NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|385281323|gb|AFI57819|]
View 

NADH dehydrogenase subunit 3, partial (mitochondrion) [Thylacinus cynocephalus]

Protein Classification

NADH dehydrogenase subunit 3( domain architecture ID 10009567)

NADH dehydrogenase subunit 3 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND3 MTH00106
NADH dehydrogenase subunit 3; Provisional
 1-91 1.68e-50

NADH dehydrogenase subunit 3; Provisional


:

Pssm-ID: 177168 [Multi-domain]  Cd Length: 115  Bit Score: 154.33  E-value: 1.68e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAMQ 80
Cdd:MTH00106   1 MNLMLTLLTNTLLASLLVLIAFWLPQLNIYSEKASPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWASQ 80

                         90
                 ....*....|.
gi 385281323  81 LTSTKTTLILS 91
Cdd:MTH00106  81 TNNLNTMLTMA 91
 
Name Accession Description Interval E-value
ND3 MTH00106
NADH dehydrogenase subunit 3; Provisional
 1-91 1.68e-50

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177168 [Multi-domain]  Cd Length: 115  Bit Score: 154.33  E-value: 1.68e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAMQ 80
Cdd:MTH00106   1 MNLMLTLLTNTLLASLLVLIAFWLPQLNIYSEKASPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWASQ 80

                         90
                 ....*....|.
gi 385281323  81 LTSTKTTLILS 91
Cdd:MTH00106  81 TNNLNTMLTMA 91
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
18-81 3.50e-21

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 79.39  E-value: 3.50e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 385281323  18 VLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLlpLPWAMQL 81
Cdd:pfam00507  1 LLLSRLLGPKRPNPEKLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVEVVFL--FPWAVSF 62
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 3-78 1.74e-15

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 65.53  E-value: 1.74e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 385281323   3 LILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLlpLPWA 78
Cdd:COG0838    8 ILIFLLVALGLALAMLLLSRLLGPKRPNPEKLSPYECGIEPVGDARIRFSVRYYLVALLFVIFDVEVVFL--FPWA 81
 
Name Accession Description Interval E-value
ND3 MTH00106
NADH dehydrogenase subunit 3; Provisional
 1-91 1.68e-50

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177168 [Multi-domain]  Cd Length: 115  Bit Score: 154.33  E-value: 1.68e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAMQ 80
Cdd:MTH00106   1 MNLMLTLLTNTLLASLLVLIAFWLPQLNIYSEKASPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWASQ 80

                         90
                 ....*....|.
gi 385281323  81 LTSTKTTLILS 91
Cdd:MTH00106  81 TNNLNTMLTMA 91
ND3 MTH00136
NADH dehydrogenase subunit 3; Provisional
 1-89 1.29e-37

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177194 [Multi-domain]  Cd Length: 116  Bit Score: 121.95  E-value: 1.29e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   1 MNLIL-MLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAM 79
Cdd:MTH00136   1 MNLITtILTITIALSLILAIVSFWLPQMTPDHEKLSPYECGFDPLGSARLPFSLRFFLVAILFLLFDLEIALLLPLPWGD 80

                         90
                 ....*....|
gi 385281323  80 QLTSTKTTLI 89
Cdd:MTH00136  81 QLPSPLLTFF 90
ND3 MTH00069
NADH dehydrogenase subunit 3; Provisional
 3-91 2.10e-34

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177141 [Multi-domain]  Cd Length: 114  Bit Score: 113.55  E-value: 2.10e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   3 LILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAMQLT 82
Cdd:MTH00069   2 IMLMLLISTILSLILITISFWLPLNNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPTPWASQLN 81


                 ....*....
gi 385281323  83 STKTTLILS 91
Cdd:MTH00069  82 TPTNTLFWS 90
ND3 MTH00113
NADH dehydrogenase subunit 3; Provisional
 1-91 1.56e-33

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177175 [Multi-domain]  Cd Length: 114  Bit Score: 111.51  E-value: 1.56e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAMQ 80
Cdd:MTH00113   1 MNLISMLTISLALSTILTTLNFWLTQTKPDNEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAIN 80

                         90
                 ....*....|.
gi 385281323  81 LTSTKTTLILS 91
Cdd:MTH00113  81 LTTPTTTLTWA 91
ND3 MTH00042
NADH dehydrogenase subunit 3; Validated
 1-91 4.89e-27

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 177117 [Multi-domain]  Cd Length: 116  Bit Score: 95.05  E-value: 4.89e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAMQ 80
Cdd:MTH00042   2 TNLIFFLLIILILTSLLLLAGHFLPSRSPDLEKSSPYECGFDPLNSARLPFSFRFFLVAILFLLFDLEIALLFPLPPATL 81

                         90
                 ....*....|.
gi 385281323  81 LTSTKTTLILS 91
Cdd:MTH00042  82 ITNPSTLLPIS 92
ND3 MTH00203
NADH dehydrogenase subunit 3; Provisional
 3-91 5.61e-25

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214456 [Multi-domain]  Cd Length: 112  Bit Score: 89.57  E-value: 5.61e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   3 LILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAMQLT 82
Cdd:MTH00203   4 IMLFFLIALLLSLILLFIAFWLPKVNPDGEKLSPYECGFDPLGSARLPFSLQFFLVALSFLLFDLEIALLLPLPWSNQLS 83


                 ....*....
gi 385281323  83 STKTTLILS 91
Cdd:MTH00203  84 SLSLLLAFL 92
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
18-81 3.50e-21

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 79.39  E-value: 3.50e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 385281323  18 VLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLlpLPWAMQL 81
Cdd:pfam00507  1 LLLSRLLGPKRPNPEKLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVEVVFL--FPWAVSF 62
ND3 MTH00148
NADH dehydrogenase subunit 3; Provisional
 1-75 1.50e-20

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214433 [Multi-domain]  Cd Length: 117  Bit Score: 78.75  E-value: 1.50e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLPQLYLY-LEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPL 75
Cdd:MTH00148   2 LSILLSLLFALILSPVLLLLGLVLSKRSYSdREKSSPFECGFDPISSARSPFSLRFFLLAILFLVFDVEIVLLFPV 77
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 2-91 1.01e-17

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 71.35  E-value: 1.01e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   2 NLILMLIINFSLATIVVLIAFWL-PQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAMQ 80
Cdd:MTH00161   1 MILIILLIILLISIILMILASLLsKKSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFK 80

                         90
                 ....*....|.
gi 385281323  81 LTSTKTTLILS 91
Cdd:MTH00161  81 TSNMMSWLITS 91
ND3 MTH00202
NADH dehydrogenase subunit 3; Provisional
 1-89 2.63e-17

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214455 [Multi-domain]  Cd Length: 117  Bit Score: 70.41  E-value: 2.63e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLP-QLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAM 79
Cdd:MTH00202   2 LLILFMSILSILISSLLFLVSWMLSfRSLMDREKSSPFECGFDPKESARLPFSMRFFLLAVIFLVFDIEIALLLPLPLVL 81

                         90
                 ....*....|
gi 385281323  80 QLTSTKTTLI 89
Cdd:MTH00202  82 KSSWSKGGLL 91
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 3-78 1.74e-15

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 65.53  E-value: 1.74e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 385281323   3 LILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLlpLPWA 78
Cdd:COG0838    8 ILIFLLVALGLALAMLLLSRLLGPKRPNPEKLSPYECGIEPVGDARIRFSVRYYLVALLFVIFDVEVVFL--FPWA 81
ND3 MTH00012
NADH dehydrogenase subunit 3; Validated
 5-91 2.98e-15

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164588 [Multi-domain]  Cd Length: 117  Bit Score: 65.26  E-value: 2.98e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385281323   5 LMLIINFSLATIVVLIAFWLPQLYLY-LEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAMQLTS 83
Cdd:MTH00012   6 IPMMISLILPPLVLGAAWVLAARSTAdREKTSPFECGFDPHKTARIPFSLRFFLLAIIFIVFDIEIVLLMPVPTILMTST 85


                 ....*...
gi 385281323  84 TKTTLILS 91
Cdd:MTH00012  86 SKTVVYTS 93
ND3 MTH00055
NADH dehydrogenase subunit 3; Provisional
 1-74 8.33e-15

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177128 [Multi-domain]  Cd Length: 118  Bit Score: 63.96  E-value: 8.33e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLP 74
Cdd:MTH00055   6 LGIFILLLFSIGLSTVISGASYIVGVKQPDSEKVSVYECGFDPFESSRIPFSVRFFLVGILFLIFDLEISFLFP 79
ND3 MTH00018
NADH dehydrogenase subunit 3; Validated
 1-74 3.74e-13

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164592 [Multi-domain]  Cd Length: 113  Bit Score: 59.69  E-value: 3.74e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLP 74
Cdd:MTH00018   1 YGLFILLIFSVVLSALFSGASYFLGVKQPDREKVSAYECGFDPFGFPGRPFSIRFFLIGILFLIFDLEISFLFP 74
PRK06602 PRK06602
NADH:ubiquinone oxidoreductase subunit A; Validated
 32-78 4.13e-13

NADH:ubiquinone oxidoreductase subunit A; Validated


Pssm-ID: 180638 [Multi-domain]  Cd Length: 121  Bit Score: 59.88  E-value: 4.13e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 385281323  32 EKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLlpLPWA 78
Cdd:PRK06602  40 EKNSPYESGFEAFGDARMKFDVRFYLVAILFVIFDLEAAFL--FPWA 84
ND3 MTH00030
NADH dehydrogenase subunit 3; Provisional
 32-74 6.00e-10

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 164603 [Multi-domain]  Cd Length: 123  Bit Score: 51.86  E-value: 6.00e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 385281323  32 EKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLP 74
Cdd:MTH00030  42 EKSSIYECGFDPFGKIRTPFTIKFVLVGILFMIFDIEISFLFP 84
ndhC CHL00022
NADH dehydrogenase subunit 3
 11-79 1.21e-05

NADH dehydrogenase subunit 3


Pssm-ID: 176964 [Multi-domain]  Cd Length: 120  Bit Score: 40.36  E-value: 1.21e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 385281323  11 FSLATIVVLIAFWLPQLYLYL----EKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLlpLPWAM 79
Cdd:CHL00022  14 LIISSLIPILAFLISGLLAPIskgpEKLSSYESGIEPMGDAWLQFRIRYYMFALVFVVFDVETVFL--YPWAM 84
ND3 MTH00092
NADH dehydrogenase subunit 3; Provisional
 1-73 1.11e-04

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177155  Cd Length: 111  Bit Score: 37.57  E-value: 1.11e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 385281323   1 MNLILMLIINFSLATIVVLIAFWLPQLYLYLEKSSPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLL 73
Cdd:MTH00092   2 LVLIFVFLFTLLLLMLLYLLNFFLSVKKFDLLKVSSFECGFESVGKIQNSFSIHFFKIMLMFVIFDLEIVMFL 74
ND3 MTH00060
NADH dehydrogenase subunit 3; Provisional
 35-76 2.40e-03

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177132  Cd Length: 116  Bit Score: 34.10  E-value: 2.40e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 385281323  35 SPYECGFDPLGSARLPFSMKFFLVAITFLLFDLEIALLLPLP 76
Cdd:MTH00060  39 SSFECGFFSSGLSENCFSFTYFFLLVFFVIFDLEISLLLNMP 80
PRK08489 PRK08489
NAD(P)H-quinone oxidoreductase subunit 3;
33-78 7.57e-03

NAD(P)H-quinone oxidoreductase subunit 3;


Pssm-ID: 181448 [Multi-domain]  Cd Length: 129  Bit Score: 33.10  E-value: 7.57e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 385281323  33 KSSPYECGFDPLGSARlPFSMKFFLVAITFLLFDLEIALLlpLPWA 78
Cdd:PRK08489  47 KLAIYECGPEPVKQPN-RISSHFYIMALLFILFDVEIVFM--FPWA 89
PLN00101 PLN00101
Photosystem I light-harvesting complex type 4 protein; Provisional
 23-59 7.69e-03

Photosystem I light-harvesting complex type 4 protein; Provisional


Pssm-ID: 215055 [Multi-domain]  Cd Length: 250  Bit Score: 33.73  E-value: 7.69e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 385281323  23 WLPQLY--LYLEKSSPYECGFDPLGSARLPFSMKFFLVA 59
Cdd:PLN00101  56 WLPGLAspGYLNGSLPGDNGFDPLGLAEDPENLKWFVQA 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH