NCBI Conserved Domain Search

Conserved domains on [gi|663511184|gb|AIF01788|]

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putative ABC-type peptide transport system, ATPase component 2 (ABC.PE.A1) [uncultured marine group II/III euryarchaeote KM3_14_E02]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11468491)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including dipeptides and oligopeptides

CATH: 3.40.50.300

Gene Ontology: GO:0005524|GO:0016887|GO:0140359|GO:0042626

PubMed: 25750732|24638992

SCOP: 4003976

TCDB: 3.A.1

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

5-331

0e+00

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 562.43 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   5 SRDGKVLIEVKGMKKWFPIKGGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE 84
Cdd:COG4608    1 AAMAEPLLEVRDLKKHFPVRGGLFGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  85 DIRTIPD---RELRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSG 161
Cdd:COG4608   81 DITGLSGrelRPLRRRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHEFSG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 162 GQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:COG4608  161 GQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 242 NTADLFDKPAHPYTHALMSAIPEPSLEkASRERIVLSGDVPSPANPPPGCRFHTRCPIAVEgVCDVVDPPLETIDfDDHA 321
Cdd:COG4608  241 PRDELYARPLHPYTQALLSAVPVPDPE-RRRERIVLEGDVPSPLNPPSGCRFHTRCPYAQD-RCATEEPPLREVG-PGHQ 317

                        330
                 ....*....|
gi 663511184 322 VACHFPLGPG 331
Cdd:COG4608  318 VACHLAEEGS 327

Name

Accession

Description

Interval

E-value

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

5-331

0e+00

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 562.43 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   5 SRDGKVLIEVKGMKKWFPIKGGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE 84
Cdd:COG4608    1 AAMAEPLLEVRDLKKHFPVRGGLFGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  85 DIRTIPD---RELRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSG 161
Cdd:COG4608   81 DITGLSGrelRPLRRRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHEFSG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 162 GQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:COG4608  161 GQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 242 NTADLFDKPAHPYTHALMSAIPEPSLEkASRERIVLSGDVPSPANPPPGCRFHTRCPIAVEgVCDVVDPPLETIDfDDHA 321
Cdd:COG4608  241 PRDELYARPLHPYTQALLSAVPVPDPE-RRRERIVLEGDVPSPLNPPSGCRFHTRCPYAQD-RCATEEPPLREVG-PGHQ 317

                        330
                 ....*....|
gi 663511184 322 VACHFPLGPG 331
Cdd:COG4608  318 VACHLAEEGS 327

dppF

PRK11308

dipeptide transporter ATP-binding subunit; Provisional

7-325

1.72e-138

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 396.26 E-value: 1.72e-138

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   7 DGKVLIEVKGMKKWFPIKGGMLSEVKiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRvLLGLI-PITDGSVLYDGED 85
Cdd:PRK11308   1 SQQPLLQAIDLKKHYPVKRGLFKPER-LVKALDGVSFTLERGKTLAVVGESGCGKSTLAR-LLTMIeTPTGGELYYQGQD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  86 IrTIPDRE----LRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSG 161
Cdd:PRK11308  79 L-LKADPEaqklLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 162 GQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:PRK11308 158 GQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 242 NTADLFDKPAHPYTHALMSAIPEPSlEKASRERIVLSGDVPSPANPPPGCRFHTRCPIAVEgVCDVVDPPLEtiDFDDHA 321
Cdd:PRK11308 238 TKEQIFNNPRHPYTQALLSATPRLN-PDDRRERIKLTGELPSPLNPPPGCAFNARCPRAFG-RCRQEQPQLR--DYDGRL 313


                 ....
gi 663511184 322 VACH 325
Cdd:PRK11308 314 VACF 317

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

11-241

9.79e-116

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 334.86 E-value: 9.79e-116

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPIKGGmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:cd03257    1 LLEVKNLSVSFPTGGG-------SVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DREL---RRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQK-VADVLDSVGLKREHMNRFPHEFSGGQKQR 166
Cdd:cd03257   74 RRLRkirRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEaVLLLLVGVGLPEEVLNRYPHELSGGQRQR 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 167 LALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:cd03257  154 VAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228

nickel_nikE

TIGR02769

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...

11-262

1.58e-72

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 226.23 E-value: 1.58e-72

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   11 LIEVKGMKKWFpiKGGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIp 90
Cdd:TIGR02769   2 LLEVRDVTHTY--RTGGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQL- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   91 DRE----LRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQ-VNRLAEGAELtQKVADVLDSVGLKREHMNRFPHEFSGGQKQ 165
Cdd:TIGR02769  79 DRKqrraFRRDVQLVFQDSPSAVNPRMTVRQIIGEPLRhLTSLDESEQK-ARIAELLDMVGLRSEDADKLPRQLSGGQLQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  166 RLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTAD 245
Cdd:TIGR02769 158 RINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQ 237

                         250
                  ....*....|....*..
gi 663511184  246 LFDKpAHPYTHALMSAI 262
Cdd:TIGR02769 238 LLSF-KHPAGRNLQSAV 253

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

38-187

5.17e-45

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 151.26 E-value: 5.17e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggSMNPRMSVRS 117
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDP--QLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184  118 IVGEPLQVNRLAEgAELTQKVADVLDSVGLK---REHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTS 187
Cdd:pfam00005  79 NLRLGLLLKGLSK-REKDARAEEALEKLGLGdlaDRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

GguA

NF040905

sugar ABC transporter ATP-binding protein;

11-239

9.67e-22

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 96.01 E-value: 9.67e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPikgGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPIT--DGSVLYDGE--DI 86
Cdd:NF040905   1 ILEMRGITKTFP---G--------VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGsyEGEILFDGEvcRF 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  87 RTIPDRElRRRMQIVFQDPggSMNPRMSV-RSI-VGEPLQVNRLAEGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQK 164
Cdd:NF040905  70 KDIRDSE-ALGIVIIHQEL--ALIPYLSIaENIfLGNERAKRGVIDWNETNRRARELLAKVGL-DESPDTLVTDIGVGKQ 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 165 QRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVE 239
Cdd:NF040905 146 QLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGRTIE 219

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

37-229

9.53e-20

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 85.75 E-value: 9.53e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVlydgedirtipDRELRRRMQIVFQdpggsmnprmsvR 116
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-----------RRAGGARVAYVPQ------------R 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGE--PLQVNRLAE-------------GAELTQKVADVLDSVGLKREHMNRFpHEFSGGQKQRLALARALSLDPEFIL 181
Cdd:NF040873  64 SEVPDslPLTVRDLVAmgrwarrglwrrlTRDDRAAVDDALERVGLADLAGRQL-GELSGGQRQRALLAQGLAQEADLLL 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 663511184 182 LDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRV 229
Cdd:NF040873 143 LDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

37-270

3.84e-18

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 85.95 E-value: 3.84e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTiPDRELRRR---MQIVFqdpggsmnprm 113
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDA-GDIATRRRvgyMSQAF----------- 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 svrSIVGEpLQV--N-----RL--AEGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDE 184
Cdd:NF033858 349 ---SLYGE-LTVrqNlelhaRLfhLPAAEIAARVAEMLERFDL-ADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDE 423

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 185 PTSALDVSVQAQVLNLLEEIQEKLGLTfVFI-THALNVVNHiSDRVAVMYLGKIVEIantadlfDKPAhpythALMSAIP 263
Cdd:NF033858 424 PTSGVDPVARDMFWRLLIELSREDGVT-IFIsTHFMNEAER-CDRISLMHAGRVLAS-------DTPA-----ALVAARG 489


                 ....*..
gi 663511184 264 EPSLEKA 270
Cdd:NF033858 490 AATLEEA 496

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

35-190

4.12e-13

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 70.54 E-value: 4.12e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLgrvlLGLIP----ITDGSVLYDGEDIRtipDRELRRRM--QIVF--QDPG 106
Cdd:NF033858  14 TVALDDVSLDIPAGCMVGLIGPDGVGKSSL----LSLIAgarkIQQGRVEVLGGDMA---DARHRRAVcpRIAYmpQGLG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNPRMSVRsivgEPLQ-VNRL--AEGAELTQKVADVLDSVGLKRehmnrFPH----EFSGGQKQRLALARALSLDPEF 179
Cdd:NF033858  87 KNLYPTLSVF----ENLDfFGRLfgQDAAERRRRIDELLRATGLAP-----FADrpagKLSGGMKQKLGLCCALIHDPDL 157

                        170
                 ....*....|.
gi 663511184 180 ILLDEPTSALD 190
Cdd:NF033858 158 LILDEPTTGVD 168

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

47-240

1.85e-12

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 64.32 E-value: 1.85e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    47 RGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLY-DGEDIRTIPDRELRRrmqivfqdpggsmnprmsvrsivgeplqv 125
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYiDGEDILEEVLDQLLL----------------------------- 51

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   126 nrlaegaeltqkvadvldsvglkrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVL-----NL 200
Cdd:smart00382  52 ------------------------IIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLlleelRL 107

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 663511184   201 LEEIQEKLGLTFVFITHalnVVNHISDRVAVMYLGKIVEI 240
Cdd:smart00382 108 LLLLKSEKNLTVILTTN---DEKDLGPALLRRRFDRRIVL 144

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

5-252

2.96e-08

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 54.74 E-value: 2.96e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   5 SRDGKVLIEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTlgrvllGLIPitdgsVLYDGE 84
Cdd:NF000106   7 SNGARNAVEVRGLVKHFG-----------EVKAVDGVDLDVREGTVLGVLGP*GAA**R------GALP-----AHV*GP 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  85 DIRTIP---------DRELRRRM---QIVFQDPGGSMNPRMSVRsIVGEPLQVNRlaegAELTQKVADVLDSVGLKrEHM 152
Cdd:NF000106  65 DAGRRPwrf*twcanRRALRRTIg*hRPVR*GRRESFSGRENLY-MIGR*LDLSR----KDARARADELLERFSLT-EAA 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 153 NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVM 232
Cdd:NF000106 139 GRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVI 217

                        250       260
                 ....*....|....*....|....*....
gi 663511184 233 YLGKIVEIANTADLFDK---------PAH 252
Cdd:NF000106 218 DRGRVIADGKVDELKTKvggrtlqirPAH 246

GguA

NF040905

sugar ABC transporter ATP-binding protein;

4-238

8.38e-08

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 53.64 E-value: 8.38e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   4 ESRDGKVLIEVKGMKKWFPIKggmlSEVKIhvraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGL---IPITdGSVL 80
Cdd:NF040905 250 TPKIGEVVFEVKNWTVYHPLH----PERKV----VDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRsygRNIS-GTVF 320

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  81 YDGE--DIRTIPD---------RELRRRMQIVFQDP-----GGSMNPRMSVRSIVGEPLQVnRLAEG--AELTQKVADVL 142
Cdd:NF040905 321 KDGKevDVSTVSDaidaglayvTEDRKGYGLNLIDDikrniTLANLGKVSRRGVIDENEEI-KVAEEyrKKMNIKTPSVF 399

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 143 DSVGlkrehmnrfphEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVV 222
Cdd:NF040905 400 QKVG-----------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPEL 467

                        250
                 ....*....|....*.
gi 663511184 223 NHISDRVAVMYLGKIV 238
Cdd:NF040905 468 LGMCDRIYVMNEGRIT 483

Name

Accession

Description

Interval

E-value

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

5-331

0e+00

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 562.43 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   5 SRDGKVLIEVKGMKKWFPIKGGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE 84
Cdd:COG4608    1 AAMAEPLLEVRDLKKHFPVRGGLFGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  85 DIRTIPD---RELRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSG 161
Cdd:COG4608   81 DITGLSGrelRPLRRRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHEFSG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 162 GQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:COG4608  161 GQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 242 NTADLFDKPAHPYTHALMSAIPEPSLEkASRERIVLSGDVPSPANPPPGCRFHTRCPIAVEgVCDVVDPPLETIDfDDHA 321
Cdd:COG4608  241 PRDELYARPLHPYTQALLSAVPVPDPE-RRRERIVLEGDVPSPLNPPSGCRFHTRCPYAQD-RCATEEPPLREVG-PGHQ 317

                        330
                 ....*....|
gi 663511184 322 VACHFPLGPG 331
Cdd:COG4608  318 VACHLAEEGS 327

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

11-327

3.45e-171

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 478.78 E-value: 3.45e-171

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPIKGGmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP---ITDGSVLYDGEDIR 87
Cdd:COG0444    1 LLEVRNLKVYFPTRRG-------VVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEILFDGEDLL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  88 TIPDRELR----RRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLK--REHMNRFPHEFSG 161
Cdd:COG0444   74 KLSEKELRkirgREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPdpERRLDRYPHELSG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 162 GQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:COG0444  154 GMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEG 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 242 NTADLFDKPAHPYTHALMSAIPEPslEKASRERIVLSGDVPSPANPPPGCRFHTRCPIAVEgVCDVVDPPLETIDfDDHA 321
Cdd:COG0444  234 PVEELFENPRHPYTRALLSSIPRL--DPDGRRLIPIPGEPPSLLNPPSGCRFHPRCPYAMD-RCREEEPPLREVG-PGHR 309


                 ....*.
gi 663511184 322 VACHFP 327
Cdd:COG0444  310 VACHLY 315

dppF

PRK11308

dipeptide transporter ATP-binding subunit; Provisional

7-325

1.72e-138

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 396.26 E-value: 1.72e-138

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   7 DGKVLIEVKGMKKWFPIKGGMLSEVKiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRvLLGLI-PITDGSVLYDGED 85
Cdd:PRK11308   1 SQQPLLQAIDLKKHYPVKRGLFKPER-LVKALDGVSFTLERGKTLAVVGESGCGKSTLAR-LLTMIeTPTGGELYYQGQD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  86 IrTIPDRE----LRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSG 161
Cdd:PRK11308  79 L-LKADPEaqklLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 162 GQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:PRK11308 158 GQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 242 NTADLFDKPAHPYTHALMSAIPEPSlEKASRERIVLSGDVPSPANPPPGCRFHTRCPIAVEgVCDVVDPPLEtiDFDDHA 321
Cdd:PRK11308 238 TKEQIFNNPRHPYTQALLSATPRLN-PDDRRERIKLTGELPSPLNPPPGCAFNARCPRAFG-RCRQEQPQLR--DYDGRL 313


                 ....
gi 663511184 322 VACH 325
Cdd:PRK11308 314 VACF 317

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

7-265

2.19e-138

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 403.68 E-value: 2.19e-138

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   7 DGKVLIEVKGMKKWFPIKGGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPiTDGSVLYDGEDI 86
Cdd:COG4172  271 DAPPLLEARDLKVWFPIKRGLFRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDL 349

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  87 RTIPDRE---LRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAE-GAELTQKVADVLDSVGLKREHMNRFPHEFSGG 162
Cdd:COG4172  350 DGLSRRAlrpLRRRMQVVFQDPFGSLSPRMTVGQIIAEGLRVHGPGLsAAERRARVAEALEEVGLDPAARHRYPHEFSGG 429

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 163 QKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIAN 242
Cdd:COG4172  430 QRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGP 509

                        250       260
                 ....*....|....*....|...
gi 663511184 243 TADLFDKPAHPYTHALMSAIPEP 265
Cdd:COG4172  510 TEQVFDAPQHPYTRALLAAAPLL 532

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

2-268

5.51e-138

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 401.97 E-value: 5.51e-138

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   2 TEESRDGKVLIEVKGMKKWFPIKGgmlsevKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLY 81
Cdd:COG1123  251 APAAAAAEPLLEVRNLSKRYPVRG------KGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILF 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  82 DGEDIRTIPD---RELRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHE 158
Cdd:COG1123  325 DGKDLTKLSRrslRELRRRVQMVFQDPYSSLNPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPDLADRYPHE 404

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 159 FSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:COG1123  405 LSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIV 484

                        250       260       270
                 ....*....|....*....|....*....|
gi 663511184 239 EIANTADLFDKPAHPYTHALMSAIPEPSLE 268
Cdd:COG1123  485 EDGPTEEVFANPQHPYTRALLAAVPSLDPA 514

PRK15079

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

7-324

2.16e-128

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 370.96 E-value: 2.16e-128

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   7 DGKVLIEVKGMKKWFPIKGG--MLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE 84
Cdd:PRK15079   4 GKKVLLEVADLKVHFDIKDGkqWFWQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  85 DIRTIPD---RELRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLA-EGAELTQKVADVLDSVGLKREHMNRFPHEFS 160
Cdd:PRK15079  84 DLLGMKDdewRAVRSDIQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKlSRQEVKDRVKAMMLKVGLLPNLINRYPHEFS 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 161 GGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEI 240
Cdd:PRK15079 164 GGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVEL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 241 ANTADLFDKPAHPYTHALMSA--IPEPSLEKASRERIvLSGDVPSPANPPPGCRFHTRCPIAVEGvCDVVDPPLETIdfD 318
Cdd:PRK15079 244 GTYDEVYHNPLHPYTKALMSAvpIPDPDLERNKTIQL-LEGELPSPINPPSGCVFRTRCPIAGPE-CAKTRPVLEGS--F 319


                 ....*.
gi 663511184 319 DHAVAC 324
Cdd:PRK15079 320 RHAVSC 325

DppF

COG1124

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

11-263

1.23e-117

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 340.24 E-value: 1.23e-117

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPIKGGmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:COG1124    1 MLEVRNLSVSYGQGGR-------RVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DRELRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAEltqKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALA 170
Cdd:COG1124   74 RKAFRRRVQMVFQDPYASLHPRHTVDRILAEPLRIHGLPDREE---RIAELLEQVGLPPSFLDRYPHQLSGGQRQRVAIA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 171 RALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:COG1124  151 RALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGP 230

                        250
                 ....*....|...
gi 663511184 251 AHPYTHALMSAIP 263
Cdd:COG1124  231 KHPYTRELLAASL 243

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

11-241

9.79e-116

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 334.86 E-value: 9.79e-116

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPIKGGmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:cd03257    1 LLEVKNLSVSFPTGGG-------SVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DREL---RRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQK-VADVLDSVGLKREHMNRFPHEFSGGQKQR 166
Cdd:cd03257   74 RRLRkirRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEaVLLLLVGVGLPEEVLNRYPHELSGGQRQR 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 167 LALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:cd03257  154 VAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228

PRK10261

glutathione transporter ATP-binding protein; Provisional

7-283

7.54e-90

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 281.74 E-value: 7.54e-90

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   7 DGKVLIEVKGMKKWFPIKGGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDI 86
Cdd:PRK10261 309 DGEPILQVRNLVTRFPLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRI 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  87 RTIPDREL---RRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQ 163
Cdd:PRK10261 389 DTLSPGKLqalRRDIQFIFQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYPHEFSGGQ 468

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 164 KQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANT 243
Cdd:PRK10261 469 RQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPR 548

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 663511184 244 ADLFDKPAHPYTHALMSAIPEPSLEKASRERIVLSGDVPS 283
Cdd:PRK10261 549 RAVFENPQHPYTRKLMAAVPVADPSRQRPQRVLLSDDLPS 588

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

11-289

1.71e-88

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 275.80 E-value: 1.71e-88

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPIKGGMlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP----ITDGSVLYDGEDI 86
Cdd:COG4172    6 LLSVEDLSVAFGQGGGT-------VEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPdpaaHPSGSILFDGQDL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  87 RTIPDRELRR----RMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLK--REHMNRFPHEFS 160
Cdd:COG4172   79 LGLSERELRRirgnRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPdpERRLDAYPHQLS 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 161 GGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEI 240
Cdd:COG4172  159 GGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQ 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 663511184 241 ANTADLFDKPAHPYTHALMSAipEPSLEKAsrerivlsgdvPSPANPPP 289
Cdd:COG4172  239 GPTAELFAAPQHPYTRKLLAA--EPRGDPR-----------PVPPDAPP 274

SapF

COG4167

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

11-261

2.69e-84

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 256.30 E-value: 2.69e-84

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPIKGGMLSEVKIHvrAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRT-- 88
Cdd:COG4167    4 LLEVRNLSKTFKYRTGLFRRQQFE--AVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEYgd 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  89 IPDRELRRRMqiVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLA 168
Cdd:COG4167   82 YKYRCKHIRM--IFQDPNTSLNPRLNIGQILEEPLRLNTDLTAEEREERIFATLRLVGLLPEHANFYPHMLSSGQKQRVA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 169 LARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFD 248
Cdd:COG4167  160 LARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVFA 239

                        250
                 ....*....|...
gi 663511184 249 KPAHPYTHALMSA 261
Cdd:COG4167  240 NPQHEVTKRLIES 252

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

1-329

6.14e-78

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 242.32 E-value: 6.14e-78

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   1 MTEESRDGKVLIEVKGMKKWFPIKGGMlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP---ITDG 77
Cdd:PRK09473   2 VPLAQQQADALLDVKDLRVTFSTPDGD-------VTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAangRIGG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  78 SVLYDGEDIRTIPDRELRR----RMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGL--KREH 151
Cdd:PRK09473  75 SATFNGREILNLPEKELNKlraeQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMpeARKR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 152 MNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAV 231
Cdd:PRK09473 155 MKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLV 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 232 MYLGKIVEIANTADLFDKPAHPYTHALMSAIPEpsLEKASRERIVLSGDVPSPANPPPGCRFHTRCPIAVEgVCDvVDPP 311
Cdd:PRK09473 235 MYAGRTMEYGNARDVFYQPSHPYSIGLLNAVPR--LDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAME-ICS-SAPP 310

                        330
                 ....*....|....*...
gi 663511184 312 LETIDfDDHAVACHFPLG 329
Cdd:PRK09473 311 LEEFG-PGRLRACFKPVE 327

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

5-260

2.47e-76

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 244.23 E-value: 2.47e-76

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   5 SRDGKVLIEVKGMKKWFPIKGGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPiTDGSVLYDGE 84
Cdd:PRK15134 269 PEPASPLLDVEQLQVAFPIRKGILKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLIN-SQGEIWFDGQ 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  85 DIRTIPDREL---RRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLA-EGAELTQKVADVLDSVGLKREHMNRFPHEFS 160
Cdd:PRK15134 348 PLHNLNRRQLlpvRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVHQPTlSAAQREQQVIAVMEEVGLDPETRHRYPAEFS 427

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 161 GGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEI 240
Cdd:PRK15134 428 GGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQ 507

                        250       260
                 ....*....|....*....|
gi 663511184 241 ANTADLFDKPAHPYTHALMS 260
Cdd:PRK15134 508 GDCERVFAAPQQEYTRQLLA 527

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

35-278

6.46e-75

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 240.19 E-value: 6.46e-75

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPIT---DGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSMNP 111
Cdd:COG1123   19 VPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEALRGRRIGMVFQDPMTQLNP 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 rMSVRSIVGEPLQvNRLAEGAELTQKVADVLDSVGLKReHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:COG1123   99 -VTVGDQIAEALE-NLGLSRAEARARVLELLEAVGLER-RLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALDV 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 192 SVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALMSAIPEPSLEKAS 271
Cdd:COG1123  176 TTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQALAAVPRLGAARGRAAPAAA 255


                 ....*..
gi 663511184 272 RERIVLS 278
Cdd:COG1123  256 AAEPLLE 262

nickel_nikE

TIGR02769

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...

11-262

1.58e-72

Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 226.23 E-value: 1.58e-72

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   11 LIEVKGMKKWFpiKGGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIp 90
Cdd:TIGR02769   2 LLEVRDVTHTY--RTGGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQL- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   91 DRE----LRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQ-VNRLAEGAELtQKVADVLDSVGLKREHMNRFPHEFSGGQKQ 165
Cdd:TIGR02769  79 DRKqrraFRRDVQLVFQDSPSAVNPRMTVRQIIGEPLRhLTSLDESEQK-ARIAELLDMVGLRSEDADKLPRQLSGGQLQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  166 RLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTAD 245
Cdd:TIGR02769 158 RINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQ 237

                         250
                  ....*....|....*..
gi 663511184  246 LFDKpAHPYTHALMSAI 262
Cdd:TIGR02769 238 LLSF-KHPAGRNLQSAV 253

AbcC

COG1135

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

12-275

5.56e-72

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 227.27 E-value: 5.56e-72

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIKGGmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD 91
Cdd:COG1135    2 IELENLSKTFPTKGG-------PVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 REL---RRRMQIVFQdpggSMN--PRMSVRSIVGEPLQVNRLaEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQR 166
Cdd:COG1135   75 RELraaRRKIGMIFQ----HFNllSSRTVAENVALPLEIAGV-PKAEIRKRVAELLELVGLS-DKADAYPSQLSGGQKQR 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 167 LALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADL 246
Cdd:COG1135  149 VGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDV 228

                        250       260
                 ....*....|....*....|....*....
gi 663511184 247 FDKPAHPYTHALMSAIPEPSLEKASRERI 275
Cdd:COG1135  229 FANPQSELTRRFLPTVLNDELPEELLARL 257

dppD

PRK11022

dipeptide transporter ATP-binding subunit; Provisional

36-328

7.57e-68

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 216.15 E-value: 7.57e-68

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP----ITDGSVLYDGEDIRTIPDRELRR----RMQIVFQDPGG 107
Cdd:PRK11022  21 RAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDypgrVMAEKLEFNGQDLQRISEKERRNlvgaEVAMIFQDPMT 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 108 SMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLK--REHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEP 185
Cdd:PRK11022 101 SLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPdpASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEP 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 186 TSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALMSAIPEP 265
Cdd:PRK11022 181 TTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPRHPYTQALLRALPEF 260

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184 266 SLEKASRERivLSGDVPSPANPPPGCRFHTRCPIAVEgVCDVVDPPLETIdfDDHAVACHFPL 328
Cdd:PRK11022 261 AQDKARLAS--LPGVVPGKYDRPNGCLLNPRCPYATD-RCRAEEPALNML--AGRQSKCHYPL 318

MlaF

COG1127

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...

7-257

3.71e-66

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 209.07 E-value: 3.71e-66

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   7 DGKVLIEVKGMKKWFpikGGmlseVKIHvravDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDI 86
Cdd:COG1127    1 MSEPMIEVRNLTKSF---GD----RVVL----DGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDI 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  87 RTIPDREL---RRRMQIVFQDPG--GSMNprmsvrsiVGE----PLQVN-RLAEgAELTQKVADVLDSVGLkREHMNRFP 156
Cdd:COG1127   70 TGLSEKELyelRRRIGMLFQGGAlfDSLT--------VFEnvafPLREHtDLSE-AEIRELVLEKLELVGL-PGAADKMP 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 157 HEFSGGQKQRLALARALSLDPEFILLDEPTSALD-VSVqAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLG 235
Cdd:COG1127  140 SELSGGMRKRVALARALALDPEILLYDEPTAGLDpITS-AVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADG 218

                        250       260
                 ....*....|....*....|..
gi 663511184 236 KIVEIANTADLFDKPaHPYTHA 257
Cdd:COG1127  219 KIIAEGTPEELLASD-DPWVRQ 239

PotA

COG3842

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...

35-254

3.88e-66

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 212.65 E-value: 3.88e-66

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDI-RTIPDRelrRRMQIVFQDPggSMNPRM 113
Cdd:COG3842   18 VTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVtGLPPEK---RNVGMVFQDY--ALFPHL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:COG3842   93 TVAENVAFGLRMRGVPK-AEIRARVAELLELVGLE-GLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLSALDAKL 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 194 QAQVLNLLEEIQEKLGLTFVFITH----ALNvvnhISDRVAVMYLGKIVEIANTADLFDKPAHPY 254
Cdd:COG3842  171 REEMREELRRLQRELGITFIYVTHdqeeALA----LADRIAVMNDGRIEQVGTPEEIYERPATRF 231

nikE

PRK10419

nickel ABC transporter ATP-binding protein NikE;

11-262

7.42e-65

nickel ABC transporter ATP-binding protein NikE;

Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 206.46 E-value: 7.42e-65

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPikGGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIp 90
Cdd:PRK10419   3 LLNVSGLSHHYA--HGGLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKL- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DRE----LRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQ-VNRLAEgAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQ 165
Cdd:PRK10419  80 NRAqrkaFRRDIQMVFQDSISAVNPRKTVREIIREPLRhLLSLDK-AERLARASEMLRAVDLDDSVLDKRPPQLSGGQLQ 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 166 RLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTAD 245
Cdd:PRK10419 159 RVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPVGD 238

                        250
                 ....*....|....*..
gi 663511184 246 LfDKPAHPYTHALMSAI 262
Cdd:PRK10419 239 K-LTFSSPAGRVLQNAV 254

PRK15112

peptide ABC transporter ATP-binding protein SapF;

9-261

2.24e-64

peptide ABC transporter ATP-binding protein SapF;

Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 205.41 E-value: 2.24e-64

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   9 KVLIEVKGMKKWFPIKGGMLSevKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrT 88
Cdd:PRK15112   2 ETLLEVRNLSKTFRYRTGWFR--RQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPL-H 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  89 IPDRELR-RRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRL 167
Cdd:PRK15112  79 FGDYSYRsQRIRMIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGLLPDHASYYPHMLAPGQKQRL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 168 ALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLF 247
Cdd:PRK15112 159 GLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVL 238

                        250
                 ....*....|....
gi 663511184 248 DKPAHPYTHALMSA 261
Cdd:PRK15112 239 ASPLHELTKRLIAG 252

ABC_MetN_methionine_transporter

cd03258

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...

11-250

1.35e-63

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 202.04 E-value: 1.35e-63

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPIKGGmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:cd03258    1 MIELKNVSKVFGDTGG-------KVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DREL---RRRMQIVFQDpGGSMNPRmSVRSIVGEPLQVNRLaEGAELTQKVADVLDSVGLKREHmNRFPHEFSGGQKQRL 167
Cdd:cd03258   74 GKELrkaRRRIGMIFQH-FNLLSSR-TVFENVALPLEIAGV-PKAEIEERVLELLELVGLEDKA-DAYPAQLSGGQKQRV 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 168 ALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLF 247
Cdd:cd03258  150 GIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVF 229


                 ...
gi 663511184 248 DKP 250
Cdd:cd03258  230 ANP 232

ABC_Carb_Solutes_like

cd03259

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...

35-241

2.73e-62

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 198.13 E-value: 2.73e-62

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRelRRRMQIVFQDPggSMNPRMS 114
Cdd:cd03259   13 VRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPE--RRNIGMVFQDY--ALFPHLT 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:cd03259   89 VAENIAFGLKLRGVPK-AEIRARVRELLELVGL-EGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLR 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 663511184 195 AQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:cd03259  167 EELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213

metN

PRK11153

DL-methionine transporter ATP-binding subunit; Provisional

12-281

4.27e-62

DL-methionine transporter ATP-binding subunit; Provisional

Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 201.95 E-value: 4.27e-62

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIKGGmlsevKIHvrAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD 91
Cdd:PRK11153   2 IELKNISKVFPQGGR-----TIH--ALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 RELRR-RMQI--VFQdpggSMNpRMSVRSIVGE---PLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQ 165
Cdd:PRK11153  75 KELRKaRRQIgmIFQ----HFN-LLSSRTVFDNvalPLELAGTPK-AEIKARVTELLELVGLS-DKADRYPAQLSGGQKQ 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 166 RLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTAD 245
Cdd:PRK11153 148 RVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSE 227

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 663511184 246 LFDKPAHPYTHALMSA-----IPEPSLEKASRERIVLSGDV 281
Cdd:PRK11153 228 VFSHPKHPLTREFIQStlhldLPEDYLARLQAEPTTGSGPL 268

ABC_Org_Solvent_Resistant

cd03261

ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...

12-254

7.70e-62

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 197.72 E-value: 7.70e-62

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFpikggmlSEVKIHvravDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRT--- 88
Cdd:cd03261    1 IELRGLTKSF-------GGRTVL----KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGlse 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  89 IPDRELRRRMQIVFQDpgGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHmNRFPHEFSGGQKQRLA 168
Cdd:cd03261   70 AELYRLRRRMGMLFQS--GALFDSLTVFENVAFPLREHTRLSEEEIREIVLEKLEAVGLRGAE-DLYPAELSGGMKKRVA 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 169 LARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFD 248
Cdd:cd03261  147 LARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226


                 ....*.
gi 663511184 249 KPaHPY 254
Cdd:cd03261  227 SD-DPL 231

ABC_PotA_N

cd03300

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...

34-251

2.31e-60

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 193.61 E-value: 2.31e-60

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRelRRRMQIVFQDPggSMNPRM 113
Cdd:cd03300   12 GFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPH--KRPVNTVFQNY--ALFPHL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:cd03300   88 TVFENIAFGLRLKKLPK-AEIKERVAEALDLVQLE-GYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKL 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184 194 QAQVLNLLEEIQEKLGLTFVFITH----ALNVvnhiSDRVAVMYLGKIVEIANTADLFDKPA 251
Cdd:cd03300  166 RKDMQLELKRLQKELGITFVFVTHdqeeALTM----SDRIAVMNKGKIQQIGTPEEIYEEPA 223

LolD

COG1136

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

9-239

5.25e-60

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 192.57 E-value: 5.25e-60

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   9 KVLIEVKGMKKWFPIKGGmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRT 88
Cdd:COG1136    2 SPLLELRNLTKSYGTGEG-------EVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  89 IPDRELR--RRMQI--VFQDPggsmN--PRMSVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGG 162
Cdd:COG1136   75 LSERELArlRRRHIgfVFQFF----NllPELTALENVALPLLLAGVSR-KERRERARELLERVGLG-DRLDHRPSQLSGG 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 163 QKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVE 239
Cdd:COG1136  149 QQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAAR-ADRVIRLRDGRIVS 224

GlnQ

COG1126

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...

11-262

6.91e-60

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 192.90 E-value: 6.91e-60

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFpikGGMlsevkiHVraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrTIP 90
Cdd:COG1126    1 MIEIENLHKSF---GDL------EV--LKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDL-TDS 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 D---RELRRRMQIVFQdpggSMN--PRMSVRSIVGE-PLQVNRLAEgAELTQKVADVLDSVGLkREHMNRFPHEFSGGQK 164
Cdd:COG1126   69 KkdiNKLRRKVGMVFQ----QFNlfPHLTVLENVTLaPIKVKKMSK-AEAEERAMELLERVGL-ADKADAYPAQLSGGQQ 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 165 QRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTA 244
Cdd:COG1126  143 QRVAIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPE 221

                        250
                 ....*....|....*...
gi 663511184 245 DLFDKPAHPYTHALMSAI 262
Cdd:COG1126  222 EFFENPQHERTRAFLSKV 239

EcfA2

COG1122

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...

35-247

1.99e-59

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];

Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 191.39 E-value: 1.99e-59

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGgsmnpRMS 114
Cdd:COG1122   14 TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRKVGLVFQNPD-----DQL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGE-----PLqvNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSAL 189
Cdd:COG1122   89 FAPTVEEdvafgPE--NLGLPREEIRERVEEALELVGLE-HLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGL 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 190 DVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLF 247
Cdd:COG1122  166 DPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVF 222

TauB

COG1116

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...

9-240

7.20e-59

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 190.69 E-value: 7.20e-59

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   9 KVLIEVKGMKKWFPIKGGmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRt 88
Cdd:COG1116    5 APALELRGVSKRFPTGGG-------GVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVT- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  89 ipdrELRRRMQIVFQDPggSMNPRMSVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLA 168
Cdd:COG1116   77 ----GPGPDRGVVFQEP--ALLPWLTVLDNVALGLELRGVPK-AERRERARELLELVGLA-GFEDAYPHQLSGGMRQRVA 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 169 LARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITH----ALnvvnHISDRVAVM--YLGKIVEI 240
Cdd:COG1116  149 IARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHdvdeAV----FLADRVVVLsaRPGRIVEE 222

ABC_MJ0796_LolCDE_FtsE

cd03255

ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...

12-237

1.38e-58

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.

Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 188.85 E-value: 1.38e-58

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIKGgmlsevkIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD 91
Cdd:cd03255    1 IELKNLSKTYGGGG-------EKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSE 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 REL----RRRMQIVFQDPggsmN--PRMSVRSIVGEPLQVNRLaEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQ 165
Cdd:cd03255   74 KELaafrRRHIGFVFQSF----NllPDLTALENVELPLLLAGV-PKKERRERAEELLERVGLG-DRLNHYPSELSGGQQQ 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184 166 RLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHiSDRVAVMYLGKI 237
Cdd:cd03255  148 RVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDGKI 218

SapD

COG4170

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

35-328

1.48e-58

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 192.43 E-value: 1.48e-58

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP----ITDGSVLYDGEDIRTIPDRELR----RRMQIVFQDPG 106
Cdd:COG4170   20 VKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKdnwhVTADRFRWNGIDLLKLSPRERRkiigREIAMIFQEPS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNPRMSV-----RSIVGEPLQVNRLAEGAELTQKVADVLDSVGLK--REHMNRFPHEFSGGQKQRLALARALSLDPEF 179
Cdd:COG4170  100 SCLDPSAKIgdqliEAIPSWTFKGKWWQRFKWRKKRAIELLHRVGIKdhKDIMNSYPHELTEGECQKVMIAMAIANQPRL 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 180 ILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALM 259
Cdd:COG4170  180 LIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKSPHHPYTKALL 259

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 260 SAIPEPSLEKASRERIV-LSGDVPSPANPPPGCRFHTRCPIAvEGVCdVVDPPLETIdfDDHAVACHFPL 328
Cdd:COG4170  260 RSMPDFRQPLPHKSRLNtLPGSIPPLQHLPIGCRLGPRCPYA-QKKC-VETPRLRKI--KGHEFACHFPL 325

ABC_PstB_phosphate_transporter

cd03260

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...

12-243

5.01e-58

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).

Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 187.39 E-value: 5.01e-58

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFpikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPI-----TDGSVLYDGEDI 86
Cdd:cd03260    1 IELRDLNVYY---GD--------KHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDI 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  87 RTIPDR--ELRRRMQIVFQDPggsmNP-RMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNR-FPHEFSGG 162
Cdd:cd03260   70 YDLDVDvlELRRRVGMVFQKP----NPfPGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKDRlHALGLSGG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 163 QKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlgLTFVFITHALNVVNHISDRVAVMYLGKIVEIAN 242
Cdd:cd03260  146 QQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGP 223


                 .
gi 663511184 243 T 243
Cdd:cd03260  224 T 224

ABC_cobalt_CbiO_domain1

cd03225

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...

37-236

1.18e-57

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 186.13 E-value: 1.18e-57

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggsmnPRMSVR 116
Cdd:cd03225   16 ALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLVFQNP-----DDQFFG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGEPL---QVNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:cd03225   91 PTVEEEVafgLENLGLPEEEIEERVEEALELVGLE-GLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAG 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 663511184 194 QAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGK 236
Cdd:cd03225  170 RRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211

CcmA

COG1131

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

12-246

1.80e-57

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 186.42 E-value: 1.80e-57

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFpikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPd 91
Cdd:COG1131    1 IEVRGLTKRY---GD--------KTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDP- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 RELRRRMQIVFQDPGgsMNPRMSVR-------SIVGEPlqvnrlaeGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQK 164
Cdd:COG1131   69 AEVRRRIGYVPQEPA--LYPDLTVRenlrffaRLYGLP--------RKEARERIDELLELFGLT-DAADRKVGTLSGGMK 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 165 QRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTA 244
Cdd:COG1131  138 QRLGLALALLHDPELLILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPD 216


                 ..
gi 663511184 245 DL 246
Cdd:COG1131  217 EL 218

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

36-264

2.37e-57

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 194.54 E-value: 2.37e-57

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP-----ITDGSVLYDGEDIRTIPDRELRR----RMQIVFQDPG 106
Cdd:PRK15134  23 TVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPsppvvYPSGDIRFHGESLLHASEQTLRGvrgnKIAMIFQEPM 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLK--REHMNRFPHEFSGGQKQRLALARALSLDPEFILLDE 184
Cdd:PRK15134 103 VSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRqaAKRLTDYPHQLSGGERQRVMIAMALLTRPELLIADE 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 185 PTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALMSAIPE 264
Cdd:PRK15134 183 PTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPTHPYTQKLLNSEPS 262

ABC_NrtD_SsuB_transporters

cd03293

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...

12-232

1.25e-56

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 183.83 E-value: 1.25e-56

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIKGGmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRtipd 91
Cdd:cd03293    1 LEVRNVSKTYGGGGG-------AVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVT---- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 rELRRRMQIVFQDPggSMNPRMSVRSIVGEPLQVNRLAeGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALAR 171
Cdd:cd03293   70 -GPGPDRGYVFQQD--ALLPWLTVLDNVALGLELQGVP-KAEARERAEELLELVGLS-GFENAYPHQLSGGMRQRVALAR 144

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 663511184 172 ALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVM 232
Cdd:cd03293  145 ALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205

ABC_Pro_Gly_Betaine

cd03294

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...

37-254

8.78e-56

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 183.23 E-value: 8.78e-56

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDREL----RRRMQIVFQDPGgsMNPR 112
Cdd:cd03294   39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELrelrRKKISMVFQSFA--LLPH 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 MSVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLK-REHmnRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:cd03294  117 RTVLENVAFGLEVQGVPR-AEREERAAEALELVGLEgWEH--KYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDP 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184 192 SVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPY 254
Cdd:cd03294  194 LIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDY 256

ABC_Class3

cd03229

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...

12-236

2.02e-55

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 179.31 E-value: 2.02e-55

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD 91
Cdd:cd03229    1 LELKNVSKRYG-----------QKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLED 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 --RELRRRMQIVFQDPGgsMNPRMSVRSIVGEPLqvnrlaegaeltqkvadvldsvglkrehmnrfphefSGGQKQRLAL 169
Cdd:cd03229   70 elPPLRRRIGMVFQDFA--LFPHLTVLENIALGL------------------------------------SGGQQQRVAL 111

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 170 ARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGK 236
Cdd:cd03229  112 ARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178

MalK

COG3839

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...

35-252

5.47e-55

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];

Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 183.74 E-value: 5.47e-55

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElrRRMQIVFQDPGgsMNPRMS 114
Cdd:COG3839   16 VEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKD--RNIAMVFQSYA--LYPHMT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:COG3839   92 VYENIAFPLKLRKVPK-AEIDRRVREAAELLGL-EDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLR 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184 195 AQVLNLLEEIQEKLGLTFVFITH----ALNvvnhISDRVAVMYLGKIVEIANTADLFDKPAH 252
Cdd:COG3839  170 VEMRAEIKRLHRRLGTTTIYVTHdqveAMT----LADRIAVMNDGRIQQVGTPEELYDRPAN 227

CysA

COG1118

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...

12-259

8.98e-55

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 183.04 E-value: 8.98e-55

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRT-IP 90
Cdd:COG1118    3 IEVRNISKRFG-----------SFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFTnLP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DRElrRRMQIVFQDPGgsMNPRMSVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLAL 169
Cdd:COG1118   72 PRE--RRVGFVFQHYA--LFPHMTVAENIAFGLRVRPPSK-AEIRARVEELLELVQL--EGLaDRYPSQLSGGQRQRVAL 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 170 ARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITH----ALNVvnhiSDRVAVMYLGKIVEIANTAD 245
Cdd:COG1118  145 ARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHdqeeALEL----ADRVVVMNQGRIEQVGTPDE 220

                        250
                 ....*....|....
gi 663511184 246 LFDKPAHPYTHALM 259
Cdd:COG1118  221 VYDRPATPFVARFL 234

FepC

COG1120

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...

38-256

2.61e-54

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];

Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 178.70 E-value: 2.61e-54

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggSMNPRMSVRS 117
Cdd:COG1120   17 LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYVPQEP--PAPFGLTVRE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 118 IVG---EPLQVNRLAEGAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:COG1120   95 LVAlgrYPHLGLFGRPSAEDREAVEEALERTGL--EHLaDRPVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLDLAH 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184 194 QAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIV------EI---ANTADLFDKPAHPYTH 256
Cdd:COG1120  173 QLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVaqgppeEVltpELLEEVYGVEARVIED 244

ABC_OpuCA_Osmoprotection

cd03295

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...

37-254

2.54e-53

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 175.95 E-value: 2.54e-53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGgsMNPRMSVR 116
Cdd:cd03295   16 AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRRKIGYVIQQIG--LFPHMTVE 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGEPLQVNRLAEgAELTQKVADVLDSVGLK-REHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:cd03295   94 ENIALVPKLLKWPK-EKIRERADELLALVGLDpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDPITRD 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 196 QVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPY 254
Cdd:cd03295  173 QLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDF 231

PstB

COG1117

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...

1-255

1.17e-52

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 174.84 E-value: 1.17e-52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   1 MTEESRDGKVLIEVKGMKKWFpikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVL---LGLIPI--T 75
Cdd:COG1117    1 MTAPASTLEPKIEVRNLNVYY---GD--------KQALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmNDLIPGarV 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  76 DGSVLYDGEDI--RTIPDRELRRRMQIVFQDPggsmNP-RMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKRE-- 150
Cdd:COG1117   70 EGEILLDGEDIydPDVDVVELRRRVGMVFQKP----NPfPKSIYDNVAYGLRLHGIKSKSELDEIVEESLRKAALWDEvk 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 151 -HMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD-VSVqAQVLNLLEEIQEKlgLTFVFITHALNVVNHISDR 228
Cdd:COG1117  146 dRLKKSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDpIST-AKIEELILELKKD--YTIVIVTHNMQQAARVSDY 222

                        250       260
                 ....*....|....*....|....*..
gi 663511184 229 VAVMYLGKIVEIANTADLFDKPAHPYT 255
Cdd:COG1117  223 TAFFYLGELVEFGPTEQIFTNPKDKRT 249

ABC_CysA_sulfate_importer

cd03296

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...

12-254

1.77e-52

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 173.68 E-value: 1.77e-52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD 91
Cdd:cd03296    3 IEVRNVSKRFG-----------DFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPV 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 RElrRRMQIVFQDPggSMNPRMSVRSIVGEPLQVNRLAEG---AELTQKVADVLDSVGLKReHMNRFPHEFSGGQKQRLA 168
Cdd:cd03296   72 QE--RNVGFVFQHY--ALFRHMTVFDNVAFGLRVKPRSERppeAEIRAKVHELLKLVQLDW-LADRYPAQLSGGQRQRVA 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 169 LARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITH----ALNVvnhiSDRVAVMYLGKIVEIANTA 244
Cdd:cd03296  147 LARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHdqeeALEV----ADRVVVMNKGRIEQVGTPD 222

                        250
                 ....*....|
gi 663511184 245 DLFDKPAHPY 254
Cdd:cd03296  223 EVYDHPASPF 232

FtsE

COG2884

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

37-239

9.59e-51

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 168.69 E-value: 9.59e-51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRE---LRRRMQIVFQDpgGSMNPRM 113
Cdd:COG2884   17 ALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREipyLRRRIGVVFQD--FRLLPDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:COG2884   95 TVYENVALPLRVTGKSR-KEIRRRVREVLDLVGLS-DKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTGNLDPET 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 663511184 194 QAQVLNLLEEIQeKLGLTFVFITHALNVVNHISDRVAVMYLGKIVE 239
Cdd:COG2884  173 SWEIMELLEEIN-RRGTTVLIATHDLELVDRMPKRVLELEDGRLVR 217

PRK15093

peptide ABC transporter ATP-binding protein SapD;

35-328

2.21e-50

peptide ABC transporter ATP-binding protein SapD;

Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 171.14 E-value: 2.21e-50

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGL----IPITDGSVLYDGEDIRTIPDRELRR----RMQIVFQDPG 106
Cdd:PRK15093  20 VKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVtkdnWRVTADRMRFDDIDLLRLSPRERRKlvghNVSMIFQEPQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNP-----RMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLK--REHMNRFPHEFSGGQKQRLALARALSLDPEF 179
Cdd:PRK15093 100 SCLDPservgRQLMQNIPGWTYKGRWWQRFGWRKRRAIELLHRVGIKdhKDAMRSFPYELTEGECQKVMIAIALANQPRL 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 180 ILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALM 259
Cdd:PRK15093 180 LIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTPHHPYTQALI 259

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 260 SAIPEPSLEKASRERI-VLSGDVPSPANPPPGCRFHTRCPIAvEGVCdVVDPPLETIdfDDHAVACHFPL 328
Cdd:PRK15093 260 RAIPDFGSAMPHKSRLnTLPGAIPLLEHLPIGCRLGPRCPYA-QREC-IETPRLTGA--KNHLYACHFPL 325

NatA

COG4555

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...

11-249

7.53e-50

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];

Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 166.96 E-value: 7.53e-50

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:COG4555    1 MIEVENLSKKYG-----------KVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEP 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 dRELRRRMQIVFQDPGGSmnPRMSVRSIVGEPLQVNRLAeGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALA 170
Cdd:COG4555   70 -REARRQIGVLPDERGLY--DRLTVRENIRYFAELYGLF-DEELKKRIEELIELLGL-EEFLDRRVGELSTGMKKKVALA 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 171 RALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQeKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDK 249
Cdd:COG4555  145 RALVHDPKVLLLDEPTNGLDVMARRLLREILRALK-KEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREE 222

phnK

PRK11701

phosphonate C-P lyase system protein PhnK; Provisional

36-262

8.12e-49

phosphonate C-P lyase system protein PhnK; Provisional

Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 164.71 E-value: 8.12e-49

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE-----DIRTIPDRELRRRMQ----IVFQDPG 106
Cdd:PRK11701  20 KGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRdgqlrDLYALSEAERRRLLRtewgFVHQHPR 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNPRMSVRSIVGEPLqvnrLAEGA----ELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILL 182
Cdd:PRK11701 100 DGLRMQVSAGGNIGERL----MAVGArhygDIRATAGDWLERVEIDAARIDDLPTTFSGGMQQRLQIARNLVTHPRLVFM 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 183 DEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALMSAI 262
Cdd:PRK11701 176 DEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLTDQVLDDPQHPYTQLLVSSV 255

PRK10261

glutathione transporter ATP-binding protein; Provisional

35-264

1.15e-48

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 173.12 E-value: 1.15e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE----------DIRTIPDRELRR----RMQI 100
Cdd:PRK10261  29 IAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMllrrrsrqviELSEQSAAQMRHvrgaDMAM 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 101 VFQDPGGSMNPRMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHM--NRFPHEFSGGQKQRLALARALSLDPE 178
Cdd:PRK10261 109 IFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTilSRYPHQLSGGMRQRVMIAMALSCRPA 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 179 FILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHAL 258
Cdd:PRK10261 189 VLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHPYTRAL 268


                 ....*.
gi 663511184 259 MSAIPE 264
Cdd:PRK10261 269 LAAVPQ 274

FetA

COG4619

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

39-237

1.54e-48

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 162.29 E-value: 1.54e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGgsMnPRMSVRSI 118
Cdd:COG4619   17 SPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEWRRQVAYVPQEPA--L-WGGTVRDN 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 119 VGEPLQvnrLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVL 198
Cdd:COG4619   94 LPFPFQ---LRERKFDRERALELLERLGLPPDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPENTRRVE 170

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 663511184 199 NLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:COG4619  171 ELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209

ABC_ATPase

cd00267

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...

28-236

3.23e-48

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 159.72 E-value: 3.23e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  28 LSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQdpgg 107
Cdd:cd00267    5 LSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGYVPQ---- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 108 smnprmsvrsivgeplqvnrlaegaeltqkvadvldsvglkrehmnrfpheFSGGQKQRLALARALSLDPEFILLDEPTS 187
Cdd:cd00267   81 ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 663511184 188 ALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGK 236
Cdd:cd00267  110 GLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157

ABC_DR_subfamily_A

cd03230

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...

12-237

4.82e-48

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 159.87 E-value: 4.82e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPd 91
Cdd:cd03230    1 IEVRNLSKRYG-----------KKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEP- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 RELRRRMQIVFQDPggSMNPRMSVRsivgeplqvnrlaegaeltqkvadvldsvglkrEHMnrfphEFSGGQKQRLALAR 171
Cdd:cd03230   69 EEVKRRIGYLPEEP--SLYENLTVR---------------------------------ENL-----KLSGGMKQRLALAQ 108

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 172 ALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:cd03230  109 ALLHDPELLILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173

SunT

COG2274

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...

37-254

7.76e-48

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];

Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 171.56 E-value: 7.76e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSM--NP 111
Cdd:COG2274  490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLRRQIGVVLQDVflfSGTIreNI 569

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 RMSVRSIvgEPLQVNRLAEGAELTQKVadvldsvglkrehmNRFPH-----------EFSGGQKQRLALARALSLDPEFI 180
Cdd:COG2274  570 TLGDPDA--TDEEIIEAARLAGLHDFI--------------EALPMgydtvvgeggsNLSGGQRQRLAIARALLRNPRIL 633

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663511184 181 LLDEPTSALDVSVQAQVLNLLEEIqeKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKPAHPY 254
Cdd:COG2274  634 ILDEATSALDAETEAIILENLRRL--LKGRTVIIIAHRLSTIRL-ADRIIVLDKGRIVEDGTHEELLARKGLYA 704

PhnC

COG3638

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...

11-262

8.46e-48

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 161.76 E-value: 8.46e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:COG3638    2 MLELRNLSKRYP--GG--------TPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALR 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DREL---RRRMQIVFQDPGgsMNPRMSV---------------RSIVGeplqvnRLAEgaELTQKVADVLDSVGLKrEHM 152
Cdd:COG3638   72 GRALrrlRRRIGMIFQQFN--LVPRLSVltnvlagrlgrtstwRSLLG------LFPP--EDRERALEALERVGLA-DKA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 153 NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVM 232
Cdd:COG3638  141 YQRADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGL 220

                        250       260       270
                 ....*....|....*....|....*....|
gi 663511184 233 YLGKIVeiantadlFDKPAHPYTHALMSAI 262
Cdd:COG3638  221 RDGRVV--------FDGPPAELTDAVLREI 242

ABC_MalK_N

cd03301

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...

35-241

7.22e-47

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.

Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 158.19 E-value: 7.22e-47

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElrRRMQIVFQDPggSMNPRMS 114
Cdd:cd03301   13 VTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKD--RDIAMVFQNY--ALYPHMT 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:cd03301   89 VYDNIAFGLKLRKVPK-DEIDERVREVAELLQIE-HLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLR 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 663511184 195 AQVLNLLEEIQEKLGLTFVFITH----ALNvvnhISDRVAVMYLGKIVEIA 241
Cdd:cd03301  167 VQMRAELKRLQQRLGTTTIYVTHdqveAMT----MADRIAVMNDGQIQQIG 213

ABCC_MRP_Like

cd03228

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...

37-236

1.71e-46

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 156.00 E-value: 1.71e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSmnprm 113
Cdd:cd03228   17 VLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKNIAYVPQDPflfSGT----- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 svrsivgeplqvnrlaegaeltqkVADVLdsvglkrehmnrfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:cd03228   92 ------------------------IRENI----------------LSGGQRQRIAIARALLRDPPILILDEATSALDPET 131

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 663511184 194 QAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGK 236
Cdd:cd03228  132 EALILEALRALAK--GKTVIVIAHRLSTIRD-ADRIIVLDDGR 171

nikD

PRK10418

nickel transporter ATP-binding protein NikD; Provisional

38-261

1.87e-46

nickel transporter ATP-binding protein NikD; Provisional

Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 158.71 E-value: 1.87e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP----ITDGSVLYDGEDIRTipdRELR-RRMQIVFQDPGGSMNPR 112
Cdd:PRK10418  19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPagvrQTAGRVLLDGKPVAP---CALRgRKIATIMQNPRSAFNPL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 MSVRSIVGEPL-QVNRLAEGAELtqkvADVLDSVGLKREH--MNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSAL 189
Cdd:PRK10418  96 HTMHTHARETClALGKPADDATL----TAALEAVGLENAArvLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDL 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184 190 DVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALMSA 261
Cdd:PRK10418 172 DVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVSA 243

LivG

COG0411

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...

8-238

2.28e-46

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];

Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 158.28 E-value: 2.28e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   8 GKVLIEVKGMKKWFpikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIR 87
Cdd:COG0411    1 SDPLLEVRGLTKRF---GG--------LVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDIT 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  88 TIPDRElRRRMQIV--FQDPggSMNPRMSVR-------------SIVGEPLQVNR-LAEGAELTQKVADVLDSVGLkREH 151
Cdd:COG0411   70 GLPPHR-IARLGIArtFQNP--RLFPELTVLenvlvaaharlgrGLLAALLRLPRaRREEREARERAEELLERVGL-ADR 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 152 MNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAV 231
Cdd:COG0411  146 ADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVV 225


                 ....*..
gi 663511184 232 MYLGKIV 238
Cdd:COG0411  226 LDFGRVI 232

potA

PRK09452

spermidine/putrescine ABC transporter ATP-binding protein PotA;

1-255

4.62e-46

spermidine/putrescine ABC transporter ATP-binding protein PotA;

Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 160.88 E-value: 4.62e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   1 MTEESRDGKVLIEVKGMKKWFPIKggmlsevkihvRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVL 80
Cdd:PRK09452   4 LNKQPSSLSPLVELRGISKSFDGK-----------EVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIM 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  81 YDGEDIRTIPDRelRRRMQIVFQDPggSMNPRMSVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLkrEHM-NRFPHEF 159
Cdd:PRK09452  73 LDGQDITHVPAE--NRHVNTVFQSY--ALFPHMTVFENVAFGLRMQKTPA-AEITPRVMEALRMVQL--EEFaQRKPHQL 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 160 SGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITH----ALNvvnhISDRVAVMYLG 235
Cdd:PRK09452 146 SGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHdqeeALT----MSDRIVVMRDG 221

                        250       260
                 ....*....|....*....|
gi 663511184 236 KIVEIANTADLFDKPAHPYT 255
Cdd:PRK09452 222 RIEQDGTPREIYEEPKNLFV 241

ABC_HisP_GlnQ

cd03262

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...

12-237

7.34e-46

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.

Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 155.77 E-value: 7.34e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIKggmlsevkiHVraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrTIPD 91
Cdd:cd03262    1 IEIKNLHKSFGDF---------HV--LKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKL-TDDK 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 R---ELRRRMQIVFQdpggSMN--PRMSV-RSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQ 165
Cdd:cd03262   69 KninELRQKVGMVFQ----QFNlfPHLTVlENITLAPIKVKGMSK-AEAEERALELLEKVGLA-DKADAYPAQLSGGQQQ 142

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184 166 RLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:cd03262  143 RVAIARALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGRI 213

ABC_Iron-Siderophores_B12_Hemin

cd03214

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...

36-238

1.01e-45

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.

Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 154.13 E-value: 1.01e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQdpggsmnprmsv 115
Cdd:cd03214   13 TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVPQ------------ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 rsivgeplqvnrlaegaeltqkvadVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:cd03214   81 -------------------------ALELLGL--AHLaDRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQ 133

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 663511184 195 AQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03214  134 IELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIV 177

ECF_ATPase_1

TIGR04520

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...

34-247

1.74e-45

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 156.44 E-value: 1.74e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTiPDR--ELRRRMQIVFQDPGGSMnp 111
Cdd:TIGR04520  14 EKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLD-EENlwEIRKKVGMVFQNPDNQF-- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  112 rmsVRSIVG-------EPLQVNRlaegAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDE 184
Cdd:TIGR04520  91 ---VGATVEddvafglENLGVPR----EEMRKRVDEALKLVGME-DFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILDE 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663511184  185 PTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALN-VVNhiSDRVAVMYLGKIVEIANTADLF 247
Cdd:TIGR04520 163 ATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEeAVL--ADRVIVMNKGKIVAEGTPREIF 224

ABC_PhnC_transporter

cd03256

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...

12-251

4.16e-45

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 154.65 E-value: 4.16e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD 91
Cdd:cd03256    1 IEVENLSKTYP--NG--------KKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKG 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 REL---RRRMQIVFQDPGgsMNPRMSVrsivGEPLQVNRLAE-----------GAELTQKVADVLDSVGLkREHMNRFPH 157
Cdd:cd03256   71 KALrqlRRQIGMIFQQFN--LIERLSV----LENVLSGRLGRrstwrslfglfPKEEKQRALAALERVGL-LDKAYQRAD 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 158 EFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:cd03256  144 QLSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRI 223

                        250
                 ....*....|....
gi 663511184 238 VeiantadlFDKPA 251
Cdd:cd03256  224 V--------FDGPP 229

ECF_ATPase_2

TIGR04521

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...

36-250

4.25e-45

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 155.69 E-value: 4.25e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD---RELRRRMQIVFQDPG------ 106
Cdd:TIGR04521  19 KALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKkklKDLRKKVGLVFQFPEhqlfee 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  107 --------GSMNPRMSvrsivgeplqvnrlaeGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPE 178
Cdd:TIGR04521  99 tvykdiafGPKNLGLS----------------EEEAEERVKEALELVGLDEEYLERSPFELSGGQMRRVAIAGVLAMEPE 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184  179 FILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:TIGR04521 163 VLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV 234

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

38-187

5.17e-45

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 151.26 E-value: 5.17e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggSMNPRMSVRS 117
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDP--QLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184  118 IVGEPLQVNRLAEgAELTQKVADVLDSVGLK---REHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTS 187
Cdd:pfam00005  79 NLRLGLLLKGLSK-REKDARAEEALEKLGLGdlaDRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

potA

TIGR01187

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...

53-288

1.01e-44

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 156.11 E-value: 1.01e-44

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   53 IVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRelRRRMQIVFQDPggSMNPRMSVRSIVGEPLQVNRLAEgA 132
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPH--LRHINMVFQSY--ALFPHMTVEENVAFGLKMRKVPR-A 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  133 ELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTF 212
Cdd:TIGR01187  76 EIKPRVLEALRLVQLE-EFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITF 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  213 VFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALM--SAIPEPSLEKASRERIVLSG----------D 280
Cdd:TIGR01187 155 VFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIgeINVFEATVIERKSEQVVLAGvegrrcdiytD 234


                  ....*...
gi 663511184  281 VPSPANPP 288
Cdd:TIGR01187 235 VPVEKDQP 242

PRK14247

phosphate ABC transporter ATP-binding protein; Provisional

35-255

1.14e-44

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 153.92 E-value: 1.14e-44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLI-----PITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSm 109
Cdd:PRK14247  16 VEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIelypeARVSGEVYLDGQDIFKMDVIELRRRVQMVFQIPNPI- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 110 nPRMSVRSIVGEPLQVNRLAEG-AELTQKVADVLDSVGLKREHMNRF---PHEFSGGQKQRLALARALSLDPEFILLDEP 185
Cdd:PRK14247  95 -PNLSIFENVALGLKLNRLVKSkKELQERVRWALEKAQLWDEVKDRLdapAGKLSGGQQQRLCIARALAFQPEVLLADEP 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 186 TSALDVSVQAQVLNLLEEIQEKlgLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYT 255
Cdd:PRK14247 174 TANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHELT 241

ABC_Mj1267_LivG_branched

cd03219

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...

12-238

1.21e-44

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).

Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 153.36 E-value: 1.21e-44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFpikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD 91
Cdd:cd03219    1 LEVRGLTKRF---GG--------LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPP 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 RElRRRMQIV--FQDPG--GSM----NPRMSVRSIVGEP-LQVNRLAEGAELTQKVADVLDSVGLkREHMNRFPHEFSGG 162
Cdd:cd03219   70 HE-IARLGIGrtFQIPRlfPELtvleNVMVAAQARTGSGlLLARARREEREARERAEELLERVGL-ADLADRPAGELSYG 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 163 QKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03219  148 QQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRER-GITVLLVEHDMDVVMSLADRVTVLDQGRVI 222

ABC_ModC_like

cd03299

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...

38-250

7.56e-43

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 148.64 E-value: 7.56e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRelRRRMQIVFQDPggSMNPRMSVRS 117
Cdd:cd03299   15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPE--KRDISYVPQNY--ALFPHMTVYK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 118 IVGEPLQvNRLAEGAELTQKVADVLDSVGLkrEH-MNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQ 196
Cdd:cd03299   91 NIAYGLK-KRKVDKKEIERKVLEIAEMLGI--DHlLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEK 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 663511184 197 VLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:cd03299  168 LREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKP 221

glnQ

PRK09493

glutamine ABC transporter ATP-binding protein GlnQ;

34-253

1.27e-42

glutamine ABC transporter ATP-binding protein GlnQ;

Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 148.32 E-value: 1.27e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIR--TIPDRELRRRMQIVFQDpgGSMNP 111
Cdd:PRK09493  13 PTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpKVDERLIRQEAGMVFQQ--FYLFP 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 RMS-VRSIVGEPLQVnRLAEGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:PRK09493  91 HLTaLENVMFGPLRV-RGASKEEAEKQARELLAKVGL-AERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALD 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184 191 VSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHP 253
Cdd:PRK09493 169 PELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQ 230

CydD

COG4988

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...

36-246

3.68e-42

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 154.15 E-value: 3.68e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP----Ggsmnp 111
Cdd:COG4988  351 PALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRRQIAWVPQNPylfaG----- 425

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 rmSVRSIVgeplqvnRLAE-GAELTQkVADVLDSVGLkREHMNRFPHEF-----------SGGQKQRLALARALSLDPEF 179
Cdd:COG4988  426 --TIRENL-------RLGRpDASDEE-LEAALEAAGL-DEFVAALPDGLdtplgeggrglSGGQAQRLALARALLRDAPL 494

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 180 ILLDEPTSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADL 246
Cdd:COG4988  495 LLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRLALLAQ-ADRILVLDDGRIVEQGTHEEL 558

ThiQ

COG3840

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

42-253

4.75e-42

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 146.44 E-value: 4.75e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  42 DLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElrRRMQIVFQDpggsmN---PRMSVRSI 118
Cdd:COG3840   19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAE--RPVSMLFQE-----NnlfPHLTVAQN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 119 VGEPLQVN-RLaeGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQV 197
Cdd:COG3840   92 IGLGLRPGlKL--TAEQRAQVEQALERVGLA-GLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPALRQEM 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 198 LNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHP 253
Cdd:COG3840  169 LDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPP 224

MdlB

COG1132

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

37-240

8.53e-42

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 153.40 E-value: 8.53e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP----Ggsmnpr 112
Cdd:COG1132  355 VLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQIGVVPQDTflfsG------ 428

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 mSVRSivgeplqvN-RL----AEGAELTQ--KVADVLDSVglkrehmNRFPH-----------EFSGGQKQRLALARALS 174
Cdd:COG1132  429 -TIRE--------NiRYgrpdATDEEVEEaaKAAQAHEFI-------EALPDgydtvvgergvNLSGGQRQRIAIARALL 492

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 175 LDPEFILLDEPTSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVEI 240
Cdd:COG1132  493 KDPPILILDEATSALDTETEALIQEALERLMK--GRTTIVIAHRLSTIRN-ADRILVLDDGRIVEQ 555

ABC_DrrA

cd03265

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...

12-246

9.50e-42

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 145.21 E-value: 9.50e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFpikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPd 91
Cdd:cd03265    1 IEVENLVKKY---GD--------FEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREP- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 RELRRRMQIVFQDPggSMNPRMSVRsivgEPLQVN-RLA--EGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLA 168
Cdd:cd03265   69 REVRRRIGIVFQDL--SVDDELTGW----ENLYIHaRLYgvPGAERRERIDELLDFVGLL-EAADRLVKTYSGGMRRRLE 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 169 LARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADL 246
Cdd:cd03265  142 IARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219

ABC_Carb_Monos_I

cd03216

First domain of the ATP-binding cassette component of monosaccharide transport system; This ...

12-238

2.81e-41

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 142.18 E-value: 2.81e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTI-P 90
Cdd:cd03216    1 LELRGITKRFG-----------GVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFAsP 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DRELRRRMQIVFQdpggsmnprmsvrsivgeplqvnrlaegaeltqkvadvldsvglkrehmnrfpheFSGGQKQRLALA 170
Cdd:cd03216   70 RDARRAGIAMVYQ-------------------------------------------------------LSVGERQMVEIA 94

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 171 RALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03216   95 RALARNARLLILDEPTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVV 161

fbpC

PRK11432

ferric ABC transporter ATP-binding protein;

38-251

8.65e-41

ferric ABC transporter ATP-binding protein;

Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 146.40 E-value: 8.65e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDI--RTIPDRELrrrmQIVFQDPggSMNPRMSV 115
Cdd:PRK11432  22 IDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVthRSIQQRDI----CMVFQSY--ALFPHMSL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:PRK11432  96 GENVGYGLKMLGVPK-EERKQRVKEALELVDLA-GFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRR 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 196 QVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPA 251
Cdd:PRK11432 174 SMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPA 229

CydC

COG4987

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...

37-254

1.82e-40

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 149.53 E-value: 1.82e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSmnprm 113
Cdd:COG4987  350 VLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRRIAVVPQRPhlfDTT----- 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 svrsiVGEPLqvnRLAEGAELTQKVADVLDSVGLkREHMNRFPH-----------EFSGGQKQRLALARALSLDPEFILL 182
Cdd:COG4987  425 -----LRENL---RLARPDATDEELWAALERVGL-GDWLAALPDgldtwlgeggrRLSGGERRRLALARALLRDAPILLL 495

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184 183 DEPTSALDVSVQAQVLNLLEEI-QEKlglTFVFITHALNVVNHIsDRVAVMYLGKIVEIANTADLFDKPAHPY 254
Cdd:COG4987  496 DEPTEGLDAATEQALLADLLEAlAGR---TVLLITHRLAGLERM-DRILVLEDGRIVEQGTHEELLAQNGRYR 564

ZnuC

COG1121

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...

34-257

5.87e-40

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 141.38 E-value: 5.87e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRtipdrelRRRMQI--VFQDpgGSMNP 111
Cdd:COG1121   18 GRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPR-------RARRRIgyVPQR--AEVDW 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 R--MSVRSIVGeplqVNRLAE-------GAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILL 182
Cdd:COG1121   89 DfpITVRDVVL----MGRYGRrglfrrpSRADREAVDEALERVGL-EDLADRPIGELSGGQQQRVLLARALAQDPDLLLL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 183 DEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVM-----YLGKIVEI---ANTADLFDKPAHPY 254
Cdd:COG1121  164 DEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLLnrglvAHGPPEEVltpENLSRAYGGPVALL 242


                 ...
gi 663511184 255 THA 257
Cdd:COG1121  243 AHG 245

ABC_ModC_molybdenum_transporter

cd03297

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...

41-241

6.48e-40

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 140.12 E-value: 6.48e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKrGETLGIVGESGCGKTTLGRVLLGLIPIT------DGSVLYDGEDIRTIPDRelRRRMQIVFQDpgGSMNPRMS 114
Cdd:cd03297   17 IDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDggtivlNGTVLFDSRKKINLPPQ--QRKIGLVFQQ--YALFPHLN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVNRlaeGAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:cd03297   92 VRENLAFGLKRKR---NREDRISVDELLDLLGL--DHLlNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRAL 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 663511184 194 QAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIA 241
Cdd:cd03297  167 RLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214

ABC_phnC

TIGR02315

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...

11-262

1.52e-39

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]

Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 140.13 E-value: 1.52e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   11 LIEVKGMKKWFPikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:TIGR02315   1 MLEVENLSKVYP--NG--------KQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLR 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   91 DREL---RRRMQIVFQDpggsMN--PRMSVRsivgEPLQVNRLA------------EGAElTQKVADVLDSVGLKREHMN 153
Cdd:TIGR02315  71 GKKLrklRRRIGMIFQH----YNliERLTVL----ENVLHGRLGykptwrsllgrfSEED-KERALSALERVGLADKAYQ 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  154 RfPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMY 233
Cdd:TIGR02315 142 R-ADQLSGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLK 220

                         250       260
                  ....*....|....*....|....*....
gi 663511184  234 LGKIVeiantadlFDKPAHPYTHALMSAI 262
Cdd:TIGR02315 221 AGEIV--------FDGAPSELDDEVLRHI 241

potG

PRK11607

putrescine ABC transporter ATP-binding subunit PotG;

37-255

1.54e-39

putrescine ABC transporter ATP-binding subunit PotG;

Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 143.82 E-value: 1.54e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPdrELRRRMQIVFQDPggSMNPRMSVR 116
Cdd:PRK11607  34 AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVP--PYQRPINMMFQSY--ALFPHMTVE 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQ 196
Cdd:PRK11607 110 QNIAFGLKQDKLPK-AEIASRVNEMLGLVHMQ-EFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDR 187

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 197 VLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYT 255
Cdd:PRK11607 188 MQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYS 246

ABC_NatA_sodium_exporter

cd03266

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...

11-238

2.76e-39

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.

Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 138.65 E-value: 2.76e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFpikggmlSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:cd03266    1 MITADALTKRF-------RDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 dRELRRRMQIVFQDPGgsMNPRMSVRSIVGEPLQVNRLaEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALA 170
Cdd:cd03266   74 -AEARRRLGFVSDSTG--LYDRLTARENLEYFAGLYGL-KGDELTARLEELADRLGME-ELLDRRVGGFSTGMRQKVAIA 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 171 RALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEkLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03266  149 RALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRA-LGKCILFSTHIMQEVERLCDRVVVLHRGRVV 215

ABC_cobalt_CbiO_domain2

cd03226

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...

36-238

7.62e-39

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 137.00 E-value: 7.62e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDirtIPDRELRRRMQIVFQDPGGSMNpRMSV 115
Cdd:cd03226   14 EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKP---IKAKERRKSIGYVMQDVDYQLF-TDSV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPLQvnRLAEGAELTQKVADVLDSVGLKREHmnrfPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:cd03226   90 REELLLGLK--ELDAGNEQAETVLKDLDLYALKERH----PLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNME 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 663511184 196 QVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03226  164 RVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAIV 205

PRK10851

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

12-251

8.47e-39

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 141.37 E-value: 8.47e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD 91
Cdd:PRK10851   3 IEIANIKKSFG-----------RTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHA 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 RElrRRMQIVFQDPggSMNPRMSVRSIVGEPLQV---NRLAEGAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRL 167
Cdd:PRK10851  72 RD--RKVGFVFQHY--ALFRHMTVFDNIAFGLTVlprRERPNAAAIKAKVTQLLEMVQL--AHLaDRYPAQLSGGQKQRV 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 168 ALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLF 247
Cdd:PRK10851 146 ALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVW 225


                 ....
gi 663511184 248 DKPA 251
Cdd:PRK10851 226 REPA 229

CcmA

COG4133

ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...

39-217

1.75e-38

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 136.07 E-value: 1.75e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDrELRRRMQIVFQDPGgsMNPRMSVRsi 118
Cdd:COG4133   19 SGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDARE-DYRRRLAYLGHADG--LKPELTVR-- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 119 vgEPLQ-VNRLAEGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQV 197
Cdd:COG4133   94 --ENLRfWAALYGLRADREAIDEALEAVGL-AGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALL 170

                        170       180
                 ....*....|....*....|
gi 663511184 198 LNLLEEIQEKlGLTFVFITH 217
Cdd:COG4133  171 AELIAAHLAR-GGAVLLTTH 189

YbbA

COG4181

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...

11-239

2.69e-38

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 136.41 E-value: 2.69e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPIKGGMLSevkihvrAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:COG4181    8 IIELRGLTKTVGTGAGELT-------ILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DREL----RRRMQIVFQdpggSMN--PRMSVRSIVGEPLQvnrLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQK 164
Cdd:COG4181   81 EDARarlrARHVGFVFQ----SFQllPTLTALENVMLPLE---LAGRRDARARARALLERVGLG-HRLDHYPAQLSGGEQ 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 165 QRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVE 239
Cdd:COG4181  153 QRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRAGRLVE 226

ABCC_Glucan_exporter_like

cd03254

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...

37-249

3.74e-38

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 136.20 E-value: 3.74e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPG---GSM--NP 111
Cdd:cd03254   18 VLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSMIGVVLQDTFlfsGTImeNI 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 RMSVRSIVGEplQVNRLAEGAELTQKVADVLDsvGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:cd03254   98 RLGRPNATDE--EVIEAAKEAGAHDFIMKLPN--GYD-TVLGENGGNLSQGERQLLAIARAMLRDPKILILDEATSNIDT 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 192 SVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDK 249
Cdd:cd03254  173 ETEKLIQEALEKLMK--GRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEGTHDELLAK 227

PRK10619

histidine ABC transporter ATP-binding protein HisP;

40-260

1.44e-37

histidine ABC transporter ATP-binding protein HisP;

Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 135.48 E-value: 1.44e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRE-------------LRRRMQIVFQDpg 106
Cdd:PRK10619  23 GVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDgqlkvadknqlrlLRTRLTMVFQH-- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNPRMSVRSIVGE-PLQVNRLAEgAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEP 185
Cdd:PRK10619 101 FNLWSHMTVLENVMEaPIQVLGLSK-QEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIARALAMEPEVLLFDEP 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 186 TSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALMS 260
Cdd:PRK10619 180 TSALDPELVGEVLRIMQQLAEE-GKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFLK 253

type_I_sec_LssB

TIGR03375

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...

37-238

1.77e-37

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]

Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 142.31 E-value: 1.77e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPG---GSM--NP 111
Cdd:TIGR03375 480 ALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADLRRNIGYVPQDPRlfyGTLrdNI 559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  112 RMSVRSIVGEplqvnRLAEGAELtqkvADVLDSVGLKREHMNRFPHE----FSGGQKQRLALARALSLDPEFILLDEPTS 187
Cdd:TIGR03375 560 ALGAPYADDE-----EILRAAEL----AGVTEFVRRHPDGLDMQIGErgrsLSGGQRQAVALARALLRDPPILLLDEPTS 630

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 663511184  188 ALDVSVQAQVL-NLLEEIQEKlglTFVFITH---ALNVVnhisDRVAVMYLGKIV 238
Cdd:TIGR03375 631 AMDNRSEERFKdRLKRWLAGK---TLVLVTHrtsLLDLV----DRIIVMDNGRIV 678

cbiO

PRK13635

energy-coupling factor ABC transporter ATP-binding protein;

37-247

2.13e-37

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 135.53 E-value: 2.13e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE--DIRTIPDreLRRRMQIVFQDPG----GSmn 110
Cdd:PRK13635  22 ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMvlSEETVWD--VRRQVGMVFQNPDnqfvGA-- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 111 prmSVRSIVGEPLQvNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:PRK13635  98 ---TVQDDVAFGLE-NIGVPREEMVERVDQALRQVGME-DFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLD 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 191 VSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLF 247
Cdd:PRK13635 173 PRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIF 228

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

9-246

2.24e-37

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 140.15 E-value: 2.24e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   9 KVLIEVKGMKKWFPikgGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRT 88
Cdd:COG1129    2 EPLLEMRGISKSFG---G--------VKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRF 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  89 IPDRE-LRRRMQIVFQDPggSMNPRMSV-------RSIVGEPLqVNRlaegAELTQKVADVLDSVGLkreHMNrfPH--- 157
Cdd:COG1129   71 RSPRDaQAAGIAIIHQEL--NLVPNLSVaeniflgREPRRGGL-IDW----RAMRRRARELLARLGL---DID--PDtpv 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 158 -EFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGK 236
Cdd:COG1129  139 gDLSVAQQQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVLRDGR 217

                        250
                 ....*....|
gi 663511184 237 IVEIANTADL 246
Cdd:COG1129  218 LVGTGPVAEL 227

ABC_FtsE

cd03292

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...

35-237

2.54e-37

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages

Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 133.30 E-value: 2.54e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRE---LRRRMQIVFQDpgGSMNP 111
Cdd:cd03292   14 TAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAipyLRRKIGVVFQD--FRLLP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 RMSVRSIVGEPLQVNRlAEGAELTQKVADVLDSVGLKREHmNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:cd03292   92 DRNVYENVAFALEVTG-VPPREIRKRVPAALELVGLSHKH-RALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDP 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 663511184 192 SVQAQVLNLLEEIQeKLGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:cd03292  170 DTTWEIMNLLKKIN-KAGTTVVVATHAKELVDTTRHRVIALERGKL 214

ABC_Metallic_Cations

cd03235

ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...

34-232

3.51e-37

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.

Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 133.04 E-value: 3.51e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEdirtiPDRELRRRMQIVFQDPGGSMNPRM 113
Cdd:cd03235   11 GHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGK-----PLEKERKRIGYVPQRRSIDRDFPI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSIVGEPLqVNRLAEGAELT----QKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSAL 189
Cdd:cd03235   86 SVRDVVLMGL-YGHKGLFRRLSkadkAKVDEALERVGLS-ELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGV 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 663511184 190 DVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVM 232
Cdd:cd03235  164 DPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLL 205

ABCC_bacteriocin_exporters

cd03245

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...

37-238

8.02e-37

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.

Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 132.33 E-value: 8.02e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPG---GSMNPRM 113
Cdd:cd03245   19 ALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIGYVPQDVTlfyGTLRDNI 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLK-REH-MNrfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:cd03245   99 TLGAPLADDERILRAAELAGVTDFVNKHPNGLDLQiGERgRG-----LSGGQRQAVALARALLNDPPILLLDEPTSAMDM 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 663511184 192 SVQAQVL-NLLEEIQEKlglTFVFITH---ALNVVnhisDRVAVMYLGKIV 238
Cdd:cd03245  174 NSEERLKeRLRQLLGDK---TLIIITHrpsLLDLV----DRIIVMDSGRIV 217

artP

PRK11124

arginine transporter ATP-binding subunit; Provisional

41-250

1.58e-36

arginine transporter ATP-binding subunit; Provisional

Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 132.06 E-value: 1.58e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLlGLIPITDGSVLY---DGEDIRTIPD----RELRRRMQIVFQDPggSMNPRM 113
Cdd:PRK11124  21 ITLDCPQGETLVLLGPSGAGKSSLLRVL-NLLEMPRSGTLNiagNHFDFSKTPSdkaiRELRRNVGMVFQQY--NLWPHL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVR-SIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:PRK11124  98 TVQqNLIEAPCRVLGLSK-DQALARAEKLLERLRLK-PYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPE 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 193 VQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIAnTADLFDKP 250
Cdd:PRK11124 176 ITAQIVSIIRELAET-GITQVIVTHEVEVARKTASRVVYMENGHIVEQG-DASCFTQP 231

ABC_MTABC3_MDL1_MDL2

cd03249

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...

34-254

1.58e-36

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.

Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 131.89 E-value: 1.58e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSM- 109
Cdd:cd03249   15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQIGLVSQEPvlfDGTIa 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 110 -NPRMSVRS-IVGEPLQVNRLAEGAELTQKVADVLDS-VGlkrehmnrfPH--EFSGGQKQRLALARALSLDPEFILLDE 184
Cdd:cd03249   95 eNIRYGKPDaTDEEVEEAAKKANIHDFIMSLPDGYDTlVG---------ERgsQLSGGQKQRIAIARALLRNPKILLLDE 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 185 PTSALDVSVQAQVLNLLEEIqeKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKPAHPY 254
Cdd:cd03249  166 ATSALDAESEKLVQEALDRA--MKGRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGTHDELMAQKGVYA 232

cbiO

PRK13637

energy-coupling factor transporter ATPase;

36-247

1.70e-36

energy-coupling factor transporter ATPase;

Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 133.25 E-value: 1.70e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDI--RTIPDRELRRRMQIVFQDPGGSMNPRM 113
Cdd:PRK13637  21 KALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDItdKKVKLSDIRKKVGLVFQYPEYQLFEET 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSIVGEPlqVNRLAEGAELTQKVADVLDSVGLKREHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:PRK13637 101 IEKDIAFGP--INLGLSEEEIENRVKRAMNIVGLDYEDYkDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPK 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 193 VQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLF 247
Cdd:PRK13637 179 GRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVF 233

PRK14267

phosphate ABC transporter ATP-binding protein; Provisional

38-255

3.39e-36

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 131.50 E-value: 3.39e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPIT-----DGSVLYDGEDIRTiPDR---ELRRRMQIVFQDPggSM 109
Cdd:PRK14267  20 IKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNIYS-PDVdpiEVRREVGMVFQYP--NP 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 110 NPRMSVRSIVGEPLQVNRLAEG-AELTQKVADVLDSVGLKREHMNR---FPHEFSGGQKQRLALARALSLDPEFILLDEP 185
Cdd:PRK14267  97 FPHLTIYDNVAIGVKLNGLVKSkKELDERVEWALKKAALWDEVKDRlndYPSNLSGGQRQRLVIARALAMKPKILLMDEP 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 186 TSALDVSVQAQVLNLLEEIQEKlgLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYT 255
Cdd:PRK14267 177 TANIDPVGTAKIEELLFELKKE--YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHELT 244

PRK13633

energy-coupling factor transporter ATPase;

37-238

7.77e-36

energy-coupling factor transporter ATPase;

Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 131.36 E-value: 7.77e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDR-ELRRRMQIVFQDPGGSMnprmsV 115
Cdd:PRK13633  25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENLwDIRNKAGMVFQNPDNQI-----V 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPLQV---NRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:PRK13633 100 ATIVEEDVAFgpeNLGIPPEEIRERVDESLKKVGMY-EYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPS 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 663511184 193 VQAQVLNLLEEIQEKLGLTFVFITHALN-VVNhiSDRVAVMYLGKIV 238
Cdd:PRK13633 179 GRREVVNTIKELNKKYGITIILITHYMEeAVE--ADRIIVMDSGKVV 223

ABC_subfamily_A

cd03263

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...

37-246

9.49e-36

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.

Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 129.55 E-value: 9.49e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDrELRRRMQIVFQDpgGSMNPRMSVR 116
Cdd:cd03263   17 AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRK-AARQSLGYCPQF--DALFDELTVR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 sivgEPLQ-------VNRLAEGAEltqkVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSAL 189
Cdd:cd03263   94 ----EHLRfyarlkgLPKSEIKEE----VELLLRVLGLT-DKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGL 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 190 DVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADL 246
Cdd:cd03263  165 DPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQEL 219

ABCC_MsbA

cd03251

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...

37-249

2.17e-35

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 128.89 E-value: 2.17e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLgrvlLGLIP----ITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSM 109
Cdd:cd03251   17 VLRDISLDIPAGETVALVGPSGSGKSTL----VNLIPrfydVDSGRILIDGHDVRDYTLASLRRQIGLVSQDVflfNDTV 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 110 --NPRMSVRSIVGEP-LQVNRLAEGAELTQKVADVLDSV----GLKrehmnrfpheFSGGQKQRLALARALSLDPEFILL 182
Cdd:cd03251   93 aeNIAYGRPGATREEvEEAARAANAHEFIMELPEGYDTVigerGVK----------LSGGQRQRIAIARALLKDPPILIL 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 183 DEPTSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDK 249
Cdd:cd03251  163 DEATSALDTESERLVQAALERLMK--NRTTFVIAHRLSTIEN-ADRIVVLEDGKIVERGTHEELLAQ 226

TauB

COG4525

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

34-217

2.18e-35

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 129.60 E-value: 2.18e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrTIPDRElrrRmQIVFQDPGgsMNPRM 113
Cdd:COG4525   19 PQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPV-TGPGAD---R-GVVFQKDA--LLPWL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:COG4525   92 NVLDNVAFGLRLRGVPK-AERRARAEELLALVGLA-DFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDALT 169

                        170       180
                 ....*....|....*....|....
gi 663511184 194 QAQVLNLLEEIQEKLGLTFVFITH 217
Cdd:COG4525  170 REQMQELLLDVWQRTGKGVFLITH 193

ABC_TM1139_LivF_branched

cd03224

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...

32-238

2.20e-35

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.

Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 128.71 E-value: 2.20e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  32 KIHVraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElRRRMQIVFQDPGGSMNP 111
Cdd:cd03224   12 KSQI--LFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHE-RARAGIGYVPEGRRIFP 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 RMSVRsivgEPLqvnRLAEGAELTQKVADVLDSVglkrehMNRFP--HEF--------SGGQKQRLALARALSLDPEFIL 181
Cdd:cd03224   89 ELTVE----ENL---LLGAYARRRAKRKARLERV------YELFPrlKERrkqlagtlSGGEQQMLAIARALMSRPKLLL 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 182 LDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03224  156 LDEPSEGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVV 211

ntrCD

TIGR01184

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...

38-252

2.72e-35

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]

Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 128.74 E-value: 2.72e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDI-RTIPDRelrrrmQIVFQDPggSMNPRMSVR 116
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQItEPGPDR------MVVFQNY--SLLPWLTVR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  117 SIVGEPL-QVNRLAEGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:TIGR01184  73 ENIALAVdRVLPDLSKSERRAIVEEHIALVGL-TEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRG 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184  196 QVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVM------YLGKIVEIAntadlFDKPAH 252
Cdd:TIGR01184 152 NLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLtngpaaNIGQILEVP-----FPRPRD 209

PRK11264

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

12-260

3.06e-35

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 129.10 E-value: 3.06e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFpiKGGmlsevkihvRAVDGVDLQIKRGETLGIVGESGCGKTTL------------GRVLLGLIPITDGSV 79
Cdd:PRK11264   4 IEVKNLVKKF--HGQ---------TVLHGIDLEVKPGEVVAIIGPSGSGKTTLlrcinlleqpeaGTIRVGDITIDTARS 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  80 LydGEDIRTIpdRELRRRMQIVFQdpggSMN--P-RMSVRSIVGEPLQVNRLAEGaELTQKVADVLDSVGLKREHmNRFP 156
Cdd:PRK11264  73 L--SQQKGLI--RQLRQHVGFVFQ----NFNlfPhRTVLENIIEGPVIVKGEPKE-EATARARELLAKVGLAGKE-TSYP 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 157 HEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEI-QEKlgLTFVFITHALNVVNHISDRVAVMYLG 235
Cdd:PRK11264 143 RRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLaQEK--RTMVIVTHEMSFARDVADRAIFMDQG 220

                        250       260
                 ....*....|....*....|....*
gi 663511184 236 KIVEIANTADLFDKPAHPYTHALMS 260
Cdd:PRK11264 221 RIVEQGPAKALFADPQQPRTRQFLE 245

ModC

COG4148

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...

27-251

3.54e-35

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis

Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 131.76 E-value: 3.54e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  27 MLsEVKIHVR----AVDgVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP-----IT-DGSVLYDGEDIRTIPDRelRR 96
Cdd:COG4148    2 ML-EVDFRLRrggfTLD-VDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERpdsgrIRlGGEVLQDSARGIFLPPH--RR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  97 RMQIVFQDPggSMNPRMSVRSivgeplqvN-----RLAEGAELTQKVADVLDSVGLkrEH-MNRFPHEFSGGQKQRLALA 170
Cdd:COG4148   78 RIGYVFQEA--RLFPHLSVRG--------NllygrKRAPRAERRISFDEVVELLGI--GHlLDRRPATLSGGERQRVAIG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 171 RALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:COG4148  146 RALLSSPRLLLMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225


                 .
gi 663511184 251 A 251
Cdd:COG4148  226 D 226

hmuV

PRK13548

hemin importer ATP-binding subunit; Provisional

27-238

3.66e-35

hemin importer ATP-binding subunit; Provisional

Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 129.12 E-value: 3.66e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  27 MLSEVKIHVRA-----VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIV 101
Cdd:PRK13548   2 MLEARNLSVRLggrtlLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAVL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 102 FQDPggSMNPRMSVRSIVG---EPLQVNRlaegAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARAL---- 173
Cdd:PRK13548  82 PQHS--SLSFPFTVEEVVAmgrAPHGLSR----AEDDALVAAALAQVDL--AHLaGRDYPQLSGGEQQRVQLARVLaqlw 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 174 --SLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK13548 154 epDGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLV 220

PRK14246

phosphate ABC transporter ATP-binding protein; Provisional

41-255

3.89e-35

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 129.01 E-value: 3.89e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPI------TDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggSMNPRMS 114
Cdd:PRK14246  29 ITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIydskikVDGKVLYFGKDIFQIDAIKLRKEVGMVFQQP--NPFPHLS 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKRE---HMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:PRK14246 107 IYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEvydRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSMIDI 186

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663511184 192 SVQAQVLNLLEEIQEKlgLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYT 255
Cdd:PRK14246 187 VNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELT 248

cbiO

PRK13632

cobalt transporter ATP-binding subunit; Provisional

37-247

4.40e-35

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 129.34 E-value: 4.40e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPG----GSmnpr 112
Cdd:PRK13632  24 ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIRKKIGIIFQNPDnqfiGA---- 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 mSVRSIVGEPLQvNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:PRK13632 100 -TVEDDIAFGLE-NKKVPPKKMKDIIDDLAKKVGME-DYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPK 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 193 VQAQVLNLLEEIQEKLGLTFVFITHALN-VVNhiSDRVAVMYLGKIVEIANTADLF 247
Cdd:PRK13632 177 GKREIKKIMVDLRKTRKKTLISITHDMDeAIL--ADKVIVFSEGKLIAQGKPKEIL 230

PRK10070

proline/glycine betaine ABC transporter ATP-binding protein ProV;

37-262

1.68e-34

proline/glycine betaine ABC transporter ATP-binding protein ProV;

Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 130.92 E-value: 1.68e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELR--RRMQIVFQDPGGSMNPRMS 114
Cdd:PRK10070  43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRevRRKKIAMVFQSFALMPHMT 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVNRLAeGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:PRK10070 123 VLDNTAFGMELAGIN-AEERREKALDALRQVGLE-NYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIR 200

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 195 AQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALMSAI 262
Cdd:PRK10070 201 TEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGV 268

HisP

COG4598

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];

40-250

2.42e-34

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 126.84 E-value: 2.42e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGL-IPiTDGSVLYDGEDIRTIPDRE-------------LRRRMQIVFQdp 105
Cdd:COG4598   26 GVSLTARKGDVISIIGSSGSGKSTFLRCINLLeTP-DSGEIRVGGEEIRLKPDRDgelvpadrrqlqrIRTRLGMVFQ-- 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 106 ggSMN--PRMSVRSIVGE-PLQVNRLAEgAELTQKVADVLDSVGL--KREHmnrFPHEFSGGQKQRLALARALSLDPEFI 180
Cdd:COG4598  103 --SFNlwSHMTVLENVIEaPVHVLGRPK-AEAIERAEALLAKVGLadKRDA---YPAHLSGGQQQRAAIARALAMEPEVM 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663511184 181 LLDEPTSALDVSVQAQVL----NLLEEiqeklGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:COG4598  177 LFDEPTSALDPELVGEVLkvmrDLAEE-----GRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNP 245

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

3-246

5.12e-34

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 131.46 E-value: 5.12e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    3 EESRDGKVLIEVKGMKK-WFPIKGGMlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLY 81
Cdd:TIGR03269 271 CEVEVGEPIIKVRNVSKrYISVDRGV-------VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNV 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   82 D-GEDI--RTIPDRELRRR----MQIVFQDPGgsMNPRMSVRSIVGEPLQVNRLAEGAELtqKVADVLDSVGLK----RE 150
Cdd:TIGR03269 344 RvGDEWvdMTKPGPDGRGRakryIGILHQEYD--LYPHRTVLDNLTEAIGLELPDELARM--KAVITLKMVGFDeekaEE 419

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  151 HMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVA 230
Cdd:TIGR03269 420 ILDKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAA 499

                         250
                  ....*....|....*.
gi 663511184  231 VMYLGKIVEIANTADL 246
Cdd:TIGR03269 500 LMRDGKIVKIGDPEEI 515

ABCC_MRP_domain2

cd03244

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...

37-250

5.67e-34

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 124.91 E-value: 5.67e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSMnpRM 113
Cdd:cd03244   19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSRISIIPQDPvlfSGTI--RS 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVrsivgEPLqvNRLAEGAeltqkVADVLDSVGLKREHMNRFPHE----------FSGGQKQRLALARALSLDPEFILLD 183
Cdd:cd03244   97 NL-----DPF--GEYSDEE-----LWQALERVGLKEFVESLPGGLdtvveeggenLSVGQRQLLCLARALLRKSKILVLD 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 184 EPTSALDVSVQAQVLNLleeIQEKL-GLTFVFITHALNVVNHiSDRVAVMYLGKIVEiantadlFDKP 250
Cdd:cd03244  165 EATASVDPETDALIQKT---IREAFkDCTVLTIAHRLDTIID-SDRILVLDKGRVVE-------FDSP 221

ABCC_Hemolysin

cd03252

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...

37-249

6.51e-34

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.

Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 125.29 E-value: 6.51e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQ----------DPG 106
Cdd:cd03252   17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVVLQenvlfnrsirDNI 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNPRMSVRSIVgeplQVNRLAEGAELTQKVADVLDS------VGLkrehmnrfphefSGGQKQRLALARALSLDPEFI 180
Cdd:cd03252   97 ALADPGMSMERVI----EAAKLAGAHDFISELPEGYDTivgeqgAGL------------SGGQRQRIAIARALIHNPRIL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 181 LLDEPTSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDK 249
Cdd:cd03252  161 IFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAE 226

NHLM_micro_ABC2

TIGR03797

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...

39-250

2.22e-33

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]

Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 130.85 E-value: 2.22e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDpgGSMNPRMSVRSI 118
Cdd:TIGR03797 470 DDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDLAGLDVQAVRRQLGVVLQN--GRLMSGSIFENI 547

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  119 VG-EPLQVNRLAEGAELtqkvadvldsVGLKrEHMNRFP---H--------EFSGGQKQRLALARALSLDPEFILLDEPT 186
Cdd:TIGR03797 548 AGgAPLTLDEAWEAARM----------AGLA-EDIRAMPmgmHtvisegggTLSGGQRQRLLIARALVRKPRILLFDEAT 616

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663511184  187 SALDVSVQAQVLNLLeeiqEKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:TIGR03797 617 SALDNRTQAIVSESL----ERLKVTRIVIAHRLSTIRN-ADRIYVLDAGRVVQQGTYDELMARE 675

ABCC_Protease_Secretion

cd03246

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...

38-237

2.41e-33

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.

Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 121.55 E-value: 2.41e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDpggsmnprmsvrs 117
Cdd:cd03246   18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVGYLPQD------------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 118 ivgeplqvNRLAEGAeltqkVADVLdsvglkrehmnrfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQV 197
Cdd:cd03246   85 --------DELFSGS-----IAENI----------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERAL 135

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 663511184 198 LNLLEEIQEKlGLTFVFITHALNVVNhISDRVAVMYLGKI 237
Cdd:cd03246  136 NQAIAALKAA-GATRIVIAHRPETLA-SADRILVLEDGRV 173

COG4559

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

27-238

2.49e-33

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 124.07 E-value: 2.49e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  27 MLSEVKIHVRA-----VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIV 101
Cdd:COG4559    1 MLEAENLSVRLggrtlLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRRAVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 102 FQDpgGSMNPRMSVRSIVG---EPLQvnrlAEGAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARAL---- 173
Cdd:COG4559   81 PQH--SSLAFPFTVEEVVAlgrAPHG----SSAAQDRQIVREALALVGL--AHLaGRSYQTLSGGEQQRVQLARVLaqlw 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 174 ---SLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:COG4559  153 epvDGGPRWLFLDEPTSALDLAHQHAVLRLARQLARR-GGGVVAVLHDLNLAAQYADRILLLHQGRLV 219

ArtP

COG4161

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

41-257

2.64e-33

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 123.58 E-value: 2.64e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVL-LGLIPiTDGSVLYDGE--DIRTIPD----RELRRRMQIVFQDPggSMNPRM 113
Cdd:COG4161   21 INLECPSGETLVLLGPSGAGKSSLLRVLnLLETP-DSGQLNIAGHqfDFSQKPSekaiRLLRQKVGMVFQQY--NLWPHL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVR-SIVGEPLQVNRLAEgAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:COG4161   98 TVMeNLIEAPCKVLGLSK-EQAREKAMKLLARLRLT-DKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPE 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 193 VQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEiANTADLFdkpAHPYTHA 257
Cdd:COG4161  176 ITAQVVEIIRELSQT-GITQVIVTHEVEFARKVASQVVYMEKGRIIE-QGDASHF---TQPQTEA 235

heterocyst_DevA

TIGR02982

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...

40-238

3.52e-33

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.

Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 122.82 E-value: 3.52e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDREL---RRRMQIVFQdpGGSMNPRMSVR 116
Cdd:TIGR02982  23 DINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVLGQELHGASKKQLvqlRRRIGYIFQ--AHNLLGFLTAR 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  117 SIVGEPLQVNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQ 196
Cdd:TIGR02982 101 QNVQMALELQPNLSYQEARERARAMLEAVGLG-DHLNYYPHNLSGGQKQRVAIARALVHHPKLVLADEPTAALDSKSGRD 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 663511184  197 VLNLLEEIQEKLGLTFVFITHAlNVVNHISDRVAVMYLGKIV 238
Cdd:TIGR02982 180 VVELMQKLAKEQGCTILMVTHD-NRILDVADRILQMEDGKLL 220

ABCC_ATM1_transporter

cd03253

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...

39-249

3.84e-33

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 123.11 E-value: 3.84e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDpggsmnprmSV--R 116
Cdd:cd03253   18 KDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRAIGVVPQD---------TVlfN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGEPLQVNRLA---EGAELTQKVADVLDSVglkrehmNRFPHEF-----------SGGQKQRLALARALSLDPEFILL 182
Cdd:cd03253   89 DTIGYNIRYGRPDatdEEVIEAAKAAQIHDKI-------MRFPDGYdtivgerglklSGGEKQRVAIARAILKNPPILLL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 183 DEPTSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDK 249
Cdd:cd03253  162 DEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEELLAK 225

thiQ

PRK10771

thiamine ABC transporter ATP-binding protein ThiQ;

42-246

5.74e-33

thiamine ABC transporter ATP-binding protein ThiQ;

Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 122.38 E-value: 5.74e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  42 DLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRelRRRMQIVFQDpgGSMNPRMSVRSIVGE 121
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPS--RRPVSMLFQE--NNLFSHLTVAQNIGL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 122 PLQVNrLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLL 201
Cdd:PRK10771  95 GLNPG-LKLNAAQREKLHAIARQMGIE-DLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLV 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 663511184 202 EEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADL 246
Cdd:PRK10771 173 SQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217

cbiO

PRK13639

cobalt transporter ATP-binding subunit; Provisional

37-250

8.00e-33

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 123.26 E-value: 8.00e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTipDR----ELRRRMQIVFQDPGGSMNPR 112
Cdd:PRK13639  17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKY--DKksllEVRKTVGIVFQNPDDQLFAP 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 MSVRSIVGEPLQVNRLAEgaELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:PRK13639  95 TVEEDVAFGPLNLGLSKE--EVEKRVKEALKAVGME-GFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPM 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 193 VQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:PRK13639 172 GASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDI 228

PRK13651

cobalt transporter ATP-binding subunit; Provisional

12-245

2.11e-32

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 122.89 E-value: 2.11e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIKggmlseVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSV--LYDGEDIRTI 89
Cdd:PRK13651   3 IKVKNIVKIFNKK------LPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewIFKDEKNKKK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  90 PDR----------------------ELRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNrlAEGAELTQKVADVLDSVGL 147
Cdd:PRK13651  77 TKEkekvleklviqktrfkkikkikEIRRRVGVVFQFAEYQLFEQTIEKDIIFGPVSMG--VSKEEAKKRAAKYIELVGL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 148 KREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISD 227
Cdd:PRK13651 155 DESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWTK 233

                        250
                 ....*....|....*...
gi 663511184 228 RVAVMYLGKIVEIANTAD 245
Cdd:PRK13651 234 RTIFFKDGKIIKDGDTYD 251

cbiO

PRK13646

energy-coupling factor transporter ATPase;

37-249

2.28e-32

energy-coupling factor transporter ATPase;

Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 122.58 E-value: 2.28e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD----RELRRRMQIVFQDPGGSMNPR 112
Cdd:PRK13646  22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKdkyiRPVRKRIGMVFQFPESQLFED 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 MSVRSIVGEPLQVNRLAEgaELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:PRK13646 102 TVEREIIFGPKNFKMNLD--EVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDPQ 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 193 VQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDK 249
Cdd:PRK13646 180 SKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKD 236

ugpC

PRK11650

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

35-251

3.18e-32

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 123.41 E-value: 3.18e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElrRRMQIVFQdpggsmN---- 110
Cdd:PRK11650  17 TQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPAD--RDIAMVFQ------Nyaly 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 111 PRMSVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:PRK11650  89 PHMSVRENMAYGLKIRGMPK-AEIEERVAEAARILEL-EPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLD 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 191 VSVQAQVLNLLEEIQEKLGLTFVFITH----ALNvvnhISDRVAVMYLGKIVEIANTADLFDKPA 251
Cdd:PRK11650 167 AKLRVQMRLEIQRLHRRLKTTSLYVTHdqveAMT----LADRVVVMNGGVAEQIGTPVEVYEKPA 227

ABC_ThiQ_thiamine_transporter

cd03298

ATP-binding cassette domain of the thiamine transport system; Part of the ...

42-238

3.77e-32

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 119.91 E-value: 3.77e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  42 DLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElrRRMQIVFQDpgGSMNPRMSVRSIVGE 121
Cdd:cd03298   18 DLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPAD--RPVSMLFQE--NNLFAHLTVEQNVGL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 122 PLqVNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLL 201
Cdd:cd03298   94 GL-SPGLKLTAEDRQAIEVALARVGLA-GLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLV 171

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 663511184 202 EEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03298  172 LDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIA 208

YnjD

COG4136

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...

28-245

4.28e-32

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];

Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 119.51 E-value: 4.28e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  28 LSEVKIHVRA---VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLG-LIPI--TDGSVLYDGEDIRTIPDRelRRRMQIV 101
Cdd:COG4136    4 LENLTITLGGrplLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGtLSPAfsASGEVLLNGRRLTALPAE--QRRIGIL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 102 FQDPggSMNPRMSVrsivGE------PLQVNRlaegAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARALS 174
Cdd:COG4136   82 FQDD--LLFPHLSV----GEnlafalPPTIGR----AQRRARVEQALEEAGL--AGFaDRDPATLSGGQRARVALLRALL 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184 175 LDPEFILLDEPTSALDVSVQAQVLNL-LEEIQEkLGLTFVFITHALNvvnhisDRVAVmylGKIVEIANTAD 245
Cdd:COG4136  150 AEPRALLLDEPFSKLDAALRAQFREFvFEQIRQ-RGIPALLVTHDEE------DAPAA---GRVLDLGNWQH 211

PRK13657

glucan ABC transporter ATP-binding protein/ permease;

36-252

5.06e-32

glucan ABC transporter ATP-binding protein/ permease;

Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 126.23 E-value: 5.06e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGgSMNprmsv 115
Cdd:PRK13657 349 QGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRRNIAVVFQDAG-LFN----- 422

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIvGEPLQVNR-------LAEGAELTQ------KVADVLDSVGLKREHMnrfpheFSGGQKQRLALARALSLDPEFILL 182
Cdd:PRK13657 423 RSI-EDNIRVGRpdatdeeMRAAAERAQahdfieRKPDGYDTVVGERGRQ------LSGGERQRLAIARALLKDPPILIL 495

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 183 DEPTSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKPAH 252
Cdd:PRK13657 496 DEATSALDVETEAKVKAALDELMK--GRTTFIIAHRLSTVRN-ADRILVFDNGRVVESGSFDELVARGGR 562

cbiO

PRK13645

energy-coupling factor transporter ATPase;

36-247

5.27e-32

energy-coupling factor transporter ATPase;

Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 121.65 E-value: 5.27e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDG----EDIRTIPD-RELRRRMQIVFQDPGGSMN 110
Cdd:PRK13645  25 KALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDyaipANLKKIKEvKRLRKEIGLVFQFPEYQLF 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 111 PRMSVRSIVGEPlqVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:PRK13645 105 QETIEKDIAFGP--VNLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLD 182

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 191 VSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLF 247
Cdd:PRK13645 183 PKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239

PRK14239

phosphate transporter ATP-binding protein; Provisional

36-255

5.52e-32

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 120.65 E-value: 5.52e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVL--LG-LIP--ITDGSVLYDGEDI--RTIPDRELRRRMQIVFQDPggs 108
Cdd:PRK14239  19 KALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNdLNPevTITGSIVYNGHNIysPRTDTVDLRKEIGMVFQQP--- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 109 mNP-RMSVRSIVGEPLQVN------RLAEGAELTQKVADVLDSVglkREHMNRFPHEFSGGQKQRLALARALSLDPEFIL 181
Cdd:PRK14239  96 -NPfPMSIYENVVYGLRLKgikdkqVLDEAVEKSLKGASIWDEV---KDRLHDSALGLSGGQQQRVCIARVLATSPKIIL 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663511184 182 LDEPTSALDVSVQAQVLNLLEEIQEKlgLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYT 255
Cdd:PRK14239 172 LDEPTSALDPISAGKIEETLLGLKDD--YTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNPKHKET 243

ABC_drug_resistance_like

cd03264

ABC-type multidrug transport system, ATPase component; The biological function of this family ...

36-238

7.99e-32

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 118.83 E-value: 7.99e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGeTLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDrELRRRMQIVFQDPGGSmnPRMSV 115
Cdd:cd03264   14 RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQ-KLRRRIGYLPQEFGVY--PNFTV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSivgeplQVNRLA-----EGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:cd03264   90 RE------FLDYIAwlkgiPSKEVKARVDEVLELVNLG-DRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLD 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 663511184 191 VSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03264  163 PEERIRFRNLLSELGE--DRIVILSTHIVEDVESLCNQVAVLNKGKLV 208

modC_ABC

TIGR02142

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...

41-256

8.35e-32

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]

Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 122.53 E-value: 8.35e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP------ITDGSVLYDGEDIRTIPDRelRRRMQIVFQDpgGSMNPRMS 114
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRpdegeiVLNGRTLFDSRKGIFLPPE--KRRIGYVFQE--ARLFPHLS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  115 VRsivGEPLQVNRLAEGAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:TIGR02142  92 VR---GNLRYGMKRARPSERRISFERVIELLGI--GHLlGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPR 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184  194 QAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTH 256
Cdd:TIGR02142 167 KYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPWLA 229

cbiO

PRK13650

energy-coupling factor transporter ATPase;

38-268

1.20e-31

energy-coupling factor transporter ATPase;

Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 120.22 E-value: 1.20e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSMnPRMSVRS 117
Cdd:PRK13650  23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIRHKIGMVFQNPDNQF-VGATVED 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 118 IVGEPLQvNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQV 197
Cdd:PRK13650 102 DVAFGLE-NKGIPHEEMKERVNEALELVGMQ-DFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLEL 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 198 LNLLEEIQEKLGLTFVFITHALNVVNhISDRVAVMYLGKIVEIANTADLFDKPAH--------PYTHALMSAIPEPSLE 268
Cdd:PRK13650 180 IKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPRELFSRGNDllqlgldiPFTTSLVQSLRQNGYD 257

SufC

COG0396

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...

30-239

1.80e-31

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 118.63 E-value: 1.80e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  30 EVK-IHVrAVD------GVDLQIKRGETLGIVGESGCGKTTLGRVLLGlIP---ITDGSVLYDGEDIRTIPDRElRRRMQ 99
Cdd:COG0396    2 EIKnLHV-SVEgkeilkGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMG-HPkyeVTSGSILLDGEDILELSPDE-RARAG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 100 I--VFQDP----GGSMNP--RMSVRSIVGEPLQVnrlaegAELTQKVADVLDSVGLKREHMNRFPHE-FSGGQKQRLALA 170
Cdd:COG0396   79 IflAFQYPveipGVSVSNflRTALNARRGEELSA------REFLKLLKEKMKELGLDEDFLDRYVNEgFSGGEKKRNEIL 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 663511184 171 RALSLDPEFILLDEPTSALDV-SVQAqVLNLLEEIQEKlGLTFVFITHALNVVNHIS-DRVAVMYLGKIVE 239
Cdd:COG0396  153 QMLLLEPKLAILDETDSGLDIdALRI-VAEGVNKLRSP-DRGILIITHYQRILDYIKpDFVHVLVDGRIVK 221

cbiO

PRK13648

cobalt transporter ATP-binding subunit; Provisional

37-249

3.56e-31

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 118.70 E-value: 3.56e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSMnprmsVR 116
Cdd:PRK13648  24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKHIGIVFQNPDNQF-----VG 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGEPLQV---NRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:PRK13648  99 SIVKYDVAFgleNHAVPYDEMHRRVSEALKQVDML-ERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDA 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 194 QAQVLNLLEEIQEKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDK 249
Cdd:PRK13648 178 RQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDH 232

CeuD

COG4604

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...

38-250

3.93e-31

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 118.26 E-value: 3.93e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggSMNPRMSVRS 117
Cdd:COG4604   17 LDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKRLAILRQEN--HINSRLTVRE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 118 IVG---EPLQVNRLaeGAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:COG4604   95 LVAfgrFPYSKGRL--TAEDREIIDEAIAYLDL--EDLaDRYLDELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDMKH 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 194 QAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:COG4604  171 SVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEIITPE 227

LivF

COG0410

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...

34-251

7.18e-31

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];

Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 117.01 E-value: 7.18e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRR-----MQI--VFqdpg 106
Cdd:COG0410   15 GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLgigyvPEGrrIF---- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 gsmnPRMSVRsivgEPLQVnrlaeGAEL---TQKVADVLDSVglkrehMNRFP--HEF--------SGGQKQRLALARAL 173
Cdd:COG0410   91 ----PSLTVE----ENLLL-----GAYArrdRAEVRADLERV------YELFPrlKERrrqragtlSGGEQQMLAIGRAL 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 174 SLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPA 251
Cdd:COG0410  152 MSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLADPE 228

cbiO

PRK13640

energy-coupling factor transporter ATPase;

37-250

9.36e-31

energy-coupling factor transporter ATPase;

Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 117.98 E-value: 9.36e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLI---PITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSMnprm 113
Cdd:PRK13640  22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlpdDNPNSKITVDGITLTAKTVWDIREKVGIVFQNPDNQF---- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 sVRSIVGEPLQV---NRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:PRK13640  98 -VGATVGDDVAFgleNRAVPRPEMIKIVRDVLADVGML-DYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLD 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 191 VSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:PRK13640 176 PAGKEQILKLIRKLKKKNNLTVISITHDIDEANM-ADQVLVLDDGKLLAQGSPVEIFSKV 234

oligo_HPY

TIGR01727

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...

236-326

1.09e-30

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 213647 [Multi-domain] Cd Length: 87 Bit Score: 111.69 E-value: 1.09e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  236 KIVEIANTADLFDKPAHPYTHALMSAIPEPSleKASRERIVLSGDVPSPANPPPGCRFHTRCPIAVEgVCDVVDPPLETI 315
Cdd:TIGR01727   1 KIVETGPAEEIFKNPLHPYTKALLSAIPTIK--KRDRKLISIPGEVPSLINLPSGCRFYPRCPYAQD-ECRKEPPALVEI 77

                          90
                  ....*....|.
gi 663511184  316 DfDDHAVACHF 326
Cdd:TIGR01727  78 A-EGHRVACHL 87

ABC_BcrA_bacitracin_resist

cd03268

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...

34-239

1.68e-30

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.

Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 115.39 E-value: 1.68e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTipDRELRRRMQIVFQDPGgsMNPRM 113
Cdd:cd03268   12 KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQK--NIEALRRIGALIEAPG--FYPNL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRsivgEPLQVNRLAEGAElTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:cd03268   88 TAR----ENLRLLARLLGIR-KKRIDEVLDVVGLK-DSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDG 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 663511184 194 QAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVE 239
Cdd:cd03268  162 IKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKLIE 206

cbiO

PRK13643

energy-coupling factor transporter ATPase;

36-258

1.96e-30

energy-coupling factor transporter ATPase;

Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 117.14 E-value: 1.96e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYdGEDIRTIPDRE-----LRRRMQIVFQDPGGSMN 110
Cdd:PRK13643  20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTV-GDIVVSSTSKQkeikpVRKKVGVVFQFPESQLF 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 111 PRMSVRSIVGEPLQVNRLAEGAEltQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:PRK13643  99 EETVLKDVAFGPQNFGIPKEKAE--KIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLD 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 191 VSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHAL 258
Cdd:PRK13643 177 PKARIEMMQLFESIHQS-GQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQEVDFLKAHEL 243

cbiO

PRK13642

energy-coupling factor transporter ATPase;

35-247

2.20e-30

energy-coupling factor transporter ATPase;

Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 116.73 E-value: 2.20e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSMnprms 114
Cdd:PRK13642  20 VNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRRKIGMVFQNPDNQF----- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVNRLAEG---AELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:PRK13642  95 VGATVEDDVAFGMENQGiprEEMIKRVDEALLAVNM-LDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDP 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 192 SVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLF 247
Cdd:PRK13642 174 TGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF 228

CydC

TIGR02868

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...

36-219

4.03e-30

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.

Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 120.54 E-value: 4.03e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggsmnprMSV 115
Cdd:TIGR02868 349 PVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSVCAQDA-------HLF 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  116 RSIVGEPLqvnRLAEGAELTQKVADVLDSVGLKrEHMNRFPH-----------EFSGGQKQRLALARALSLDPEFILLDE 184
Cdd:TIGR02868 422 DTTVRENL---RLARPDATDEELWAALERVGLA-DWLRALPDgldtvlgeggaRLSGGERQRLALARALLADAPILLLDE 497

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 663511184  185 PTSALDVSVQAQVLNLLEEIQEklGLTFVFITHAL 219
Cdd:TIGR02868 498 PTEHLDAETADELLEDLLAALS--GRTVVLITHHL 530

urea_trans_UrtE

TIGR03410

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...

37-246

4.12e-30

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 114.93 E-value: 4.12e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElRRRMQIVFQDPGGSMNPRMSVR 116
Cdd:TIGR03410  15 ILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHE-RARAGIAYVPQGREIFPRLTVE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  117 sivgEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQ 196
Cdd:TIGR03410  94 ----ENLLTGLAALPRRSRKIPDEIYELFPVLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEPTEGIQPSIIKD 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 663511184  197 VLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADL 246
Cdd:TIGR03410 170 IGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219

PhnL

COG4778

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...

11-232

4.24e-30

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];

Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 114.84 E-value: 4.24e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPI--KGGmlseVKIHVraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE---- 84
Cdd:COG4778    4 LLEVENLSKTFTLhlQGG----KRLPV--LDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDggwv 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  85 DIRTIPDRE---LRRR--------MQIVfqdpggsmnPRMSVRSIVGEPLqvnrLAEG---AELTQKVADVLDSVGLKRE 150
Cdd:COG4778   78 DLAQASPREilaLRRRtigyvsqfLRVI---------PRVSALDVVAEPL----LERGvdrEEARARARELLARLNLPER 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 151 HMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVA 230
Cdd:COG4778  145 LWDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVV 223


                 ..
gi 663511184 231 VM 232
Cdd:COG4778  224 DV 225

cbiO

PRK13652

cobalt transporter ATP-binding subunit; Provisional

35-250

4.84e-30

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 116.06 E-value: 4.84e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSMNPRMS 114
Cdd:PRK13652  17 KEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGLVFQNPDDQIFSPTV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPlqVNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:PRK13652  97 EQDIAFGP--INLGLDEETVAHRVSSALHMLGLE-ELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGV 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 195 AQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:PRK13652 174 KELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229

cbiO

PRK13634

cobalt transporter ATP-binding subunit; Provisional

36-251

7.16e-30

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 115.89 E-value: 7.16e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYdGEDIRTIPDRE-----LRRRMQIVFQDPGGSMN 110
Cdd:PRK13634  21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTI-GERVITAGKKNkklkpLRKKVGIVFQFPEHQLF 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 111 PRMSVRSIVGEPLQVNRLAEGAEltQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:PRK13634 100 EETVEKDICFGPMNFGVSEEDAK--QKAREMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLD 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 663511184 191 VSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPA 251
Cdd:PRK13634 178 PKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPD 238

TagH

COG1134

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...

12-245

1.26e-29

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 114.02 E-value: 1.26e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIKGGMLSEVKI-----------HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVl 80
Cdd:COG1134    5 IEVENVSKSYRLYHEPSRSLKElllrrrrtrreEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  81 ydgedirtipdrelRRRMQIVFQ-DPGGSMNPRMSVR-------SIVGEPLqvnrlaegAELTQKVADVLDSVGLKrEHM 152
Cdd:COG1134   84 --------------EVNGRVSALlELGAGFHPELTGReniylngRLLGLSR--------KEIDEKFDEIVEFAELG-DFI 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 153 NRfP-HEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAV 231
Cdd:COG1134  141 DQ-PvKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAVRRLCDRAIW 218

                        250
                 ....*....|....
gi 663511184 232 MYLGKIVEIANTAD 245
Cdd:COG1134  219 LEKGRLVMDGDPEE 232

thiQ

TIGR01277

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...

42-243

1.62e-29

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]

Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 112.65 E-value: 1.62e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   42 DLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPdrELRRRMQIVFQDpgGSMNPRMSVRSIVGE 121
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLA--PYQRPVSMLFQE--NNLFAHLTVRQNIGL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  122 PLQVNrLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLL 201
Cdd:TIGR01277  94 GLHPG-LKLNAEQQEKVVDAAQQVGIA-DYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALV 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 663511184  202 EEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANT 243
Cdd:TIGR01277 172 KQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVSDC 213

CP_lyasePhnL

TIGR02324

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P ...

11-229

1.98e-29

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated C-P lysase complex. This protein (PhnL) and the adjacent-encoded PhnK (TIGR02323) resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this C-P lyase complex rather than part of a transporter per se.

Pssm-ID: 131377 [Multi-domain] Cd Length: 224 Bit Score: 112.87 E-value: 1.98e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   11 LIEVKGMKKWFPI--KGGMLSEVkihvraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE---- 84
Cdd:TIGR02324   1 LLEVEDLSKTFTLhqQGGVRLPV------LKNVSLTVNAGECVALSGPSGAGKSTLLKSLYANYLPDSGRILVRHEgawv 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   85 DIRTIPDRELR--RRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKREHMNRFPHEFSGG 162
Cdd:TIGR02324  75 DLAQASPREVLevRRKTIGYVSQFLRVIPRVSALEVVAEPLLERGVPR-EAARARARELLARLNIPERLWHLPPATFSGG 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184  163 QKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRV 229
Cdd:TIGR02324 154 EQQRVNIARGFIADYPILLLDEPTASLDAANRQVVVELIAEAKAR-GAALIGIFHDEEVRELVADRV 219

CydD

TIGR02857

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...

37-232

2.17e-29

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD

Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 118.16 E-value: 2.17e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPG---GSM--NP 111
Cdd:TIGR02857 337 ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAWVPQHPFlfaGTIaeNI 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  112 RMSVRsiVGEPLQVNRLAEGAELTQKVADVLDsvGLKREhMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:TIGR02857 417 RLARP--DASDAEIREALERAGLDEFVAALPQ--GLDTP-IGEGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDA 491

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 663511184  192 SVQAQVLNLLEEIQEklGLTFVFITHALNVVnHISDRVAVM 232
Cdd:TIGR02857 492 ETEAEVLEALRALAQ--GRTVLLVTHRLALA-ALADRIVVL 529

ABC_Carb_Monos_II

cd03215

Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...

36-237

2.64e-29

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 111.37 E-value: 2.64e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElRRRMQIVFqdpggsmnprmsv 115
Cdd:cd03215   14 GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRD-AIRAGIAY------------- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 rsiVGEplqvNRLAEGAELTQKVADVLdsvglkrehmnRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:cd03215   80 ---VPE----DRKREGLVLDLSVAENI-----------ALSSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKA 141

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 663511184 196 QVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:cd03215  142 EIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182

btuD

PRK09536

corrinoid ABC transporter ATPase; Reviewed

35-250

8.39e-29

corrinoid ABC transporter ATPase; Reviewed

Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 115.32 E-value: 8.39e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSMNprMS 114
Cdd:PRK09536  16 TTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVASVPQDTSLSFE--FD 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIV--GEPLQVNRLAEGAEL-TQKVADVLDSVGLKReHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:PRK09536  94 VRQVVemGRTPHRSRFDTWTETdRAAVERAMERTGVAQ-FADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDI 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 192 SVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:PRK09536 173 NHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTAD 230

cbiO

PRK13636

cobalt transporter ATP-binding subunit; Provisional

37-249

8.83e-29

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 112.63 E-value: 8.83e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE--DIRTIPDRELRRRMQIVFQDPGGSMNPRMS 114
Cdd:PRK13636  21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKpiDYSRKGLMKLRESVGMVFQDPDNQLFSASV 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVnRLAEgAELTQKVADVLDSVGLkrEHMNRFP-HEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:PRK13636 101 YQDVSFGAVNL-KLPE-DEVRKRVDNALKRTGI--EHLKDKPtHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMG 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 194 QAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDK 249
Cdd:PRK13636 177 VSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAE 232

MsbA_lipidA

TIGR02203

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...

35-252

3.04e-28

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]

Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 115.20 E-value: 3.04e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSM-- 109
Cdd:TIGR02203 345 RPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLRRQVALVSQDVvlfNDTIan 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  110 NPRMSVRSIVGEPlQVNRLAEGAELtQKVADVLD-----SVGLKREHMnrfphefSGGQKQRLALARALSLDPEFILLDE 184
Cdd:TIGR02203 425 NIAYGRTEQADRA-EIERALAAAYA-QDFVDKLPlgldtPIGENGVLL-------SGGQRQRLAIARALLKDAPILILDE 495

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184  185 PTSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKPAH 252
Cdd:TIGR02203 496 ATSALDNESERLVQAALERLMQ--GRTTLVIAHRLSTIEK-ADRIVVMDDGRIVERGTHNELLARNGL 560

ModF

COG1119

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...

38-217

3.06e-28

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];

Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 110.17 E-value: 3.06e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVL------YDGEDIRtipdrELRRRMQIVFQDPGGSMNP 111
Cdd:COG1119   19 LDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVrlfgerRGGEDVW-----ELRKRIGLVSPALQLRFPR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 RMSVRSIV--------GEPLQVnrlaeGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLD 183
Cdd:COG1119   94 DETVLDVVlsgffdsiGLYREP-----TDEQRERARELLELLGLA-HLADRPFGTLSQGEQRRVLIARALVKDPELLILD 167

                        170       180       190
                 ....*....|....*....|....*....|....
gi 663511184 184 EPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITH 217
Cdd:COG1119  168 EPTAGLDLGARELLLALLDKLAAEGAPTLVLVTH 201

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

8-245

3.17e-28

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 114.74 E-value: 3.17e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   8 GKVLIEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIR 87
Cdd:COG3845    2 MPPALELRGITKRFG-----------GVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVR 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  88 tIPD-RELRRR---MqiVFQDPggSMNPRMSVRS--IVG-EPLQVNRLAEgAELTQKVADVLDSVGLKREhMNRFPHEFS 160
Cdd:COG3845   71 -IRSpRDAIALgigM--VHQHF--MLVPNLTVAEniVLGlEPTKGGRLDR-KAARARIRELSERYGLDVD-PDAKVEDLS 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 161 GGQKQRLALARALSLDPEFILLDEPTSALdvsVQAQVLNLLEEIQE--KLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:COG3845  144 VGEQQRVEILKALYRGARILILDEPTAVL---TPQEADELFEILRRlaAEGKSIIFITHKLREVMAIADRVTVLRRGKVV 220


                 ....*..
gi 663511184 239 EIANTAD 245
Cdd:COG3845  221 GTVDTAE 227

ABC_KpsT_Wzt

cd03220

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...

12-240

5.08e-28

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.

Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 109.16 E-value: 5.08e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIKGGMLSEVK-----------IHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVl 80
Cdd:cd03220    1 IELENVSKSYPTYKGGSSSLKklgilgrkgevGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTV- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  81 ydgedirtipdrelRRRMQIV-FQDPGGSMNPRMSVRS---IVGEPLQVNRlaegAELTQKVADVLDSVGLKrEHMNRFP 156
Cdd:cd03220   80 --------------TVRGRVSsLLGLGGGFNPELTGREniyLNGRLLGLSR----KEIDEKIDEIIEFSELG-DFIDLPV 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 157 HEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGK 236
Cdd:cd03220  141 KTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGK 219


                 ....
gi 663511184 237 IVEI 240
Cdd:cd03220  220 IRFD 223

ArpD

COG4618

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...

38-232

5.33e-28

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];

Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 114.46 E-value: 5.33e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSmnprms 114
Cdd:COG4618  348 LRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRHIGYLPQDVelfDGT------ 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 vrsiVGEplqvN--RLAEG--AELTQ--KVADVLDSVGlkrehmnRFPHEF-----------SGGQKQRLALARALSLDP 177
Cdd:COG4618  422 ----IAE----NiaRFGDAdpEKVVAaaKLAGVHEMIL-------RLPDGYdtrigeggarlSGGQRQRIGLARALYGDP 486

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 178 EFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHiSDRVAVM 232
Cdd:COG4618  487 RLVVLDEPNSNLDDEGEAALAAAIRALKAR-GATVVVITHRPSLLAA-VDKLLVL 539

YhaQ

COG4152

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

35-238

7.95e-28

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 110.20 E-value: 7.95e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrtipDRELRRRMqivfqdpgGSM----- 109
Cdd:COG4152   14 KTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPL----DPEDRRRI--------GYLpeerg 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 110 -NPRMSvrsiVGEplQVNRLAE-----GAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLD 183
Cdd:COG4152   82 lYPKMK----VGE--QLVYLARlkglsKAEAKRRADEWLERLGLG-DRANKKVEELSKGNQQKVQLIAALLHDPELLILD 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 184 EPTSALD-VSVQAqVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:COG4152  155 EPFSGLDpVNVEL-LKDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKV 208

PRK11831

phospholipid ABC transporter ATP-binding protein MlaF;

39-250

1.34e-27

phospholipid ABC transporter ATP-binding protein MlaF;

Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 109.08 E-value: 1.34e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDREL---RRRMQIVFQDpgGSMNPRMSV 115
Cdd:PRK11831  24 DNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLytvRKRMSMLFQS--GALFTDMNV 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPLQVNRLAEGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:PRK11831 102 FDNVAYPLREHTQLPAPLLHSTVMMKLEAVGL-RGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMG 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 196 QVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:PRK11831 181 VLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANP 235

type_I_sec_PrtD

TIGR01842

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...

38-237

1.52e-27

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 113.21 E-value: 1.52e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQD----PG------G 107
Cdd:TIGR01842 334 LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKHIGYLPQDvelfPGtvaeniA 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  108 SMNPRMSVRSIVgeplQVNRLAEGAELTQKVADVLDSV------GLkrehmnrfphefSGGQKQRLALARALSLDPEFIL 181
Cdd:TIGR01842 414 RFGENADPEKII----EAAKLAGVHELILRLPDGYDTVigpggaTL------------SGGQRQRIALARALYGDPKLVV 477

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184  182 LDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHIsDRVAVMYLGKI 237
Cdd:TIGR01842 478 LDEPNSNLDEEGEQALANAIKALKAR-GITVVVITHRPSLLGCV-DKILVLQDGRI 531

ssuB

PRK11247

aliphatic sulfonates transport ATP-binding subunit; Provisional

39-237

1.84e-27

aliphatic sulfonates transport ATP-binding subunit; Provisional

Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 108.61 E-value: 1.84e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDgedirTIPDRELRRRMQIVFQDpgGSMNPRMSVRSI 118
Cdd:PRK11247  29 NQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAG-----TAPLAEAREDTRLMFQD--ARLLPWKKVIDN 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 119 VGEPLQVNRLAEGAEltqkvadVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVL 198
Cdd:PRK11247 102 VGLGLKGQWRDAALQ-------ALAAVGLA-DRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQ 173

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 663511184 199 NLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:PRK11247 174 DLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212

bacteriocin_ABC

TIGR01193

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...

37-248

1.93e-27

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]

Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 113.30 E-value: 1.93e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggsmnpRMSVR 116
Cdd:TIGR01193 489 ILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLRQFINYLPQEP------YIFSG 562

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  117 SIVGEPLQVNRlaEGAElTQKVADVLDSVGLKREhMNRFPHEF-----------SGGQKQRLALARALSLDPEFILLDEP 185
Cdd:TIGR01193 563 SILENLLLGAK--ENVS-QDEIWAACEIAEIKDD-IENMPLGYqtelseegssiSGGQKQRIALARALLTDSKVLILDES 638

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184  186 TSALDVSVQAQVLNLLEEIQEKlglTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFD 248
Cdd:TIGR01193 639 TSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVAKQ-SDKIIVLDHGKIIEQGSHDELLD 697

PRK10908

cell division ATP-binding protein FtsE;

36-238

1.97e-27

cell division ATP-binding protein FtsE;

Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 107.65 E-value: 1.97e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRE---LRRRMQIVFQDPGGSMNpr 112
Cdd:PRK10908  16 QALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREvpfLRRQIGMIFQDHHLLMD-- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 MSVRSIVGEPLQVNRlAEGAELTQKVADVLDSVGLKREHMNrFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:PRK10908  94 RTVYDNVAIPLIIAG-ASGDDIRRRVSAALDKVGLLDKAKN-FPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDA 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 663511184 193 VQAQVLNLLEEIQeKLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK10908 172 LSEGILRLFEEFN-RVGVTVLMATHDIGLISRRSYRMLTLSDGHLH 216

cbiO

PRK13644

energy-coupling factor transporter ATPase;

37-251

2.83e-27

energy-coupling factor transporter ATPase;

Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 108.54 E-value: 2.83e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD-RELRRRMQIVFQDPGGSMNPRMSV 115
Cdd:PRK13644  17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKlQGIRKLVGIVFQNPETQFVGRTVE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPlqVNRLAEGAELTQKVADVLDSVGLKReHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:PRK13644  97 EDLAFGP--ENLCLPPIEIRKRVDRALAEIGLEK-YRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGI 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 196 QVLNLLEEIQEKlGLTFVFITHALNVVnHISDRVAVMYLGKIVEIANTADLFDKPA 251
Cdd:PRK13644 174 AVLERIKKLHEK-GKTIVYITHNLEEL-HDADRIIVMDRGKIVLEGEPENVLSDVS 227

PRK14243

phosphate transporter ATP-binding protein; Provisional

37-260

2.94e-27

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 107.95 E-value: 2.94e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRV---LLGLIPI--TDGSVLYDGEDI--RTIPDRELRRRMQIVFQDPggsm 109
Cdd:PRK14243  25 AVKNVWLDIPKNQITAFIGPSGCGKSTILRCfnrLNDLIPGfrVEGKVTFHGKNLyaPDVDPVEVRRRIGMVFQKP---- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 110 NP-RMSVRSIVGEPLQVN----RLAEGAELTQKVADVLDSVglkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDE 184
Cdd:PRK14243 101 NPfPKSIYDNIAYGARINgykgDMDELVERSLRQAALWDEV---KDKLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDE 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 185 PTSALDVSVQAQVLNLLEEIQEKlgLTFVFITHALNVVNHISDRVAVM---------YLGKIVEIANTADLFDKPAHPYT 255
Cdd:PRK14243 178 PCSALDPISTLRIEELMHELKEQ--YTIIIVTHNMQQAARVSDMTAFFnveltegggRYGYLVEFDRTEKIFNSPQQQAT 255


                 ....*
gi 663511184 256 HALMS 260
Cdd:PRK14243 256 RDYVS 260

PhnK

COG1101

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

12-238

3.51e-27

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 107.86 E-value: 3.51e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIkgGMLSEVkihvRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPd 91
Cdd:COG1101    2 LELKNLSKTFNP--GTVNEK----RALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLP- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  92 rELRRRMQI--VFQDPggSMN--PRMSV------------------------RSIVGEplQVNRLAEGAE--LTQKVadv 141
Cdd:COG1101   75 -EYKRAKYIgrVFQDP--MMGtaPSMTIeenlalayrrgkrrglrrgltkkrRELFRE--LLATLGLGLEnrLDTKV--- 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 142 ldsvGLkrehmnrfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITH---- 217
Cdd:COG1101  147 ----GL-----------LSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHnmeq 211

                        250       260
                 ....*....|....*....|.
gi 663511184 218 ALNVVNhisdRVAVMYLGKIV 238
Cdd:COG1101  212 ALDYGN----RLIMMHEGRII 228

lolD

PRK11629

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

30-229

4.00e-27

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 106.82 E-value: 4.00e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  30 EVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDR---ELR-RRMQIVFQdp 105
Cdd:PRK11629  17 EGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAakaELRnQKLGFIYQ-- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 106 GGSMNPRMSVRSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKREHMNRfPHEFSGGQKQRLALARALSLDPEFILLDEP 185
Cdd:PRK11629  95 FHHLLPDFTALENVAMPLLIGKKKP-AEINSRALEMLAAVGLEHRANHR-PSELSGGERQRVAIARALVNNPRLVLADEP 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 663511184 186 TSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRV 229
Cdd:PRK11629 173 TGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQL 216

ABCC_cytochrome_bd

cd03247

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...

37-239

5.08e-27

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.

Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 105.09 E-value: 5.08e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrtipdrelrrrmqivfQDPGGSMNPRMSVr 116
Cdd:cd03247   17 VLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPV----------------SDLEKALSSLISV- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 sivgeplqvnrlaegaeLTQKV----ADVLDSVGLKrehmnrfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:cd03247   80 -----------------LNQRPylfdTTLRNNLGRR----------FSGGERQRLALARILLQDAPIVLLDEPTVGLDPI 132

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 663511184 193 VQAQVLNLL-EEIQEKlglTFVFITHALNVVNHIsDRVAVMYLGKIVE 239
Cdd:cd03247  133 TERQLLSLIfEVLKDK---TLIWITHHLTGIEHM-DKILFLENGKIIM 176

ABC_FeS_Assembly

cd03217

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...

38-239

6.91e-27

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.

Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 105.30 E-value: 6.91e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGlIP---ITDGSVLYDGEDIRTIPDRElRRRMQI--VFQDPggsmnPR 112
Cdd:cd03217   16 LKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMG-HPkyeVTEGEILFKGEDITDLPPEE-RARLGIflAFQYP-----PE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 MsvrsivgeplqvnrlaEGAeltqKVADVLDSVGLKrehmnrfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:cd03217   89 I----------------PGV----KNADFLRYVNEG----------FSGGEKKRNEILQLLLLEPDLAILDEPDSGLDID 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 663511184 193 VQAQVLNLLEEIQEKlGLTFVFITHALNVVNHI-SDRVAVMYLGKIVE 239
Cdd:cd03217  139 ALRLVAEVINKLREE-GKSVLIITHYQRLLDYIkPDRVHVLYDGRIVK 185

PRK14258

phosphate ABC transporter ATP-binding protein; Provisional

36-250

8.14e-27

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 107.04 E-value: 8.14e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPI-----TDGSVLYDGEDI--RTIPDRELRRRMQIVFQDPggS 108
Cdd:PRK14258  21 KILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELesevrVEGRVEFFNQNIyeRRVNLNRLRRQVSMVHPKP--N 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 109 MNPrMSVR-------SIVG--EPLQVNRLAEGAeltQKVADVLDSVglkREHMNRFPHEFSGGQKQRLALARALSLDPEF 179
Cdd:PRK14258  99 LFP-MSVYdnvaygvKIVGwrPKLEIDDIVESA---LKDADLWDEI---KHKIHKSALDLSGGQQQRLCIARALAVKPKV 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 180 ILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMY-----LGKIVEIANTADLFDKP 250
Cdd:PRK14258 172 LLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKgnenrIGQLVEFGLTKKIFNSP 247

sufC

TIGR01978

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...

33-239

8.36e-27

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]

Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 106.19 E-value: 8.36e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   33 IHVRAVD-----GVDLQIKRGETLGIVGESGCGKTTLGRVLLG--LIPITDGSVLYDGEDIRTI-PDRELRRRMQIVFQD 104
Cdd:TIGR01978   6 LHVSVEDkeilkGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGhpSYEVTSGTILFKGQDLLELePDERARAGLFLAFQY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  105 PggSMNPRMSVRSIVGEPLQVNRLAEG------AELTQKVADVLDSVGLKREHMNRFPHE-FSGGQKQRLALARALSLDP 177
Cdd:TIGR01978  86 P--EEIPGVSNLEFLRSALNARRSARGeepldlLDFEKLLKEKLALLDMDEEFLNRSVNEgFSGGEKKRNEILQMALLEP 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184  178 EFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHIS-DRVAVMYLGKIVE 239
Cdd:TIGR01978 164 KLAILDEIDSGLDIDALKIVAEGINRLREP-DRSFLIITHYQRLLNYIKpDYVHVLLDGRIVK 225

ATM1

COG5265

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...

39-239

1.12e-26

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 111.07 E-value: 1.12e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQD-------------- 104
Cdd:COG5265  375 KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASLRAAIGIVPQDtvlfndtiayniay 454

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 105 --PGGSMNprmsvrsivgeplQVNRLAEGAELTQKVA---DVLDSV----GLKrehmnrfpheFSGGQKQRLALARALSL 175
Cdd:COG5265  455 grPDASEE-------------EVEAAARAAQIHDFIEslpDGYDTRvgerGLK----------LSGGEKQRVAIARTLLK 511

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663511184 176 DPEFILLDEPTSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVE 239
Cdd:COG5265  512 NPPILIFDEATSALDSRTERAIQAALREVAR--GRTTLVIAHRLSTIVD-ADEILVLEAGRIVE 572

ABC_putative_ATPase

cd03269

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...

35-238

1.64e-26

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 104.67 E-value: 1.64e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrtipDRELRRRMQIVFQDPGgsMNPRMS 114
Cdd:cd03269   13 VTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPL----DIAARNRIGYLPEERG--LYPKMK 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSivgeplQVNRLAEGAELTQKVA-----DVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSAL 189
Cdd:cd03269   87 VID------QLVYLAQLKGLKKEEArrridEWLERLEL-SEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGL 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 663511184 190 DVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03269  160 DPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAV 207

PRK14271

phosphate ABC transporter ATP-binding protein; Provisional

38-255

3.29e-26

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 105.56 E-value: 3.29e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDG-----SVLYDGEDIRTIPD-RELRRRMQIVFQDPggsmNP 111
Cdd:PRK14271  37 LDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSIFNYRDvLEFRRRVGMLFQRP----NP 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 -RMSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGL---KREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTS 187
Cdd:PRK14271 113 fPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLwdaVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTS 192

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 188 ALDVSVQAQVLNLLEEIQEKlgLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYT 255
Cdd:PRK14271 193 ALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAET 258

cbiO

PRK13649

energy-coupling factor transporter ATPase;

36-249

4.10e-26

energy-coupling factor transporter ATPase;

Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 105.21 E-value: 4.10e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD----RELRRRMQIVFQDPGGSMNP 111
Cdd:PRK13649  21 RALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKnkdiKQIRKKVGLVFQFPESQLFE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 RMSVRSIVGEPLQVNRLAEGAELTQKvaDVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:PRK13649 101 ETVLKDVAFGPQNFGVSQEEAEALAR--EKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDP 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 192 SVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDK 249
Cdd:PRK13649 179 KGRKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235

cbiO

PRK13631

cobalt transporter ATP-binding subunit; Provisional

35-251

4.42e-26

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 106.09 E-value: 4.42e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSV----LYDGEDI-----------RTIPD-RELRRRM 98
Cdd:PRK13631  39 LVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdIYIGDKKnnhelitnpysKKIKNfKELRRRV 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  99 QIVFQDPGGSMNPRMSVRSIVGEPlqVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPE 178
Cdd:PRK13631 119 SMVFQFPEYQLFKDTIEKDIMFGP--VALGVKKSEAKKLAKFYLNKMGLDDSYLERSPFGLSGGQKRRVAIAGILAIQPE 196

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184 179 FILLDEPTSALDVSVQAQVLNLLEEiQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPA 251
Cdd:PRK13631 197 ILIFDEPTAGLDPKGEHEMMQLILD-AKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTDQH 268

ABC_YhbG

cd03218

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...

36-251

4.50e-26

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.

Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 104.16 E-value: 4.50e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElRRRMQIVF--QDPggSMNPRM 113
Cdd:cd03218   14 KVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHK-RARLGIGYlpQEA--SIFRKL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVR---SIVGEPLQVNRlaegAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSAL 189
Cdd:cd03218   91 TVEeniLAVLEIRGLSK----KEREEKLEELLEEFHI--THLrKSKASSLSGGERRRVEIARALATNPKFLLLDEPFAGV 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 190 D-VSVQaQVLNLLEEIQEK-LGltfVFIT-HALNVVNHISDRVAVMYLGKIVEIANTADLFDKPA 251
Cdd:cd03218  165 DpIAVQ-DIQKIIKILKDRgIG---VLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANEL 225

PRK13549

xylose transporter ATP-binding subunit; Provisional

11-236

5.03e-26

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 108.48 E-value: 5.03e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP--ITDGSVLYDGEDIR- 87
Cdd:PRK13549   5 LLEMKNITKTFG-----------GVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPhgTYEGEIIFEGEELQa 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  88 -TIPDRElRRRMQIVFQDPggSMNPRMSVRS--IVGEPLQVNRLAEGAELTQKVADVLDSVGLkreHMNrfPH----EFS 160
Cdd:PRK13549  74 sNIRDTE-RAGIAIIHQEL--ALVKELSVLEniFLGNEITPGGIMDYDAMYLRAQKLLAQLKL---DIN--PAtpvgNLG 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 161 GGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGK 236
Cdd:PRK13549 146 LGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGR 220

ABCC_NFT1

cd03369

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...

36-241

5.69e-26

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 103.26 E-value: 5.69e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSMNprmSV 115
Cdd:cd03369   22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTIIPQDPTLFSG---TI 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSivgeplQVNRLAEGAEltqkvADVLDSVGLKREHMNrfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:cd03369   99 RS------NLDPFDEYSD-----EEIYGALRVSEGGLN-----LSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDA 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 663511184 196 QVLNLLEEiqEKLGLTFVFITHALNVVNHIsDRVAVMYLGKIVEIA 241
Cdd:cd03369  163 LIQKTIRE--EFTNSTILTIAHRLRTIIDY-DKILVMDAGEVKEYD 205

YddA

COG4178

ABC-type uncharacterized transport system, permease and ATPase components [General function ...

38-217

2.07e-25

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];

Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 107.20 E-value: 2.07e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLY-DGEDIRTIPDRelrrrmqivfqdpggsmnPRM--- 113
Cdd:COG4178  379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARpAGARVLFLPQR------------------PYLplg 440

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSIVGEPLQVNRLAEgaeltQKVADVLDSVGLKR--EHMN---RFPHEFSGGQKQRLALARALSLDPEFILLDEPTSA 188
Cdd:COG4178  441 TLREALLYPATAEAFSD-----AELREALEAVGLGHlaERLDeeaDWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSA 515

                        170       180
                 ....*....|....*....|....*....
gi 663511184 189 LDVSVQAQVLNLLEEiqEKLGLTFVFITH 217
Cdd:COG4178  516 LDEENEAALYQLLRE--ELPGTTVISVGH 542

PRK11000

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

41-251

3.22e-25

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 104.73 E-value: 3.22e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElrRRMQIVFQDPggSMNPRMSVRSIVG 120
Cdd:PRK11000  22 INLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAE--RGVGMVFQSY--ALYPHLSVAENMS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 121 EPLQVNRlAEGAELTQKVADVLDSvgLKREHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLN 199
Cdd:PRK11000  98 FGLKLAG-AKKEEINQRVNQVAEV--LQLAHLlDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRI 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 663511184 200 LLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPA 251
Cdd:PRK11000 175 EISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPA 226

PRK10247

putative ABC transporter ATP-binding protein YbbL; Provisional

38-227

7.50e-25

putative ABC transporter ATP-binding protein YbbL; Provisional

Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 100.56 E-value: 7.50e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPG--GSmnprmSV 115
Cdd:PRK10247  23 LNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQVSYCAQTPTlfGD-----TV 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPLQVNRLAEGAeltQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:PRK10247  98 YDNLIFPWQIRNQQPDP---AIFLDDLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKH 174

                        170       180       190
                 ....*....|....*....|....*....|..
gi 663511184 196 QVLNLLEEIQEKLGLTFVFITHALNVVNHISD 227
Cdd:PRK10247 175 NVNEIIHRYVREQNIAVLWVTHDKDEINHADK 206

tauB

PRK11248

taurine ABC transporter ATP-binding subunit;

36-217

8.24e-25

taurine ABC transporter ATP-binding subunit;

Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 101.31 E-value: 8.24e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrTIPDRElrrrMQIVFQDPGgsMNPRMSV 115
Cdd:PRK11248  15 PALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPV-EGPGAE----RGVVFQNEG--LLPWRNV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPLQVNRLAEgAELTQKVADVLDSVGLKREHmNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:PRK11248  88 QDNVAFGLQLAGVEK-MQRLEIAHQMLKKVGLEGAE-KRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTRE 165

                        170       180
                 ....*....|....*....|..
gi 663511184 196 QVLNLLEEIQEKLGLTFVFITH 217
Cdd:PRK11248 166 QMQTLLLKLWQETGKQVLLITH 187

livG

PRK11300

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

11-236

1.17e-24

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 100.83 E-value: 1.17e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFpikGGMLsevkihvrAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP 90
Cdd:PRK11300   5 LLSVSGLMMRF---GGLL--------AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 DRELrRRMQIV--FQdpggsmNPR----MSVRS--IVGEPLQVN-------------RLAEgAELTQKVADVLDSVGLkR 149
Cdd:PRK11300  74 GHQI-ARMGVVrtFQ------HVRlfreMTVIEnlLVAQHQQLKtglfsgllktpafRRAE-SEALDRAATWLERVGL-L 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 150 EHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRV 229
Cdd:PRK11300 145 EHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRI 224


                 ....*..
gi 663511184 230 AVMYLGK 236
Cdd:PRK11300 225 YVVNQGT 231

PRK11160

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

37-258

1.38e-24

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 104.52 E-value: 1.38e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLgrvlLGLIP----ITDGSVLYDGEDIRTIPDRELRRRMQIVFQdpggsmnpR 112
Cdd:PRK11160 355 VLKGLSLQIKAGEKVALLGRTGCGKSTL----LQLLTrawdPQQGEILLNGQPIADYSEAALRQAISVVSQ--------R 422

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 MSVRSivgEPLQVN-RLAEGAELTQKVADVLDSVGLKR-----EHMNRFPHE----FSGGQKQRLALARALSLDPEFILL 182
Cdd:PRK11160 423 VHLFS---ATLRDNlLLAAPNASDEALIEVLQQVGLEKlleddKGLNAWLGEggrqLSGGEQRRLGIARALLHDAPLLLL 499

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 183 DEPTSALDVSVQAQVLNLLEE-IQEKlglTFVFITHALNVVNHIsDRVAVMYLGKIVEIANTADLFDKpaHPYTHAL 258
Cdd:PRK11160 500 DEPTEGLDAETERQILELLAEhAQNK---TVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQELLAQ--QGRYYQL 570

cbiO

PRK13647

cobalt transporter ATP-binding subunit; Provisional

36-238

1.42e-24

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 100.97 E-value: 1.42e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPGGSMNPRMSV 115
Cdd:PRK13647  19 KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVGLVFQDPDDQVFSSTVW 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPlqVNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:PRK13647  99 DDVAFGP--VNMGLDKDEVERRVEEALKAVRMW-DFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQE 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 663511184 196 QVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK13647 176 TLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVL 217

fecE

PRK11231

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

36-238

1.51e-24

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 100.47 E-value: 1.51e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggsMNPR-MS 114
Cdd:PRK11231  16 RILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALLPQHH---LTPEgIT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIV--GEPLQVN---RLAEGAEltQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSA 188
Cdd:PRK11231  93 VRELVayGRSPWLSlwgRLSAEDN--ARVNQAMEQTRI--NHLaDRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTY 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 663511184 189 LDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK11231 169 LDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVM 217

cbiO

PRK13641

energy-coupling factor transporter ATPase;

36-273

2.36e-24

energy-coupling factor transporter ATPase;

Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 100.67 E-value: 2.36e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD----RELRRRMQIVFQDPGGSMNP 111
Cdd:PRK13641  21 KGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGnknlKKLRKKVSLVFQFPEAQLFE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 RMSVRSIVGEPLqvNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:PRK13641 101 NTVLKDVEFGPK--NFGFSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDP 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 192 SVQAQVLNLLEEIQeKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHALmsaiPEPSLEKAS 271
Cdd:PRK13641 179 EGRKEMMQLFKDYQ-KAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKEWLKKHYL----DEPATSRFA 253


                 ..
gi 663511184 272 RE 273
Cdd:PRK13641 254 SK 255

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

3-246

2.90e-24

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 103.18 E-value: 2.90e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   3 EESRDGKVLIEVKGMkkWFPIKGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYD 82
Cdd:COG3845  249 APAEPGEVVLEVENL--SVRDDRG--------VPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLD 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  83 GEDIrTIPDRELRRRMQIVF--QDPGGS-MNPRMSV------RSIVGEPLQVN---RLAEGAELTQKVADVLDsVglkre 150
Cdd:COG3845  319 GEDI-TGLSPRERRRLGVAYipEDRLGRgLVPDMSVaenlilGRYRRPPFSRGgflDRKAIRAFAEELIEEFD-V----- 391

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 151 hmnRFPHE------FSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNH 224
Cdd:COG3845  392 ---RTPGPdtparsLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDA-GAAVLLISEDLDEILA 467

                        250       260
                 ....*....|....*....|..
gi 663511184 225 ISDRVAVMYLGKIVEIANTADL 246
Cdd:COG3845  468 LSDRIAVMYEGRIVGEVPAAEA 489

3a01208

TIGR00958

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

40-250

2.93e-24

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 104.03 E-value: 2.93e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSMNPRMSV- 115
Cdd:TIGR00958 499 GLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHRQVALVGQEPvlfSGSVRENIAYg 578

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  116 --RSIVGEPLQVNRLAEGAELTQKVADVLDS-VGLKREHMnrfphefSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:TIGR00958 579 ltDTPDEEIMAAAKAANAHDFIMEFPNGYDTeVGEKGSQL-------SGGQKQRIAIARALVRKPRVLILDEATSALDAE 651

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184  193 VQAqvlnLLEEIQEKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:TIGR00958 652 CEQ----LLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQ 704

PRK11174

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

41-239

3.43e-24

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 103.39 E-value: 3.43e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITdGSVLYDGEDIRTIPDRELRRRMQIVFQDPggsMNPRMSVRSIV- 119
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPYQ-GSLKINGIELRELDPESWRKHLSWVGQNP---QLPHGTLRDNVl 444

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 120 -GEPL----QVNRLAEGA---ELTQKVADVLDS-VGlkrEHMNRFphefSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:PRK11174 445 lGNPDasdeQLQQALENAwvsEFLPLLPQGLDTpIG---DQAAGL----SVGQAQRLALARALLQPCQLLLLDEPTASLD 517

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 663511184 191 VSVQAQVLNLLEeiQEKLGLTFVFITHALNVVNHIsDRVAVMYLGKIVE 239
Cdd:PRK11174 518 AHSEQLVMQALN--AASRRQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQ 563

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

39-225

4.55e-24

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 102.84 E-value: 4.55e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVlydgedirtipdrELRRRMQIVF--QDPGgsMNPRMSVR 116
Cdd:COG0488   15 DDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEV-------------SIPKGLRIGYlpQEPP--LDDDLTVL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIV----GEPLQV------------------NRLAE---------GAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQ 165
Cdd:COG0488   80 DTVldgdAELRALeaeleeleaklaepdedlERLAElqeefealgGWEAEARAEEILSGLGFPEEDLDRPVSELSGGWRR 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 166 RLALARALSLDPEFILLDEPTSALDV-SVQaqvlnLLEEIQEKLGLTFVFITH--AL--NVVNHI 225
Cdd:COG0488  160 RVALARALLSEPDLLLLDEPTNHLDLeSIE-----WLEEFLKNYPGTVLVVSHdrYFldRVATRI 219

cbiO

PRK13638

energy-coupling factor ABC transporter ATP-binding protein;

40-247

2.41e-23

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 97.77 E-value: 2.41e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE--DIRTIPDRELRRRMQIVFQDPGGSMNpRMSVRS 117
Cdd:PRK13638  19 GLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKplDYSKRGLLALRQQVATVFQDPEQQIF-YTDIDS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 118 IVGEPLQVNRLAEgAELTQKVADVLDSVglKREHMNRFPHE-FSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQ 196
Cdd:PRK13638  98 DIAFSLRNLGVPE-AEITRRVDEALTLV--DAQHFRHQPIQcLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQ 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 663511184 197 VLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLF 247
Cdd:PRK13638 175 MIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVF 224

LptB

COG1137

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...

36-242

3.55e-23

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 96.25 E-value: 3.55e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIP-DRelRRRMQI--------VFQdpg 106
Cdd:COG1137   17 TVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPmHK--RARLGIgylpqeasIFR--- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 gsmnpRMSVR---SIVGEPLQVNRlaegAELTQKVADVLDSVGLkrEHMNRFP-HEFSGGQKQRLALARALSLDPEFILL 182
Cdd:COG1137   92 -----KLTVEdniLAVLELRKLSK----KEREERLEELLEEFGI--THLRKSKaYSLSGGERRRVEIARALATNPKFILL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 183 DEPTSALD-VSVqaqvlnllEEIQE--------KLGltfVFIT-H----ALNVVnhisDRVAVMYLGKIV------EIAN 242
Cdd:COG1137  161 DEPFAGVDpIAV--------ADIQKiirhlkerGIG---VLITdHnvreTLGIC----DRAYIISEGKVLaegtpeEILN 225

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

3-246

5.87e-23

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 99.32 E-value: 5.87e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   3 EESRDGKVLIEVKGmkkwfpikggmLSevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYD 82
Cdd:COG1129  248 RAAAPGEVVLEVEG-----------LS----VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLD 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  83 GE--DIRTIPDReLR---------RRMQIVFQDpggsmnprMSVR---SIVgeplQVNRLAEG-----AELTQKVADVLD 143
Cdd:COG1129  313 GKpvRIRSPRDA-IRagiayvpedRKGEGLVLD--------LSIReniTLA----SLDRLSRGglldrRRERALAEEYIK 379

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 144 SVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVN 223
Cdd:COG1129  380 RLRIKTPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVISSELPELL 458

                        250       260
                 ....*....|....*....|...
gi 663511184 224 HISDRVAVMYLGKIVEIANTADL 246
Cdd:COG1129  459 GLSDRILVMREGRIVGELDREEA 481

ABC_NatA_like

cd03267

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...

12-238

7.34e-23

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.

Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 95.48 E-value: 7.34e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPI---KGGMLSEVKIHVR-------AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLY 81
Cdd:cd03267    1 IEVSNLSKSYRVyskEPGLIGSLKSLFKrkyreveALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  82 DGEdirtIP---DRELRRRMQIVFqdpgGSMN-------PRMS---VRSIVG-EPLQV-NRLAEGAELTQkVADVLDSvg 146
Cdd:cd03267   81 AGL----VPwkrRKKFLRRIGVVF----GQKTqlwwdlpVIDSfylLAAIYDlPPARFkKRLDELSELLD-LEELLDT-- 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 147 lkrehmnrfP-HEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHI 225
Cdd:cd03267  150 ---------PvRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEAL 220

                        250
                 ....*....|...
gi 663511184 226 SDRVAVMYLGKIV 238
Cdd:cd03267  221 ARRVLVIDKGRLL 233

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

11-238

1.17e-22

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 98.74 E-value: 1.17e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   11 LIEVKGMKKWFpikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP--ITDGSVLYDGEDI-- 86
Cdd:TIGR02633   1 LLEMKGIVKTF---GG--------VKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPhgTWDGEIYWSGSPLka 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   87 RTIPDRElRRRMQIVFQDPggSMNPRMSVRS--IVGEPLQVN-RLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQ 163
Cdd:TIGR02633  70 SNIRDTE-RAGIVIIHQEL--TLVPELSVAEniFLGNEITLPgGRMAYNAMYLRAKNLLRELQLDADNVTRPVGDYGGGQ 146

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184  164 KQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:TIGR02633 147 QQLVEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHV 220

modC

PRK11144

molybdenum ABC transporter ATP-binding protein ModC;

41-238

2.88e-22

molybdenum ABC transporter ATP-binding protein ModC;

Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 96.10 E-value: 2.88e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLI-P----IT-DGSVLYDGE-DIRTIPDRelrRRMQIVFQDpgGSMNPRM 113
Cdd:PRK11144  17 VNLTLPAQGITAIFGRSGAGKTSLINAISGLTrPqkgrIVlNGRVLFDAEkGICLPPEK---RRIGYVFQD--ARLFPHY 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSivgeplqvN-RLAEGAELTQKVADVLDSVGLkrEH-MNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:PRK11144  92 KVRG--------NlRYGMAKSMVAQFDKIVALLGI--EPlLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDL 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 663511184 192 SVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK11144 162 PRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVK 208

ABCC_TAP

cd03248

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...

34-237

3.18e-22

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.

Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 93.30 E-value: 3.18e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSMN 110
Cdd:cd03248   26 DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHSKVSLVGQEPvlfARSLQ 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 111 PRMSVRSIVGEPLQVNRLAEGA---ELTQKVADVLDS-VGLKREHMnrfphefSGGQKQRLALARALSLDPEFILLDEPT 186
Cdd:cd03248  106 DNIAYGLQSCSFECVKEAAQKAhahSFISELASGYDTeVGEKGSQL-------SGGQKQRVAIARALIRNPQVLILDEAT 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 663511184 187 SALDVSVQAQVLNLLEEIQEKlgLTFVFITHALNVVNHiSDRVAVMYLGKI 237
Cdd:cd03248  179 SALDAESEQQVQQALYDWPER--RTVLVIAHRLSTVER-ADQILVLDGGRI 226

PRK10253

iron-enterobactin ABC transporter ATP-binding protein;

41-249

3.34e-22

iron-enterobactin ABC transporter ATP-binding protein;

Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 94.28 E-value: 3.34e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQD---PGGsmnprMSVRS 117
Cdd:PRK10253  26 LTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNattPGD-----ITVQE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 118 IVG------EPLQVNRLAEGAELTQKVADVLDSVGLKREHMNrfphEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:PRK10253 101 LVArgryphQPLFTRWRKEDEEAVTKAMQATGITHLADQSVD----TLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDI 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663511184 192 SVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIV------EIAnTADLFDK 249
Cdd:PRK10253 177 SHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVaqgapkEIV-TAELIER 239

ABCC_MRP_domain1

cd03250

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...

40-232

4.72e-22

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 92.53 E-value: 4.72e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGedirtipdrelrrRMQIVFQDPGgSMNprMSVRS-I 118
Cdd:cd03250   23 DINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG-------------SIAYVSQEPW-IQN--GTIREnI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 119 V-GEPLQVNRLAEgaeltqkvadVLDSVGLKREhMNRFPH-------E----FSGGQKQRLALARALSLDPEFILLDEPT 186
Cdd:cd03250   87 LfGKPFDEERYEK----------VIKACALEPD-LEILPDgdlteigEkginLSGGQKQRISLARAVYSDADIYLLDDPL 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 663511184 187 SALDVSVQAQVLNLLeeIQEKL--GLTFVFITHALNVVNHiSDRVAVM 232
Cdd:cd03250  156 SAVDAHVGRHIFENC--ILGLLlnNKTRILVTHQLQLLPH-ADQIVVL 200

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

3-235

5.10e-22

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 97.06 E-value: 5.10e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   3 EESRDGKVLIEVKGMKKWFPikggmlsEVKIhvraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVlyd 82
Cdd:COG0488  307 PPERLGKKVLELEGLSKSYG-------DKTL----LDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTV--- 372

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  83 gedirtipdrELRRRMQIVF--QDpGGSMNPRMSVRSIVGeplqvnRLAEGAElTQKVADVLDSVGLKREHMNRFPHEFS 160
Cdd:COG0488  373 ----------KLGETVKIGYfdQH-QEELDPDKTVLDELR------DGAPGGT-EQEVRGYLGRFLFSGDDAFKPVGVLS 434

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 161 GGQKQRLALARALSLDPEFILLDEPTSALDVsvqaQVLNLLEEiqeklGL-----TFVFITH---ALN-VVNHI---SDR 228
Cdd:COG0488  435 GGEKARLALAKLLLSPPNVLLLDEPTNHLDI----ETLEALEE-----ALddfpgTVLLVSHdryFLDrVATRIlefEDG 505


                 ....*..
gi 663511184 229 VAVMYLG 235
Cdd:COG0488  506 GVREYPG 512

GguA

NF040905

sugar ABC transporter ATP-binding protein;

11-239

9.67e-22

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 96.01 E-value: 9.67e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPikgGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPIT--DGSVLYDGE--DI 86
Cdd:NF040905   1 ILEMRGITKTFP---G--------VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGsyEGEILFDGEvcRF 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  87 RTIPDRElRRRMQIVFQDPggSMNPRMSV-RSI-VGEPLQVNRLAEGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQK 164
Cdd:NF040905  70 KDIRDSE-ALGIVIIHQEL--ALIPYLSIaENIfLGNERAKRGVIDWNETNRRARELLAKVGL-DESPDTLVTDIGVGKQ 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 165 QRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVE 239
Cdd:NF040905 146 QLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGRTIE 219

ABCD_peroxisomal_ALDP

cd03223

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...

42-217

1.14e-21

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).

Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 90.29 E-value: 1.14e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  42 DLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSV-LYDGEDIRTIPDRelrrrmqivfqdpggSMNPRMSVRSIVG 120
Cdd:cd03223   21 SFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIgMPEGEDLLFLPQR---------------PYLPLGTLREQLI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 121 EPLQvnrlaegaeltqkvaDVLdsvglkrehmnrfphefSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNL 200
Cdd:cd03223   86 YPWD---------------DVL-----------------SGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQL 133

                        170
                 ....*....|....*..
gi 663511184 201 LEEiqekLGLTFVFITH 217
Cdd:cd03223  134 LKE----LGITVISVGH 146

ccmA

TIGR01189

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...

36-223

1.47e-21

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]

Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 90.88 E-value: 1.47e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDrELRRRMQIVFQDPGgsMNPRMSV 115
Cdd:TIGR01189  14 MLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRD-EPHENILYLGHLPG--LKPELSA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  116 RsivgEPLQV-NRLAEGAELTqkVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:TIGR01189  91 L----ENLHFwAAIHGGAQRT--IEDALAAVGL-TGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGV 163

                         170       180
                  ....*....|....*....|....*....
gi 663511184  195 AQVLNLLEEIQEKLGLTFVFITHALNVVN 223
Cdd:TIGR01189 164 ALLAGLLRAHLARGGIVLLTTHQDLGLVE 192

COG4586

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

12-249

1.64e-21

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 93.61 E-value: 1.64e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPIK----------GGMLSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLY 81
Cdd:COG4586    2 IEVENLSKTYRVYekepglkgalKGLFRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  82 DGEDirtiP---DRELRRRMQIVF-QdpggsmnprmsvRS------IVGEPLQVNRL------AEGAELTQKVADVLDsV 145
Cdd:COG4586   82 LGYV----PfkrRKEFARRIGVVFgQ------------RSqlwwdlPAIDSFRLLKAiyripdAEYKKRLDELVELLD-L 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 146 GlkrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHI 225
Cdd:COG4586  145 G---ELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEAL 221

                        250       260
                 ....*....|....*....|....
gi 663511184 226 SDRVAVMYLGKIVEIANTADLFDK 249
Cdd:COG4586  222 CDRVIVIDHGRIIYDGSLEELKER 245

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

11-238

2.50e-21

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 94.85 E-value: 2.50e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  11 LIEVKGMKKWFPIkggmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDI-RTI 89
Cdd:PRK09700   5 YISMAGIGKSFGP-----------VHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYnKLD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  90 PDRELRRRMQIVFQDPggSMNPRMSVRsivgEPLQVNRL----------AEGAELTQKVADVLDSVGLKREhMNRFPHEF 159
Cdd:PRK09700  74 HKLAAQLGIGIIYQEL--SVIDELTVL----ENLYIGRHltkkvcgvniIDWREMRVRAAMMLLRVGLKVD-LDEKVANL 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 160 SGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQeKLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK09700 147 SISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLR-KEGTAIVYISHKLAEIRRICDRYTVMKDGSSV 224

oligo_HPY

pfam08352

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...

238-303

6.84e-21

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.

Pssm-ID: 400588 [Multi-domain] Cd Length: 65 Bit Score: 85.15 E-value: 6.84e-21

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184  238 VEIANTADLFDKPAHPYTHALMSAIPEPslEKASRERIVLSGDVPSPANPPPGCRFHTRCPIAVEG 303
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRL--DPPKRPLYTIPGNVPSLLELPEGCPFAPRCPFATEE 64

PRK10584

putative ABC transporter ATP-binding protein YbbA; Provisional

40-217

7.39e-21

putative ABC transporter ATP-binding protein YbbA; Provisional

Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 89.84 E-value: 7.39e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIpDRElrRRMQIVFQDPGGSMNPRMSVRSIV 119
Cdd:PRK10584  28 GVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQM-DEE--ARAKLRAKHVGFVFQSFMLIPTLN 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 120 G-EPLQVNRLAEGA---ELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:PRK10584 105 AlENVELPALLRGEssrQSRNGAKALLEQLGLG-KRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGD 183

                        170       180
                 ....*....|....*....|..
gi 663511184 196 QVLNLLEEIQEKLGLTFVFITH 217
Cdd:PRK10584 184 KIADLLFSLNREHGTTLILVTH 205

PRK13539

cytochrome c biogenesis protein CcmA; Provisional

40-203

1.49e-20

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 88.39 E-value: 1.49e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElrrrmQIVFQDPGGSMNPRMSVRsiv 119
Cdd:PRK13539  20 GLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAE-----ACHYLGHRNAMKPALTVA--- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 120 gEPLQVNRLAEGAELTQkVADVLDSVGLKR-EHMnRFpHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVL 198
Cdd:PRK13539  92 -ENLEFWAAFLGGEELD-IAAALEAVGLAPlAHL-PF-GYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFA 167


                 ....*
gi 663511184 199 NLLEE 203
Cdd:PRK13539 168 ELIRA 172

livF

PRK11614

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

27-238

1.75e-20

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 88.78 E-value: 1.75e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  27 MLS--EVKIH---VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPD-RELRRRMQI 100
Cdd:PRK11614   5 MLSfdKVSAHygkIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTaKIMREAVAI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 101 VfqdPGGSmnpRMSVRSIVGEPLQVNR-LAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEF 179
Cdd:PRK11614  85 V---PEGR---RVFSRMTVEENLAMGGfFAERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRL 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 180 ILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK11614 159 LLLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVV 216

PRK11176

lipid A ABC transporter ATP-binding protein/permease MsbA;

37-249

5.29e-20

lipid A ABC transporter ATP-binding protein/permease MsbA;

Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 91.23 E-value: 5.29e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIV------FQDP----- 105
Cdd:PRK11176 358 ALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASLRNQVALVsqnvhlFNDTianni 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 106 GGSMNPRMSVRSIVgeplQVNRLAEGAELTQKVADVLDSV----GLKrehmnrfpheFSGGQKQRLALARALSLDPEFIL 181
Cdd:PRK11176 438 AYARTEQYSREQIE----EAARMAYAMDFINKMDNGLDTVigenGVL----------LSGGQRQRIAIARALLRDSPILI 503

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 182 LDEPTSALDVSVQAQVLNLLEEIQEKlgLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDK 249
Cdd:PRK11176 504 LDEATSALDTESERAIQAALDELQKN--RTSLVIAHRLSTIEK-ADEILVVEDGEIVERGTHAELLAQ 568

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

2-237

6.84e-20

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 90.65 E-value: 6.84e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    2 TEESRDGKVLIEVKGMKKWFPIKGgmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP-ITDGSVL 80
Cdd:TIGR02633 248 HEPHEIGDVILEARNLTCWDVINP--------HRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPgKFEGNVF 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   81 YDGE--DIRTiPDRELRRRMQIVFQD-PGGSMNPRMSV-RSIVGEPLQ----VNRLAEGAELtqkvaDVLDSvGLKREHM 152
Cdd:TIGR02633 320 INGKpvDIRN-PAQAIRAGIAMVPEDrKRHGIVPILGVgKNITLSVLKsfcfKMRIDAAAEL-----QIIGS-AIQRLKV 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  153 NRFpHEF------SGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHIS 226
Cdd:TIGR02633 393 KTA-SPFlpigrlSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLS 470

                         250
                  ....*....|.
gi 663511184  227 DRVAVMYLGKI 237
Cdd:TIGR02633 471 DRVLVIGEGKL 481

galliderm_ABC

TIGR03740

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...

37-237

7.42e-20

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.

Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 86.68 E-value: 7.42e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrtipDRELRRRMQIVFQDPGGSMNprMSVR 116
Cdd:TIGR03740  15 AVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPW----TRKDLHKIGSLIESPPLYEN--LTAR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  117 sivgEPLQVNRLAEGAElTQKVADVLDSVGLKREHMNRfPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD-VSVQa 195
Cdd:TIGR03740  89 ----ENLKVHTTLLGLP-DSRIDEVLNIVDLTNTGKKK-AKQFSLGMKQRLGIAIALLNHPKLLILDEPTNGLDpIGIQ- 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 663511184  196 QVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:TIGR03740 162 ELRELIRSFPEQ-GITVILSSHILSEVQQLADHIGIISEGVL 202

PRK10535

macrolide ABC transporter ATP-binding protein/permease MacB;

35-266

7.61e-20

macrolide ABC transporter ATP-binding protein/permease MacB;

Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 90.94 E-value: 7.61e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDREL----RRRMQIVFQDPggSMN 110
Cdd:PRK10535  21 VEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALaqlrREHFGFIFQRY--HLL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 111 PRMSVRSIVGEPlQVNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALD 190
Cdd:PRK10535  99 SHLTAAQNVEVP-AVYAGLERKQRLLRAQELLQRLGLE-DRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALD 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 191 VSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHiSDRVAVMYLGKIVeiantADLFDKPAHPYTHALMSAIPEPS 266
Cdd:PRK10535 177 SHSGEEVMAILHQLRDR-GHTVIIVTHDPQVAAQ-AERVIEIRDGEIV-----RNPPAQEKVNVAGGTEPVVNTAS 245

COG4674

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

36-237

8.23e-20

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 87.09 E-value: 8.23e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElRRRMQIV--FQDPGG------ 107
Cdd:COG4674   24 KALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGLDEHE-IARLGIGrkFQKPTVfeeltv 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 108 ------SMNPRMSVRSIVGEPLqvnrlaeGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFIL 181
Cdd:COG4674  103 fenlelALKGDRGVFASLFARL-------TAEERDRIEEVLETIGLT-DKADRLAGLLSHGQKQWLEIGMLLAQDPKLLL 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184 182 LDEPTSALDVSVQAQVLNLLEEIQEKlgltfvfitHALNVVNH-------ISDRVAVMYLGKI 237
Cdd:COG4674  175 LDEPVAGMTDAETERTAELLKSLAGK---------HSVVVVEHdmefvrqIARKVTVLHQGSV 228

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

37-229

9.53e-20

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 85.75 E-value: 9.53e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVlydgedirtipDRELRRRMQIVFQdpggsmnprmsvR 116
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-----------RRAGGARVAYVPQ------------R 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGE--PLQVNRLAE-------------GAELTQKVADVLDSVGLKREHMNRFpHEFSGGQKQRLALARALSLDPEFIL 181
Cdd:NF040873  64 SEVPDslPLTVRDLVAmgrwarrglwrrlTRDDRAAVDDALERVGLADLAGRQL-GELSGGQRQRALLAQGLAQEADLLL 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 663511184 182 LDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRV 229
Cdd:NF040873 143 LDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189

PRK13538

cytochrome c biogenesis heme-transporting ATPase CcmA;

39-235

2.32e-19

cytochrome c biogenesis heme-transporting ATPase CcmA;

Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 84.86 E-value: 2.32e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDrELRRRMQIVFQDPGgsMNPRMSVRsi 118
Cdd:PRK13538  18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRD-EYHQDLLYLGHQPG--IKTELTAL-- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 119 vgEPLQVN-RLAEGAElTQKVADVLDSVGLK-REHMnrfP-HEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:PRK13538  93 --ENLRFYqRLHGPGD-DEALWEALAQVGLAgFEDV---PvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVA 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 663511184 196 QVLNLLEEIQEKLGLTfVFITHALnvVNHISDRVAVMYLG 235
Cdd:PRK13538 167 RLEALLAQHAEQGGMV-ILTTHQD--LPVASDKVRKLRLG 203

PRK13537

nodulation factor ABC transporter ATP-binding protein NodI;

38-239

3.96e-19

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 86.40 E-value: 3.96e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEdirTIPDRELRRRMQIVFQDPGGSMNPRMSVRs 117
Cdd:PRK13537  23 VDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGE---PVPSRARHARQRVGVVPQFDNLDPDFTVR- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 118 ivgEPLQVNRLAEG---AELTQKVADVLDSVGLKREHMNRFpHEFSGGQKQRLALARALSLDPEFILLDEPTSALDvsVQ 194
Cdd:PRK13537  99 ---ENLLVFGRYFGlsaAAARALVPPLLEFAKLENKADAKV-GELSGGMKRRLTLARALVNDPDVLVLDEPTTGLD--PQ 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 663511184 195 AQVLnLLEEIQEKL--GLTFVFITHALNVVNHISDRVAVMYLG-KIVE 239
Cdd:PRK13537 173 ARHL-MWERLRSLLarGKTILLTTHFMEEAERLCDRLCVIEEGrKIAE 219

PRK10895

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

36-238

4.18e-19

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 85.33 E-value: 4.18e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRElRRRMQIVFQDPGGSMNPRMSV 115
Cdd:PRK10895  17 RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHA-RARRGIGYLPQEASIFRRLSV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPLQVNRLAEGAELTQKVADVLDSVGLkrEHM-NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:PRK10895  96 YDNLMAVLQIRDDLSAEQREDRANELMEEFHI--EHLrDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISV 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 663511184 195 AQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK10895 174 IDIKRIIEHLRDS-GLGVLITDHNVRETLAVCERAYIVSQGHLI 216

ABCG_White

cd03234

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...

35-238

4.56e-19

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.

Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 84.63 E-value: 4.56e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTL-----GRVLLGliPITDGSVLYDGEDIRtiPDrELRRRMQIVFQDpgGSM 109
Cdd:cd03234   20 ARILNDVSLHVESGQVMAILGSSGSGKTTLldaisGRVEGG--GTTSGQILFNGQPRK--PD-QFQKCVAYVRQD--DIL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 110 NPRMSVRsivgEPLQ-VNRLAEGAELTQKVADVLD-SVGLKREHMNRFPHEF----SGGQKQRLALARALSLDPEFILLD 183
Cdd:cd03234   93 LPGLTVR----ETLTyTAILRLPRKSSDAIRKKRVeDVLLRDLALTRIGGNLvkgiSGGERRRVSIAVQLLWDPKVLILD 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 184 EPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03234  169 EPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIV 223

BtuD

COG4138

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...

28-238

6.61e-19

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];

Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 84.89 E-value: 6.61e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  28 LSEVKIHVRaVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPiTDGSVLYDGEDIRTIPDRELRRR-----MQivf 102
Cdd:COG4138    3 LNDVAVAGR-LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDWSAAELARHraylsQQ--- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 103 QDPGGSMnPrmsvrsiVGEPLQVNRLAEG--AELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARAL-----SL 175
Cdd:COG4138   78 QSPPFAM-P-------VFQYLALHQPAGAssEAVEQLLAQLAEALGLE-DKLSRPLTQLSGGEWQRVRLAAVLlqvwpTI 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 176 DPE--FILLDEPTSALDVSVQAQVLNLLEEIQEkLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:COG4138  149 NPEgqLLLLDEPMNSLDVAQQAALDRLLRELCQ-QGITVVMSSHDLNHTLRHADRVWLLKQGKLV 212

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

35-269

8.54e-19

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 87.17 E-value: 8.54e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGL--IPITDGSVLY----------------DGE------------ 84
Cdd:TIGR03269  13 KEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIIYhvalcekcgyverpskVGEpcpvcggtlepe 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   85 --DIRTIPD---RELRRRMQIVFQDPGGSMNPRMSVRSIVGEPLQVNRlaEGAELTQKVADVLDSVGLkrEH-MNRFPHE 158
Cdd:TIGR03269  93 evDFWNLSDklrRRIRKRIAIMLQRTFALYGDDTVLDNVLEALEEIGY--EGKEAVGRAVDLIEMVQL--SHrITHIARD 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  159 FSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:TIGR03269 169 LSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAIWLENGEIK 248

                         250       260       270
                  ....*....|....*....|....*....|.
gi 663511184  239 EIANTADLFDKpahpythaLMSAIPEPSLEK 269
Cdd:TIGR03269 249 EEGTPDEVVAV--------FMEGVSEVEKEC 271

PRK10575

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

48-266

9.87e-19

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 84.45 E-value: 9.87e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  48 GETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQD-PGGSmnpRMSVRSIVG---EPL 123
Cdd:PRK10575  37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQlPAAE---GMTVRELVAigrYPW 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 124 Q--VNRLaeGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLL 201
Cdd:PRK10575 114 HgaLGRF--GAADREKVEEAISLVGLK-PLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALV 190

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184 202 EEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDKPAHPYTHAL-MSAIPEPS 266
Cdd:PRK10575 191 HRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGETLEQIYGIpMGILPHPA 256

ycf16

CHL00131

sulfate ABC transporter protein; Validated

40-239

1.04e-18

sulfate ABC transporter protein; Validated

Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 84.31 E-value: 1.04e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLiP---ITDGSVLYDGEDIRTIpDRELRRRMQI--VFQDP---GGSMNP 111
Cdd:CHL00131  25 GLNLSINKGEIHAIMGPNGSGKSTLSKVIAGH-PaykILEGDILFKGESILDL-EPEERAHLGIflAFQYPieiPGVSNA 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 RM------SVRSIVGEPlQVNRLaegaELTQKVADVLDSVGLKREHMNRFPHE-FSGGQKQRLALARALSLDPEFILLDE 184
Cdd:CHL00131 103 DFlrlaynSKRKFQGLP-ELDPL----EFLEIINEKLKLVGMDPSFLSRNVNEgFSGGEKKRNEILQMALLDSELAILDE 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 185 PTSALDVS---VQAQVLNLLEEiQEKlglTFVFITHALNVVNHIS-DRVAVMYLGKIVE 239
Cdd:CHL00131 178 TDSGLDIDalkIIAEGINKLMT-SEN---SIILITHYQRLLDYIKpDYVHVMQNGKIIK 232

PRK10762

D-ribose transporter ATP binding protein; Provisional

38-237

1.17e-18

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 86.98 E-value: 1.17e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDR-----------ELRRRMQIVFqdpG 106
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQdglangivyisEDRKRDGLVL---G 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNPRMSV---RSIVGEPLQVNRLAEgaelTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLD 183
Cdd:PRK10762 345 MSVKENMSLtalRYFSRAGGSLKHADE----QQAVSDFIRLFNIKTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILD 420

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 663511184 184 EPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:PRK10762 421 EPTRGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGRI 473

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

41-237

1.67e-18

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 86.26 E-value: 1.67e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRtipDRELRRRMQ--IVF-----QDPGGSMNPRM 113
Cdd:PRK15439 282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEIN---ALSTAQRLArgLVYlpedrQSSGLYLDAPL 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 S--VRSIVGE--PLQVNRLAEGAELTQKVAdvldSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSAL 189
Cdd:PRK15439 359 AwnVCALTHNrrGFWIKPARENAVLERYRR----ALNIKFNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGV 434

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 663511184 190 DVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:PRK15439 435 DVSARNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGEI 481

MK0520

COG2401

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...

28-240

2.98e-18

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];

Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 82.31 E-value: 2.98e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  28 LSEVKIHVRavDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDgedirtIPDRELRRRMQIVFQ-DPG 106
Cdd:COG2401   38 LRVVERYVL--RDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCVD------VPDNQFGREASLIDAiGRK 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNPRMSVRSIVGeplqvnrlaegaeltqkvadvLDSVGLKRehmnRFPHEFSGGQKQRLALARALSLDPEFILLDEPT 186
Cdd:COG2401  110 GDFKDAVELLNAVG---------------------LSDAVLWL----RRFKELSTGQKFRFRLALLLAERPKLLVIDEFC 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 187 SALDVSVqAQVL--NLLEEIQeKLGLTFVFITHALNVVNHIS-DRVAVMYLGKIVEI 240
Cdd:COG2401  165 SHLDRQT-AKRVarNLQKLAR-RAGITLVVATHHYDVIDDLQpDLLIFVGYGGVPEE 219

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

37-270

3.84e-18

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 85.95 E-value: 3.84e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTiPDRELRRR---MQIVFqdpggsmnprm 113
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDA-GDIATRRRvgyMSQAF----------- 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 svrSIVGEpLQV--N-----RL--AEGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDE 184
Cdd:NF033858 349 ---SLYGE-LTVrqNlelhaRLfhLPAAEIAARVAEMLERFDL-ADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDE 423

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 185 PTSALDVSVQAQVLNLLEEIQEKLGLTfVFI-THALNVVNHiSDRVAVMYLGKIVEIantadlfDKPAhpythALMSAIP 263
Cdd:NF033858 424 PTSGVDPVARDMFWRLLIELSREDGVT-IFIsTHFMNEAER-CDRISLMHAGRVLAS-------DTPA-----ALVAARG 489


                 ....*..
gi 663511184 264 EPSLEKA 270
Cdd:NF033858 490 AATLEEA 496

PRK10790

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

53-249

4.83e-18

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 85.15 E-value: 4.83e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  53 IVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSMNPRMSV-RSIVGEPL-QVNR 127
Cdd:PRK10790 372 LVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQGVAMVQQDPvvlADTFLANVTLgRDISEEQVwQALE 451

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 128 LAEGAELTQKVADVLDS-VGlkrEHMNRfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQE 206
Cdd:PRK10790 452 TVQLAELARSLPDGLYTpLG---EQGNN----LSVGQKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVRE 524

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 663511184 207 KlgLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDK 249
Cdd:PRK10790 525 H--TTLVVIAHRLSTIVE-ADTILVLHRGQAVEQGTHQQLLAA 564

ABCG_EPDR

cd03213

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...

38-238

5.32e-18

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.

Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 81.06 E-value: 5.32e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLI--PITDGSVLYDGediRTIPDRELRRRMQIVFQDpgGSMNPRMSV 115
Cdd:cd03213   25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRtgLGVSGEVLING---RPLDKRSFRKIIGYVPQD--DILHPTLTV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RsivgEPLQVNrlaegAELTqkvadvldsvGLkrehmnrfphefSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:cd03213  100 R----ETLMFA-----AKLR----------GL------------SGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSAL 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 663511184 196 QVLNLLEEIQeKLGLTFVFITHAL-NVVNHISDRVAVMYLGKIV 238
Cdd:cd03213  149 QVMSLLRRLA-DTGRTIICSIHQPsSEIFELFDKLLLLSQGRVI 191

PRK13536

nodulation factor ABC transporter ATP-binding protein NodI;

38-239

6.97e-18

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 83.34 E-value: 6.97e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEdirTIPD--RELRRRMQIVFQ----DPGGSMNP 111
Cdd:PRK13536  57 VNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGV---PVPAraRLARARIGVVPQfdnlDLEFTVRE 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 112 ---------RMSVRSIvgEPLqVNRLAEGAELTQKvADVLDSvglkrehmnrfphEFSGGQKQRLALARALSLDPEFILL 182
Cdd:PRK13536 134 nllvfgryfGMSTREI--EAV-IPSLLEFARLESK-ADARVS-------------DLSGGMKRRLTLARALINDPQLLIL 196

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 183 DEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLG-KIVE 239
Cdd:PRK13536 197 DEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGrKIAE 253

PLN03130

ABC transporter C family member; Provisional

40-246

2.92e-17

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 83.25 E-value: 2.92e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSMnpRMSVr 116
Cdd:PLN03130 1257 GLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKVLGIIPQAPvlfSGTV--RFNL- 1333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  117 sivgEPLQVNRLAEGAELTQK--VADVL--DSVGLKREhMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:PLN03130 1334 ----DPFNEHNDADLWESLERahLKDVIrrNSLGLDAE-VSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDVR 1408

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 663511184  193 VQAQVLNLLEEiqEKLGLTFVFITHALNVVnhI-SDRVAVMYLGKIVEIANTADL 246
Cdd:PLN03130 1409 TDALIQKTIRE--EFKSCTMLIIAHRLNTI--IdCDRILVLDAGRVVEFDTPENL 1459

ABCF_EF-3

cd03221

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...

39-232

5.14e-17

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.

Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 76.72 E-value: 5.14e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGedirtipdrelrrrmqivfqdpggsmnprmsvrsi 118
Cdd:cd03221   17 KDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGS----------------------------------- 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 119 vgeplqvnrlaegaelTQKVAdvldsvglkrehmnRFPHeFSGGQKQRLALARALSLDPEFILLDEPTSALDV-SVQAqv 197
Cdd:cd03221   62 ----------------TVKIG--------------YFEQ-LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLeSIEA-- 108

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 663511184 198 lnLLEEIQEKLGlTFVFITHALNVVNHISDRVAVM 232
Cdd:cd03221  109 --LEEALKEYPG-TVILVSHDRYFLDQVATKIIEL 140

PRK13549

xylose transporter ATP-binding subunit; Provisional

8-237

5.80e-17

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 81.90 E-value: 5.80e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   8 GKVLIEVKGMKKWFPikggmlseVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP-ITDGSVLYDGE-- 84
Cdd:PRK13549 256 GEVILEVRNLTAWDP--------VNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKpv 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  85 DIRTIPDR---------ELRRRMQIVfqdpggsmnPRMSV-RSIVGEPLQ----VNRLAEGAELTQkvadVLDSVglKRE 150
Cdd:PRK13549 328 KIRNPQQAiaqgiamvpEDRKRDGIV---------PVMGVgKNITLAALDrftgGSRIDDAAELKT----ILESI--QRL 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 151 HMnRFPHEF------SGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNH 224
Cdd:PRK13549 393 KV-KTASPElaiarlSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLG 470

                        250
                 ....*....|...
gi 663511184 225 ISDRVAVMYLGKI 237
Cdd:PRK13549 471 LSDRVLVMHEGKL 483

PRK09984

phosphonate ABC transporter ATP-binding protein;

28-237

1.21e-16

phosphonate ABC transporter ATP-binding protein;

Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 78.52 E-value: 1.21e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  28 LSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP----------ITDGSVLYDGEDIRTIpdRELRRR 97
Cdd:PRK09984  10 LAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITgdksagshieLLGRTVQREGRLARDI--RKSRAN 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  98 MQIVFQDpgGSMNPRMSVRSIV------GEPLQVNRLAEGAEL-TQKVADVLDSVGlkrehMNRFPHE----FSGGQKQR 166
Cdd:PRK09984  88 TGYIFQQ--FNLVNRLSVLENVligalgSTPFWRTCFSWFTREqKQRALQALTRVG-----MVHFAHQrvstLSGGQQQR 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 663511184 167 LALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:PRK09984 161 VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHV 231

hmuV

PRK13547

heme ABC transporter ATP-binding protein;

34-252

1.28e-16

heme ABC transporter ATP-binding protein;

Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 78.72 E-value: 1.28e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  34 HVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIP---------ITdGSVLYDGEDIRTIPDRELRRRMQIVFQ- 103
Cdd:PRK13547  13 HRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTgggaprgarVT-GDVTLNGEPLAAIDAPRLARLRAVLPQa 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 104 -DPGGSMnprmSVRSIV--GEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALS------ 174
Cdd:PRK13547  92 aQPAFAF----SAREIVllGRYPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLAqlwpph 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 175 ---LDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFdKPA 251
Cdd:PRK13547 168 daaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVL-TPA 246


                 .
gi 663511184 252 H 252
Cdd:PRK13547 247 H 247

3a01204

TIGR00955

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...

10-275

1.95e-16

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 80.48 E-value: 1.95e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   10 VLIEVKGMKKWFPIKGGMLSEVKIHVRAVDGVdlqIKRGETLGIVGESGCGKTTLGRVLLGLIP---ITDGSVLYDGedi 86
Cdd:TIGR00955  16 QDGSWKQLVSRLRGCFCRERPRKHLLKNVSGV---AKPGELLAVMGSSGAGKTTLMNALAFRSPkgvKGSGSVLLNG--- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   87 RTIPDRELRRRMQIVFQDpggSMN-PRMSVRsivgEPLQVN-RLAEGAELTQK-----VADVLDSVGLKREHMNRFPHE- 158
Cdd:TIGR00955  90 MPIDAKEMRAISAYVQQD---DLFiPTLTVR----EHLMFQaHLRMPRRVTKKekrerVDEVLQALGLRKCANTRIGVPg 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  159 ----FSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNV-VNHISDRVAVMY 233
Cdd:TIGR00955 163 rvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQK-GKTIICTIHQPSSeLFELFDKIILMA 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 663511184  234 LGKIV---EIANTADLFDKPAHP----YTHA--LMSAIPE-PSLEKASRERI 275
Cdd:TIGR00955 242 EGRVAylgSPDQAVPFFSDLGHPcpenYNPAdfYVQVLAViPGSENESRERI 293

PRK11147

ABC transporter ATPase component; Reviewed

39-217

2.64e-16

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 79.99 E-value: 2.64e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTipdrelrrRMQivfQDPggsmnPRM---SV 115
Cdd:PRK11147  20 DNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVA--------RLQ---QDP-----PRNvegTV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPLQ------------------------VNRLAE---------GAELTQKVADVLDSVGLKREHMnrfPHEFSGG 162
Cdd:PRK11147  84 YDFVAEGIEeqaeylkryhdishlvetdpseknLNELAKlqeqldhhnLWQLENRINEVLAQLGLDPDAA---LSSLSGG 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 163 QKQRLALARALSLDPEFILLDEPTSALDVsvqaQVLNLLEEIQEKLGLTFVFITH 217
Cdd:PRK11147 161 WLRKAALGRALVSNPDVLLLDEPTNHLDI----ETIEWLEGFLKTFQGSIIFISH 211

ABCC_SUR2

cd03288

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...

27-260

3.42e-16

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 77.26 E-value: 3.42e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  27 MLSEVKIHVRAVdgvdlqIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP- 105
Cdd:cd03288   32 NLKPVLKHVKAY------IKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPi 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 106 --GGSMNPRMSVRSIVGEplqvNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLD 183
Cdd:cd03288  106 lfSGSIRFNLDPECKCTD----DRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMD 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 184 EPTSALDVSVQaqvlNLLEEI--QEKLGLTFVFITHAlnvVNHI--SDRVAVMYLGKIVEIANTADLFDKPAHPYTHALM 259
Cdd:cd03288  182 EATASIDMATE----NILQKVvmTAFADRTVVTIAHR---VSTIldADLVLVLSRGILVECDTPENLLAQEDGVFASLVR 254


                 .
gi 663511184 260 S 260
Cdd:cd03288  255 T 255

PLN03232

ABC transporter C family member; Provisional

25-264

3.44e-16

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 80.02 E-value: 3.44e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   25 GGMLSEVKIHVR-------AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRR 97
Cdd:PLN03232 1232 RGSIKFEDVHLRyrpglppVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRV 1311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   98 MQIVFQDP---GGSMnpRMSVrsivgEPLQVNRLAEGAELTQK--VADVLD--SVGLKREhMNRFPHEFSGGQKQRLALA 170
Cdd:PLN03232 1312 LSIIPQSPvlfSGTV--RFNI-----DPFSEHNDADLWEALERahIKDVIDrnPFGLDAE-VSEGGENFSVGQRQLLSLA 1383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  171 RALSLDPEFILLDEPTSALDVSVQAQVLNLLEEiqEKLGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:PLN03232 1384 RALLRRSKILVLDEATASVDVRTDSLIQRTIRE--EFKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRD 1460

                         250
                  ....*....|....
gi 663511184  251 AHPYTHALMSAIPE 264
Cdd:PLN03232 1461 TSAFFRMVHSTGPA 1474

ABC_RNaseL_inhibitor_domain2

cd03237

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

45-231

3.68e-16

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 77.06 E-value: 3.68e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  45 IKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDI-----RTIPDRELRRRMQIVFQDPGGSMNPRMsvRSIV 119
Cdd:cd03237   22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVsykpqYIKADYEGTVRDLLSSITKDFYTHPYF--KTEI 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 120 GEPLQVNRLaegaeltqkvadvldsvglkrehMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLN 199
Cdd:cd03237  100 AKPLQIEQI-----------------------LDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASK 156

                        170       180       190
                 ....*....|....*....|....*....|..
gi 663511184 200 LLEEIQEKLGLTFVFITHALNVVNHISDRVAV 231
Cdd:cd03237  157 VIRRFAENNEKTAFVVEHDIIMIDYLADRLIV 188

ABC_CcmA_heme_exporter

cd03231

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...

36-201

4.87e-16

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.

Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 75.61 E-value: 4.87e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAV-DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDrELRRRMQIVFQDPGgsMNPRMS 114
Cdd:cd03231   13 RALfSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRD-SIARGLLYLGHAPG--IKTTLS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRsivgEPLQVNRLAEGaelTQKVADVLDSVGLKR-EHmnRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:cd03231   90 VL----ENLRFWHADHS---DEQVEEALARVGLNGfED--RPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAG 160


                 ....*...
gi 663511184 194 QAQVLNLL 201
Cdd:cd03231  161 VARFAEAM 168

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

37-237

5.88e-16

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 79.67 E-value: 5.88e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTipdrelrrRMQIVFQDPGgsMNPRMSV- 115
Cdd:TIGR01257  945 AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIET--------NLDAVRQSLG--MCPQHNIl 1014

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   116 --RSIVGEPLQV-----NRLAEGAELTQKVadVLDSVGLKREHmNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSA 188
Cdd:TIGR01257 1015 fhHLTVAEHILFyaqlkGRSWEEAQLEMEA--MLEDTGLHHKR-NEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSG 1091

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 663511184   189 LDVSVQAQVLNLLeeIQEKLGLTFVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:TIGR01257 1092 VDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRL 1138

znuC

PRK09544

high-affinity zinc transporter ATPase; Reviewed

36-229

7.19e-16

high-affinity zinc transporter ATPase; Reviewed

Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 76.31 E-value: 7.19e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  36 RAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVlydgedirtipDRELRRRMQIVFQDPggSMNPRMsv 115
Cdd:PRK09544  18 RVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI-----------KRNGKLRIGYVPQKL--YLDTTL-- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 rsivgePLQVNRLAEGAELTQKvADVLDSvgLKR---EHMNRFP-HEFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:PRK09544  83 ------PLTVNRFLRLRPGTKK-EDILPA--LKRvqaGHLIDAPmQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDV 153

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 663511184 192 SVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRV 229
Cdd:PRK09544 154 NGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEV 191

PRK10789

SmdA family multidrug ABC transporter permease/ATP-binding protein;

37-250

1.21e-15

SmdA family multidrug ABC transporter permease/ATP-binding protein;

Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 77.83 E-value: 1.21e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggsmnprMSVR 116
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVSQTP-------FLFS 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGEPLQVNRLAEGAELTQKVADvLDSVglkREHMNRFPHEF-----------SGGQKQRLALARALSLDPEFILLDEP 185
Cdd:PRK10789 403 DTVANNIALGRPDATQQEIEHVAR-LASV---HDDILRLPQGYdtevgergvmlSGGQKQRISIARALLLNAEILILDDA 478

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 186 TSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:PRK10789 479 LSAVDGRTEHQILHNLRQWGE--GRTVIISAHRLSALTE-ASEILVMQHGHIAQRGNHDQLAQQS 540

ABCC_SUR1_N

cd03290

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...

41-232

1.28e-15

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 75.06 E-value: 1.28e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDG--EDIRTIPDRELRRRMQIVF--QDPGgSMNPRMSVR 116
Cdd:cd03290   20 INIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNknESEPSFEATRSRNRYSVAYaaQKPW-LLNATVEEN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGEPLQvnrlaegaelTQKVADVLDSVGLKREhMNRFPH-----------EFSGGQKQRLALARALSLDPEFILLDEP 185
Cdd:cd03290   99 ITFGSPFN----------KQRYKAVTDACSLQPD-IDLLPFgdqteigergiNLSGGQRQRICVARALYQNTNIVFLDDP 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 663511184 186 TSALDVSV-----QAQVLNLLEEIQEklglTFVFITHALNVVNHiSDRVAVM 232
Cdd:cd03290  168 FSALDIHLsdhlmQEGILKFLQDDKR----TLVLVTHKLQYLPH-ADWIIAM 214

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

2-231

1.85e-15

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 77.54 E-value: 1.85e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   2 TEESRDGKVLIEVKGMKKwfpikggMLSEVKIHVRAvdGvdlQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLY 81
Cdd:PRK13409 331 PRDESERETLVEYPDLTK-------KLGDFSLEVEG--G---EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDP 398

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  82 DgEDIRTIPdrelrrrmQIVFQDPGG-------SMNPRMS---VRSIVGEPLQVNRLaegaeLTQKVADVldsvglkreh 151
Cdd:PRK13409 399 E-LKISYKP--------QYIKPDYDGtvedllrSITDDLGssyYKSEIIKPLQLERL-----LDKNVKDL---------- 454

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 152 mnrfphefSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAV 231
Cdd:PRK13409 455 --------SGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHDIYMIDYISDRLMV 526

PRK15056

manganese/iron ABC transporter ATP-binding protein;

37-247

1.99e-15

manganese/iron ABC transporter ATP-binding protein;

Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 75.30 E-value: 1.99e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVlydgeDIRTIPDRELRRRMQIVFQDPGGSMNPRMSVr 116
Cdd:PRK15056  22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKI-----SILGQPTRQALQKNLVAYVPQSEEVDWSFPV- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 sIVGEPLQVNRLAE-------GAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSAL 189
Cdd:PRK15056  96 -LVEDVVMMGRYGHmgwlrraKKRDRQIVTAALARVDMV-EFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGV 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 190 DVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDrVAVMYLGKIVEIANTADLF 247
Cdd:PRK15056 174 DVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCD-YTVMVKGTVLASGPTETTF 229

PTZ00243

ABC transporter; Provisional

40-246

2.38e-15

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 77.51 E-value: 2.38e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   40 GVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP----GgsmnprmSV 115
Cdd:PTZ00243 1328 GVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRELRRQFSMIPQDPvlfdG-------TV 1400

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  116 RSIVGEPLQvnrlAEGAEltqkVADVLDSVGLkREHMNRFPH-----------EFSGGQKQRLALARA-LSLDPEFILLD 183
Cdd:PTZ00243 1401 RQNVDPFLE----ASSAE----VWAALELVGL-RERVASESEgidsrvleggsNYSVGQRQLMCMARAlLKKGSGFILMD 1471

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184  184 EPTS----ALDVSVQAQVLNLLEeiqeklGLTFVFITHALNVVNHIsDRVAVMYLGKIVEIANTADL 246
Cdd:PTZ00243 1472 EATAnidpALDRQIQATVMSAFS------AYTVITIAHRLHTVAQY-DKIIVMDHGAVAEMGSPREL 1531

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

38-249

4.17e-15

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 76.91 E-value: 4.17e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEdIRTIPDrelrrrmQIVFQdpggsmNPRMSVRS 117
Cdd:TIGR00957  654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS-VAYVPQ-------QAWIQ------NDSLRENI 719

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   118 IVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQV 197
Cdd:TIGR00957  720 LFGKALNEKYYQQVLEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHI 799

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184   198 lnlLEEIQEKLGL----TFVFITHALNVVNHIsDRVAVMYLGKIVEIANTADLFDK 249
Cdd:TIGR00957  800 ---FEHVIGPEGVlknkTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQR 851

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

44-231

5.64e-15

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 75.98 E-value: 5.64e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  44 QIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVlydGEDIRT-------IPDRELRRR---MQIVFQDPGGSMnprm 113
Cdd:COG1245  362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEV---DEDLKIsykpqyiSPDYDGTVEeflRSANTDDFGSSY---- 434

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 sVRSIVGEPLQVNRLaegaeLTQKVADVldsvglkrehmnrfphefSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:COG1245  435 -YKTEIIKPLGLEKL-----LDKNVKDL------------------SGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQ 490

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 663511184 194 QAQVLNLLEEIQEKLGLTFVFITHALNVVNHISDRVAV 231
Cdd:COG1245  491 RLAVAKAIRRFAENRGKTAMVVDHDIYLIDYISDRLMV 528

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

28-238

6.11e-15

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 75.72 E-value: 6.11e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  28 LSEVKIHVRAVDG------VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE--DIRTIPDR------- 92
Cdd:PRK11288 253 LGEVRLRLDGLKGpglrepISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKpiDIRSPRDAiragiml 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  93 --ELRRRMQIVfqdPGGSM--NPRMSVR---SIVGEPLQVNRLAEGAELTqkvadvLDSVGLKREHMNRFPHEFSGGQKQ 165
Cdd:PRK11288 333 cpEDRKAEGII---PVHSVadNINISARrhhLRAGCLINNRWEAENADRF------IRSLNIKTPSREQLIMNLSGGNQQ 403

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 663511184 166 RLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK11288 404 KAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQ-GVAVLFVSSDLPEVLGVADRIVVMREGRIA 475

PRK10762

D-ribose transporter ATP binding protein; Provisional

9-236

7.00e-15

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 75.43 E-value: 7.00e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   9 KVLIEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRt 88
Cdd:PRK10762   2 QALLQLKGIDKAFP-----------GVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVT- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  89 ipdrelrrrmqivFQDPGGSMNPRMSvrsIVGEPLqvNRLAE---------GAELTQKV-----------ADVLdsvgLK 148
Cdd:PRK10762  70 -------------FNGPKSSQEAGIG---IIHQEL--NLIPQltiaeniflGREFVNRFgridwkkmyaeADKL----LA 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 149 REHMNRFPH----EFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNH 224
Cdd:PRK10762 128 RLNLRFSSDklvgELSIGEQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFE 206

                        250
                 ....*....|..
gi 663511184 225 ISDRVAVMYLGK 236
Cdd:PRK10762 207 ICDDVTVFRDGQ 218

PRK03695

vitamin B12-transporter ATPase; Provisional

44-238

2.11e-14

vitamin B12-transporter ATPase; Provisional

Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 71.89 E-value: 2.11e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  44 QIKRGETLGIVGESGCGKTTLGRVLLGLIPiTDGSVLYDGEDIRTIPDREL-RRRMQIVFQDPGGSMNP--------RMS 114
Cdd:PRK03695  18 EVRAGEILHLVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEAWSAAELaRHRAYLSQQQTPPFAMPvfqyltlhQPD 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVNRLAEGAELTQKvadvldsvglkrehMNRFPHEFSGGQKQRLALARAL-----SLDPE--FILLDEPTS 187
Cdd:PRK03695  97 KTRTEAVASALNEVAEALGLDDK--------------LGRSVNQLSGGEWQRVRLAAVVlqvwpDINPAgqLLLLDEPMN 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 663511184 188 ALDVSVQAQVLNLLEEIQEkLGLTFVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:PRK03695 163 SLDVAQQAALDRLLSELCQ-QGIAVVMSSHDLNHTLRHADRVWLLKQGKLL 212

sufC

PRK09580

cysteine desulfurase ATPase component; Reviewed

27-239

3.70e-14

cysteine desulfurase ATPase component; Reviewed

Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 71.36 E-value: 3.70e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  27 MLSEVKIHVRAVD-----GVDLQIKRGETLGIVGESGCGKTTLGRVLLGL--IPITDGSVLYDGEDIRTI-PDRELRRRM 98
Cdd:PRK09580   1 MLSIKDLHVSVEDkailrGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGRedYEVTGGTVEFKGKDLLELsPEDRAGEGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  99 QIVFQDP------------GGSMNprmSVRSIVG-EPLQ----VNRLAEGAELTQKVADVLD-SVGLKrehmnrfpheFS 160
Cdd:PRK09580  81 FMAFQYPveipgvsnqfflQTALN---AVRSYRGqEPLDrfdfQDLMEEKIALLKMPEDLLTrSVNVG----------FS 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 161 GGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHIS-DRVAVMYLGKIVE 239
Cdd:PRK09580 148 GGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDG-KRSFIIVTHYQRILDYIKpDYVHVLYQGRIVK 226

PvdE

COG4615

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...

41-184

3.98e-14

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];

Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 73.29 E-value: 3.98e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIrTIPDRE-LRRRMQIVFQD-------PGGSMNPr 112
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPV-TADNREaYRQLFSAVFSDfhlfdrlLGLDGEA- 428

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184 113 msvrsivgEPLQVNRLAEGAELTQKVA---DVLDSVGLkrehmnrfphefSGGQKQRLALARALSLDPEFILLDE 184
Cdd:COG4615  429 --------DPARARELLERLELDHKVSvedGRFSTTDL------------SQGQRKRLALLVALLEDRPILVFDE 483

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

38-246

5.95e-14

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 72.51 E-value: 5.95e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIR-TIPDRELRRRMQIVFQD-------PGGSM 109
Cdd:PRK09700 279 VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISpRSPLDAVKKGMAYITESrrdngffPNFSI 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 110 NPRMSV-RSIVGEPLQ--VNRLAEGAEltQKVADVL-DSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEP 185
Cdd:PRK09700 359 AQNMAIsRSLKDGGYKgaMGLFHEVDE--QRTAENQrELLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEP 436

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184 186 TSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEI-ANTADL 246
Cdd:PRK09700 437 TRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQIlTNRDDM 497

3a01203

TIGR00954

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...

44-217

9.43e-14

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 72.47 E-value: 9.43e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   44 QIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGsvlydgedIRTIPDRelrrrmQIVFQDPggsMNPRMSVRSI---VG 120
Cdd:TIGR00954 474 EVPSGNNLLICGPNGCGKSSLFRILGELWPVYGG--------RLTKPAK------GKLFYVP---QRPYMTLGTLrdqII 536

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  121 EPLQVNRLAEGAELTQKVADVLDSVGL----KRE----HMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:TIGR00954 537 YPDSSEDMKRRGLSDKDLEQILDNVQLthilEREggwsAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVD 616

                         170       180
                  ....*....|....*....|....*
gi 663511184  193 VQAQVLNLLEEIqeklGLTFVFITH 217
Cdd:TIGR00954 617 VEGYMYRLCREF----GITLFSVSH 637

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

1-282

1.60e-13

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 71.24 E-value: 1.60e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   1 MTEESRDGKVLIEVKGMKKWFpikGGmlsevkihVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVL 80
Cdd:PRK15439   1 MQTSDTTAPPLLCARSISKQY---SG--------VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLE 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  81 YDGEDI-RTIPDRELRRRMQIVFQDPggSMNPRMSVRSIVgeplqVNRLAEGAELTQKVADVLDSVGLkreHMNrfPHEF 159
Cdd:PRK15439  70 IGGNPCaRLTPAKAHQLGIYLVPQEP--LLFPNLSVKENI-----LFGLPKRQASMQKMKQLLAALGC---QLD--LDSS 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 160 SG----GQKQRLALARALSLDPEFILLDEPTSALdvsVQAQVLNLLEEIQE--KLGLTFVFITHALNVVNHISDRVAVMY 233
Cdd:PRK15439 138 AGslevADRQIVEILRGLMRDSRILILDEPTASL---TPAETERLFSRIREllAQGVGIVFISHKLPEIRQLADRISVMR 214

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 663511184 234 LGKIVEIANTADLFDKpahpythALMSAIPEPSLEKASRERIVLSGDVP 282
Cdd:PRK15439 215 DGTIALSGKTADLSTD-------DIIQAITPAAREKSLSASQKLWLELP 256

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

35-190

4.12e-13

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 70.54 E-value: 4.12e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLgrvlLGLIP----ITDGSVLYDGEDIRtipDRELRRRM--QIVF--QDPG 106
Cdd:NF033858  14 TVALDDVSLDIPAGCMVGLIGPDGVGKSSL----LSLIAgarkIQQGRVEVLGGDMA---DARHRRAVcpRIAYmpQGLG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 107 GSMNPRMSVRsivgEPLQ-VNRL--AEGAELTQKVADVLDSVGLKRehmnrFPH----EFSGGQKQRLALARALSLDPEF 179
Cdd:NF033858  87 KNLYPTLSVF----ENLDfFGRLfgQDAAERRRRIDELLRATGLAP-----FADrpagKLSGGMKQKLGLCCALIHDPDL 157

                        170
                 ....*....|.
gi 663511184 180 ILLDEPTSALD 190
Cdd:NF033858 158 LILDEPTTGVD 168

ABCG_PDR_domain1

cd03233

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...

38-238

5.05e-13

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 67.29 E-value: 5.05e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPIT---DGSVLYDGEDIRTIPDRELRrrmQIVFQDPGGSMNPRMS 114
Cdd:cd03233   23 LKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEKYPG---EIIYVSEEDVHFPTLT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRsivgEPLQVNRLAEGaeltqkvadvldsvglkrehmNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:cd03233  100 VR----ETLDFALRCKG---------------------NEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTA 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 663511184 195 AQVLNLLEEIQEKLGLT-FVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:cd03233  155 LEILKCIRTMADVLKTTtFVSLYQASDEIYDLFDKVLVLYEGRQI 199

PLN03232

ABC transporter C family member; Provisional

23-247

1.81e-12

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 68.85 E-value: 1.81e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   23 IKGGMLS-EVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLG-LIPITDGSVLYDGE-----DIRTIPDRELR 95
Cdd:PLN03232  617 IKNGYFSwDSKTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGeLSHAETSSVVIRGSvayvpQVSWIFNATVR 696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   96 RrmQIVFqdpGGSMNPRMSVRSIVGEPLQVN-RLAEGAELTQkvadvldsVGLKREHMnrfphefSGGQKQRLALARALS 174
Cdd:PLN03232  697 E--NILF---GSDFESERYWRAIDVTALQHDlDLLPGRDLTE--------IGERGVNI-------SGGQKQRVSMARAVY 756

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 663511184  175 LDPEFILLDEPTSALDVSVQAQVLN--LLEEIQeklGLTFVFITHALNVVNHIsDRVAVMYLGKIVEIANTADLF 247
Cdd:PLN03232  757 SNSDIYIFDDPLSALDAHVAHQVFDscMKDELK---GKTRVLVTNQLHFLPLM-DRIILVSEGMIKEEGTFAELS 827

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

47-240

1.85e-12

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 64.32 E-value: 1.85e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    47 RGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLY-DGEDIRTIPDRELRRrmqivfqdpggsmnprmsvrsivgeplqv 125
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYiDGEDILEEVLDQLLL----------------------------- 51

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   126 nrlaegaeltqkvadvldsvglkrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVL-----NL 200
Cdd:smart00382  52 ------------------------IIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLlleelRL 107

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 663511184   201 LEEIQEKLGLTFVFITHalnVVNHISDRVAVMYLGKIVEI 240
Cdd:smart00382 108 LLLLKSEKNLTVILTTN---DEKDLGPALLRRRFDRRIVL 144

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

35-276

1.90e-12

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 68.01 E-value: 1.90e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRE-LRRRMQIVFQDPggSMNPRM 113
Cdd:PRK11288  17 VKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAaLAAGVAIIYQEL--HLVPEM 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVrsivGEPLQVNRLAE------GAELTQKVADVLDSVGLKREhmnrfPH----EFSGGQKQRLALARALSLDPEFILLD 183
Cdd:PRK11288  95 TV----AENLYLGQLPHkggivnRRLLNYEAREQLEHLGVDID-----PDtplkYLSIGQRQMVEIAKALARNARVIAFD 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 184 EPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEiantadlfdkpahpyTHalmsaip 263
Cdd:PRK11288 166 EPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVA---------------TF------- 222

                        250
                 ....*....|...
gi 663511184 264 ePSLEKASRERIV 276
Cdd:PRK11288 223 -DDMAQVDRDQLV 234

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

41-246

2.01e-12

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 68.43 E-value: 2.01e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQDP---GGSMNPRMSVRS 117
Cdd:TIGR00957 1305 INVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFKITIIPQDPvlfSGSLRMNLDPFS 1384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   118 IVGEPlQVNRLAEGAELTQKVADVLDsvGLKREhMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVS----V 193
Cdd:TIGR00957 1385 QYSDE-EVWWALELAHLKTFVSALPD--KLDHE-CAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLEtdnlI 1460

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 663511184   194 QAQVLNLLEEIqeklglTFVFITHALNVVNHISdRVAVMYLGKIVEIANTADL 246
Cdd:TIGR00957 1461 QSTIRTQFEDC------TVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNL 1506

PRK10522

multidrug transporter membrane component/ATP-binding component; Provisional

37-240

2.29e-12

multidrug transporter membrane component/ATP-binding component; Provisional

Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 68.07 E-value: 2.29e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRELRRRMQIVFQD---------PGG 107
Cdd:PRK10522 338 SVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDYRKLFSAVFTDfhlfdqllgPEG 417

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 108 SmnprmsvrsiVGEPLQVNRLAEGAELTQKVadvldsvglkREHMNRFPH-EFSGGQKQRLALARALSLDPEFILLDEpt 186
Cdd:PRK10522 418 K----------PANPALVEKWLERLKMAHKL----------ELEDGRISNlKLSKGQKKRLALLLALAEERDILLLDE-- 475

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 187 SALDVSVQAQ---VLNLLEEIQEKlGLTFVFITHALNVVNHiSDRVAVMYLGKIVEI 240
Cdd:PRK10522 476 WAADQDPHFRrefYQVLLPLLQEM-GKTIFAISHDDHYFIH-ADRLLEMRNGQLSEL 530

PLN03130

ABC transporter C family member; Provisional

23-249

2.57e-12

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 68.23 E-value: 2.57e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   23 IKGGMLS-EVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLG-LIPITDGSVLYDGE-----DIRTIPDRELR 95
Cdd:PLN03130  617 IKNGYFSwDSKAERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGeLPPRSDASVVIRGTvayvpQVSWIFNATVR 696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   96 RrmQIVFqdpGGSMNPRMSVRSIVGEPLQVN-RLAEGAELTQkvadvldsvgLKREHMNrfpheFSGGQKQRLALARALS 174
Cdd:PLN03130  697 D--NILF---GSPFDPERYERAIDVTALQHDlDLLPGGDLTE----------IGERGVN-----ISGGQKQRVSMARAVY 756

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  175 LDPEFILLDEPTSALDVSVQAQVLN--LLEEIQEKlglTFVFITHALNVVNHIsDRVAVMYLGKIVE------IANTADL 246
Cdd:PLN03130  757 SNSDVYIFDDPLSALDAHVGRQVFDkcIKDELRGK---TRVLVTNQLHFLSQV-DRIILVHEGMIKEegtyeeLSNNGPL 832


                  ...
gi 663511184  247 FDK 249
Cdd:PLN03130  833 FQK 835

PTZ00265

multidrug resistance protein (mdr1); Provisional

1-224

2.77e-12

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 68.13 E-value: 2.77e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    1 MTEESRDGKVLIEVKGMKkwfpikggmLSEVKIH------VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPI 74
Cdd:PTZ00265  367 LVENNDDGKKLKDIKKIQ---------FKNVRFHydtrkdVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDP 437

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   75 TDGSVLY-DGEDIRTIPDRELRRRMQIVFQDP-----------------------------------GGSMNPRMSVRSI 118
Cdd:PTZ00265  438 TEGDIIInDSHNLKDINLKWWRSKIGVVSQDPllfsnsiknnikyslyslkdlealsnyynedgndsQENKNKRNSCRAK 517

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  119 VGEPLQ-VNRLAEGAELTQ-----------KVADVLDSVgLKREHMNRFPHEF-----------SGGQKQRLALARALSL 175
Cdd:PTZ00265  518 CAGDLNdMSNTTDSNELIEmrknyqtikdsEVVDVSKKV-LIHDFVSALPDKYetlvgsnasklSGGQKQRISIARAIIR 596

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 663511184  176 DPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNH 224
Cdd:PTZ00265  597 NPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAHRLSTIRY 645

PTZ00243

ABC transporter; Provisional

41-250

4.77e-12

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 67.50 E-value: 4.77e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDgedirtipdrelrRRMQIVFQDPGgSMNPrmSVRS--I 118
Cdd:PTZ00243  679 VSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAE-------------RSIAYVPQQAW-IMNA--TVRGniL 742

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  119 VGEPLQVNRLAEGAELTQKVADV-LDSVGLKREhMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQV 197
Cdd:PTZ00243  743 FFDEEDAARLADAVRVSQLEADLaQLGGGLETE-IGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGERV 821

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 663511184  198 LNllEEIQEKL-GLTFVFITHALNVVNHiSDRVAVMYLGKIVEIANTADLFDKP 250
Cdd:PTZ00243  822 VE--ECFLGALaGKTRVLATHQVHVVPR-ADYVVALGDGRVEFSGSSADFMRTS 872

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

37-235

4.84e-12

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 67.35 E-value: 4.84e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTipdrelrrRMQIVFQDPG-----GSMNP 111
Cdd:TIGR01257 1954 AVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILT--------NISDVHQNMGycpqfDAIDD 2025

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   112 RMSVRsivgEPLQVNRLAEG--AELTQKVAD-VLDSVGLKReHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSA 188
Cdd:TIGR01257 2026 LLTGR----EHLYLYARLRGvpAEEIEKVANwSIQSLGLSL-YADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTG 2100

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 663511184   189 LDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLG 235
Cdd:TIGR01257 2101 MDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKG 2146

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

28-233

1.12e-11

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 65.99 E-value: 1.12e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  28 LSEVKIHVRAVDGVDL----QIKRGETLGIVGESGCGKTTLGRVLLG-LIP---ITDGSV-------------------- 79
Cdd:PRK13409  75 LEEEPVHRYGVNGFKLyglpIPKEGKVTGILGPNGIGKTTAVKILSGeLIPnlgDYEEEPswdevlkrfrgtelqnyfkk 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  80 LYDGEdIRTIpdrelrRRMQIVFQDPggsmnprMSVRSIVGEplqvnrLAEGAELTQKVADVLDSVGLkREHMNRFPHEF 159
Cdd:PRK13409 155 LYNGE-IKVV------HKPQYVDLIP-------KVFKGKVRE------LLKKVDERGKLDEVVERLGL-ENILDRDISEL 213

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663511184 160 SGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEklGLTFVFITHALNVVNHISDRVAVMY 233
Cdd:PRK13409 214 SGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQRLNVARLIRELAE--GKYVLVVEHDLAVLDYLADNVHIAY 285

PTZ00265

multidrug resistance protein (mdr1); Provisional

76-231

1.24e-11

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 66.21 E-value: 1.24e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   76 DGSVLYDGEDIRTIPDRELRRRMQIVFQDPggsMNPRMSV---------RSIVGEPLQVNRLAEGAELTQKVADVLDSvg 146
Cdd:PTZ00265 1276 SGKILLDGVDICDYNLKDLRNLFSIVSQEP---MLFNMSIyenikfgkeDATREDVKRACKFAAIDEFIESLPNKYDT-- 1350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  147 lkreHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLTFVFITHALNVVNHiS 226
Cdd:PTZ00265 1351 ----NVGPYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASIKR-S 1425


                  ....*
gi 663511184  227 DRVAV 231
Cdd:PTZ00265 1426 DKIVV 1430

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

28-233

3.00e-11

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 64.42 E-value: 3.00e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  28 LSEVKIHVRAVDGVDL----QIKRGETLGIVGESGCGKTTLGRVLLG-LIP-------------ITD---GSVLYDgeDI 86
Cdd:COG1245   75 LEEDPVHRYGENGFRLyglpVPKKGKVTGILGPNGIGKSTALKILSGeLKPnlgdydeepswdeVLKrfrGTELQD--YF 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  87 RTIPDRELR--RRMQIVFQDPggsmnprMSVRSIVGEplqvnrLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQK 164
Cdd:COG1245  153 KKLANGEIKvaHKPQYVDLIP-------KVFKGTVRE------LLEKVDERGKLDELAEKLGLE-NILDRDISELSGGEL 218

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 165 QRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMY 233
Cdd:COG1245  219 QRVAIAAALLRDADFYFFDEPSSYLDIYQRLNVARLIRELAEE-GKYVLVVEHDLAILDYLADYVHILY 286

PLN03211

ABC transporter G-25; Provisional

38-233

4.38e-11

ABC transporter G-25; Provisional

Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 64.13 E-value: 4.38e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITD--GSVLYDGEDirtiPDRELRRRMQIVFQDpgGSMNPRMSV 115
Cdd:PLN03211  84 LNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRK----PTKQILKRTGFVTQD--DILYPHLTV 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RS--IVGEPLQVNRLAEGAELTQKVADVLDSVGL-KREHM---NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSAL 189
Cdd:PLN03211 158 REtlVFCSLLRLPKSLTKQEKILVAESVISELGLtKCENTiigNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGL 237

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 663511184 190 DVSVQAQVLNLLEEIQEKlGLTFVFITHalnvvnHISDRVAVMY 233
Cdd:PLN03211 238 DATAAYRLVLTLGSLAQK-GKTIVTSMH------QPSSRVYQMF 274

ABC_RNaseL_inhibitor_domain1

cd03236

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

46-233

6.80e-11

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 62.00 E-value: 6.80e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  46 KRGETLGIVGESGCGKTTLGRVLLG-LIPitdGSVLYDGE-DIRTIPDRELRRRMQIVFQD-PGGSMNPRMSVRSIVGEP 122
Cdd:cd03236   24 REGQVLGLVGPNGIGKSTALKILAGkLKP---NLGKFDDPpDWDEILDEFRGSELQNYFTKlLEGDVKVIVKPQYVDLIP 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 123 LQVN----RLAEGAELTQKVADVLDSVGLkREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSvqaQVL 198
Cdd:cd03236  101 KAVKgkvgELLKKKDERGKLDELVDQLEL-RHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIK---QRL 176

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 663511184 199 NLLEEIQE--KLGLTFVFITHALNVVNHISDRVAVMY 233
Cdd:cd03236  177 NAARLIRElaEDDNYVLVVEHDLAVLDYLSDYIHCLY 213

tagH

PRK13545

teichoic acids export protein ATP-binding subunit; Provisional

37-248

2.32e-10

teichoic acids export protein ATP-binding subunit; Provisional

Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 61.83 E-value: 2.32e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVlydgeDIRTipdrelrrrmQIVFQDPGGSMNPRMS-V 115
Cdd:PRK13545  39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTV-----DIKG----------SAALIAISSGLNGQLTgI 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 116 RSIVGEPLQVNRLAEG-AELTQKVADVLDsVGlkrEHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQ 194
Cdd:PRK13545 104 ENIELKGLMMGLTKEKiKEIIPEIIEFAD-IG---KFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFT 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 663511184 195 AQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFD 248
Cdd:PRK13545 180 KKCLDKMNEFKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVD 232

ABC_RNaseL_inhibitor

cd03222

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...

45-233

9.53e-10

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 57.20 E-value: 9.53e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  45 IKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPdrelrrrmqivfqdpggsmnprmsvrsivgeplq 124
Cdd:cd03222   22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPVYKP---------------------------------- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 125 vnrlaegaeltQKVadvldsvglkrehmnrfphEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEI 204
Cdd:cd03222   68 -----------QYI-------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRL 117

                        170       180
                 ....*....|....*....|....*....
gi 663511184 205 QEKLGLTFVFITHALNVVNHISDRVAVMY 233
Cdd:cd03222  118 SEEGKKTALVVEHDLAVLDYLSDRIHVFE 146

PRK13543

heme ABC exporter ATP-binding protein CcmA;

41-190

1.77e-09

heme ABC exporter ATP-binding protein CcmA;

Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 57.17 E-value: 1.77e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTipdRELRRRMQIVFQDPGgsMNPRMSVRsivg 120
Cdd:PRK13543  30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATR---GDRSRFMAYLGHLPG--LKADLSTL---- 100

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 663511184 121 EPLQVNRLAEGAELTQKVADVLDSVGLKrEHMNRFPHEFSGGQKQRLALARaLSLDPEFI-LLDEPTSALD 190
Cdd:PRK13543 101 ENLHFLCGLHGRRAKQMPGSALAIVGLA-GYEDTLVRQLSAGQKKRLALAR-LWLSPAPLwLLDEPYANLD 169

PRK10636

putative ABC transporter ATP-binding protein; Provisional

38-229

2.87e-09

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 58.26 E-value: 2.87e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGE-------------DIRTIP-----DRELR---R 96
Cdd:PRK10636  17 LDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNwqlawvnqetpalPQPALEyvidgDREYRqleA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  97 RMQIVFQDPGGSmnprmSVRSIVGEPLQVNRLAegaeLTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLD 176
Cdd:PRK10636  97 QLHDANERNDGH-----AIATIHGKLDAIDAWT----IRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALICR 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 663511184 177 PEFILLDEPTSALDVSVqaqVLNLLEEIQEKLGlTFVFITHALNVVNHISDRV 229
Cdd:PRK10636 168 SDLLLLDEPTNHLDLDA---VIWLEKWLKSYQG-TLILISHDRDFLDPIVDKI 216

PRK11147

ABC transporter ATPase component; Reviewed

3-204

4.44e-09

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 57.65 E-value: 4.44e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   3 EESRDGKVLIEVKGMKkwFPIKGGMLsevkihvraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVlYD 82
Cdd:PRK11147 311 EASRSGKIVFEMENVN--YQIDGKQL---------VKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRI-HC 378

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  83 GEdirtipdrelrrRMQIVFQDP-GGSMNPRMSVrsivgeplqVNRLAEGaelTQKVadvldSVGLKREHMNRFPHEF-- 159
Cdd:PRK11147 379 GT------------KLEVAYFDQhRAELDPEKTV---------MDNLAEG---KQEV-----MVNGRPRHVLGYLQDFlf 429

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184 160 ------------SGGQKQRLALARaLSLDP-EFILLDEPTSALDVsvqaQVLNLLEEI 204
Cdd:PRK11147 430 hpkramtpvkalSGGERNRLLLAR-LFLKPsNLLILDEPTNDLDV----ETLELLEEL 482

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

21-244

5.32e-09

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 57.43 E-value: 5.32e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  21 FPIKGGMLSEVKIHVR--------AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDR 92
Cdd:PRK10982 239 FPDKENKPGEVILEVRnltslrqpSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNAN 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  93 EL----------RRRMQIVFQDPGGSMNprmSVRSIVGEPLQVNRLAEGAELTQKVADVLDSVGLKREHMNRFPHEFSGG 162
Cdd:PRK10982 319 EAinhgfalvteERRSTGIYAYLDIGFN---SLISNIRNYKNKVGLLDNSRMKSDTQWVIDSMRVKTPGHRTQIGSLSGG 395

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 163 QKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIAN 242
Cdd:PRK10982 396 NQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLGITDRILVMSNGLVAGIVD 474


                 ..
gi 663511184 243 TA 244
Cdd:PRK10982 475 TK 476

PLN03073

ABC transporter F family; Provisional

137-249

5.98e-09

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 57.56 E-value: 5.98e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 137 KVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVqaqVLnLLEEIQEKLGLTFVFIT 216
Cdd:PLN03073 323 RAASILAGLSFTPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHA---VL-WLETYLLKWPKTFIVVS 398

                         90       100       110
                 ....*....|....*....|....*....|...
gi 663511184 217 HALNVVNHISDRVAVMYLGKIVEIANTADLFDK 249
Cdd:PLN03073 399 HAREFLNTVVTDILHLHGQKLVTYKGDYDTFER 431

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

35-246

8.31e-09

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 56.66 E-value: 8.31e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  35 VRAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTIPDRE-LRRRMQIVFQDpggsMNprM 113
Cdd:PRK10982  11 VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEaLENGISMVHQE----LN--L 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRSIVGEPLQVNRLAEGAEL---------TQKVADVLDSVGLKREHMNrfphEFSGGQKQRLALARALSLDPEFILLDE 184
Cdd:PRK10982  85 VLQRSVMDNMWLGRYPTKGMFvdqdkmyrdTKAIFDELDIDIDPRAKVA----TLSVSQMQMIEIAKAFSYNAKIVIMDE 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663511184 185 PTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADL 246
Cdd:PRK10982 161 PTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLAGL 221

ABCC_CFTR2

cd03289

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...

38-198

9.48e-09

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 55.63 E-value: 9.48e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPiTDGSVLYDGEDIRTIPDRELRRRMQIVFQDPggsmnprmsvrS 117
Cdd:cd03289   20 LENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVPLQKWRKAFGVIPQKV-----------F 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 118 IVGEPLQVNRLAEGAELTQKVADVLDSVGLKREhMNRFPHEF-----------SGGQKQRLALARALSLDPEFILLDEPT 186
Cdd:cd03289   88 IFSGTFRKNLDPYGKWSDEEIWKVAEEVGLKSV-IEQFPGQLdfvlvdggcvlSHGHKQLMCLARSVLSKAKILLLDEPS 166

                        170
                 ....*....|..
gi 663511184 187 SALDvSVQAQVL 198
Cdd:cd03289  167 AHLD-PITYQVI 177

ABC_UvrA

cd03238

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...

28-221

1.18e-08

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 53.87 E-value: 1.18e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  28 LSEVKIHVRAVDGVDLQIKRGETLGIVGESGCGKTTLgrvllglipITDGsvLYDGEDIRTIPDRELRRRMQIVFQDpgg 107
Cdd:cd03238    1 LTVSGANVHNLQNLDVSIPLNVLVVVTGVSGSGKSTL---------VNEG--LYASGKARLISFLPKFSRNKLIFID--- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 108 smnprmsvrsivgeplQVNRLAEgaeltqkvadvldsVGLKREHMNRFPHEFSGGQKQRLALARALSLDPE--FILLDEP 185
Cdd:cd03238   67 ----------------QLQFLID--------------VGLGYLTLGQKLSTLSGGELQRVKLASELFSEPPgtLFILDEP 116

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 663511184 186 TSALDVSVQAQVLNLLEEIQEkLGLTFVFITHALNV 221
Cdd:cd03238  117 STGLHQQDINQLLEVIKGLID-LGNTVILIEHNLDV 151

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

6-217

2.17e-08

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 55.71 E-value: 2.17e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    6 RDGKVLIEVKGMKKWFPIKggMLsevkihvraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYdGED 85
Cdd:TIGR03719 317 RLGDKVIEAENLTKAFGDK--LL---------IDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GET 384

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   86 IrtipdrelrrrmQIVFQDPG-GSMNPRMSVRSIVGEPL--------QVNRLAEGAELTQKVADVLDSVGlkrehmnrfp 156
Cdd:TIGR03719 385 V------------KLAYVDQSrDALDPNKTVWEEISGGLdiiklgkrEIPSRAYVGRFNFKGSDQQKKVG---------- 442

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 663511184  157 hEFSGGQKQRLALARALSLDPEFILLDEPTSALDVsvqaQVLNLLEEIQEKLGLTFVFITH 217
Cdd:TIGR03719 443 -QLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDV----ETLRALEEALLNFAGCAVVISH 498

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

5-252

2.96e-08

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 54.74 E-value: 2.96e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   5 SRDGKVLIEVKGMKKWFPikggmlsevkiHVRAVDGVDLQIKRGETLGIVGESGCGKTTlgrvllGLIPitdgsVLYDGE 84
Cdd:NF000106   7 SNGARNAVEVRGLVKHFG-----------EVKAVDGVDLDVREGTVLGVLGP*GAA**R------GALP-----AHV*GP 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  85 DIRTIP---------DRELRRRM---QIVFQDPGGSMNPRMSVRsIVGEPLQVNRlaegAELTQKVADVLDSVGLKrEHM 152
Cdd:NF000106  65 DAGRRPwrf*twcanRRALRRTIg*hRPVR*GRRESFSGRENLY-MIGR*LDLSR----KDARARADELLERFSLT-EAA 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 153 NRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVM 232
Cdd:NF000106 139 GRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVI 217

                        250       260
                 ....*....|....*....|....*....
gi 663511184 233 YLGKIVEIANTADLFDK---------PAH 252
Cdd:NF000106 218 DRGRVIADGKVDELKTKvggrtlqirPAH 246

PRK15064

ABC transporter ATP-binding protein; Provisional

12-245

3.41e-08

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 54.90 E-value: 3.41e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  12 IEVKGMKKWFPikGGMLsevkihvraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLY-DGEDIRTIP 90
Cdd:PRK15064 320 LEVENLTKGFD--NGPL---------FKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWsENANIGYYA 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  91 ---------DRELRRRMQiVFQDPGGSmnpRMSVRSIVGeplqvnRLAEGAELTQKVADVLdsvglkrehmnrfphefSG 161
Cdd:PRK15064 389 qdhaydfenDLTLFDWMS-QWRQEGDD---EQAVRGTLG------RLLFSQDDIKKSVKVL-----------------SG 441

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 162 GQKQRLALARALSLDPEFILLDEPTSALDV-SVQAqvLNL-LEEIQeklGlTFVFITHALNVVNHISDRVAVMYLGKIVE 239
Cdd:PRK15064 442 GEKGRMLFGKLMMQKPNVLVMDEPTNHMDMeSIES--LNMaLEKYE---G-TLIFVSHDREFVSSLATRIIEITPDGVVD 515


                 ....*.
gi 663511184 240 IANTAD 245
Cdd:PRK15064 516 FSGTYE 521

PRK10636

putative ABC transporter ATP-binding protein; Provisional

38-237

6.95e-08

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 54.02 E-value: 6.95e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  38 VDGVDLQIKRGETLGIVGESGCGKTTLGRVLLG-LIPITDGSVLYDGEDIRTIPDRELRrrmqivFQDPGGSmnprmsvr 116
Cdd:PRK10636 328 LDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGeLAPVSGEIGLAKGIKLGYFAQHQLE------FLRADES-------- 393

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 sivgePLQ-VNRLAEgAELTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQA 195
Cdd:PRK10636 394 -----PLQhLARLAP-QELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQ 467

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 663511184 196 QVLNLLEEIQEKLgltfVFITHALNVVNHISDRVAVMYLGKI 237
Cdd:PRK10636 468 ALTEALIDFEGAL----VVVSHDRHLLRSTTDDLYLVHDGKV 505

GguA

NF040905

sugar ABC transporter ATP-binding protein;

4-238

8.38e-08

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 53.64 E-value: 8.38e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   4 ESRDGKVLIEVKGMKKWFPIKggmlSEVKIhvraVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGL---IPITdGSVL 80
Cdd:NF040905 250 TPKIGEVVFEVKNWTVYHPLH----PERKV----VDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRsygRNIS-GTVF 320

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  81 YDGE--DIRTIPD---------RELRRRMQIVFQDP-----GGSMNPRMSVRSIVGEPLQVnRLAEG--AELTQKVADVL 142
Cdd:NF040905 321 KDGKevDVSTVSDaidaglayvTEDRKGYGLNLIDDikrniTLANLGKVSRRGVIDENEEI-KVAEEyrKKMNIKTPSVF 399

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 143 DSVGlkrehmnrfphEFSGGQKQRLALARALSLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVV 222
Cdd:NF040905 400 QKVG-----------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPEL 467

                        250
                 ....*....|....*.
gi 663511184 223 NHISDRVAVMYLGKIV 238
Cdd:NF040905 468 LGMCDRIYVMNEGRIT 483

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

48-217

9.55e-08

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 53.40 E-value: 9.55e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   48 GETLGIVGESGCGKTTLGRVLLGLipitDGSvlYDGEdIRTIPDRelrrRMQIVFQDPggSMNPRMSVRSIVGEPLQ--V 125
Cdd:TIGR03719  31 GAKIGVLGLNGAGKSTLLRIMAGV----DKD--FNGE-ARPQPGI----KVGYLPQEP--QLDPTKTVRENVEEGVAeiK 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  126 NRLAEGAELTQKVAD-----------------VLDSVG---LKRE---HMN--RFP------HEFSGGQKQRLALARALS 174
Cdd:TIGR03719  98 DALDRFNEISAKYAEpdadfdklaaeqaelqeIIDAADawdLDSQleiAMDalRCPpwdadvTKLSGGERRRVALCRLLL 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 663511184  175 LDPEFILLDEPTSALDvsvqAQVLNLLEE-IQEKLGlTFVFITH 217
Cdd:TIGR03719 178 SKPDMLLLDEPTNHLD----AESVAWLERhLQEYPG-TVVAVTH 216

ABCC_CFTR1

cd03291

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...

41-197

1.01e-07

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 52.55 E-value: 1.01e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEdIRTIPdrelrrrmQIVFQDPG--------GSMNPR 112
Cdd:cd03291   56 INLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR-ISFSS--------QFSWIMPGtikeniifGVSYDE 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 113 MSVRSIVgeplQVNRLAEG-AELTQKVADVLDSVGLKrehmnrfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:cd03291  127 YRYKSVV----KACQLEEDiTKFPEKDNTVLGEGGIT----------LSGGQRARISLARAVYKDADLYLLDSPFGYLDV 192


                 ....*.
gi 663511184 192 SVQAQV 197
Cdd:cd03291  193 FTEKEI 198

PRK13540

cytochrome c biogenesis protein CcmA; Provisional

41-206

1.04e-07

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 51.49 E-value: 1.04e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  41 VDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEDIRTipDRELRRRmQIVFQDPGGSMNPRMSVRSIVG 120
Cdd:PRK13540  20 ISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKK--DLCTYQK-QLCFVGHRSGINPYLTLRENCL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 121 EPLQVNRLAEGAELTQKVadvldsvgLKREHMNRFP-HEFSGGQKQRLALARALSLDPEFILLDEPTSALDvsvQAQVLN 199
Cdd:PRK13540  97 YDIHFSPGAVGITELCRL--------FSLEHLIDYPcGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALD---ELSLLT 165


                 ....*..
gi 663511184 200 LLEEIQE 206
Cdd:PRK13540 166 IITKIQE 172

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

42-232

1.22e-07

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 53.09 E-value: 1.22e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  42 DLQIKRGETLGIVGESGCGKTTLGRVLLGLIPitdgsvLYDGE---DIRTIPDRELRRRMQIV---FQD-------PGGS 108
Cdd:PRK10938  23 SLTLNAGDSWAFVGANGSGKSALARALAGELP------LLSGErqsQFSHITRLSFEQLQKLVsdeWQRnntdmlsPGED 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 109 MNPRMSVRSIVGEPLQVNRLAEGAELTQkVADVLDsvglkrehmNRFPHeFSGGQKQRLALARALSLDPEFILLDEPTSA 188
Cdd:PRK10938  97 DTGRTTAEIIQDEVKDPARCEQLAQQFG-ITALLD---------RRFKY-LSTGETRKTLLCQALMSEPDLLILDEPFDG 165

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 663511184 189 LDVSVQAQVLNLLEEIQEKlGLTFVFIthaLNVVNHISD---RVAVM 232
Cdd:PRK10938 166 LDVASRQQLAELLASLHQS-GITLVLV---LNRFDEIPDfvqFAGVL 208

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

25-198

1.86e-07

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 52.99 E-value: 1.86e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    25 GGMLSEVKIHVRAV-DGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEdIRTIPdrelrrrmQIVFQ 103
Cdd:TIGR01271  428 GLFFSNFSLYVTPVlKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR-ISFSP--------QTSWI 498

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   104 DPG--------GSMNPRMSVRSIVgeplQVNRLAEG-AELTQKVADVLDSVGLKrehmnrfpheFSGGQKQRLALARALS 174
Cdd:TIGR01271  499 MPGtikdniifGLSYDEYRYTSVI----KACQLEEDiALFPEKDKTVLGEGGIT----------LSGGQRARISLARAVY 564

                          170       180
                   ....*....|....*....|....
gi 663511184   175 LDPEFILLDEPTSALDVSVQAQVL 198
Cdd:TIGR01271  565 KDADLYLLDSPFTHLDVVTEKEIF 588

ABC_Rad50

cd03240

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...

53-227

2.10e-07

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.

Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 50.68 E-value: 2.10e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  53 IVGESGCGKTT----LGRVLLGLIPITDGSVLYDGEDIRtipdrELRRRMQIvfqdpggsmnpRMSVRSIVGEPLQVNRl 128
Cdd:cd03240   27 IVGQNGAGKTTiieaLKYALTGELPPNSKGGAHDPKLIR-----EGEVRAQV-----------KLAFENANGKKYTITR- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 129 aegaeltqKVADVLDSVGLKREHMN----RFPHEFSGGQKQ------RLALARALSLDPEFILLDEPTSALDV-SVQAQV 197
Cdd:cd03240   90 --------SLAILENVIFCHQGESNwpllDMRGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEeNIEESL 161

                        170       180       190
                 ....*....|....*....|....*....|
gi 663511184 198 LNLLEEIQEKLGLTFVFITHALNVVNHISD 227
Cdd:cd03240  162 AEIIEERKSQKNFQLIVITHDEELVDAADH 191

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

30-201

4.55e-07

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 51.65 E-value: 4.55e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    30 EVKI---HVRAVDGVDLQIKRGETLGIVGESGCGKTTL-----GRVLLGLipITDGSVLYDGEDIrtipDRELRRRMQIV 101
Cdd:TIGR00956  768 EVKIkkeKRVILNNVDGWVKPGTLTALMGASGAGKTTLlnvlaERVTTGV--ITGGDRLVNGRPL----DSSFQRSIGYV 841

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   102 FQdpggsmNPRMSVRSIVGEPLQVN-RLAEGAELT--------QKVADVLDS-------VGLKREHMNRfphefsgGQKQ 165
Cdd:TIGR00956  842 QQ------QDLHLPTSTVRESLRFSaYLRQPKSVSksekmeyvEEVIKLLEMesyadavVGVPGEGLNV-------EQRK 908

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 663511184   166 RLALARALSLDPEFIL-LDEPTSALDVSVQAQVLNLL 201
Cdd:TIGR00956  909 RLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLM 945

PRK13546

teichoic acids export ABC transporter ATP-binding subunit TagH;

37-249

1.02e-06

teichoic acids export ABC transporter ATP-binding subunit TagH;

Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 49.43 E-value: 1.02e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  37 AVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYDGEdIRTIpdrelrrrmqivfqdpggSMNPRMSVR 116
Cdd:PRK13546  39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE-VSVI------------------AISAGLSGQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 117 SIVGEPLQVNRLAEGaeLTQKVADVLDSVGLKREHMNRFPHE----FSGGQKQRLALARALSLDPEFILLDEPTSALDVS 192
Cdd:PRK13546 100 LTGIENIEFKMLCMG--FKRKEIKAMTPKIIEFSELGEFIYQpvkkYSSGMRAKLGFSINITVNPDILVIDEALSVGDQT 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 663511184 193 VQAQVLNLLEEIQEKlGLTFVFITHALNVVNHISDRVAVMYLGKIVEIANTADLFDK 249
Cdd:PRK13546 178 FAQKCLDKIYEFKEQ-NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPK 233

ABCG_PDR_domain2

cd03232

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...

39-204

3.23e-06

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 47.24 E-value: 3.23e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  39 DGVDLQIKRGETLGIVGESGCGKTTLGRVL-----LGLIpitDGSVLYDGEDIrtipDRELRRRMQIVFQDPggSMNPRM 113
Cdd:cd03232   24 NNISGYVKPGTLTALMGESGAGKTTLLDVLagrktAGVI---TGEILINGRPL----DKNFQRSTGYVEQQD--VHSPNL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 114 SVRsivgEPLQVNRLAEGaeltqkvadvldsvglkrehmnrfpheFSGGQKQRLALARALSLDPEFILLDEPTSALDVSV 193
Cdd:cd03232   95 TVR----EALRFSALLRG---------------------------LSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQA 143

                        170
                 ....*....|.
gi 663511184 194 QAQVLNLLEEI 204
Cdd:cd03232  144 AYNIVRFLKKL 154

PRK15064

ABC transporter ATP-binding protein; Provisional

52-227

4.37e-06

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 48.35 E-value: 4.37e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  52 GIVGESGCGKTTLGRVLLG-LIPiTDGSVLYDG--------------EDIRTIP-----DRELRRRMQ----IVfqdpgg 107
Cdd:PRK15064  31 GLIGANGCGKSTFMKILGGdLEP-SAGNVSLDPnerlgklrqdqfafEEFTVLDtvimgHTELWEVKQerdrIY------ 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 108 sMNPRMS----VRsiVGEpLQVnRLAE----GAEltQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEF 179
Cdd:PRK15064 104 -ALPEMSeedgMK--VAD-LEV-KFAEmdgyTAE--ARAGELLLGVGIPEEQHYGLMSEVAPGWKLRVLLAQALFSNPDI 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 663511184 180 ILLDEPTSALDVSvqaqVLNLLEEIQEKLGLTFVFITHA---LN-VVNHISD 227
Cdd:PRK15064 177 LLLDEPTNNLDIN----TIRWLEDVLNERNSTMIIISHDrhfLNsVCTHMAD 224

ABC_Class2

cd03227

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...

160-233

5.99e-06

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.

Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 45.81 E-value: 5.99e-06

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 160 SGGQKQRLALARALSL-----DPeFILLDEPTSALDVSVQAQVLNLLEEiQEKLGLTFVFITHALNVVNhISDRVAVMY 233
Cdd:cd03227   79 SGGEKELSALALILALaslkpRP-LYILDEIDRGLDPRDGQALAEAILE-HLVKGAQVIVITHLPELAE-LADKLIHIK 154

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

6-191

9.15e-06

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 47.42 E-value: 9.15e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   6 RDGKVLIEVKGMKKWFpikGGMLsevkihvrAVDGVDLQIKRGETLGIVGESGCGKTTLGRVLLGLIPITDGSVLYdGED 85
Cdd:PRK11819 319 RLGDKVIEAENLSKSF---GDRL--------LIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GET 386

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  86 IrtipdrelrrrmQIVFQDPG-GSMNPRMSVRSIVGEPL--------QVNRLA-------EGAElTQKVADVLdsvglkr 149
Cdd:PRK11819 387 V------------KLAYVDQSrDALDPNKTVWEEISGGLdiikvgnrEIPSRAyvgrfnfKGGD-QQKKVGVL------- 446

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 663511184 150 ehmnrfphefSGGQKQRLALARALSLDPEFILLDEPTSALDV 191
Cdd:PRK11819 447 ----------SGGERNRLHLAKTLKQGGNVLLLDEPTNDLDV 478

PLN03073

ABC transporter F family; Provisional

40-201

8.54e-05

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 44.47 E-value: 8.54e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  40 GVDLQIKrgetLGIVGESGCGKTTLGRVLLGLIPITDGSVLydgedirtipdRELRRRMQIVFQDPGGSMNprMSVRSIv 119
Cdd:PLN03073 531 GIDLDSR----IAMVGPNGIGKSTILKLISGELQPSSGTVF-----------RSAKVRMAVFSQHHVDGLD--LSSNPL- 592

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 120 gepLQVNRLAEGAeLTQKVADVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSLDPEFILLDEPTSALDV-SVQAQVL 198
Cdd:PLN03073 593 ---LYMMRCFPGV-PEQKLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLdAVEALIQ 668


                 ...
gi 663511184 199 NLL 201
Cdd:PLN03073 669 GLV 671

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

35-238

9.08e-05

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 44.33 E-value: 9.08e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184    35 VRAVDGVdlqIKRGETLGIVGESGCGKTTLGRVLLGLIP----ITDGSVLYDGedirtIPDRELRR--RMQIVFQDPGGS 108
Cdd:TIGR00956   77 LKPMDGL---IKPGELTVVLGRPGSGCSTLLKTIASNTDgfhiGVEGVITYDG-----ITPEEIKKhyRGDVVYNAETDV 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   109 MNPRMSV----------RSIVGEPLQVNRLaegaELTQKVADV-LDSVGLKREHMNRFPHEF----SGGQKQRLALARAL 173
Cdd:TIGR00956  149 HFPHLTVgetldfaarcKTPQNRPDGVSRE----EYAKHIADVyMATYGLSHTRNTKVGNDFvrgvSGGERKRVSIAEAS 224

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184   174 SLDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKLGLT-FVFITHALNVVNHISDRVAVMYLGKIV 238
Cdd:TIGR00956  225 LGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTTpLVAIYQCSQDAYELFDKVIVLYEGYQI 290

ABC_UvrA_II

cd03271

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...

140-222

1.19e-04

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 42.99 E-value: 1.19e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 140 DVLDSVGLKREHMNRFPHEFSGGQKQRLALARALSL---DPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFIT 216
Cdd:cd03271  151 QTLCDVGLGYIKLGQPATTLSGGEAQRIKLAKELSKrstGKTLYILDEPTTGLHFHDVKKLLEVLQRLVDK-GNTVVVIE 229


                 ....*.
gi 663511184 217 HALNVV 222
Cdd:cd03271  230 HNLDVI 235

uvra

TIGR00630

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...

160-222

1.89e-04

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 43.46 E-value: 1.89e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511184  160 SGGQKQRLALARALS---LDPEFILLDEPTSALDVSVQAQVLNLLEEIQEKlGLTFVFITHALNVV 222
Cdd:TIGR00630 831 SGGEAQRIKLAKELSkrsTGRTLYILDEPTTGLHFDDIKKLLEVLQRLVDK-GNTVVVIEHNLDVI 895

SbcC

COG0419

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];

53-217

2.17e-04

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];

Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 41.92 E-value: 2.17e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  53 IVGESGCGKTTL---------GRVLlGLIPITDGSVLYDGEDIR-----TIPDRELR-RRMQ---IVFQDPGGSmnprmS 114
Cdd:COG0419   28 IVGPNGAGKSTIleairyalyGKAR-SRSKLRSDLINVGSEEASvelefEHGGKRYRiERRQgefAEFLEAKPS-----E 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184 115 VRSIVGEPLQVNRLAEG--------AELTQKVADVLDSVGLKREHMNRF-----PHEFSGGQKQRLALARALSLdpefiL 181
Cdd:COG0419  102 RKEALKRLLGLEIYEELkerlkeleEALESALEELAELQKLKQEILAQLsgldpIETLSGGERLRLALADLLSL-----I 176

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 663511184 182 LDepTSALDVSVQAQVLNLLEEIQeklgltfvFITH 217
Cdd:COG0419  177 LD--FGSLDEERLERLLDALEELA--------IITH 202

PRK00635

excinuclease ABC subunit A; Provisional

142-229

2.51e-04

excinuclease ABC subunit A; Provisional

Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 43.28 E-value: 2.51e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  142 LDSVGLKREHMNRFPHEFSGGQKQRLALARAL---SLDPEFILLDEPTSAL---DVSVQAQVLNLLEEiqekLGLTFVFI 215
Cdd:PRK00635  793 LCSLGLDYLPLGRPLSSLSGGEIQRLKLAYELlapSKKPTLYVLDEPTTGLhthDIKALIYVLQSLTH----QGHTVVII 868

                          90
                  ....*....|....
gi 663511184  216 THALNVVNhISDRV 229
Cdd:PRK00635  869 EHNMHVVK-VADYV 881

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

160-217

3.90e-04

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 42.03 E-value: 3.90e-04

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 663511184 160 SGGQKQRLALARALSLDPEFILLDEPTSALDvsvqAQVLNLLEE-IQEKLGlTFVFITH 217
Cdd:PRK11819 165 SGGERRRVALCRLLLEKPDMLLLDEPTNHLD----AESVAWLEQfLHDYPG-TVVAVTH 218

SbcC_Walker_B

pfam13558

SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ...

139-203

4.18e-04

SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.

Pssm-ID: 463921 [Multi-domain] Cd Length: 90 Bit Score: 38.76 E-value: 4.18e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 663511184  139 ADVLDSVGLKREHMNRFpHEFSGGQKQRLA-LARALSL------------DPEFILLDEPTSALDVSVQAQVLNLLEE 203
Cdd:pfam13558  14 VEVRDEDGSEVETYRRS-GGLSGGEKQLLAyLPLAAALaaqygsaegrppAPRLVFLDEAFAKLDEENIRTALELLRA 90

rad50

TIGR00606

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

160-236

1.29e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 40.80 E-value: 1.29e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184   160 SGGQKQ------RLALARALSLDPEFILLDEPTSALDVS-VQAQVLNLLEEIQEK---LGLTFVFITHALNVVNHI--SD 227
Cdd:TIGR00606 1201 SAGQKVlasliiRLALAETFCLNCGIIALDEPTTNLDREnIESLAHALVEIIKSRsqqRNFQLLVITHDEDFVELLgrSE 1280

                           90
                   ....*....|
gi 663511184   228 RVAVMY-LGK 236
Cdd:TIGR00606 1281 YVEKFYrLKK 1290

RepA_RSF1010_like

cd01125

Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family ...

48-126

3.37e-03

Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family includes the homo-hexameric replicative helicase RepA encoded by plasmid RSF1010. RSF1010 is found in most Gram-negative bacteria and some Gram-positive bacteria . The RepA protein of Plasmid RSF1010 is a 5'-3' DNA helicase which can utilize ATP, dATP, GTP and dGTP (and CTP and dCTP to a lesser extent).

Pssm-ID: 410870 Cd Length: 238 Bit Score: 38.52 E-value: 3.37e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511184  48 GETLGIVGESGCGKTTL----------GRVLLGLIPITDGSVLY-DGEDirtiPDRELRRRMQIVFQDPGGSMNPRmsVR 116
Cdd:cd01125    1 GTLGMLVGPPGSGKSFLaldlavavatGRDWLGERRVKQGRVVYlAAED----PRDGLRRRLKAIGAHLGDEDAAL--AE 74

                         90
                 ....*....|
gi 663511184 117 SIVGEPLQVN 126
Cdd:cd01125   75 NLVIENLRGK 84

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01