTTAIAIKLGLTPFHFWFPEVLQGSSLT-TAMLLSTVMKLPP---TTLLLITSHSLNPA--LLTTMSIMSIAL 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGyglIRRSLLYLPSSPFIqqILLILAIISMLL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 350430923  165 GGWMGLNQTQIRKIMAFSSISHLGWMMITI----TYNPKLTLLAFLTYTLMTSSIFL 217
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFL 217
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 13-297 6.46e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 84.23  E-value: 6.46e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   13 ILLGTMITITSNHWAMAWAGLEINTLSI-IPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTV--------------N 77
Cdd:TIGR01770 111 ALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLiygftgslnfedllL 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   78 AQHTGQWDITQLTYppACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLL-------ITSHSLN 150
Cdd:TIGR01770 191 FLSNGMLNISLLLL--GIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGFSEAW 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  151 PALLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKL----TLLAFLTYTLMTSSIFLT**TTNTLK 226
Cdd:TIGR01770 269 QIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSLLRSYK 348

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 350430923  227 ------LSTLMTSWTKAPMLNTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLA 297
Cdd:TIGR01770 349 dewieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 3.57e-141

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 403.43  E-value: 3.57e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   1 MTPTTKLISTMSILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 TGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTTMSIM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 161 SIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 241 NTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITLPPNPSSKIKQWFTKNP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 350430923 321 TNPLISTLTSLSTLLLPLSPMILTIT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-325 6.26e-112

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 329.19  E-value: 6.26e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   1 MTPTTKLISTMSILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQH 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 TGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTTMSIM 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 161 SIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPML 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 241 NTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITLPPNPSSKIKQWFTKNP 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320


                 ....*
gi 350430923 321 TNPLI 325
Cdd:MTH00070 321 TNNLL 325
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-324 1.71e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 328.30  E-value: 1.71e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   1 MTPTTKLISTMSILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQH 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 TGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSlNPALLTTMSIM 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 161 SIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPML 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 241 NTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITLPPNPSSKIKQWFTKNP 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319


                 ....
gi 350430923 321 TNPL 324
Cdd:MTH00135 320 QLTL 323
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-325 2.37e-99

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 297.14  E-value: 2.37e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   1 MTPTTKLISTMSILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQH 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 TGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTTMSIM 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 161 SIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPML 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 241 NTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITL-PPNPSSKIKQWFTKN 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMfPSTNNMKMKWQFENT 320


                 ....*.
gi 350430923 320 PTNPLI 325
Cdd:MTH00105 321 KPMTLL 326
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 4.21e-82

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 253.35  E-value: 4.21e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   1 MTPTTKLISTMSILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQH 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 TGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTTMSIM 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 161 SIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPML 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 241 NTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITLPPNPSSKIKQWFTKNP 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*.
gi 350430923 321 TNPLISTLTSLSTLLLPLSPMILTIT 346
Cdd:MTH00200 321 SNLLVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 12-325 1.31e-73

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 231.36  E-value: 1.31e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  12 SILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDITQLTY 91
Cdd:MTH00041  12 SIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  92 PPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTTMSIMSIALGGWMGLN 171
Cdd:MTH00041  92 TLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLN 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 172 QTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPMLNTTLMLTLLSL 251
Cdd:MTH00041 172 QTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSL 251

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 350430923 252 SGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITLPPNPSSKIKQWFTKNPTNPLI 325
Cdd:MTH00041 252 GGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYG 325
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-313 1.60e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 166.15  E-value: 1.60e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   1 MTPTTKLISTMSILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQh 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 tgqwdITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLlitSHSLNPALLTTMSIM 160
Cdd:MTH00160  81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILL---SYLINNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 161 SIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPML 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 350430923 241 NTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITLPPNPSSKIK 313
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLK 305
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-310 1.55e-39

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 142.23  E-value: 1.55e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   1 MTPTTKLISTMSILlGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVnaqh 80
Cdd:MTH00011   4 TFPTMFLFSSTMTL-GTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM---- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 tgQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTTMSIM 160
Cdd:MTH00011  79 --MWSFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAM 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 161 SIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPML 240
Cdd:MTH00011 157 SALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTT 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 241 NTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYcSTITLPPNPSS 310
Cdd:MTH00011 237 SMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS 305
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 6-315 1.67e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 142.33  E-value: 1.67e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   6 KLISTMSILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWD 85
Cdd:MTH00144   6 NLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  86 ITqltyppacVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPttLLLITSHSLNPALLTT---MSIMSI 162
Cdd:MTH00144  86 SM--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAP--LFLLSNFLDLYWLAYLlcvISVLSA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 163 ALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTlMTSWTKAPMLNT 242
Cdd:MTH00144 156 LVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKD-LGSLKPSYKTGL 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 350430923 243 TLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTITLPPNPSSKIKQW 315
Cdd:MTH00144 235 SIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-302 6.70e-34

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 127.10  E-value: 6.70e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  12 SILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTgqwditqLTY 91
Cdd:MTH00197   6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL-------YLS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  92 PPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPttLLLITSHSLNPALLTTMSIMSIALGGWMGLN 171
Cdd:MTH00197  79 LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGGIGGMN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 172 QTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSIFLT**TTNTLKLSTLMTSWTKAPMLNTTLMLTLLSL 251
Cdd:MTH00197 157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 350430923 252 SGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAYCSTI 302
Cdd:MTH00197 237 GGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLI 287
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-298 1.35e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 95.18  E-value: 1.35e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  10 TMSILLGTMITITSNHWAMAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQAAASTLVLF--------SSTVN--- 77
Cdd:COG1007  108 LLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNlag 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  78 -AQHTGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKL----PPTTLLLITSHSLNPA 152
Cdd:COG1007  188 iAAALAAGGANSPLLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPGLAAD 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 153 ---LLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKL----TLLAFLTYTLMTSSIF-----LT** 220
Cdd:COG1007  268 wqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFavillLSRK 347

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 350430923 221 TTNTLKLSTLMTSWTKAPMLNTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAY 298
Cdd:COG1007  348 GGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-296 1.47e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 93.94  E-value: 1.47e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  13 ILLGTMITITSNHWAMAWAGLEINTLSIIPMI-SKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDI----- 86
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLsyinl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  87 --------TQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLppTTLLLITSHSLNPALLTTMS 158
Cdd:MTH00196  82 vlnsgqsfSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKL--GIFSILVSIGLNVNILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 159 IMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLM--TSSIFLT**TTNTLKLSTLMTSWT- 235
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSFESIQASLVYLFIyiIMSICVFSIILALNVYKNLIIEFSg 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 350430923 236 ---KAPMLNTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRL 296
Cdd:MTH00196 240 lsrRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-192 8.55e-20

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 89.88  E-value: 8.55e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  14 LLGTMITITSNHWAMAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQAAASTLVLF--------SSTVN----AQH 80
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygaTGSLSfagiAKA 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  81 TGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKL----PPTTLLLITSHSLNPA---L 153
Cdd:PRK05777 193 LADGSGNSLLLLFGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwqqV 272

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 350430923 154 LTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMI 192
Cdd:PRK05777 273 LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLV 311
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-217 6.18e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 82.75  E-value: 6.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   23 SNHWAMAWAGLEINTLSIIPMI-SKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDITQL-TYPPAC----- 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   96 -----VLLTTAIAIKLGLTPFHFWFPEVLQGSSLT-TAMLLSTVMKLPP---TTLLLITSHSLNPA--LLTTMSIMSIAL 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGyglIRRSLLYLPSSPFIqqILLILAIISMLL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 350430923  165 GGWMGLNQTQIRKIMAFSSISHLGWMMITI----TYNPKLTLLAFLTYTLMTSSIFL 217
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFL 217
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 13-297 6.46e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 84.23  E-value: 6.46e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   13 ILLGTMITITSNHWAMAWAGLEINTLSI-IPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTV--------------N 77
Cdd:TIGR01770 111 ALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLiygftgslnfedllL 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   78 AQHTGQWDITQLTYppACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLL-------ITSHSLN 150
Cdd:TIGR01770 191 FLSNGMLNISLLLL--GIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGFSEAW 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  151 PALLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKL----TLLAFLTYTLMTSSIFLT**TTNTLK 226
Cdd:TIGR01770 269 QIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSLLRSYK 348

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 350430923  227 ------LSTLMTSWTKAPMLNTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLA 297
Cdd:TIGR01770 349 dewieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-296 3.90e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 75.82  E-value: 3.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  13 ILLGTMITITSNHWAMAWAGLEINTLSIIPMIS-KSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDITQLTY 91
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  92 PPAC----VLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTtmSIMSIALGGW 167
Cdd:MTH00199 186 ILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIYGAI 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 168 MGLNQTQIRKIMAFSSISHLGWMMITITYNP----KLTLLAFLTYTLMTSSIF-----LT**TTNTLKLSTLMTswtKAP 238
Cdd:MTH00199 264 GALNQTKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSICSFsiilsLKLTKGLIVEVSGLSR---KNP 340

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 350430923 239 MLNTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRL 296
Cdd:MTH00199 341 VIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-210 3.75e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 73.35  E-value: 3.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  15 LGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAI---------EAATKYFLVQAAASTLVLFSSTVNAQHTGQ-- 83
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNeg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  84 ------------WDITQLTYPPACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLppTTLLLITSHSLNP 151
Cdd:MTH00198 279 mlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITS 356

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 350430923 152 ALLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTL 210
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAV 415
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 14-296 6.61e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 69.02  E-value: 6.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  14 LLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDITQL---- 89
Cdd:COG0651  117 LAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLaarl 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  90 -TYPP-----ACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVM-KLPP----TTLLLITSHSLNPA---LLT 155
Cdd:COG0651  197 aELDPglllaAFALLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLtKVGVyailRVLTLLFGADPALFlgtLLL 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 156 TMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTY----TLMTSSIFLT----**TTNTLKL 227
Cdd:COG0651  277 VLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhALAKALLFLAagaiERATGTRDL 356

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 350430923 228 STLMTSWTKAPMLNTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRL 296
Cdd:COG0651  357 DKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 38-192 1.04e-11

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 65.49  E-value: 1.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  38 LSIIPM---ISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQW-----DITQLTYPPA-----CVLLTTAIAI 104
Cdd:COG1008  142 LMLIPMyflIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfdiaELAAAPLPLTaqlllFLAFFIAFAV 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 105 KLGLTPFHFWFPEVLQGSSLTTAMLLSTVMK-----------LPpttLLLITSHSLNPALLTtMSIMSIALGGWMGLNQT 173
Cdd:COG1008  222 KVPMFPFHTWLPDAHVEAPTAGSVLLAGVLLkmggygllrfaLP---LFPEASAYFAPLLAA-LGVIGIIYGALVALAQT 297

                        170
                 ....*....|....*....
gi 350430923 174 QIRKIMAFSSISHLGWMMI 192
Cdd:COG1008  298 DLKRLIAYSSVSHMGFVLL 316
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-210 2.43e-10

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 61.56  E-value: 2.43e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  51 RAIEAATKYFLVQAAASTLVL--FSST--VNAQHTGQWDI------TQLTYPPAC----VLLTTAIAIKLGLTPFHFWFP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVygFSWLygLSGGEIELQEIvnglinTQMYNSPGIsialIFITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 117 EVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSLNPA-------LLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGW 189
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYFssnewhlLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180
                 ....*....|....*....|..
gi 350430923 190 MMI-TITYNPKLTLLAFLTYTL 210
Cdd:CHL00049 319 VIIgIIVGDSNDGYASMITYML 340
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
15-192 6.35e-10

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 60.06  E-value: 6.35e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  15 LGTMITITSNHWAMAWAGLEinTLSIIPMISKSH---HPRAIEAATKYFLVQAAASTLVLFSST----VNAQHTGQWDIT 87
Cdd:PRK02504 121 LGGMFLSGATELVMIFISLE--TLSIASYLLTGYmkrDPRSNEAALKYLLIGAASSAIFLYGSSllygLSGGSTQLSAIA 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  88 Q-LTYPP------ACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTL---LLITSHSLNP----AL 153
Cdd:PRK02504 199 LaLITSPslglalALVFVIAGIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALairLLVTAFPSFDeqwkLL 278

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 350430923 154 LTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMI 192
Cdd:PRK02504 279 FTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMI 317
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 12-213 9.00e-09

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 56.48  E-value: 9.00e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  12 SILLGTM-ITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSS---------------- 74
Cdd:PRK06458 115 QLFLFTMlLALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTilvyanaatvmgdgem 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  75 ----TVNAQHTGQWDITQLTYppACVLLTTAIAIKLGLTPFHFWFPEV-LQGSSLTTAMlLSTVmkLPPTTLL------L 143
Cdd:PRK06458 195 ailwTELLKHASLLDPTLMKL--AFVFLLIGFGTKVGLFPMHAWLPDAhSEAPSPVSAL-LSGV--LLNVALYavlryyI 269

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 350430923 144 ITSHSLNPA----LLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTS 213
Cdd:PRK06458 270 LIDAAIGSDfpgrLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHS 343
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 38-194 1.59e-08

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 55.98  E-value: 1.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  38 LSIIPM---ISKSHHPRAIEAATKYFLVQAAASTLVLFS----STVNAQHTGQWDITQLTYPPACVLLTT--------AI 102
Cdd:PRK05846 142 AMLIPMyflIGVWGGKNRIYAATKFFLYTLLGSLLMLVAiiylVVVYYNATGTFDIADLLNLPLPPGVQYwlflaffiAF 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 103 AIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVM-KLPPTTLLLI-------TSHSLNPaLLTTMSIMSIALGGWMGLNQTQ 174
Cdd:PRK05846 222 AVKMPMFPLHTWLPDAHVQAPTAGSVLLAGILlKMGAYGLLRFslplfpdASHEFAP-IIITLGVIAIIYGALVALAQTD 300

                        170       180
                 ....*....|....*....|
gi 350430923 175 IRKIMAFSSISHLGWMMITI 194
Cdd:PRK05846 301 IKKLIAYSSISHMGFVTLGI 320
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-215 1.67e-08

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 55.92  E-value: 1.67e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  13 ILLGTMITITSNHWAMAWAGLEINTLSIIPMISKSHHPRAIEAATKYFLVQAAA------STLVLFSSTVNAQHTGQWDI 86
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  87 TQLT-----YPPACVLLT-----TAIAIKLGLTPFHFWFPEV-LQGSSLTTAMLLSTVMKLPPTTLLLITS-------HS 148
Cdd:PRK08676 191 TELAahaslLSPSVLGASflfifIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRLSAllrqsgaAE 270

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 350430923 149 LNPALLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYTLMTSSI 215
Cdd:PRK08676 271 QFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLAHSLV 337
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-298 2.50e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 55.27  E-value: 2.50e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  33 LEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDITQLT--YPPACVLLT------TAIAI 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAgaLAENPTVVTafgfvlLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 105 KLGLTPFHFWFPEVLQG-SSLTTAMLLSTVMKLPPTTLLLITSH----------SLNPALLTTMsIMSIALGGWMGLNQT 173
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAaPPVVTALLSGLVTKVAVYALIRIYFTvfggdfrfalGLGWLLAVLA-LLSMLVGSLAALGQD 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 174 QIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYT----LMTSSIFLT*----*TTNTLKLSTLMTSWTKAPMLNTTLM 245
Cdd:PRK08375 294 DVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLlhhaLMKGALFLAAgaieVTYGTRRLSELSGLGRRMPLTAAAFA 373

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 350430923 246 LTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRLAY 298
Cdd:PRK08375 374 VASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-194 8.45e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 53.40  E-value: 8.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923   50 PRAIEAATKYFLVQAAASTLVLFSSTVNA-QHTGQWDITQLTYPPACVLLTT--------AIAIKLGLTPFHFWFPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYfLGGGTFDLLELLNLPLPFGVQTwlflaffiAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  120 QGSSLTTAMLLSTVMKLPPTTLLLI-------TSHSLNPaLLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMI 192
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTYGFLRFnlplfpdASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310


                  ..
gi 350430923  193 TI 194
Cdd:TIGR01972 311 GI 312
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-194 2.04e-07

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 52.34  E-value: 2.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  55 AATKYFLVQAAASTLVLFSSTVNAQHTGQ--WDITQLT---YPPACVLLT-----TAIAIKLGLTPFHFWFPEVLQGSSL 124
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGaksYPLALELLLyagflIAFGVKLPIFPLHTWLPDAHGEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 350430923 125 TTAMLLSTVM-KLPPTTL------LLITSHSLNPALLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITI 194
Cdd:PRK12561 218 PVSMILAGVLlKMGGYALirfnvqMLPDAHVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGI 294
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 48-196 2.15e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 46.36  E-value: 2.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  48 HHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDITQLTYPPACV--------LLTTAIAIKLGLT------PFHF 113
Cdd:PRK12649 156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELIenikghplFLITLILIFIGAAaksaqgPFYI 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 114 WFPEVLQGSSLTTAMLLSTVMkLPPTTLLLITSH---SLNPA---LLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHL 187
Cdd:PRK12649 236 WLPNAMEAPTPVSAFLHSATM-VKAGVYLVARIHpifSGTEAwfiLVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQL 314


                 ....*....
gi 350430923 188 GWMMITITY 196
Cdd:PRK12649 315 AYLMTMYGY 323
PRK12650 PRK12650
DUF4040 family protein;
96-217 4.32e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 45.42  E-value: 4.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  96 VLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLLLITSHSL--NPA---LLTTMSIMSIALGGWMGL 170
Cdd:PRK12650 212 VLIAVAAFTKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFhdVAVwnwLLIIVGMITALMGAVFAV 291

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 350430923 171 NQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTYT----LMTSSIFL 217
Cdd:PRK12650 292 QKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTlahaLFKSSLFM 342
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 48-192 6.04e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 44.76  E-value: 6.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  48 HHPRAIEAATKYFLVQAA------ASTLVLFS-------STVNAQhtGQWDITQLTYPPACVLLTTAIAIKLGLTPFHFW 114
Cdd:COG1009  156 EKPSARRAARKAFLVTRVgdlgllLGILLLGAiagtlnfSELLAA--APTILSSPLLTLILLLLLLGAFGKSAQFPLHFW 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 115 FPEVLQG----SSL----T--TA-----MLLSTVMKLPPTTLLLItshslnpallTTMSIMSIALGGWMGLNQTQIRKIM 179
Cdd:COG1009  234 LPDAMEGptpvSALlhaaTmvKAgvyllARLSPLFALSPVWLTVV----------AIIGAITALFAALIALAQTDIKRVL 303

                        170
                 ....*....|...
gi 350430923 180 AFSSISHLGWMMI 192
Cdd:COG1009  304 AYSTVSQLGYMFL 316
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 59-194 2.15e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 43.18  E-value: 2.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  59 YFLVQAAASTLVLFSSTVNA-QHTGQWDITQLTYPPAC-----VLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLST 132
Cdd:PRK08667 166 FYFVMTQLSTVFLMLGIIVLfIQTGSFELSPLGASAGIlslvfLLLFLGFGIKAGIIPFHKWLPYAHPASPSNVSALMSG 245

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 350430923 133 VM-KLPPTTLLLITSHSLNP-----ALLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITI 194
Cdd:PRK08667 246 VMlKVAVYGLVRFLMDVLSPelwwgVLILLAGSISALLGVIYALKEHDLKGLLAYSSIENIGIILMGI 313
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 34-273 2.86e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 42.68  E-value: 2.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  34 EINTLS---IIPMISKshhpRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDI----------TQLTYPPACVLLTT 100
Cdd:PRK08668 128 EIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFadisqglindTSTGFALIVFLFLL 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 101 AIAI-KLGLTPFHFWFPE-----------VLQGS-SLTTAMLLSTVMKLPPTTLLLIT-----SHSLNPALLTTMSIMSI 162
Cdd:PRK08668 204 AFGVaKAGIFPLHVWAPDayseapqsfsaVLSGQlSKLGAYGFLLVLYVLPGTKLFSEfgtyrGVPLFNYILAWLGNISI 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 163 ALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYnpkLTLLAF-------LTYTLMTSSIFLT**TTN----TLKLSTLM 231
Cdd:PRK08668 284 IVGTLMAILQEDIKKLIAYSSVANGGYILVGLGL---GTSLGFagglfhvFNHALFKGLFFLIFAAVIyrtgTTKISEMG 360

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 350430923 232 TSWTKAPMLNTTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQ 273
Cdd:PRK08668 361 GLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISK 402
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
96-204 6.08e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 41.61  E-value: 6.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  96 VLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVM-KLPPTTLL------LITSHSLNPALLTTMSIMSIALGGWM 168
Cdd:PRK06473 209 APILVGFGIKIPLVPFHTWLPDAHVEASTPVSVLLAGVLlKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASC 288

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 350430923 169 GLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLA 204
Cdd:PRK06473 289 AIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILA 324
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 101-194 6.93e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 41.45  E-value: 6.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 101 AIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTV-MKLPPTTLLLIT-------SHSLNPALLtTMSIMSIALGGWMGLNQ 172
Cdd:MTH00226 239 AMAVKIPIFPFHIWLPKAHVEAPVAGSVLLAGIlLKLGGYGLVRLSwpilplgAQNLAPAVI-AMGIVGIVYGSFATCRQ 317

                         90       100
                 ....*....|....*....|..
gi 350430923 173 TQIRKIMAFSSISHLGWMMITI 194
Cdd:MTH00226 318 IDVKRLVAYSSVAHMGLVSITL 339
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
10-194 8.83e-04

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 40.84  E-value: 8.83e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  10 TMSILLGTMITITSNHWAM---AWAGLEI---NTLSIIPmisksHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQ 83
Cdd:PRK08168 106 LAGVLAAVHLLVLSDHLLVliaAWAAISLalhRLLCFYP-----DRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGS 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  84 WDITQL-----TYPP------ACVLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPPTTLL----LITSHS 148
Cdd:PRK08168 181 LSLSALwahlaAQGAspslqaAALLLVLAVILKTAQLPVHGWLIQVMEAPTPVSALLHAGVVNLGGFVLIrfapLLEQAP 260

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 350430923 149 LNPALLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITI 194
Cdd:PRK08168 261 PARWLLVLVGLATAVLAGLVMLTRISIKVRLAWSTVAQMGFMLLEC 306
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 1.31e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 40.47  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  33 LEINTLSIIPMIS-KSHHPRAIEAATKYFLVQAAASTLVLFSStvnAQHTGQWDITQLTYPP-------------ACVLL 98
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYLAvkmsenptvvakiALALF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  99 TTAIAIKLGLTPFHFWFPEVLQG--SSLTTAMLLSTVMKLPPTTLLLITSHSLNPALLTTMSIMSI------ALGGWMGL 170
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWLPDAYPAapSSISAMLLVIKQAGLYALARVLFSIYGPAINLATVGWVIIIlgcltmFVGVAMAV 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 171 NQTQIRKIMAFSSISHLGWMM------ITITYNPKLTLLAFLT----------YTLMTSSIFLT**TTN----TLKLSTL 230
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMLlglgvgLAALGDPAMASYGEIAlaggiyhivnHALYKALLFLTAGAVIyetgTRNLNEL 386

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 350430923 231 MTSWTKAPMLNTTLMLTLLSLSGLPPLTGFLPKWLI 266
Cdd:PRK08376 387 GGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-296 2.74e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 39.33  E-value: 2.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  33 LEINTLSIIPMISKSHHPRAIEAATKYFLVQAAASTLVLFSSTVNAQHTGQWDITQL-----------TYPPACVLLTTA 101
Cdd:PRK12662 139 LEISSISSYVLVAMGRDKKALVAAFEYLIIGTIGATFYLIGIGFLYAITGTLNMGDMfliiqdlptnrAIQIGVLFIMVG 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 102 IAIKLGLTPFHFW----------FPEVLQGSSLTTAM--LLSTVMKLPPTTLLLITSHSLNPALLTtMSIMSIALGGWMG 169
Cdd:PRK12662 219 LFIKAALFPFHKWliqayseapsFISVFFSGTSTKVMiyLIIRIVYDVFKANFVFTTLPFNNVFMI-LAALAIVFGSVLA 297

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 170 LNQTQIRKIMAFSSISHLGWMMITITYNPKLTLLAFLTY----TLMTSSIFLT**TTN----TLKLSTLMTSWTKAPMLN 241
Cdd:PRK12662 298 ILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFMVSGSISyhfgTTKLEDCLNLWKSMPKIT 377

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 350430923 242 TTLMLTLLSLSGLPPLTGFLPKWLIMQELIKQETTTTTTIISMLSLLGLFFYLRL 296
Cdd:PRK12662 378 LAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVLLVGSGLSVIYVWKI 432
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
96-203 3.01e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 39.31  E-value: 3.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  96 VLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVM-KLPPTTLLLI-------TSHSLNPALLTTMSImSIALGGW 167
Cdd:PRK07363 209 TGLLLGFGIKIPLVPLHTWLPDAYTEASPAVAILLGGVLaKLGTYGLLRFglqlfpqTWSLVAPGLAIIGTI-SVIYGAL 287

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 350430923 168 MGLNQTQIRKIMAFSSISHLGWMMITITYNPKLTLL 203
Cdd:PRK07363 288 SAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLL 323
ndhD CHL00011
NADH dehydrogenase subunit 4
 101-194 3.64e-03

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 39.16  E-value: 3.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 101 AIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVM-KLPPTTL------LLITSHSLNPALLTTMSIMSIALGGWMGLNQT 173
Cdd:CHL00011 220 AYAVKLPIIPLHTWLPDTHGEAHYSTCMLLAGILlKMGAYGLirinmeLLPHAHSIFSPWLVIVGAIQIIYAASTSLGQR 299

                         90       100
                 ....*....|....*....|.
gi 350430923 174 QIRKIMAFSSISHLGWMMITI 194
Cdd:CHL00011 300 NLKKRIAYSSVSHMGFIIIGI 320
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-194 4.32e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 38.92  E-value: 4.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  55 AATKYFLVQAAASTLVL--------FSSTVNAQHTgqwDITQLTYPPACVLLT-----TAIAIKLGLTPFHFWFPEVLQG 121
Cdd:PRK02546 166 AATKFILYTAGSSLFILlaalamafYGDTPTFDMT---ALAAKDFGLGFQLLCyagllIAYGVKLPIVPLHTWLPDAHGE 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 122 SSLTTAMLLSTVM-KLPPTTLL------LITSHSLNPALLTTMSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITI 194
Cdd:PRK02546 243 ATAPVHMLLAGILlKMGGYALLrmnagmLPDAHAQFAPLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGI 322
ND5 MTH00066
NADH dehydrogenase subunit 5; Provisional
 78-206 5.24e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214416 [Multi-domain]  Cd Length: 598  Bit Score: 38.74  E-value: 5.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923  78 AQHTGQWDITQ--LTYPPACVLL---TTAIAIKLGLTPFHFWFPEVLQGSSLTTAMLLSTVMKLPpTTLLLITSHSL--- 149
Cdd:MTH00066 188 AMNTNSWELQQifLLNDNSTLPLlglILAAAGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVA-GIFLLIRFHPLlen 266

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 350430923 150 NPALLTT---MSIMSIALGGWMGLNQTQIRKIMAFSSISHLGWMMITITYNpkLTLLAFL 206
Cdd:MTH00066 267 NQTALTIclcLGALTTLFTAACALTQNDIKKIVAFSTSSQLGLMMVTIGLN--QPQLAFF 324
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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