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Conserved domains on  [gi|403063729|gb|AFR12392|]
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glycerol-3-phosphate dehydrogenase, partial [Drosophila nr. medialis 3 KNM-2012]

Protein Classification

glycerol-3-phosphate dehydrogenase family protein( domain architecture ID 11496765)

glycerol-3-phosphate dehydrogenase family protein is similar to human L-alpha-glycerol-3-phosphate dehydrogenase 1 (GPD1), which catalyzes the reversible biological conversion of dihydroxyacetone (DHAP) to glycerol-3-phosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 1-254 1.76e-140

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


:

Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 397.87  E-value: 1.76e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729    1 DILIFVVPHQFIPNFCKQLLGKIKPTAIAISLIKGFDKAEGGgIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETT 80
Cdd:TIGR03376  84 DILVFVIPHQFLEGICKQLKGHVKPNARAISCIKGLEVSKDG-VKLLSDIIEEELGIPCGVLSGANLANEVAKEKFSETT 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   81 IGCTD----KKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDV 156
Cdd:TIGR03376 163 VGYRDpadfDVDARVLKALFHRPYFRVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLEMIKFARM 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  157 FYPGSKLSTFFESCGVADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLF 236
Cdd:TIGR03376 243 FFPTGEVTFTFESCGVADLITTCLGGRNFKVGRAFAKTGKSLEELEKELLNGQSLQGVATAKEVHELLKNKNKDDEFPLF 322

                         250
                  ....*....|....*...
gi 403063729  237 TAIHKICTNQLKPNDLID 254
Cdd:TIGR03376 323 EAVYQILYEGLPPKKLPE 340
 
Name Accession Description Interval E-value
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 1-254 1.76e-140

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 397.87  E-value: 1.76e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729    1 DILIFVVPHQFIPNFCKQLLGKIKPTAIAISLIKGFDKAEGGgIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETT 80
Cdd:TIGR03376  84 DILVFVIPHQFLEGICKQLKGHVKPNARAISCIKGLEVSKDG-VKLLSDIIEEELGIPCGVLSGANLANEVAKEKFSETT 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   81 IGCTD----KKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDV 156
Cdd:TIGR03376 163 VGYRDpadfDVDARVLKALFHRPYFRVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLEMIKFARM 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  157 FYPGSKLSTFFESCGVADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLF 236
Cdd:TIGR03376 243 FFPTGEVTFTFESCGVADLITTCLGGRNFKVGRAFAKTGKSLEELEKELLNGQSLQGVATAKEVHELLKNKNKDDEFPLF 322

                         250
                  ....*....|....*...
gi 403063729  237 TAIHKICTNQLKPNDLID 254
Cdd:TIGR03376 323 EAVYQILYEGLPPKKLPE 340
PTZ00345 PTZ00345
glycerol-3-phosphate dehydrogenase; Provisional
 1-254 8.35e-107

glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 240373 [Multi-domain]  Cd Length: 365  Bit Score: 313.11  E-value: 8.35e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   1 DILIFVVPHQFIPNFCKQL--LGKIKPTAIAISLIKGFdKAEGGGIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCE 78
Cdd:PTZ00345  95 DLLIFVIPHQFLESVLSQIkeNNNLKKHARAISLTKGI-IVENGKPVLCSDVIEEELGIPCCALSGANVANDVAREEFSE 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  79 TTIGCTDKKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFY 158
Cdd:PTZ00345 174 ATIGCEDKDDALIWQRLFDRPYFKINCVPDVIGVEVCGALKNIIALAAGFCDGLGLGTNTKSAIIRIGLEEMKLFGKIFF 253

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729 159 PGSKLSTFFESCGVADLITTCYGGRNRRVSEAFVTSG--KTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLF 236
Cdd:PTZ00345 254 PNVMDETFFESCGLADLITTCLGGRNVRCAAEFAKRNgkKSWEEIEAELLNGQKLQGTVTLKEVYEVLESHDLKKEFPLF 333

                        250
                 ....*....|....*...
gi 403063729 237 TAIHKICTNQLKPNDLID 254
Cdd:PTZ00345 334 TVTYKIAFEGADPSSLID 351
NAD_Gly3P_dh_C pfam07479
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent ...
 113-254 1.47e-63

NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the C-terminal substrate-binding domain.


Pssm-ID: 462178 [Multi-domain]  Cd Length: 142  Bit Score: 195.30  E-value: 1.47e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  113 EVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFypGSKLSTFFESCGVADLITTCYGG--RNRRVSEA 190
Cdd:pfam07479   6 ELGGALKNVIAIAAGIADGLGLGDNAKAALITRGLAEMIRLGKAL--GAKPETFFGLAGLGDLIVTCTSGlsRNRRFGEA 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 403063729  191 FVTsGKTIEELEKEMlnGQKLQGPPTAEEVNYMLKNKGLEdkFPLFTAIHKICTNQLKPNDLID 254
Cdd:pfam07479  84 LGK-GKSLEEAEKEL--GQVAEGVYTAKAVYELAKKLGVE--MPIFEAVYRILYEGKSPEEALE 142
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 1-254 6.06e-59

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 189.48  E-value: 6.06e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   1 DILIFVVPHQFIPNFCKQLLGKIKPTAIAISLIKGFdkaEGGGIDLISHIITRHL--KIPCAVLMGANLANEVAEGNFCE 78
Cdd:COG0240   72 DLVLLAVPSQALREVLEQLAPLLPPGAPVVSATKGI---EPGTGLLMSEVIAEELpgALRIAVLSGPSFAEEVARGLPTA 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  79 TTIGCTDKKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFy 158
Cdd:COG0240  149 VVVASEDEEVAERLQELLSTPYFRVYTSDDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEMTRLGVAL- 227

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729 159 pGSKLSTFFESCGVADLITTCYG--GRNRRVSEAFVtSGKTIEELEKEMlnGQKLQGPPTAEEVNYMLKNKGLEdkFPLF 236
Cdd:COG0240  228 -GARPETFMGLAGLGDLVLTCTSdlSRNRRFGLALG-KGKSLEEALAEM--GMVAEGVYTAKAVYELAEKLGVE--MPIT 301

                        250
                 ....*....|....*...
gi 403063729 237 TAIHKICTNQLKPNDLID 254
Cdd:COG0240  302 EAVYAVLYEGKSPREAVE 319
 
Name Accession Description Interval E-value
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 1-254 1.76e-140

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 397.87  E-value: 1.76e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729    1 DILIFVVPHQFIPNFCKQLLGKIKPTAIAISLIKGFDKAEGGgIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETT 80
Cdd:TIGR03376  84 DILVFVIPHQFLEGICKQLKGHVKPNARAISCIKGLEVSKDG-VKLLSDIIEEELGIPCGVLSGANLANEVAKEKFSETT 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   81 IGCTD----KKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDV 156
Cdd:TIGR03376 163 VGYRDpadfDVDARVLKALFHRPYFRVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLEMIKFARM 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  157 FYPGSKLSTFFESCGVADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLF 236
Cdd:TIGR03376 243 FFPTGEVTFTFESCGVADLITTCLGGRNFKVGRAFAKTGKSLEELEKELLNGQSLQGVATAKEVHELLKNKNKDDEFPLF 322

                         250
                  ....*....|....*...
gi 403063729  237 TAIHKICTNQLKPNDLID 254
Cdd:TIGR03376 323 EAVYQILYEGLPPKKLPE 340
PTZ00345 PTZ00345
glycerol-3-phosphate dehydrogenase; Provisional
 1-254 8.35e-107

glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 240373 [Multi-domain]  Cd Length: 365  Bit Score: 313.11  E-value: 8.35e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   1 DILIFVVPHQFIPNFCKQL--LGKIKPTAIAISLIKGFdKAEGGGIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCE 78
Cdd:PTZ00345  95 DLLIFVIPHQFLESVLSQIkeNNNLKKHARAISLTKGI-IVENGKPVLCSDVIEEELGIPCCALSGANVANDVAREEFSE 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  79 TTIGCTDKKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFY 158
Cdd:PTZ00345 174 ATIGCEDKDDALIWQRLFDRPYFKINCVPDVIGVEVCGALKNIIALAAGFCDGLGLGTNTKSAIIRIGLEEMKLFGKIFF 253

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729 159 PGSKLSTFFESCGVADLITTCYGGRNRRVSEAFVTSG--KTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLF 236
Cdd:PTZ00345 254 PNVMDETFFESCGLADLITTCLGGRNVRCAAEFAKRNgkKSWEEIEAELLNGQKLQGTVTLKEVYEVLESHDLKKEFPLF 333

                        250
                 ....*....|....*...
gi 403063729 237 TAIHKICTNQLKPNDLID 254
Cdd:PTZ00345 334 TVTYKIAFEGADPSSLID 351
NAD_Gly3P_dh_C pfam07479
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent ...
 113-254 1.47e-63

NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the C-terminal substrate-binding domain.


Pssm-ID: 462178 [Multi-domain]  Cd Length: 142  Bit Score: 195.30  E-value: 1.47e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  113 EVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFypGSKLSTFFESCGVADLITTCYGG--RNRRVSEA 190
Cdd:pfam07479   6 ELGGALKNVIAIAAGIADGLGLGDNAKAALITRGLAEMIRLGKAL--GAKPETFFGLAGLGDLIVTCTSGlsRNRRFGEA 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 403063729  191 FVTsGKTIEELEKEMlnGQKLQGPPTAEEVNYMLKNKGLEdkFPLFTAIHKICTNQLKPNDLID 254
Cdd:pfam07479  84 LGK-GKSLEEAEKEL--GQVAEGVYTAKAVYELAKKLGVE--MPIFEAVYRILYEGKSPEEALE 142
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 1-254 6.06e-59

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 189.48  E-value: 6.06e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   1 DILIFVVPHQFIPNFCKQLLGKIKPTAIAISLIKGFdkaEGGGIDLISHIITRHL--KIPCAVLMGANLANEVAEGNFCE 78
Cdd:COG0240   72 DLVLLAVPSQALREVLEQLAPLLPPGAPVVSATKGI---EPGTGLLMSEVIAEELpgALRIAVLSGPSFAEEVARGLPTA 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  79 TTIGCTDKKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFy 158
Cdd:COG0240  149 VVVASEDEEVAERLQELLSTPYFRVYTSDDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEMTRLGVAL- 227

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729 159 pGSKLSTFFESCGVADLITTCYG--GRNRRVSEAFVtSGKTIEELEKEMlnGQKLQGPPTAEEVNYMLKNKGLEdkFPLF 236
Cdd:COG0240  228 -GARPETFMGLAGLGDLVLTCTSdlSRNRRFGLALG-KGKSLEEALAEM--GMVAEGVYTAKAVYELAEKLGVE--MPIT 301

                        250
                 ....*....|....*...
gi 403063729 237 TAIHKICTNQLKPNDLID 254
Cdd:COG0240  302 EAVYAVLYEGKSPREAVE 319
gpsA PRK00094
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
1-254 2.64e-47

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;


Pssm-ID: 234629 [Multi-domain]  Cd Length: 325  Bit Score: 159.46  E-value: 2.64e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   1 DILIFVVPHQFIPNFCKQLLGKIKPTAIAISLIKGFDKAEGggiDLISHIITRHL--KIPCAVLMGANLANEVAEGNFCE 78
Cdd:PRK00094  73 DLILVAVPSQALREVLKQLKPLLPPDAPIVWATKGIEPGTG---KLLSEVLEEELpdLAPIAVLSGPSFAKEVARGLPTA 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  79 TTIGCTDKKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFy 158
Cdd:PRK00094 150 VVIASTDEELAERVQELFHSPYFRVYTNTDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEITRLGVAL- 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729 159 pGSKLSTFFESCGVADLITTCYG--GRNRRVSEAFVtSGKTIEELEKEMlnGQKLQGPPTAEEVNYMLKNKGLEdkFPLF 236
Cdd:PRK00094 229 -GANPETFLGLAGLGDLVLTCTSplSRNRRFGLALG-QGKSLEEALAEI--GMVAEGVRTAKAVYELAKKLGVE--MPIT 302

                        250
                 ....*....|....*...
gi 403063729 237 TAIHKICTNQLKPNDLID 254
Cdd:PRK00094 303 EAVYAVLYEGKDPREAVE 320
NAD_Gly3P_dh_N pfam01210
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent ...
 1-88 3.67e-29

NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the N-terminal NAD-binding domain.


Pssm-ID: 395967 [Multi-domain]  Cd Length: 158  Bit Score: 107.66  E-value: 3.67e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729    1 DILIFVVPHQFIPNFCKQLLGKIKPTAIAISLIKGFdkaEGGGIDLISHIITRHLKI--PCAVLMGANLANEVAEGNFCE 78
Cdd:pfam01210  71 DIIVIVVPSQALREVLKQLKGLLKPDAILVSLSKGI---EPGTLKLLSEVIEEELGIqpPIAVLSGPSHAEEVAQGLPTA 147

                          90
                  ....*....|
gi 403063729   79 TTIGCTDKKY 88
Cdd:pfam01210 148 TVIASKDEEA 157
PRK12439 PRK12439
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 1-230 2.60e-28

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 171500 [Multi-domain]  Cd Length: 341  Bit Score: 109.87  E-value: 2.60e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   1 DILIFVVPHQFIPNFCKQLLGKIKPTAIAISLIKGFDKAEGGGI-DLISHIITRHlkiPCAVLMGANLANEVAEGNFCET 79
Cdd:PRK12439  79 DVVVMGVPSHGFRGVLTELAKELRPWVPVVSLVKGLEQGTNMRMsQIIEEVLPGH---PAGILAGPNIAREVAEGYAAAA 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  80 TIGCTDKKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFyp 159
Cdd:PRK12439 156 VLAMPDQHLATRLSPLFRTRRFRVYTTDDVVGVEMAGALKNVFAIAVGMGYSLGIGENTRAMVIARALREMTKLGVAM-- 233

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403063729 160 GSKLSTFFESCGVADLITTCYG--GRNRRVSEAfVTSGKTIEELEKEMlnGQKLQGPPTAEEVNYMLKNKGLE 230
Cdd:PRK12439 234 GGNPETFAGLAGMGDLIVTCTSqrSRNRHVGEQ-LGAGKPIDEIIASM--NQVAEGVKAASVVMEFADEYGLN 303
PRK14618 PRK14618
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 1-249 1.83e-27

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 237770 [Multi-domain]  Cd Length: 328  Bit Score: 107.65  E-value: 1.83e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   1 DILIFVVPHQFIPNFCKQLlgkikPTAIAI-SLIKGFdKAEGGGIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCET 79
Cdd:PRK14618  76 DFAVVAVPSKALRETLAGL-----PRALGYvSCAKGL-APDGGRLSELARVLEFLTQARVAVLSGPNHAEEIARFLPAAT 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  80 TIGCTDKKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFyp 159
Cdd:PRK14618 150 VVASPEPGLARRVQAAFSGPSFRVYTSRDRVGVELGGALKNVIALAAGMVDGLKLGDNAKAALITRGLREMVRFGVAL-- 227

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729 160 GSKLSTFFESCGVADLITTCYG--GRNRRVSEAFVtSGKTIEELEKEmlnGQKLQGPPTAEEVNYMLKNKGLEdkFPLFT 237
Cdd:PRK14618 228 GAEEATFYGLSGLGDLIATATSphSRNRAAGEAIV-RGVDREHLEAG---GKVVEGLYTVKALDAWAKAHGHD--LPIVE 301

                        250
                 ....*....|..
gi 403063729 238 AIHKICTNQLKP 249
Cdd:PRK14618 302 AVARVARGGWDP 313
PRK14619 PRK14619
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 1-221 3.44e-21

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 237771 [Multi-domain]  Cd Length: 308  Bit Score: 90.05  E-value: 3.44e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   1 DILIFVVPHQFIPNFCKQLLG-KIKPTAIAISLIKGFDKAeggGIDLISHII-TRHLKIPCAVLMGANLANEVAEGNFCE 78
Cdd:PRK14619  49 DVIVSAVSMKGVRPVAEQVQAlNLPPETIIVTATKGLDPE---TTRTPSQIWqAAFPNHPVVVLSGPNLSKEIQQGLPAA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  79 TTIGCTDKKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFy 158
Cdd:PRK14619 126 TVVASRDLAAAETVQQIFSSERFRVYTNSDPLGTELGGTLKNVIAIAAGVCDGLQLGTNAKAALVTRALPEMIRVGTHL- 204

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 403063729 159 pGSKLSTFFESCGVADLITTCYG--GRNRRVSEAfVTSGKTIEE-LEkemlngqKLQGppTAEEVN 221
Cdd:PRK14619 205 -GAQTETFYGLSGLGDLLATCTSplSRNYQVGYG-LAQGKSLEQiLA-------ELEG--TAEGVN 259
PRK14620 PRK14620
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 2-242 2.88e-13

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 173083 [Multi-domain]  Cd Length: 326  Bit Score: 68.32  E-value: 2.88e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729   2 ILIFVVPHQFIPNFCKQLLGK--IKPTAIAISlIKGFDKAEgggIDLISHIITRHLKI-PCAVLMGANLANEVAEGNFCE 78
Cdd:PRK14620  74 CIILAVPTQQLRTICQQLQDChlKKNTPILIC-SKGIEKSS---LKFPSEIVNEILPNnPIAILSGPSFAKEIAEKLPCS 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729  79 TTIGCTDKKYGKVLRDLFQANHFRVVVVGDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGlMEMIRFVDVFY 158
Cdd:PRK14620 150 IVLAGQNETLGSSLISKLSNENLKIIYSQDIIGVQIGAALKNIIAIACGIVLGKNLGNNAHAAVITKG-MNEIKTLYSAK 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403063729 159 PGS-KLSTFFESCGVADLITTCYGGRNRRVSEAF-VTSGKTIEELEKEmlNGQKLQGPPTAEEVNYMLKNkgLEDKFPLF 236
Cdd:PRK14620 229 NGSiDLNTLIGPSCLGDLILTCTTLHSRNMSFGFkIGNGFNINQILSE--GKSVIEGFSTVKPLISLAKK--LNIELPIC 304


                 ....*.
gi 403063729 237 TAIHKI 242
Cdd:PRK14620 305 ESIYNL 310
GPD_NAD_C_bact pfam20618
Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent ...
 170-239 1.42e-05

Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent glycerol-3-phosphate dehydrogenase (GPD) from bacteria and archaea. GPD catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate.


Pssm-ID: 466767 [Multi-domain]  Cd Length: 66  Bit Score: 41.71  E-value: 1.42e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403063729  170 CGVADLITTCYGG--RNRRVSEAfVTSGKTIEELEKEMLngqkLQGPPTAEEVNYML-KNKGLEdkFPLFTAI 239
Cdd:pfam20618   1 AGLGDLVLTCTSDlsRNRTFGLL-LGKGMTLAEAGNGQV----AEGVRTAKAVAAILaRAHNVE--MPILEAV 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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