NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|383215307|gb|AFG73167|]
View 

NADH dehydrogenase subunit 2, partial (mitochondrion) [Caryanda elegans]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 1.15e-95

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 287.10  E-value: 1.15e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   1 MNNNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  81 eylMSWESEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQlSNFIFTIVILSIII 160
Cdd:MTH00160  81 ---NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 161 GAMGGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 241 FLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFSALILSYTENSWSMNAKNKSFKFTLP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*....
gi 383215307 321 ITVMVSTTGLMLTSTLIFM 339
Cdd:MTH00160 317 FLSFISLFGLILSSLLFLL 335
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 1.15e-95

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 287.10  E-value: 1.15e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   1 MNNNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  81 eylMSWESEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQlSNFIFTIVILSIII 160
Cdd:MTH00160  81 ---NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 161 GAMGGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 241 FLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFSALILSYTENSWSMNAKNKSFKFTLP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*....
gi 383215307 321 ITVMVSTTGLMLTSTLIFM 339
Cdd:MTH00160 317 FLSFISLFGLILSSLLFLL 335
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 3.58e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 105.47  E-value: 3.58e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   24 SNSWFGVWMGLEINLLSFIPMLTNNKNSMI-NESSIKYFIVQAMASTMLLFSILLI--------------QMEYLMSWES 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRsSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   89 EMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVL-MTWQKIAPMMIL-------SYCIQLSNFIFTIVILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  161 GAMGGLNQTSLRHLLAYSSISHLGWMISSMISSENI----WEIYFVIYSTLSLILVLLF-----KQMNLFLLNQIYTASN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYgiqaAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 383215307  232 MKTEIKFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 1.80e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 1.80e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   8 LLFLSTLmmGTILSISSNSWFGVWMGLEINLLSF---IPMLTNNKNSmiNESSIKYFIVQAMASTMLLF----------S 74
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLyvlVAFRRDDRRS--SEAALKYFLLGALSSGFLLYgisllygatgS 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  75 ILLIQMEYLMSWESEMVPSMLISSSLLL-----KIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMIL--------- 140
Cdd:COG1007  183 LNLAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafp 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 141 SYCIQLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMISSMIS-SENIWE---IYFVIYSTlslilvllfk 216
Cdd:COG1007  263 GLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLF---------- 332

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 217 qMNL---FLLNQIYTASNMKTEIK-------------FMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVM 280
Cdd:COG1007  333 -MNLgafAVILLLSRKGGEAEEIEdlaglarrspllaLAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVL 411

                        330
                 ....*....|..
gi 383215307 281 LTMITLYYYLRI 292
Cdd:COG1007  412 NSVISAYYYLRV 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-337 5.91e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 87.31  E-value: 5.91e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307    8 LLFLSTLmmGTILSISSNSWFGVWMGLEI-NLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIqmeYLMSW 86
Cdd:TIGR01770 107 LLLFALL--GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLI---YGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   87 ESEMVPSMLISSSLLL------------------KIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIA---PMMILSYCIQ 145
Cdd:TIGR01770 182 SLNFEDLLLFLSNGMLnisllllgivlilvgllfKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYIL 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  146 ------LSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGW-MISSMISSENIWE---IYFVIYSTLSLILVLLF 215
Cdd:TIGR01770 262 fgfseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKavlFYIFIYALMSLGAFGVL 341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  216 KQMNLFLLNQIYTASNMKTEIK------FMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYY 289
Cdd:TIGR01770 342 SLLRSYKDEWIEYISDFAGLFKtnpilaILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYY 421

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 383215307  290 LRIsfSALILSYTENSWSMNAK-NKSFKFTLPITVMVSTTGLMLTSTLI 337
Cdd:TIGR01770 422 LRV--VKVMYFDKPERRIPSNPqSKAQSLLLSISALFILFLGLFPSLIL 468
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 1.15e-95

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 287.10  E-value: 1.15e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   1 MNNNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  81 eylMSWESEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQlSNFIFTIVILSIII 160
Cdd:MTH00160  81 ---NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 161 GAMGGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 241 FLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFSALILSYTENSWSMNAKNKSFKFTLP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*....
gi 383215307 321 ITVMVSTTGLMLTSTLIFM 339
Cdd:MTH00160 317 FLSFISLFGLILSSLLFLL 335
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 6-340 2.76e-63

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 204.67  E-value: 2.76e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   6 TKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSIlLIQMEYLMS 85
Cdd:MTH00112   5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSS-TTNAWNTGQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  86 WE----SEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQLSNF--IFTIVILSII 159
Cdd:MTH00112  84 WDitqlTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPtlLLTLAILSTL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 160 IGAMGGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFM 239
Cdd:MTH00112 164 IGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTT 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 240 MFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISF-SALILSYTENSWSMN-AKNKSFKF 317
Cdd:MTH00112 244 LMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYiSTITLPPNTTNMMMKwRTKPKKNT 323

                        330       340
                 ....*....|....*....|...
gi 383215307 318 TLPITVMVSTTGLMLTSTLIFML 340
Cdd:MTH00112 324 LTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 3-340 5.60e-62

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 201.31  E-value: 5.60e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   3 NNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILlIQMEY 82
Cdd:MTH00041   2 NRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGAL-IQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  83 LMSW----ESEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQL--SNFIFTIVIL 156
Cdd:MTH00041  81 SGSWsingPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLlnSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 157 SIIIGAMGGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEI 236
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 237 KFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFSALILSYTENS-----WSMNAK 311
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSislfsWRNSGN 320

                        330       340
                 ....*....|....*....|....*....
gi 383215307 312 NKSFKFTLPITVMVSTTGLMLTSTLIFML 340
Cdd:MTH00041 321 ITVYGVILSILSSISILGLLLIPLFLSFL 349
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-339 1.07e-59

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 195.45  E-value: 1.07e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   8 LLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIQM---EYLM 84
Cdd:MTH00105   7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMysgQWTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  85 SWESEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILsYCIQLS---NFIFTIVILSIIIG 161
Cdd:MTH00105  87 TKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSIL-YQISPSinpNLLLTLAILSILIG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 162 AMGGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMMF 241
Cdd:MTH00105 166 GWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLIL 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 242 LSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFS-ALILSYTENSWSMNAKNKSFK--FT 318
Cdd:MTH00105 246 LTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYStSLTMFPSTNNMKMKWQFENTKpmTL 325

                        330       340
                 ....*....|....*....|.
gi 383215307 319 LPITVMVSTTGLMLTSTLIFM 339
Cdd:MTH00105 326 LPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-340 1.80e-58

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 192.06  E-value: 1.80e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  10 FLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILL---IQMEYLMSW 86
Cdd:MTH00070   9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInawFTGEWTIMN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  87 ESEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQL--SNFIFTIVILSIIIGAMG 164
Cdd:MTH00070  89 MQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLlnSNLLIIMGLLSTLIGGWG 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 165 GLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTaSNMKTEIKF-MMFLS 243
Cdd:MTH00070 169 GLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSS-SWSKNPTLTsMMMLT 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 244 LLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFS-ALILS-YTENSWSMNAKNKSFKFTLPI 321
Cdd:MTH00070 248 LLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAmSLTTSpNTSNSKLYWRFKNKTNNLLSL 327

                        330
                 ....*....|....*....
gi 383215307 322 TVMVSTTGLMLTSTLIFML 340
Cdd:MTH00070 328 TIILSLMLLPITPTILNLF 346
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-340 9.68e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 179.78  E-value: 9.68e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   6 TKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIQMEYLMS 85
Cdd:MTH00200   5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  86 WESEMV---PSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILS--YCIQLSNFIFTIVILSIII 160
Cdd:MTH00200  85 GISEMLgplSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 161 GAMGGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMM 240
Cdd:MTH00200 165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 241 FLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISF-SALILSYTENSWSMNAKNKSFKFTL 319
Cdd:MTH00200 245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYlTLLTLSPNQINMMSSWRTKSNSNLL 324

                        330       340
                 ....*....|....*....|..
gi 383215307 320 -PITVMVSTTGLMLTSTLIFML 340
Cdd:MTH00200 325 vGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-308 2.12e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 178.33  E-value: 2.12e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   9 LFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIQMEYLMSWES 88
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLSLLS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  89 emvpSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQLSNFIFTIVILSIIIGAMGGLNQ 168
Cdd:MTH00197  82 ----VVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 169 TSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMMFLSLLSIG 248
Cdd:MTH00197 158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 249 GLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFSALILSYTENSWSM 308
Cdd:MTH00197 238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLM 297
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 7-338 2.56e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 178.16  E-value: 2.56e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   7 KLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSIlLIQMEYLMSW 86
Cdd:MTH00144   6 NLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGS-LIMYNLSFSW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  87 ESEMVpsmlISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQLSNFIFTIVILSI---IIGAM 163
Cdd:MTH00144  85 FSMSL----LLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVlsaLVGSI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 164 GGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMMFLs 243
Cdd:MTH00144 161 GGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISL- 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 244 LLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFSALIlsytenSWSMNAKNKSFKFTLPITV 323
Cdd:MTH00144 240 LLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL------SSSKSKKSNSSKVLNSSII 313

                        330
                 ....*....|....*
gi 383215307 324 MVSTTGLMLTSTLIF 338
Cdd:MTH00144 314 SLNLLGGLLFLLLYL 328
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-332 3.46e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 178.46  E-value: 3.46e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   9 LFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILL---IQMEYLMS 85
Cdd:MTH00135   8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTnawLTGQWDIQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  86 WESEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMmILSYCIQLSN--FIFTIVILSIIIGAM 163
Cdd:MTH00135  88 QMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAPTNptLLITLGLTSTLVGGW 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 164 GGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMMFLS 243
Cdd:MTH00135 167 GGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLI 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 244 LLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFS-ALILSYTENSWSMNAKNKSFKFTLPIT 322
Cdd:MTH00135 247 LLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAmTLTISPNTLNGTTPWRLPSTQLTLPLA 326

                        330
                 ....*....|
gi 383215307 323 VMVSTTGLML 332
Cdd:MTH00135 327 ISTTATLMLL 336
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-302 3.85e-49

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 167.65  E-value: 3.85e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   6 TKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIQMEYLMS 85
Cdd:MTH00011   7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  86 wesEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYC--IQLSNFIFTIVILSIIIGAM 163
Cdd:MTH00011  87 ---KNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSALAGGL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 164 GGLNQTSLRHLLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMMFLS 243
Cdd:MTH00011 164 GGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIM 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 383215307 244 LLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRISFSALILSYT 302
Cdd:MTH00011 244 LLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPT 302
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 3.58e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 105.47  E-value: 3.58e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   24 SNSWFGVWMGLEINLLSFIPMLTNNKNSMI-NESSIKYFIVQAMASTMLLFSILLI--------------QMEYLMSWES 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRsSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   89 EMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVL-MTWQKIAPMMIL-------SYCIQLSNFIFTIVILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  161 GAMGGLNQTSLRHLLAYSSISHLGWMISSMISSENI----WEIYFVIYSTLSLILVLLF-----KQMNLFLLNQIYTASN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYgiqaAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 383215307  232 MKTEIKFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 1.80e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 1.80e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   8 LLFLSTLmmGTILSISSNSWFGVWMGLEINLLSF---IPMLTNNKNSmiNESSIKYFIVQAMASTMLLF----------S 74
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLyvlVAFRRDDRRS--SEAALKYFLLGALSSGFLLYgisllygatgS 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  75 ILLIQMEYLMSWESEMVPSMLISSSLLL-----KIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMIL--------- 140
Cdd:COG1007  183 LNLAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafp 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 141 SYCIQLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMISSMIS-SENIWE---IYFVIYSTlslilvllfk 216
Cdd:COG1007  263 GLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLF---------- 332

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 217 qMNL---FLLNQIYTASNMKTEIK-------------FMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVM 280
Cdd:COG1007  333 -MNLgafAVILLLSRKGGEAEEIEdlaglarrspllaLAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVL 411

                        330
                 ....*....|..
gi 383215307 281 LTMITLYYYLRI 292
Cdd:COG1007  412 NSVISAYYYLRV 423
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-292 3.91e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 101.26  E-value: 3.91e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  16 MGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMIN-ESSIKYFIVQAMASTMLLFSILLI--------------QM 80
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFGCALLcgttgglhlsyinlVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  81 EYLMSWESEMVPS--MLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQLSNFIFTIVILSI 158
Cdd:MTH00196  84 NSGQSFSSVSVPIgyLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 159 IIGAMGGLNQTSLRHLLAYSSISHLGWMISSM----ISSENIWEIYFVIY--STLSLILVLLFKQMNLFLLNQIYTASNM 232
Cdd:MTH00196 164 FVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYiiMSICVFSIILALNVYKNLIIEFSGLSRR 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 233 KTEIKFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRI 292
Cdd:MTH00196 244 LPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-292 7.40e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 98.55  E-value: 7.40e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  16 MGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMIN-ESSIKYFIVQAMASTMLLFSILLI-------QMEYLMSWE 87
Cdd:MTH00199 108 LGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAYStEAGLKYFVLGAVSSGLFLFGCALLygltgetSIQGINSIL 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  88 SEMVPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQLSNFIFTIVILSIIIGAMGGLN 167
Cdd:MTH00199 188 TGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAIGALN 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 168 QTSLRHLLAYSSISHLGWMISSM----ISSENIWEIYFVIYSTLSLILVLLFKQMNLF--LLNQIYTASNMKTEIKFMMF 241
Cdd:MTH00199 268 QTKIKRLLAYSGIGHMGFILFGVaigsFESIQASLIYMIIYVIMSICSFSIILSLKLTkgLIVEVSGLSRKNPVIALTLA 347

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 383215307 242 LSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRI 292
Cdd:MTH00199 348 LTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-292 1.93e-21

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 94.89  E-value: 1.93e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   8 LLFLSTLmmGTILSISSNSWFGVWMGLEI-NLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIqmeYLMSW 86
Cdd:PRK05777 108 LVLFALL--GMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLL---YGATG 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  87 ESEMVPSMLISSSLLL------------------KIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMIL-------- 140
Cdd:PRK05777 183 SLSFAGIAKALADGSGnsllllfglvfllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvaf 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 141 -SYCIQLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWM-----ISSMISSENIWeIYFVIYSTLSL----I 210
Cdd:PRK05777 263 gGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvglaAGTAEGYSAVL-FYLLAYLFMTLgafgV 341

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 211 LVLLFKQM----NLFLLNQIYTASNMKTeikFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITL 286
Cdd:PRK05777 342 ISLLRRKGgeaeSISDFAGLSKRSPLLA---AVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGA 418


                 ....*.
gi 383215307 287 YYYLRI 292
Cdd:PRK05777 419 FYYLRV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-337 5.91e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 87.31  E-value: 5.91e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307    8 LLFLSTLmmGTILSISSNSWFGVWMGLEI-NLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIqmeYLMSW 86
Cdd:TIGR01770 107 LLLFALL--GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLI---YGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   87 ESEMVPSMLISSSLLL------------------KIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIA---PMMILSYCIQ 145
Cdd:TIGR01770 182 SLNFEDLLLFLSNGMLnisllllgivlilvgllfKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYIL 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  146 ------LSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGW-MISSMISSENIWE---IYFVIYSTLSLILVLLF 215
Cdd:TIGR01770 262 fgfseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKavlFYIFIYALMSLGAFGVL 341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  216 KQMNLFLLNQIYTASNMKTEIK------FMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYY 289
Cdd:TIGR01770 342 SLLRSYKDEWIEYISDFAGLFKtnpilaILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYY 421

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 383215307  290 LRIsfSALILSYTENSWSMNAK-NKSFKFTLPITVMVSTTGLMLTSTLI 337
Cdd:TIGR01770 422 LRV--VKVMYFDKPERRIPSNPqSKAQSLLLSISALFILFLGLFPSLIL 468
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-292 8.20e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 77.88  E-value: 8.20e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  10 FLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLIQ-------MEY 82
Cdd:COG0651  112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYgatgtlnMAD 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  83 LMSWESEMVPSMLISSSLL------LKIGAAPFHFWFPEVMGA-----SEWFNCLVLmtwqKIAPMMIL---------SY 142
Cdd:COG0651  192 LAARLAELDPGLLLAAFALllvgfgIKAALFPLHFWLPDAYPAapspvSALLSGLLT----KVGVYAILrvltllfgaDP 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 143 CIQLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMISSM-ISSENIWE--IYFVIYSTLSLILvllfkqmn 219
Cdd:COG0651  268 ALFLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLgLGTPLGLAgaLFHLLNHALAKAL-------- 339

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 220 LFLLNQIYTASNMKTEIK-------------FMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITL 286
Cdd:COG0651  340 LFLAAGAIERATGTRDLDklgglgkrmpltaAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTL 419


                 ....*.
gi 383215307 287 YYYLRI 292
Cdd:COG0651  420 AYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-292 1.04e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 77.98  E-value: 1.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  16 MGTILSISSNSWFGVWMGLEINLLSFIPM---------LTNNKNSMINESSIKYFIVQAMASTMLLFSILL--------- 77
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFGCALyfgftgneg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  78 ----IQMEYLMSWESEM----VPSMLISSSLLLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQLSNF 149
Cdd:MTH00198 279 mlgtILSATLETTNIELrqgsLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 150 IFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMI-----SSMISSENIWeIYFVIYSTLSLILVLLFKQMNLFllN 224
Cdd:MTH00198 359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILigvsaGTYESLQASW-TYAVTYLVSALASFTVICTLEEF--G 435

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 225 QIYTASNMKTE-----------------------IKFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAI---- 277
Cdd:MTH00198 436 TRTPTSRQRDGsfgnynlvrrlvdltilsrgqpyIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSSLSIyylv 515

                        330
                 ....*....|....*...
gi 383215307 278 ---MVMLTMITLYYYLRI 292
Cdd:MTH00198 516 alfAIICTCISAFYYIRI 533
ndhB CHL00049
NADH dehydrogenase subunit 2
 103-328 2.71e-10

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 61.17  E-value: 2.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 103 KIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMM--------ILSYCIQLSNFIFTIV-ILSIIIGAMGGLNQTSLRH 173
Cdd:CHL00049 227 KLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASAlatrifdiPFYFSSNEWHLLLEILaILSMILGNLIAITQTSMKR 306

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 174 LLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLL--FKQMNLFLL----NQI--YTASNMKTEI-KFMMFLSL 244
Cdd:CHL00049 307 MLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYIFMNLgtFACIVLFGLrtgtDNIrdYAGLYTKDPFlALSLALCL 386

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 245 LSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRI------SFSALILSYTENS--WSMNAKNkSFK 316
Cdd:CHL00049 387 LSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKIikllmtGRNQEITPYVRNYrrSPLRSNN-SIE 465

                        250
                 ....*....|..
gi 383215307 317 FTLPITVMVSTT 328
Cdd:CHL00049 466 LSMIVCVIASTI 477
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
103-337 2.28e-09

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 58.52  E-value: 2.28e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 103 KIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIA----PMMILSYCIQLSN----FIFTIV-ILSIIIGAMGGLNQTSLRH 173
Cdd:PRK02504 223 KISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDeqwkLLFTALaILSMVLGNVVALAQTSMKR 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 174 LLAYSSISHLGW-MISSMISSENiweiyfvIYSTLSL-ILVLLFkqMNL-----FLLNQIYTASNMKTE----------I 236
Cdd:PRK02504 303 MLAYSSIGQAGFvMIGLVAGTEA-------GYASMVFyLLAYLF--MNLgafacVILFSLRTGTDQISDyaglyqkdplL 373

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 237 KFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRI----------SFSALILSYTENSW 306
Cdd:PRK02504 374 TLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRVikmmvvkepqEMSDVVKNYPEINW 453

                        250       260       270
                 ....*....|....*....|....*....|.
gi 383215307 307 SMNAKnKSFKFTLPITVMVSTTGLMLTSTLI 337
Cdd:PRK02504 454 NLPGM-RPLRVGLVLCVIATALAGILSNPLF 483
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-296 1.48e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 55.87  E-value: 1.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  55 ESSIKYFIVQAMASTMLLFSILLI-------QMEYLMSWESE------MVPSMLISSSLLLKIGAAPFHFWFPEVMGA-- 119
Cdd:PRK08376 172 EAGIKYMFVGSLASSMVLLGIALLygqygtlNMAYLAVKMSEnptvvaKIALALFIAGLAMKSGAVPVHMWLPDAYPAap 251

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 120 SEWFNCLVLMTWQKIAPMMILSYCI--------QLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMI---- 187
Cdd:PRK08376 252 SSISAMLLVIKQAGLYALARVLFSIygpainlaTVGWVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLlglg 331

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 188 ------SSMISSE--------NIWEI--YFVIYSTLSLILVLLFKQMNLFLLNQIY-TASNM-KTEIKFMmfLSLLSIGG 249
Cdd:PRK08376 332 vglaalGDPAMASygeialagGIYHIvnHALYKALLFLTAGAVIYETGTRNLNELGgLARTMpKTTIAFL--IGAAAIVG 409

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 383215307 250 LPPFIGFLPKWMVMQSMMEMNmTSLMAIMVMLTMITLYYYLRISFSA 296
Cdd:PRK08376 410 LPPFNGFASKWLIYESSALFN-PILGVIAMIGSVLTLASFVKVFHTA 455
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 146-292 2.41e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 55.27  E-value: 2.41e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 146 LSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMIssmisseniweIYFVIYSTLSLI--LVLLFKQM----N 219
Cdd:PRK08375 270 LGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYIL-----------LGLALLTPLALAagLLHLLHHAlmkgA 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 220 LFL-LNQIYTASNMKT---------EIKFMM---FLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITL 286
Cdd:PRK08375 339 LFLaAGAIEVTYGTRRlselsglgrRMPLTAaafAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLAL 418


                 ....*.
gi 383215307 287 YYYLRI 292
Cdd:PRK08375 419 LYFLRI 424
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
146-296 8.39e-08

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 53.42  E-value: 8.39e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 146 LSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMISSmISSENIWEIYFVIYSTLSLILVLLFkqmnLFLLNQ 225
Cdd:PRK12663 271 LHPLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILLG-LALGTPAGINGAIFYLVHDMVVKTA----LFLIAG 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 226 IYTASNMKTEIKFM-------------MFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLRI 292
Cdd:PRK12663 346 SLVRLTGYRSLQYLgglyrkeplfgalFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRI 425


                 ....
gi 383215307 293 SFSA 296
Cdd:PRK12663 426 FFLA 429
PRK12650 PRK12650
DUF4040 family protein;
108-298 9.65e-07

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 50.43  E-value: 9.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 108 PFHFWFPEVMGA----SEWFNCLVLMtwqKIAPMMILSYCIQLSN------FIFTIVILSIIIGAMGGLNQTSLRHLLAY 177
Cdd:PRK12650 226 PFHFWLPEAMAAitpvSAFLHAAAVV---KAGIYLLLRFSPVFHDvavwnwLLIIVGMITALMGAVFAVQKTDLKKLTAY 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 178 SSISHLGWmISSMISSENIWEIYFVIYSTLSLIlvlLFKQmNLFLL-----NQIYT-------ASNMKTEIKF-MMFLSL 244
Cdd:PRK12650 303 STVSQLGW-IVATIGVGTPFALTAAVVHTLAHA---LFKS-SLFMLigvvdHQAGTrdirrlgSLWRRMPFTFvSVTIAA 377

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 383215307 245 LSIGGLPPFIGFLPKWMVMQSMME-----MNMTSLMAIMVMLTMITLYYYLRISFSALI 298
Cdd:PRK12650 378 LSMAAVPPLFGFVSKEGMLTAFLEapggnAGVVLLLVGAALGAVFTFAYSARLVLGAFV 436
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 145-292 1.79e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 49.58  E-value: 1.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 145 QLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMISSMISSENI---WEIYFVIY-----STLSLILVLLFK 216
Cdd:PRK12665 271 GLDTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAglsGAIYYVAHhitvqTTLFLVVGLIER 350

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 383215307 217 QMNLFLLNQIYTASNMKTEIKFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMT---SLMAIMVMLTMITLYYYLRI 292
Cdd:PRK12665 351 QAGSSSLRRLGGLAKASPLLAVLFFVPALNLGGIPPFSGFIGKVALLEAGAEDGTWlawALVAGGVVTSLLTLYAVARV 429
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
53-295 2.14e-06

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 49.26  E-value: 2.14e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  53 INESSIKYFIVQAMASTMLLFSILLIQMEYLMSwesemvpsmlissslllkIGAAPFHFWFPEVMGASEWFNCLVLMTWQ 132
Cdd:PRK06277 180 LNITDIHNALLVNPTSPVIYGGLLLLIFGLLYG------------------SGLPPFHTIKSDIYAKAKPFGSALLQTFS 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 133 K---IAPMMI-------LSYCIQLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMISSM-------ISSEN 195
Cdd:PRK06277 242 KfvlVALMLVifklfggLSYFPSAQGVLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLalgtplgIVAGI 321

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 196 IWEIYFVIY-STLSLILVLLFKQMNLFLLNQIYTASNMKTEIKFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSL 274
Cdd:PRK06277 322 FHAINHVIYkSALFLGAGIVSYRTKTSNLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQAAMQANMPEL 401

                        250       260
                 ....*....|....*....|.
gi 383215307 275 MAIMVMLTMITLYYYLRISFS 295
Cdd:PRK06277 402 AIIMIIVSIGTFVSMMKAFYL 422
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 146-295 2.93e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 48.81  E-value: 2.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 146 LSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGW--MISSMISSeniweiyFVIYSTLSLILVLLFKQMNLFLL 223
Cdd:PRK12667 294 LSPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYifMGIGIGTQ-------LGLAAALFHIINHAIAKSLLFLA 366

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 224 NQIYTASNMKTEIK-------------FMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYL 290
Cdd:PRK12667 367 SGVFIHAAGTRDIDelaglgrkmpiasFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYF 446


                 ....*
gi 383215307 291 RISFS 295
Cdd:PRK12667 447 RAWYS 451
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 3-305 4.34e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 45.19  E-value: 4.34e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   3 NNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLI---- 78
Cdd:PRK06589 114 SSSRFLFFFNLTILIGVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPAVILiytk 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  79 --QMEYLMSWESEMVPSMLISSSLLLKIGAA---PFHFWFPEVMGASEWFNCLV---------LMTWQKIAPMM----IL 140
Cdd:PRK06589 194 tgNLDFVSGGLFSKNQSIILLLMFIYGIAKTaifPVHSWLPAAMVAHYPVSALLhavivvktgLFCIYKILLYIfglsYL 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 141 SYCIQLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMI-SSMISSENIWEIYFVIYSTLSLILVLLFKQMN 219
Cdd:PRK06589 274 QRIFAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALlSAFILTPKALGAAILHLVSHSFAKICLFYSMG 353

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 220 LFL-------LNQIYTASNMKTEIKFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSL----MAIMVMLTMITLYY 288
Cdd:PRK06589 354 SIYslkkedqVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLsiivMLVVIASSILSALY 433

                        330
                 ....*....|....*..
gi 383215307 289 YLRISFSALILSYTENS 305
Cdd:PRK06589 434 LLKILSSIYKPSLSENS 450
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 14-325 1.23e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 42.94  E-value: 1.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  14 LMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINessikYFIVQAMASTMLLFSILLIQMEYLMswesemvps 93
Cdd:MTH00091   3 LSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLFNY-----FVLQESLGLLFLLFSFGYFQFLILM--------- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  94 mlisssllLKIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQLSNFIFTIVILSIIIGAMggLNQTSLRH 173
Cdd:MTH00091  69 --------MKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQM--FLLKSYKN 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 174 LLAYSSISHLGWMISSMISSENIWEIYFVIYSTLSLILVLLFkqmnlfllnqiytasNMKTEIKFMMFLSLLSIGGLPPF 253
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKF---------------NNVNKLNFVSWETLLVFMNLPFS 203

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 383215307 254 IGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYyylrISFSALILSYTENSWSMNAKNKSFKFTLPITVMV 325
Cdd:MTH00091 204 VTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLS----LSFWLVNLSTKLFLMLFKYNKGFFFFFLPLMLLS 271
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 1-292 2.45e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 42.68  E-value: 2.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   1 MNNNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLL-SFIPMLTNNKNSmiNESSIKYFIVQAMASTMLLFSILLI- 78
Cdd:PRK08668  94 TKNDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFsSFMMVPMGKKES--RKASLKYFVLSAIGAYAMLYAIFLIy 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  79 -------------QMEYLMSWESEMVPSMLISSSLLLKIGAAPFHFWFPEV------------------MGASEWFNCLV 127
Cdd:PRK08668 172 aktgtfdfadisqGLINDTSTGFALIVFLFLLAFGVAKAGIFPLHVWAPDAyseapqsfsavlsgqlskLGAYGFLLVLY 251

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 128 LMTWQKIAPMMILSYCIQLSNFIF-TIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWM---ISSMISSENIWEIYFVI 203
Cdd:PRK08668 252 VLPGTKLFSEFGTYRGVPLFNYILaWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYIlvgLGLGTSLGFAGGLFHVF 331

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 204 YSTlslilvlLFKQMnLFLLNQIYTASNMKTEIK-------------FMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMN 270
Cdd:PRK08668 332 NHA-------LFKGL-FFLIFAAVIYRTGTTKISemggliekmpftfAMYLVAIISLAGIPPMSGFASKWLIFEALISKG 403

                        330       340
                 ....*....|....*....|..
gi 383215307 271 MTSLMAIMVMLTMITLYYYLRI 292
Cdd:PRK08668 404 MPITAFMAFFGSIGSFLYVFRP 425
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 103-263 3.79e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 42.25  E-value: 3.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 103 KIGAAPFHFWFPEVMGASEWFNCLVLMTWQKIAPMMILSYCIQLSNFIFTIV----ILSIIIGAMGGLNQTSLRHLLAYS 178
Cdd:PRK07234 197 KGGIFVSGLWLPLTHSEAEPPVSALLSGVVVKAGVFPLVRCALDVPGLDLIVrifgVGTALLGVLFALLEKDLKRMLAFS 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 179 SISHLGWMISSMISSEniweiyfvIYStLSLILVLLFkqmnLFLLNQIYTASNMKTEIKFM------MFLSL--LSIGGL 250
Cdd:PRK07234 277 TISQLGFILAAPLVGG--------LYA-LAHGLVKST----LFLCAGALPSRNFTELISQMlgigkwIPLTMasFSIAGF 343

                        170
                 ....*....|...
gi 383215307 251 PPFIGFLPKWMVM 263
Cdd:PRK07234 344 PLLAGFVSKVLTL 356
PRK12646 PRK12646
DUF4040 family protein;
108-325 1.46e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 40.51  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 108 PFHFWFPEVMGASEWFNCLV---LMTWQKIAPMMILSYCIQLSNFIFTIV----ILSIIIGAMGGLNQTSLRHLLAYSSI 180
Cdd:PRK12646 228 PFHIWLPRAMAAPTPVSAYLhsaTMVKAGIFLLFRFTPLLGLSNMYIYIVtfvgLITMLFGSITALKQWDLKGILAYSTI 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 181 SHLGwMISSMI---------SSENIWEIYFVIystlslILVLLFKQMN-------LFL----------LNQIYTASNMKT 234
Cdd:PRK12646 308 SQLG-MIMAMVgigggyaqhQQDAIASIYVFV------LFAALFHLMNhaifkcaLFMgvgiidheagTRDIRILSGMRQ 380

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 235 EIKFM---MFLSLLSIGGLPPFIGFLPKWMVMQSMMEMN---------MTSLMAIMVMLTMITLYYYLRISFSALILSYT 302
Cdd:PRK12646 381 LFPKMnlvMTIAALSMAGVPFLNGFLSKEMFLDALTQTGqlsqfslisMIIIVFIGVIASIFTFTYALYMVKEVFWGKYD 460

                        250       260
                 ....*....|....*....|...
gi 383215307 303 ENSWSMNAKNKSFKFTLPITVMV 325
Cdd:PRK12646 461 SKVFTKKNIHEPWLFSLPSLILM 483
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 108-187 3.16e-03

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 39.15  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  108 PFHFWFPEVMGASEWFNCLVLM-TWQKIAPMMILSYCIQL--------SNFIFTIVILSIIIGAMGGLNQTSLRHLLAYS 178
Cdd:TIGR01972 221 PLHTWLPDAHVEAPTAGSVILAgVLLKMGTYGFLRFNLPLfpdaslyfAPVLAALGVIAIIYGALIALAQTDIKRLIAYS 300


                  ....*....
gi 383215307  179 SISHLGWMI 187
Cdd:TIGR01972 301 SISHMGFVL 309
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 145-184 3.21e-03

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 39.29  E-value: 3.21e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 383215307 145 QLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLG 184
Cdd:COG1008  273 YFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMG 312
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 8-292 4.09e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 38.98  E-value: 4.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307   8 LLFLsTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLTNNKNSMINESSIKYFIVQAMASTMLLFSILLI-------QM 80
Cdd:PRK08377 112 MLFL-LLMLGATGMIATGDIFNLFVFMEITAITAYALTAYNKTGEAAEASMKYIVLGGIGSSFFLIGVALIygatgtlNM 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307  81 EYLMSWESEMVPSMLISSSLLLKIGAA------PFHFWFPEVMGA-----SEWFNCLVLMTwqKIAPMMILSYCIQLSN- 148
Cdd:PRK08377 191 AHIAQLAGTIDPTVAQVGLALLIFGLAveaelfPLNAWAPDAYQAaphpiTVMFSAFVVKA--GLYAMARILYLMQNANg 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 149 ------FIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMISSM-ISSENIWEIYFVIYSTLSLILVLLFKQMNLF 221
Cdd:PRK08377 269 wssvlkLVIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALaLGTQAGVDAGVFHMINHAIVKALLFLAVGYV 348

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 222 llnqIYTASNMKTE-----------IKFMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYL 290
Cdd:PRK08377 349 ----GITLGGTEIEkfeglgkrmplTALALTIGALSTVGIPLFNVFWSKFRIILAGLSAGYTWPVALVLGASVVEAVYYF 424


                 ..
gi 383215307 291 RI 292
Cdd:PRK08377 425 RL 426
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 148-292 5.10e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 38.39  E-value: 5.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 148 NFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWM---ISSMISSENIWEIYFVIYStlslilvLLFKQMnLFLLN 224
Cdd:PRK07691 276 YLILILALLTIIFGVIGAVAYFDIKKIIIYNIMIAVGVIlvgVAMMTESGMIGAIYYLIHD-------MIVKAA-LFLLI 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383215307 225 QIYTASNMKTEIK-------------FMMFLSLLSIGGLPPFIGFLPKWMVMQSMMEMNMTSLMAIMVMLTMITLYYYLR 291
Cdd:PRK07691 348 GIMIKITGTTDLKkmgglikrypvlgWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLVLYSVIK 427


                 .
gi 383215307 292 I 292
Cdd:PRK07691 428 I 428
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 145-187 7.94e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 37.87  E-value: 7.94e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 383215307 145 QLSNFIFTIVILSIIIGAMGGLNQTSLRHLLAYSSISHLGWMI 187
Cdd:PRK05846 275 EFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVT 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH