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Conserved domains on  [gi|749393523|gb|AJF17775|]
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p7e4, partial [Xenopus laevis]

Protein Classification

PHR domain-containing protein( domain architecture ID 10547107)

PHR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHR pfam08005
PHR domain; This domain is called PHR as it was original found in the proteins PAM, highwire ...
 69-173 3.72e-38

PHR domain; This domain is called PHR as it was original found in the proteins PAM, highwire and RPM. This domain can be duplicated in the highwire, PFAM and PRM sequence. The C-terminal region of the protein BTBD1 includes the PHR domain and is known to interact with Topoisomerase I, an enzyme which relaxes DNA supercoils.


:

Pssm-ID: 462339  Cd Length: 150  Bit Score: 127.74  E-value: 3.72e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749393523   69 HRFQSSAYRsnqWRYRGRC-DSIQFAVDKRIFIAGLGLYGSSCGKAEYSVKIELK------RQGVVLAQNLTKFVSDGCS 141
Cdd:pfam08005   1 NRFQSTGGG---WGYSGGSpDAIRFSVDRDIFLVGFGLYGSIGGPADYSVKIELIdgerweSLGEVLGENDTTFSSDGSN 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 749393523  142 NTFSVWFEHPVQVEQDTFYTVSAILDGNELSY 173
Cdd:pfam08005  78 DIFRVLFDEPVEIEPNVKYTASAKIKGPSSYY 109
 
Name Accession Description Interval E-value
PHR pfam08005
PHR domain; This domain is called PHR as it was original found in the proteins PAM, highwire ...
 69-173 3.72e-38

PHR domain; This domain is called PHR as it was original found in the proteins PAM, highwire and RPM. This domain can be duplicated in the highwire, PFAM and PRM sequence. The C-terminal region of the protein BTBD1 includes the PHR domain and is known to interact with Topoisomerase I, an enzyme which relaxes DNA supercoils.


Pssm-ID: 462339  Cd Length: 150  Bit Score: 127.74  E-value: 3.72e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749393523   69 HRFQSSAYRsnqWRYRGRC-DSIQFAVDKRIFIAGLGLYGSSCGKAEYSVKIELK------RQGVVLAQNLTKFVSDGCS 141
Cdd:pfam08005   1 NRFQSTGGG---WGYSGGSpDAIRFSVDRDIFLVGFGLYGSIGGPADYSVKIELIdgerweSLGEVLGENDTTFSSDGSN 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 749393523  142 NTFSVWFEHPVQVEQDTFYTVSAILDGNELSY 173
Cdd:pfam08005  78 DIFRVLFDEPVEIEPNVKYTASAKIKGPSSYY 109
 
Name Accession Description Interval E-value
PHR pfam08005
PHR domain; This domain is called PHR as it was original found in the proteins PAM, highwire ...
 69-173 3.72e-38

PHR domain; This domain is called PHR as it was original found in the proteins PAM, highwire and RPM. This domain can be duplicated in the highwire, PFAM and PRM sequence. The C-terminal region of the protein BTBD1 includes the PHR domain and is known to interact with Topoisomerase I, an enzyme which relaxes DNA supercoils.


Pssm-ID: 462339  Cd Length: 150  Bit Score: 127.74  E-value: 3.72e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749393523   69 HRFQSSAYRsnqWRYRGRC-DSIQFAVDKRIFIAGLGLYGSSCGKAEYSVKIELK------RQGVVLAQNLTKFVSDGCS 141
Cdd:pfam08005   1 NRFQSTGGG---WGYSGGSpDAIRFSVDRDIFLVGFGLYGSIGGPADYSVKIELIdgerweSLGEVLGENDTTFSSDGSN 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 749393523  142 NTFSVWFEHPVQVEQDTFYTVSAILDGNELSY 173
Cdd:pfam08005  78 DIFRVLFDEPVEIEPNVKYTASAKIKGPSSYY 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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