NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|383513818|gb|AFH41499|]
View 

VP1 [Tilligerry virus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Orbi_VP1 super family cl12314
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 3-1302 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


The actual alignment was detected with superfamily member pfam05788:

Pssm-ID: 461740  Cd Length: 1297  Bit Score: 1297.37  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818     3 ATVRGVDIVDRVLKRFYPTAEFDYTRGFWHLYRFSSNIRIIRRKKGTKYRRDDDVLTNLVDRRSETLYGIRVLNEASWEE 82
Cdd:pfam05788    4 ITVQGAQLIKRVVERFYPGIAFAINEGACYIYKFSDHIRRIRMKHGTKYRRQAEEILRKISLRKERLYGIPVLDEVEWKY 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818    83 LTEEYSRRSKGLGIFENSVLDHEELDPEEEFLRNYRViEDGAGHLSTFIETRAKVEMQVYGDLPMKIWFIFVEQLCKHVG 162
Cdd:pfam05788   84 VFDGQTFQSYAFEVYVNSILPWSELDPEEEFLRNYRV-SREKTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIELG 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   163 FETEGLTVMKSFlfkygAPFHQGLRDLSKLDGFKMSYSTPMLFEMSCMESLLEINIFKRMQEERIHCLQFGDREINPIAL 242
Cdd:pfam05788  163 MQPLGMQVMADF-----VNRFQSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEEISALEFGDVKL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   243 LREFYLICLPHPKRINNILRSPYSWFVKTWGVAANPIVVLRSSGGDDRNSKDIYYEKFHYVENTYVPIFNARFYRKSLED 322
Cdd:pfam05788  238 DPVGLLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRYKALFRSSFYN 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   323 NMNKVNEAIEYSQGLGQHEEGLPIFTSMLEEVYKTPFVPNKPSNLILASFLLSIQTITGYGRAWVKNVGTDFGKQMKPSK 402
Cdd:pfam05788  318 ESRRMNEEKILEAVKYSQDLGSHDRRLPLFEKMLKPVYTTPFYPHKSSNMILASFLLSIQTITGYGRAWVKNVSTEFDKQ 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   403 DNFIERVADYTANNFIAAYEEARQHHEDIVFPEDLYTSMLRLARNTSSGFSTSVKVRKAFGPNvKRKPELIDVTSRIKAL 482
Cdd:pfam05788  398 LKPNPSNLVLDVSDLTREFFKQAYVEAKERREEDVKPEDLYTSMLRLARNTSSGFSTEIYVKK-RFGPRLRDKDLRKINS 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   483 VIFTKGHTVFTPEELNKKYDTATNYQTKGSREVPIKATRTIYSINLSVLVPQLVVTLPLNEYFARVGGSTSPNCKRMGGK 562
Cdd:pfam05788  477 RIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITKPDYK 556

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   563 IIVGDLEATGSRVMDAADTFRNSADPSTFTLAIDYSEYDTHLTRYNFRNGMMRGLRAAMLKYRDLRYEGYSLDDLIDFGY 642
Cdd:pfam05788  557 KIGGKVIVGDLEATGSRVMDAADCFRNSADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRGLRYEGYTLEQI 636

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   643 GDGRVAMTLWNGKRRVFKVPAHLYIMLDEEERRQGDFRPPPGVRPVTSMNVAEKLVRGKTVSDdfiLISPTDGSDLALID 722
Cdd:pfam05788  637 IDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDKGSFKVPKGVLPVSSVDVANRIAVD---KGFDTLIAATDGSD 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   723 THLSGENSTLIANSMHNMAIGTIIQEEVLKRYPTEISFQSEQYVGDDTLLYTQLLTRDPRVVNDIIETTFSSVEKCGHEA 802
Cdd:pfam05788  714 LALIDTHLSGENSTLIANSMHNMAIGTLGQRQVGREQPGSLTFLSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAK 793

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   803 SASKTMVYPFSVEKTQTHAKQGIYVPQDRMMIISSERRKDIENVNGYMRSQVHTMVTKVSRGFSHDLAQWILMLKTVFVG 882
Cdd:pfam05788  794 CGHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLK 873

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   883 AWKLKRTIKDTHGYRDRKFDDDTEDGFTLVTLKNPLALHIPQNWGGYGAHPAALNIVMTEEMFIDSMQISKLETEMQLLV 962
Cdd:pfam05788  874 TTFIGAWKMKRTIKEDAMYRDRKFDSNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEI 953

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   963 KIAGKLPPAWDETQADKRQISAETKMSFFSKMARPAVRATLMVPEIMDVVETLPLGDFGPGRLSKTMMHSALLKEANARS 1042
Cdd:pfam05788  954 MAPIRRIVHDIPPCWNETQGDKRGLISATKKSFFSKMARPAVQAALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKE 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818  1043 LLVSSYELEYQKQLNGWKEQP----MCFTLDEESGYVSSKYAKMFDIHFDEEIMEPAHVFPDQNLSPQFYVQKAIIGQRK 1118
Cdd:pfam05788 1034 SSASGLLSSGYKLEYQKALNVwirqVSMRLGEESGVISTSYAKLFDVYFEGELDGAPQMFPDQNLSPQFYIQKMMIGPRV 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818  1119 STRMRMSYIDRIDAILRKDVVMRGFLTANTIVNVLEKVGVSHTAVDLVTLFTLMNIEVKVAEELAEYITSERVRFDAIKL 1198
Cdd:pfam05788 1114 SSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLGTNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKL 1193

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818  1199 LKKGIVGDEFSMSLDVATQDMIDQLIRYPHELTKTELDAVSLYVSQLIMLRAALGMKKRRIRVSISPDERERFRAKVQRY 1278
Cdd:pfam05788 1194 LKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDAISLYCTQMAMLRAALGLPKKKMKIVVTDDAKKRYKIRLQRF 1273

                         1290      1300
                   ....*....|....*....|....
gi 383513818  1279 KTHTPKLKLIKKLIDINRLSVRAL 1302
Cdd:pfam05788 1274 RTHVPKIKVLKKLIDPNRMTVRNL 1297
 
Name Accession Description Interval E-value
Orbi_VP1 pfam05788
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 3-1302 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


Pssm-ID: 461740  Cd Length: 1297  Bit Score: 1297.37  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818     3 ATVRGVDIVDRVLKRFYPTAEFDYTRGFWHLYRFSSNIRIIRRKKGTKYRRDDDVLTNLVDRRSETLYGIRVLNEASWEE 82
Cdd:pfam05788    4 ITVQGAQLIKRVVERFYPGIAFAINEGACYIYKFSDHIRRIRMKHGTKYRRQAEEILRKISLRKERLYGIPVLDEVEWKY 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818    83 LTEEYSRRSKGLGIFENSVLDHEELDPEEEFLRNYRViEDGAGHLSTFIETRAKVEMQVYGDLPMKIWFIFVEQLCKHVG 162
Cdd:pfam05788   84 VFDGQTFQSYAFEVYVNSILPWSELDPEEEFLRNYRV-SREKTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIELG 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   163 FETEGLTVMKSFlfkygAPFHQGLRDLSKLDGFKMSYSTPMLFEMSCMESLLEINIFKRMQEERIHCLQFGDREINPIAL 242
Cdd:pfam05788  163 MQPLGMQVMADF-----VNRFQSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEEISALEFGDVKL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   243 LREFYLICLPHPKRINNILRSPYSWFVKTWGVAANPIVVLRSSGGDDRNSKDIYYEKFHYVENTYVPIFNARFYRKSLED 322
Cdd:pfam05788  238 DPVGLLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRYKALFRSSFYN 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   323 NMNKVNEAIEYSQGLGQHEEGLPIFTSMLEEVYKTPFVPNKPSNLILASFLLSIQTITGYGRAWVKNVGTDFGKQMKPSK 402
Cdd:pfam05788  318 ESRRMNEEKILEAVKYSQDLGSHDRRLPLFEKMLKPVYTTPFYPHKSSNMILASFLLSIQTITGYGRAWVKNVSTEFDKQ 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   403 DNFIERVADYTANNFIAAYEEARQHHEDIVFPEDLYTSMLRLARNTSSGFSTSVKVRKAFGPNvKRKPELIDVTSRIKAL 482
Cdd:pfam05788  398 LKPNPSNLVLDVSDLTREFFKQAYVEAKERREEDVKPEDLYTSMLRLARNTSSGFSTEIYVKK-RFGPRLRDKDLRKINS 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   483 VIFTKGHTVFTPEELNKKYDTATNYQTKGSREVPIKATRTIYSINLSVLVPQLVVTLPLNEYFARVGGSTSPNCKRMGGK 562
Cdd:pfam05788  477 RIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITKPDYK 556

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   563 IIVGDLEATGSRVMDAADTFRNSADPSTFTLAIDYSEYDTHLTRYNFRNGMMRGLRAAMLKYRDLRYEGYSLDDLIDFGY 642
Cdd:pfam05788  557 KIGGKVIVGDLEATGSRVMDAADCFRNSADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRGLRYEGYTLEQI 636

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   643 GDGRVAMTLWNGKRRVFKVPAHLYIMLDEEERRQGDFRPPPGVRPVTSMNVAEKLVRGKTVSDdfiLISPTDGSDLALID 722
Cdd:pfam05788  637 IDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDKGSFKVPKGVLPVSSVDVANRIAVD---KGFDTLIAATDGSD 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   723 THLSGENSTLIANSMHNMAIGTIIQEEVLKRYPTEISFQSEQYVGDDTLLYTQLLTRDPRVVNDIIETTFSSVEKCGHEA 802
Cdd:pfam05788  714 LALIDTHLSGENSTLIANSMHNMAIGTLGQRQVGREQPGSLTFLSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAK 793

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   803 SASKTMVYPFSVEKTQTHAKQGIYVPQDRMMIISSERRKDIENVNGYMRSQVHTMVTKVSRGFSHDLAQWILMLKTVFVG 882
Cdd:pfam05788  794 CGHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLK 873

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   883 AWKLKRTIKDTHGYRDRKFDDDTEDGFTLVTLKNPLALHIPQNWGGYGAHPAALNIVMTEEMFIDSMQISKLETEMQLLV 962
Cdd:pfam05788  874 TTFIGAWKMKRTIKEDAMYRDRKFDSNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEI 953

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   963 KIAGKLPPAWDETQADKRQISAETKMSFFSKMARPAVRATLMVPEIMDVVETLPLGDFGPGRLSKTMMHSALLKEANARS 1042
Cdd:pfam05788  954 MAPIRRIVHDIPPCWNETQGDKRGLISATKKSFFSKMARPAVQAALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKE 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818  1043 LLVSSYELEYQKQLNGWKEQP----MCFTLDEESGYVSSKYAKMFDIHFDEEIMEPAHVFPDQNLSPQFYVQKAIIGQRK 1118
Cdd:pfam05788 1034 SSASGLLSSGYKLEYQKALNVwirqVSMRLGEESGVISTSYAKLFDVYFEGELDGAPQMFPDQNLSPQFYIQKMMIGPRV 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818  1119 STRMRMSYIDRIDAILRKDVVMRGFLTANTIVNVLEKVGVSHTAVDLVTLFTLMNIEVKVAEELAEYITSERVRFDAIKL 1198
Cdd:pfam05788 1114 SSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLGTNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKL 1193

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818  1199 LKKGIVGDEFSMSLDVATQDMIDQLIRYPHELTKTELDAVSLYVSQLIMLRAALGMKKRRIRVSISPDERERFRAKVQRY 1278
Cdd:pfam05788 1194 LKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDAISLYCTQMAMLRAALGLPKKKMKIVVTDDAKKRYKIRLQRF 1273

                         1290      1300
                   ....*....|....*....|....
gi 383513818  1279 KTHTPKLKLIKKLIDINRLSVRAL 1302
Cdd:pfam05788 1274 RTHVPKIKVLKKLIDPNRMTVRNL 1297
 
Name Accession Description Interval E-value
Orbi_VP1 pfam05788
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 3-1302 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


Pssm-ID: 461740  Cd Length: 1297  Bit Score: 1297.37  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818     3 ATVRGVDIVDRVLKRFYPTAEFDYTRGFWHLYRFSSNIRIIRRKKGTKYRRDDDVLTNLVDRRSETLYGIRVLNEASWEE 82
Cdd:pfam05788    4 ITVQGAQLIKRVVERFYPGIAFAINEGACYIYKFSDHIRRIRMKHGTKYRRQAEEILRKISLRKERLYGIPVLDEVEWKY 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818    83 LTEEYSRRSKGLGIFENSVLDHEELDPEEEFLRNYRViEDGAGHLSTFIETRAKVEMQVYGDLPMKIWFIFVEQLCKHVG 162
Cdd:pfam05788   84 VFDGQTFQSYAFEVYVNSILPWSELDPEEEFLRNYRV-SREKTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIELG 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   163 FETEGLTVMKSFlfkygAPFHQGLRDLSKLDGFKMSYSTPMLFEMSCMESLLEINIFKRMQEERIHCLQFGDREINPIAL 242
Cdd:pfam05788  163 MQPLGMQVMADF-----VNRFQSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEEISALEFGDVKL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   243 LREFYLICLPHPKRINNILRSPYSWFVKTWGVAANPIVVLRSSGGDDRNSKDIYYEKFHYVENTYVPIFNARFYRKSLED 322
Cdd:pfam05788  238 DPVGLLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRYKALFRSSFYN 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   323 NMNKVNEAIEYSQGLGQHEEGLPIFTSMLEEVYKTPFVPNKPSNLILASFLLSIQTITGYGRAWVKNVGTDFGKQMKPSK 402
Cdd:pfam05788  318 ESRRMNEEKILEAVKYSQDLGSHDRRLPLFEKMLKPVYTTPFYPHKSSNMILASFLLSIQTITGYGRAWVKNVSTEFDKQ 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   403 DNFIERVADYTANNFIAAYEEARQHHEDIVFPEDLYTSMLRLARNTSSGFSTSVKVRKAFGPNvKRKPELIDVTSRIKAL 482
Cdd:pfam05788  398 LKPNPSNLVLDVSDLTREFFKQAYVEAKERREEDVKPEDLYTSMLRLARNTSSGFSTEIYVKK-RFGPRLRDKDLRKINS 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   483 VIFTKGHTVFTPEELNKKYDTATNYQTKGSREVPIKATRTIYSINLSVLVPQLVVTLPLNEYFARVGGSTSPNCKRMGGK 562
Cdd:pfam05788  477 RIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITKPDYK 556

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   563 IIVGDLEATGSRVMDAADTFRNSADPSTFTLAIDYSEYDTHLTRYNFRNGMMRGLRAAMLKYRDLRYEGYSLDDLIDFGY 642
Cdd:pfam05788  557 KIGGKVIVGDLEATGSRVMDAADCFRNSADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRGLRYEGYTLEQI 636

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   643 GDGRVAMTLWNGKRRVFKVPAHLYIMLDEEERRQGDFRPPPGVRPVTSMNVAEKLVRGKTVSDdfiLISPTDGSDLALID 722
Cdd:pfam05788  637 IDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDKGSFKVPKGVLPVSSVDVANRIAVD---KGFDTLIAATDGSD 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   723 THLSGENSTLIANSMHNMAIGTIIQEEVLKRYPTEISFQSEQYVGDDTLLYTQLLTRDPRVVNDIIETTFSSVEKCGHEA 802
Cdd:pfam05788  714 LALIDTHLSGENSTLIANSMHNMAIGTLGQRQVGREQPGSLTFLSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAK 793

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   803 SASKTMVYPFSVEKTQTHAKQGIYVPQDRMMIISSERRKDIENVNGYMRSQVHTMVTKVSRGFSHDLAQWILMLKTVFVG 882
Cdd:pfam05788  794 CGHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLK 873

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   883 AWKLKRTIKDTHGYRDRKFDDDTEDGFTLVTLKNPLALHIPQNWGGYGAHPAALNIVMTEEMFIDSMQISKLETEMQLLV 962
Cdd:pfam05788  874 TTFIGAWKMKRTIKEDAMYRDRKFDSNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEI 953

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818   963 KIAGKLPPAWDETQADKRQISAETKMSFFSKMARPAVRATLMVPEIMDVVETLPLGDFGPGRLSKTMMHSALLKEANARS 1042
Cdd:pfam05788  954 MAPIRRIVHDIPPCWNETQGDKRGLISATKKSFFSKMARPAVQAALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKE 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818  1043 LLVSSYELEYQKQLNGWKEQP----MCFTLDEESGYVSSKYAKMFDIHFDEEIMEPAHVFPDQNLSPQFYVQKAIIGQRK 1118
Cdd:pfam05788 1034 SSASGLLSSGYKLEYQKALNVwirqVSMRLGEESGVISTSYAKLFDVYFEGELDGAPQMFPDQNLSPQFYIQKMMIGPRV 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818  1119 STRMRMSYIDRIDAILRKDVVMRGFLTANTIVNVLEKVGVSHTAVDLVTLFTLMNIEVKVAEELAEYITSERVRFDAIKL 1198
Cdd:pfam05788 1114 SSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLGTNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKL 1193

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383513818  1199 LKKGIVGDEFSMSLDVATQDMIDQLIRYPHELTKTELDAVSLYVSQLIMLRAALGMKKRRIRVSISPDERERFRAKVQRY 1278
Cdd:pfam05788 1194 LKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDAISLYCTQMAMLRAALGLPKKKMKIVVTDDAKKRYKIRLQRF 1273

                         1290      1300
                   ....*....|....*....|....
gi 383513818  1279 KTHTPKLKLIKKLIDINRLSVRAL 1302
Cdd:pfam05788 1274 RTHVPKIKVLKKLIDPNRMTVRNL 1297
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH