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Conserved domains on  [gi|407355381|gb|AFU08256|]
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middle T antigen [Alphapolyomavirus mauratus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03102 PHA03102
Small T antigen; Reviewed
 7-161 5.45e-68

Small T antigen; Reviewed


:

Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 211.84  E-value: 5.45e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 407355381   7 KEEKQTLITLLDLEPQYWGDYGRMQKCYKKKCLQLHPDKGGNEELMQQLNTLWTKLKDGLYRVRLLLGPSQVRRLGKDQW 86
Cdd:PHA03102   1 REESKELMDLLGLPRSAWGNLPLMRKAYLRKCLEFHPDKGGDEEKMKELNTLYKKFRESVKSLRDLDGEEDSSSEEEDVP 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 407355381  87 NLSLQQTFSGTYFRRLCRLPITCLRNKGvSTCNCILCLLRKQHfLLKKSWRVPCLVLGECYCIDCFALWFGLPVT 161
Cdd:PHA03102  81 SGYVGATFGDRVNALYCKDWDTCLKNLS-SLCKCIFCLLRKQH-RLKQKLRPEPLVWGECYCYKCFRQWFGLDIT 153
 
Name Accession Description Interval E-value
PHA03102 PHA03102
Small T antigen; Reviewed
 7-161 5.45e-68

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 211.84  E-value: 5.45e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 407355381   7 KEEKQTLITLLDLEPQYWGDYGRMQKCYKKKCLQLHPDKGGNEELMQQLNTLWTKLKDGLYRVRLLLGPSQVRRLGKDQW 86
Cdd:PHA03102   1 REESKELMDLLGLPRSAWGNLPLMRKAYLRKCLEFHPDKGGDEEKMKELNTLYKKFRESVKSLRDLDGEEDSSSEEEDVP 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 407355381  87 NLSLQQTFSGTYFRRLCRLPITCLRNKGvSTCNCILCLLRKQHfLLKKSWRVPCLVLGECYCIDCFALWFGLPVT 161
Cdd:PHA03102  81 SGYVGATFGDRVNALYCKDWDTCLKNLS-SLCKCIFCLLRKQH-RLKQKLRPEPLVWGECYCYKCFRQWFGLDIT 153
Papo_T_antigen pfam02380
T-antigen specific domain; This domain represents a conserved region in papovavirus small and ...
 89-182 2.87e-41

T-antigen specific domain; This domain represents a conserved region in papovavirus small and middle T-antigens. It is found as the N-terminal domain in the small T-antigen, and is centrally located in the middle T-antigen.


Pssm-ID: 367062  Cd Length: 93  Bit Score: 140.99  E-value: 2.87e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 407355381   89 SLQQTFSGTYFRRLCRLPITCLRNKGvSTCNCILCLLRKQHFLLKKSWRVPCLVLGECYCIDCFALWFGLPVTNMLVPLY 168
Cdd:pfam02380   1 VLGATFGDKYDALYCKDWPTCLKNVS-SNCNCILCLLRKQHKNRKKFLRKPPLVWGECYCYDCYRQWFGLPLTEETLFLW 79

                          90
                  ....*....|....
gi 407355381  169 AQFLAPIPVDWLDL 182
Cdd:pfam02380  80 AQIIANTPFRDLKL 93
DnaJ smart00271
DnaJ molecular chaperone homology domain;
16-64 2.49e-07

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 47.23  E-value: 2.49e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 407355381    16 LLDLEPQywGDYGRMQKCYKKKCLQLHPDKGGN-----EELMQQLNTLWTKLKD 64
Cdd:smart00271   6 ILGVPRD--ASLDEIKKAYRKLALKYHPDKNPGdkeeaEEKFKEINEAYEVLSD 57
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
34-70 9.16e-04

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 38.16  E-value: 9.16e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 407355381  34 YKKKCLQLHPDKGGN-----EELMQQLNTLWTKLKDGLYRVR 70
Cdd:COG2214   26 YRRLAKLLHPDRGGElkalaEELFQRLNEAYEVLSDPERRAE 67
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 31-64 2.84e-03

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 35.60  E-value: 2.84e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 407355381  31 QKCYKKKCLQLHPDKGGN----EELMQQLNTLWTKLKD 64
Cdd:cd06257   18 KKAYRKLALKYHPDKNPDdpeaEEKFKEINEAYEVLSD 55
 
Name Accession Description Interval E-value
PHA03102 PHA03102
Small T antigen; Reviewed
 7-161 5.45e-68

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 211.84  E-value: 5.45e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 407355381   7 KEEKQTLITLLDLEPQYWGDYGRMQKCYKKKCLQLHPDKGGNEELMQQLNTLWTKLKDGLYRVRLLLGPSQVRRLGKDQW 86
Cdd:PHA03102   1 REESKELMDLLGLPRSAWGNLPLMRKAYLRKCLEFHPDKGGDEEKMKELNTLYKKFRESVKSLRDLDGEEDSSSEEEDVP 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 407355381  87 NLSLQQTFSGTYFRRLCRLPITCLRNKGvSTCNCILCLLRKQHfLLKKSWRVPCLVLGECYCIDCFALWFGLPVT 161
Cdd:PHA03102  81 SGYVGATFGDRVNALYCKDWDTCLKNLS-SLCKCIFCLLRKQH-RLKQKLRPEPLVWGECYCYKCFRQWFGLDIT 153
Papo_T_antigen pfam02380
T-antigen specific domain; This domain represents a conserved region in papovavirus small and ...
 89-182 2.87e-41

T-antigen specific domain; This domain represents a conserved region in papovavirus small and middle T-antigens. It is found as the N-terminal domain in the small T-antigen, and is centrally located in the middle T-antigen.


Pssm-ID: 367062  Cd Length: 93  Bit Score: 140.99  E-value: 2.87e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 407355381   89 SLQQTFSGTYFRRLCRLPITCLRNKGvSTCNCILCLLRKQHFLLKKSWRVPCLVLGECYCIDCFALWFGLPVTNMLVPLY 168
Cdd:pfam02380   1 VLGATFGDKYDALYCKDWPTCLKNVS-SNCNCILCLLRKQHKNRKKFLRKPPLVWGECYCYDCYRQWFGLPLTEETLFLW 79

                          90
                  ....*....|....
gi 407355381  169 AQFLAPIPVDWLDL 182
Cdd:pfam02380  80 AQIIANTPFRDLKL 93
PHA02624 PHA02624
large T antigen; Provisional
 1-86 2.10e-30

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 123.17  E-value: 2.10e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 407355381   1 MDRILTKEEKQTLITLLDLEPQYWGDYGRMQKCYKKKCLQLHPDKGGNEELMQQLNTLWTKLKDGLYRVRLLLGPSQVRR 80
Cdd:PHA02624   1 MDKTLSREESKELMDLLGLPMAAWGNLPLMRKAYLRKCKEYHPDKGGDEEKMKRLNSLYKKLQEGVKSARQSFGTQDSSE 80


                 ....*....
gi 407355381  81 L---GKDQW 86
Cdd:PHA02624  81 IptyGTPEW 89
DnaJ smart00271
DnaJ molecular chaperone homology domain;
16-64 2.49e-07

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 47.23  E-value: 2.49e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 407355381    16 LLDLEPQywGDYGRMQKCYKKKCLQLHPDKGGN-----EELMQQLNTLWTKLKD 64
Cdd:smart00271   6 ILGVPRD--ASLDEIKKAYRKLALKYHPDKNPGdkeeaEEKFKEINEAYEVLSD 57
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
34-70 9.16e-04

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 38.16  E-value: 9.16e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 407355381  34 YKKKCLQLHPDKGGN-----EELMQQLNTLWTKLKDGLYRVR 70
Cdd:COG2214   26 YRRLAKLLHPDRGGElkalaEELFQRLNEAYEVLSDPERRAE 67
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 31-64 2.84e-03

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 35.60  E-value: 2.84e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 407355381  31 QKCYKKKCLQLHPDKGGN----EELMQQLNTLWTKLKD 64
Cdd:cd06257   18 KKAYRKLALKYHPDKNPDdpeaEEKFKEINEAYEVLSD 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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