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Conserved domains on  [gi|717492109|gb|AIW81273|]
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von Willebrand factor, partial [Cheirogaleus crossleyi]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VWD super family cl47498
von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is ...
 5-85 1.43e-20

von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.


The actual alignment was detected with superfamily member pfam00094:

Pssm-ID: 459671 [Multi-domain]  Cd Length: 154  Bit Score: 79.34  E-value: 1.43e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 717492109    5 SSHFKSFDNRHFTFSGICQYLLARDC-EDHSFSIVIETVQCADDPDAVCTRSVTVRLPALHnslVKLKHGGGVAMDGQDI 83
Cdd:pfam00094   6 DPHYVTFDGVKYTFPGTCTYVLAKDCsEEPDFSFSVTNKNCNGGASGVCLKSVTVIVGDLE---ITLQKGGTVLVNGQKV 82


                  ..
gi 717492109   84 QL 85
Cdd:pfam00094  83 SL 84
 
Name Accession Description Interval E-value
VWD pfam00094
von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is ...
 5-85 1.43e-20

von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.


Pssm-ID: 459671 [Multi-domain]  Cd Length: 154  Bit Score: 79.34  E-value: 1.43e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 717492109    5 SSHFKSFDNRHFTFSGICQYLLARDC-EDHSFSIVIETVQCADDPDAVCTRSVTVRLPALHnslVKLKHGGGVAMDGQDI 83
Cdd:pfam00094   6 DPHYVTFDGVKYTFPGTCTYVLAKDCsEEPDFSFSVTNKNCNGGASGVCLKSVTVIVGDLE---ITLQKGGTVLVNGQKV 82


                  ..
gi 717492109   84 QL 85
Cdd:pfam00094  83 SL 84
VWD smart00216
von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D ...
 6-85 3.85e-15

von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D domains: D1 and D2 are present within the N-terminal propeptide whereas the remaining D domains are required for multimerisation.


Pssm-ID: 214566 [Multi-domain]  Cd Length: 163  Bit Score: 65.89  E-value: 3.85e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 717492109     6 SHFKSFDNRHFTFSGICQYLLARDCEDH-SFSIVIETVQCadDPDAVCTRSVTVRLPAlhNSLVKLKHGGGVAMDGQDIQ 84
Cdd:smart00216  18 PHYTTFDGVAYTFPGNCYYVLAQDCSSEpTFSVLLKNVPC--GGGATCLKSVKVELNG--DEIELKDDNGKVTVNGQQVS 93


                   .
gi 717492109    85 L 85
Cdd:smart00216  94 L 94
 
Name Accession Description Interval E-value
VWD pfam00094
von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is ...
 5-85 1.43e-20

von Willebrand factor type D domain; Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.


Pssm-ID: 459671 [Multi-domain]  Cd Length: 154  Bit Score: 79.34  E-value: 1.43e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 717492109    5 SSHFKSFDNRHFTFSGICQYLLARDC-EDHSFSIVIETVQCADDPDAVCTRSVTVRLPALHnslVKLKHGGGVAMDGQDI 83
Cdd:pfam00094   6 DPHYVTFDGVKYTFPGTCTYVLAKDCsEEPDFSFSVTNKNCNGGASGVCLKSVTVIVGDLE---ITLQKGGTVLVNGQKV 82


                  ..
gi 717492109   84 QL 85
Cdd:pfam00094  83 SL 84
VWD smart00216
von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D ...
 6-85 3.85e-15

von Willebrand factor (vWF) type D domain; Von Willebrand factor contains several type D domains: D1 and D2 are present within the N-terminal propeptide whereas the remaining D domains are required for multimerisation.


Pssm-ID: 214566 [Multi-domain]  Cd Length: 163  Bit Score: 65.89  E-value: 3.85e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 717492109     6 SHFKSFDNRHFTFSGICQYLLARDCEDH-SFSIVIETVQCadDPDAVCTRSVTVRLPAlhNSLVKLKHGGGVAMDGQDIQ 84
Cdd:smart00216  18 PHYTTFDGVAYTFPGNCYYVLAQDCSSEpTFSVLLKNVPC--GGGATCLKSVKVELNG--DEIELKDDNGKVTVNGQQVS 93


                   .
gi 717492109    85 L 85
Cdd:smart00216  94 L 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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