recombination activating protein 2, partial [Pachyornis australis]
RAG2 and RAG2_PHD domain-containing protein( domain architecture ID 11976271)
RAG2 and RAG2_PHD domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
RAG2 super family | cl28748 | Recombination activating protein 2; V-D-J recombination is the combinatorial process by which ... |
43-319 | 0e+00 | |||||
Recombination activating protein 2; V-D-J recombination is the combinatorial process by which the huge range of immunoglobulin and T cell binding specificity is generated from a limited amount of genetic material. This process is synergistically activated by RAG1 and RAG2 in developing lymphocytes. Defects in RAG2 in humans are a cause of severe combined immunodeficiency B cell negative and Omenn syndrome. The actual alignment was detected with superfamily member pfam03089: Pssm-ID: 427128 Cd Length: 339 Bit Score: 568.98 E-value: 0e+00
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RAG2_PHD | pfam13341 | RAG2 PHD domain; This domain is found at the C-terminus of the RAG2 protein. The structure of ... |
417-480 | 5.03e-40 | |||||
RAG2 PHD domain; This domain is found at the C-terminus of the RAG2 protein. The structure of this domain has been shown bound to histone H3 trimethylated at lysine 4 (H3K4me3). : Pssm-ID: 404256 Cd Length: 78 Bit Score: 138.76 E-value: 5.03e-40
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Name | Accession | Description | Interval | E-value | |||||
RAG2 | pfam03089 | Recombination activating protein 2; V-D-J recombination is the combinatorial process by which ... |
43-319 | 0e+00 | |||||
Recombination activating protein 2; V-D-J recombination is the combinatorial process by which the huge range of immunoglobulin and T cell binding specificity is generated from a limited amount of genetic material. This process is synergistically activated by RAG1 and RAG2 in developing lymphocytes. Defects in RAG2 in humans are a cause of severe combined immunodeficiency B cell negative and Omenn syndrome. Pssm-ID: 427128 Cd Length: 339 Bit Score: 568.98 E-value: 0e+00
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RAG2_PHD | pfam13341 | RAG2 PHD domain; This domain is found at the C-terminus of the RAG2 protein. The structure of ... |
417-480 | 5.03e-40 | |||||
RAG2 PHD domain; This domain is found at the C-terminus of the RAG2 protein. The structure of this domain has been shown bound to histone H3 trimethylated at lysine 4 (H3K4me3). Pssm-ID: 404256 Cd Length: 78 Bit Score: 138.76 E-value: 5.03e-40
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PHD_RAG2 | cd15569 | PHD finger found in V(D)J recombination-activating protein 2 (RAG-2) and similar proteins; ... |
417-472 | 1.19e-34 | |||||
PHD finger found in V(D)J recombination-activating protein 2 (RAG-2) and similar proteins; RAG-2 is an essential component of the lymphoid-specific recombination activating gene RAG1/2 V(D)J recombinase mediating antigen-receptor gene assembly. It contains an acidic hinge region implicated in histone-binding, a non-canonical plant homeodomain (PHD) finger followed by a C-terminal extension of 40 amino acids that is essential for phosphoinositide (PtdIns)-binding. The PHD finger is a chromatin-binding module that specifically recognizes histone H3 trimethylated at lysine 4 (H3K4me3) and influences V(D)J recombination. Pssm-ID: 277044 Cd Length: 67 Bit Score: 123.87 E-value: 1.19e-34
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Name | Accession | Description | Interval | E-value | |||||
RAG2 | pfam03089 | Recombination activating protein 2; V-D-J recombination is the combinatorial process by which ... |
43-319 | 0e+00 | |||||
Recombination activating protein 2; V-D-J recombination is the combinatorial process by which the huge range of immunoglobulin and T cell binding specificity is generated from a limited amount of genetic material. This process is synergistically activated by RAG1 and RAG2 in developing lymphocytes. Defects in RAG2 in humans are a cause of severe combined immunodeficiency B cell negative and Omenn syndrome. Pssm-ID: 427128 Cd Length: 339 Bit Score: 568.98 E-value: 0e+00
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RAG2_PHD | pfam13341 | RAG2 PHD domain; This domain is found at the C-terminus of the RAG2 protein. The structure of ... |
417-480 | 5.03e-40 | |||||
RAG2 PHD domain; This domain is found at the C-terminus of the RAG2 protein. The structure of this domain has been shown bound to histone H3 trimethylated at lysine 4 (H3K4me3). Pssm-ID: 404256 Cd Length: 78 Bit Score: 138.76 E-value: 5.03e-40
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PHD_RAG2 | cd15569 | PHD finger found in V(D)J recombination-activating protein 2 (RAG-2) and similar proteins; ... |
417-472 | 1.19e-34 | |||||
PHD finger found in V(D)J recombination-activating protein 2 (RAG-2) and similar proteins; RAG-2 is an essential component of the lymphoid-specific recombination activating gene RAG1/2 V(D)J recombinase mediating antigen-receptor gene assembly. It contains an acidic hinge region implicated in histone-binding, a non-canonical plant homeodomain (PHD) finger followed by a C-terminal extension of 40 amino acids that is essential for phosphoinositide (PtdIns)-binding. The PHD finger is a chromatin-binding module that specifically recognizes histone H3 trimethylated at lysine 4 (H3K4me3) and influences V(D)J recombination. Pssm-ID: 277044 Cd Length: 67 Bit Score: 123.87 E-value: 1.19e-34
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Blast search parameters | ||||
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