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Conserved domains on  [gi|663511206|gb|AIF01809|]
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hypothetical protein containing chitin-binding domain type 3 [uncultured marine group II/III euryarchaeote KM3_14_H03]

Protein Classification

PKD domain-containing protein( domain architecture ID 16071123)

PKD domain-containing protein containing one or more repeats of the polycystic kidney disease (PKD) motif

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PKD_4 pfam18911
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
 407-494 1.60e-10

PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.


:

Pssm-ID: 436824 [Multi-domain]  Cd Length: 85  Bit Score: 57.28  E-value: 1.60e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  407 NLPPVADAGDDITVEADDdgkaEVLLDGSRSFDPDGDIASWAWEddrervigHSDRIRVKLAEGVHVF--------HLTV 478
Cdd:pfam18911   1 NAAPVADAGGDRIVAEGE----TVTFDASASDDPDGDILSYRWD--------FGDGTTATGANVSHTYaapgtytvTLTV 68

                          90
                  ....*....|....*..
gi 663511206  479 TDDRGSATKS-SITVRV 494
Cdd:pfam18911  69 TDDSGASNSTaTDTVTV 85
 
Name Accession Description Interval E-value
PKD_4 pfam18911
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
 407-494 1.60e-10

PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.


Pssm-ID: 436824 [Multi-domain]  Cd Length: 85  Bit Score: 57.28  E-value: 1.60e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  407 NLPPVADAGDDITVEADDdgkaEVLLDGSRSFDPDGDIASWAWEddrervigHSDRIRVKLAEGVHVF--------HLTV 478
Cdd:pfam18911   1 NAAPVADAGGDRIVAEGE----TVTFDASASDDPDGDILSYRWD--------FGDGTTATGANVSHTYaapgtytvTLTV 68

                          90
                  ....*....|....*..
gi 663511206  479 TDDRGSATKS-SITVRV 494
Cdd:pfam18911  69 TDDSGASNSTaTDTVTV 85
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 407-495 1.22e-08

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 57.74  E-value: 1.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  407 NLPPVADAGDDITVeaddDGKAEVLLDGSRSFDPDGDIASWAWeddrERVIGHSdrirVKL----------------AEG 470
Cdd:NF038112 1185 NRRPVANAGPDQTV----LERTTVTLNGSGSFDPDGDPLTYAW----TQVSGPA----VTLtgadtatpsftapevtADT 1252

                          90       100
                  ....*....|....*....|....*
gi 663511206  471 VHVFHLTVTDDRGSATKSSITVRVR 495
Cdd:NF038112 1253 VLTFQLVVSDGTKTSAPDTVTVLVR 1277
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 404-495 7.59e-07

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 51.97  E-value: 7.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  404 RAINLPPVADAGDDITVEAdddgKAEVLLDGSRSfDPDGDIASWAWEDDRERVIGHSDRIRVK--------LAEGVHVFH 475
Cdd:NF038112 1370 RNVNRAPVANAGADQTVDE----RSTVTLSGSAT-DPDGDALTYAWTQTAGPTVTLTGADTATasftapevAADTELTFQ 1444

                          90       100
                  ....*....|....*....|
gi 663511206  476 LTVTDDRGSATKSSITVRVR 495
Cdd:NF038112 1445 LTVSADGQASADVTVTVTVR 1464
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 402-495 9.50e-05

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 45.42  E-value: 9.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  402 SARAINLPPVADAGDDITVEAdddgKAEVLLDGSRSfDPDGDIASWAWeddrERVIGHSdrirVKL-------------- 467
Cdd:NF038112 1462 TVRNVNRAPVAHAGESITVDE----GSTVTLDASAT-DPDGDTLTYAW----TQVAGPS----VTLtgadsakltftape 1528

                          90       100       110
                  ....*....|....*....|....*....|
gi 663511206  468 --AEGVHVFHLTVTDDRGSATKSSITVRVR 495
Cdd:NF038112 1529 vsADTTLTFSLTVTDGSGSSGPVVVTVTVK 1558
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 404-493 2.46e-04

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 43.88  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  404 RAINLPPVADAGDDITVeaddDGKAEVLLDGSRSfDPDGDIASWAWEDDRERVIGHSDRIRVK--------LAEGVHVFH 475
Cdd:NF038112 1277 RNVNRAPVAVAGAPATV----DERSTVTLDGSGT-DADGDALTYAWTQTSGPAVTLTGATTATatftapevTADTQLTFT 1351

                          90
                  ....*....|....*....
gi 663511206  476 LTVTDDRGSATKS-SITVR 493
Cdd:NF038112 1352 LTVSDGTASATDTvTVTVR 1370
PKD cd00146
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ...
 424-494 3.56e-03

polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.


Pssm-ID: 238084 [Multi-domain]  Cd Length: 81  Bit Score: 36.32  E-value: 3.56e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511206 424 DDGKAEVLLDGSRSFDPDGDIASWAWEDD-----RERVIGHSdrirvKLAEGVHVFHLTVTDDRGSATKSSITVRV 494
Cdd:cd00146   11 AELGASVTFSASDSSGGSIVSYKWDFGDGevsssGEPTVTHT-----YTKPGTYTVTLTVTNAVGSSSTKTTTVVV 81
PKD smart00089
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ...
 429-494 4.31e-03

Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.


Pssm-ID: 214510 [Multi-domain]  Cd Length: 79  Bit Score: 36.28  E-value: 4.31e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 663511206   429 EVLLDGSRSfdPDGDIASWAW-----EDDRERVIGHSdrirvKLAEGVHVFHLTVTDDRGSATKsSITVRV 494
Cdd:smart00089  16 SVTFTATSS--DDGSIVSYTWdfgdgTSSTGPTVTHT-----YTKPGTYTVTLTVTNAVGSASA-TVTVVV 78
 
Name Accession Description Interval E-value
PKD_4 pfam18911
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
 407-494 1.60e-10

PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.


Pssm-ID: 436824 [Multi-domain]  Cd Length: 85  Bit Score: 57.28  E-value: 1.60e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  407 NLPPVADAGDDITVEADDdgkaEVLLDGSRSFDPDGDIASWAWEddrervigHSDRIRVKLAEGVHVF--------HLTV 478
Cdd:pfam18911   1 NAAPVADAGGDRIVAEGE----TVTFDASASDDPDGDILSYRWD--------FGDGTTATGANVSHTYaapgtytvTLTV 68

                          90
                  ....*....|....*..
gi 663511206  479 TDDRGSATKS-SITVRV 494
Cdd:pfam18911  69 TDDSGASNSTaTDTVTV 85
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 407-495 1.22e-08

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 57.74  E-value: 1.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  407 NLPPVADAGDDITVeaddDGKAEVLLDGSRSFDPDGDIASWAWeddrERVIGHSdrirVKL----------------AEG 470
Cdd:NF038112 1185 NRRPVANAGPDQTV----LERTTVTLNGSGSFDPDGDPLTYAW----TQVSGPA----VTLtgadtatpsftapevtADT 1252

                          90       100
                  ....*....|....*....|....*
gi 663511206  471 VHVFHLTVTDDRGSATKSSITVRVR 495
Cdd:NF038112 1253 VLTFQLVVSDGTKTSAPDTVTVLVR 1277
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 404-495 7.59e-07

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 51.97  E-value: 7.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  404 RAINLPPVADAGDDITVEAdddgKAEVLLDGSRSfDPDGDIASWAWEDDRERVIGHSDRIRVK--------LAEGVHVFH 475
Cdd:NF038112 1370 RNVNRAPVANAGADQTVDE----RSTVTLSGSAT-DPDGDALTYAWTQTAGPTVTLTGADTATasftapevAADTELTFQ 1444

                          90       100
                  ....*....|....*....|
gi 663511206  476 LTVTDDRGSATKSSITVRVR 495
Cdd:NF038112 1445 LTVSADGQASADVTVTVTVR 1464
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 402-495 9.50e-05

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 45.42  E-value: 9.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  402 SARAINLPPVADAGDDITVEAdddgKAEVLLDGSRSfDPDGDIASWAWeddrERVIGHSdrirVKL-------------- 467
Cdd:NF038112 1462 TVRNVNRAPVAHAGESITVDE----GSTVTLDASAT-DPDGDTLTYAW----TQVAGPS----VTLtgadsakltftape 1528

                          90       100       110
                  ....*....|....*....|....*....|
gi 663511206  468 --AEGVHVFHLTVTDDRGSATKSSITVRVR 495
Cdd:NF038112 1529 vsADTTLTFSLTVTDGSGSSGPVVVTVTVK 1558
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 404-493 2.46e-04

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 43.88  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663511206  404 RAINLPPVADAGDDITVeaddDGKAEVLLDGSRSfDPDGDIASWAWEDDRERVIGHSDRIRVK--------LAEGVHVFH 475
Cdd:NF038112 1277 RNVNRAPVAVAGAPATV----DERSTVTLDGSGT-DADGDALTYAWTQTSGPAVTLTGATTATatftapevTADTQLTFT 1351

                          90
                  ....*....|....*....
gi 663511206  476 LTVTDDRGSATKS-SITVR 493
Cdd:NF038112 1352 LTVSDGTASATDTvTVTVR 1370
PKD cd00146
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ...
 424-494 3.56e-03

polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.


Pssm-ID: 238084 [Multi-domain]  Cd Length: 81  Bit Score: 36.32  E-value: 3.56e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663511206 424 DDGKAEVLLDGSRSFDPDGDIASWAWEDD-----RERVIGHSdrirvKLAEGVHVFHLTVTDDRGSATKSSITVRV 494
Cdd:cd00146   11 AELGASVTFSASDSSGGSIVSYKWDFGDGevsssGEPTVTHT-----YTKPGTYTVTLTVTNAVGSSSTKTTTVVV 81
PKD smart00089
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ...
 429-494 4.31e-03

Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.


Pssm-ID: 214510 [Multi-domain]  Cd Length: 79  Bit Score: 36.28  E-value: 4.31e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 663511206   429 EVLLDGSRSfdPDGDIASWAW-----EDDRERVIGHSdrirvKLAEGVHVFHLTVTDDRGSATKsSITVRV 494
Cdd:smart00089  16 SVTFTATSS--DDGSIVSYTWdfgdgTSSTGPTVTHT-----YTKPGTYTVTLTVTNAVGSASA-TVTVVV 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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