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Conserved domains on  [gi|814966907|gb|AKE42416|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Northiella haematogaster]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-319 8.11e-152

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 429.24  E-value: 8.11e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTY 80
Cdd:MTH00112  12 SLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00112  92 PTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLN 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00112 172 QTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSL 251

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSTKKPTSTLTPPITS 319
Cdd:MTH00112 252 AGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKKNTLTATLTT 330
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-319 8.11e-152

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 429.24  E-value: 8.11e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTY 80
Cdd:MTH00112  12 SLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00112  92 PTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLN 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00112 172 QTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSL 251

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSTKKPTSTLTPPITS 319
Cdd:MTH00112 252 AGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKKNTLTATLTT 330
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 3-287 5.71e-31

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 120.99  E-value: 5.71e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   3 ILGTTITITSNHWTMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLF-SSMTNAwFTGQWDISQL-- 78
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIaa 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  79 ------TYPP----SCLLLTTAIAIKLGLAPFHFWFPEVLQGSslttalllstlmklpPTTI------------------ 130
Cdd:COG1007  191 alaaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGA---------------PTPVtaflatapkiaafaallr 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 131 -LLLTSHSLNP---TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFYM--YTLMTT 202
Cdd:COG1007  256 lLVEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNL 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 203 SIFLIL-----NTTNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLL 277
Cdd:COG1007  336 GAFAVIlllsrKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415

                        330
                 ....*....|
gi 814966907 278 GLFFYLRLAY 287
Cdd:COG1007  416 SAYYYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 12-257 2.03e-25

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 102.78  E-value: 2.03e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   12 SNHWTMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQL-TYPPSC----- 84
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   85 -----LLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLM-KLPPTTILLLTS--HSLNPT---LLTTMSILSIAL 153
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  154 GGWMGLNQTQTRKILAFSSISHLGWMTMII----IYNPKLTLLTFYMYTLMTTSIFL-----ILNTTNTLKLSTLLTSWT 224
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 814966907  225 KTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQ 257
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 3-286 3.67e-24

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 101.95  E-value: 3.67e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907    3 ILGTTITITSNHWTMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTYP 81
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   82 PSC------------LLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILL-------LTSHSLNPTL 142
Cdd:TIGR01770 192 LSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  143 LTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFY--MYTLMTTSIFLIL------NTTN 212
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYifIYALMSLGAFGVLsllrsyKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 814966907  213 TLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLA 286
Cdd:TIGR01770 352 IEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-319 8.11e-152

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 429.24  E-value: 8.11e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTY 80
Cdd:MTH00112  12 SLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00112  92 PTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLN 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00112 172 QTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSL 251

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSTKKPTSTLTPPITS 319
Cdd:MTH00112 252 AGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKKNTLTATLTT 330
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-319 1.27e-128

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 370.67  E-value: 1.27e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTY 80
Cdd:MTH00135  12 SLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSH 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTtILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00135  92 PLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAPTNPTLLITLGLTSTLVGGWGGLN 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00135 171 QTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSL 250

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSTKKPTSTLTPPITS 319
Cdd:MTH00135 251 GGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQLTLPLAIST 329
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-319 3.92e-127

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 366.94  E-value: 3.92e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTY 80
Cdd:MTH00070  12 SLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTGEWTIMNMQT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00070  92 PLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLSTLIGGWGGLN 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00070 172 QTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSL 251

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSTKKPTSTLTPPITS 319
Cdd:MTH00070 252 GGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNKTNNLLSLTII 330
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-318 2.73e-112

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 329.11  E-value: 2.73e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTY 80
Cdd:MTH00105  12 TLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTITKLTN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00105  92 PTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLN 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00105 172 QTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSL 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLPPNPSN-KMK-QWSTKKPTSTLTPPIT 318
Cdd:MTH00105 252 GGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNmKMKwQFENTKPMTLLPTLII 331
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-313 2.09e-94

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 283.40  E-value: 2.09e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTY 80
Cdd:MTH00200  12 SLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGISEMLG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00200  92 PLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSVLVGGWGGLN 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00200 172 QTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSL 251

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSTKKPTSTL 313
Cdd:MTH00200 252 GGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSNSNLL 324
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-315 3.08e-88

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 267.95  E-value: 3.08e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTY 80
Cdd:MTH00041  12 SIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00041  92 TLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLN 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00041 172 QTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSL 251

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSTKKPTSTLTP 315
Cdd:MTH00041 252 GGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGV 326
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 2-319 4.63e-61

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 197.74  E-value: 4.63e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   2 LILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGqwdisqLTYP 81
Cdd:MTH00160  14 LIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLM------LFNN 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  82 PSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPttiLLLTSHSLNPTLLTTMSILSIALGGWMGLNQ 161
Cdd:MTH00160  88 ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAP---LILLSYLINNNFIIIIIILSAIIGAIGGLNQ 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 162 TQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSLA 241
Cdd:MTH00160 165 TSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLG 244

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 814966907 242 GLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLppNPSNKMKQWSTKKPTSTLTPPITS 319
Cdd:MTH00160 245 GLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLN--YNKNKWNLKKKKNKFSLILNFLSF 320
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 2-291 3.44e-51

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 171.99  E-value: 3.44e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   2 LILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISqltyp 81
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM----- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  82 pscLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPttILLLTSHSLNPTLLTT---MSILSIALGGWMG 158
Cdd:MTH00144  88 ---SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAP--LFLLSNFLDLYWLAYLlcvISVLSALVGSIGG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 159 LNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTlLTSWTKTPTLNATLMMTLL 238
Cdd:MTH00144 163 LNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKD-LGSLKPSYKTGLSIISLLL 241

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 814966907 239 SLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTI 291
Cdd:MTH00144 242 SLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL 294
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-299 4.69e-48

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 163.80  E-value: 4.69e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSmtnawfTGQWDISQLTY 80
Cdd:MTH00011  14 TMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSFPSLLK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00011  88 NITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMN 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00011 168 QTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSL 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYcSTITLPPNPSN 299
Cdd:MTH00011 248 GGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS 305
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 1-302 2.33e-42

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 148.67  E-value: 2.33e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   1 SLILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMtnAWFTGQWdisqlTY 80
Cdd:MTH00197   6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGS--LSFSNLY-----LS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPttILLLTSHSLNPTLLTTMSILSIALGGWMGLN 160
Cdd:MTH00197  79 LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGGIGGMN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSL 240
Cdd:MTH00197 157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 814966907 241 AGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMK 302
Cdd:MTH00197 237 GGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMK 298
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 3-287 5.71e-31

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 120.99  E-value: 5.71e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   3 ILGTTITITSNHWTMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLF-SSMTNAwFTGQWDISQL-- 78
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIaa 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  79 ------TYPP----SCLLLTTAIAIKLGLAPFHFWFPEVLQGSslttalllstlmklpPTTI------------------ 130
Cdd:COG1007  191 alaaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGA---------------PTPVtaflatapkiaafaallr 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 131 -LLLTSHSLNP---TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFYM--YTLMTT 202
Cdd:COG1007  256 lLVEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNL 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 203 SIFLIL-----NTTNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLL 277
Cdd:COG1007  336 GAFAVIlllsrKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415

                        330
                 ....*....|
gi 814966907 278 GLFFYLRLAY 287
Cdd:COG1007  416 SAYYYLRVVK 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 2-285 4.73e-28

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 111.66  E-value: 4.73e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   2 LILGTTITITSNHWTMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLTQAAASTLLLFS-------------SMTNA 67
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  68 WFTGQWDISQLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLltSHSLNPTLLTTMS 147
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILV--SIGLNVNILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 148 ILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMII----IYNPKLTLLTFYMYTLMTTSIFLILNTTNTLK-----LST 218
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFSIILALNVYKnliieFSG 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 814966907 219 LLtswTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRL 285
Cdd:MTH00196 240 LS---RRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
3-285 1.90e-27

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 111.45  E-value: 1.90e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   3 ILGTTITITSNHWTMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQL--- 78
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIaka 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  79 -----TYPP----SCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKL----PPTTILLLTSHSLNPT---L 142
Cdd:PRK05777 193 ladgsGNSLlllfGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwqqV 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 143 LTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFYM--YTLMTTSIF-LILNTTNTLKLS 217
Cdd:PRK05777 273 LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsaVLFYLlaYLFMTLGAFgVISLLRRKGGEA 352

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 814966907 218 TLLTSWT----KTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRL 285
Cdd:PRK05777 353 ESISDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 12-257 2.03e-25

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 102.78  E-value: 2.03e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   12 SNHWTMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQL-TYPPSC----- 84
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   85 -----LLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLM-KLPPTTILLLTS--HSLNPT---LLTTMSILSIAL 153
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  154 GGWMGLNQTQTRKILAFSSISHLGWMTMII----IYNPKLTLLTFYMYTLMTTSIFL-----ILNTTNTLKLSTLLTSWT 224
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 814966907  225 KTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQ 257
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 3-286 3.67e-24

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 101.95  E-value: 3.67e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907    3 ILGTTITITSNHWTMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTYP 81
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   82 PSC------------LLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILL-------LTSHSLNPTL 142
Cdd:TIGR01770 192 LSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  143 LTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFY--MYTLMTTSIFLIL------NTTN 212
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYifIYALMSLGAFGVLsllrsyKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 814966907  213 TLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLA 286
Cdd:TIGR01770 352 IEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 2-285 2.11e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 97.01  E-value: 2.11e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   2 LILGTTITITSNHWTMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDI----S 76
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  77 QLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTtmSILSIALGGW 156
Cdd:MTH00199 186 ILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIYGAI 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 157 MGLNQTQTRKILAFSSISHLGWMTMIIIYNP----KLTLLTFYMYTLMTTSIFLILNTTNTLK--LSTLLTSWTKTPTLN 230
Cdd:MTH00199 264 GALNQTKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSICSFSIILSLKLTKglIVEVSGLSRKNPVIA 343

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 814966907 231 ATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRL 285
Cdd:MTH00199 344 LTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 2-285 4.15e-21

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 92.90  E-value: 4.15e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   2 LILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQL--- 78
Cdd:COG0651  116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLaar 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  79 --TYPPS-----CLLLTTAIAIKLGLAPFHFWFPEVlqgsslttalllstlMKLPPT--------------------TIL 131
Cdd:COG0651  196 laELDPGlllaaFALLLVGFGIKAALFPLHFWLPDA---------------YPAAPSpvsallsglltkvgvyailrVLT 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 132 LLTSHSLNP---TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMII-IYNPK-LTLLTFYM--YTLMTTSI 204
Cdd:COG0651  261 LLFGADPALflgTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLgLGTPLgLAGALFHLlnHALAKALL 340

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 205 FL----ILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLF 280
Cdd:COG0651  341 FLaagaIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLA 420


                 ....*
gi 814966907 281 FYLRL 285
Cdd:COG0651  421 YFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 4-285 1.77e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 79.90  E-value: 1.77e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   4 LGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAI---------EATTKYFLTQAAASTLLLFSSMTNAWFTGQ-- 72
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNeg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  73 ------------WDISQLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLppTTILLLTSHSLNP 140
Cdd:MTH00198 279 mlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITS 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 141 TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMII-------IYNPKLTLLTFYMYTLMTTSIFLILNTTNT 213
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVsagtyesLQASWTYAVTYLVSALASFTVICTLEEFGT 436

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 214 L------------------KLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLS 275
Cdd:MTH00198 437 RtptsrqrdgsfgnynlvrRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSSLSIYYLVA 516

                        330
                 ....*....|....*..
gi 814966907 276 LLGL-------FFYLRL 285
Cdd:MTH00198 517 LFAIictcisaFYYIRI 533
ndhB CHL00049
NADH dehydrogenase subunit 2
 40-252 4.35e-13

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 69.65  E-value: 4.35e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  40 RAIEATTKYFLTQAAASTLLL--FSsmtnaWFTGQ-------WDI------SQLTYPPSCLL----LTTAIAIKLGLAPF 100
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVygFS-----WLYGLsggeielQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPF 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 101 HFWFPEVLQGSSLTTALLLSTLMKLP----PTTILLLTSHSLNP---TLLTTMSILSIALGGWMGLNQTQTRKILAFSSI 173
Cdd:CHL00049 234 HQWTPDVYEGSPTPVVAFLSVTSKVAasalATRIFDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKRMLAYSSI 313

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 174 SHLGWMTMIII-------YNPKLTLLTFYMYTLMTT--SIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLP 244
Cdd:CHL00049 314 GQIGYVIIGIIvgdsndgYASMITYMLFYIFMNLGTfaCIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGIP 393


                 ....*...
gi 814966907 245 PLTGFLPK 252
Cdd:CHL00049 394 PLAGFFGK 401
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 27-300 1.51e-11

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 64.72  E-value: 1.51e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  27 LAIIP---LISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQW-----DISQLTYPPS-----CLLLTTAIAI 93
Cdd:COG1008  142 LMLIPmyfLIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfdiaELAAAPLPLTaqlllFLAFFIAFAV 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  94 KLGLAPFHFWFPEVLQGSSlttalllstlmklPPTTILL---------------------LTSHSLNPTLLTtMSILSIA 152
Cdd:COG1008  222 KVPMFPFHTWLPDAHVEAP-------------TAGSVLLagvllkmggygllrfalplfpEASAYFAPLLAA-LGVIGII 287

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 153 LGGWMGLNQTQTRKILAFSSISHLGWMTM-IIIYNPK-LTLLTFYM--YTLMTTSIFLIL----NTTNTLKLSTLLTSWT 224
Cdd:COG1008  288 YGALVALAQTDLKRLIAYSSVSHMGFVLLgIFALNPLgLQGAVLQMvsHGLITAALFLLVgvlyDRTHTRDIADLGGLAK 367

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 814966907 225 KTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKqemttTATAIALLSLLGLFF---YLRLAYCSTITLPPNPSNK 300
Cdd:COG1008  368 RMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQ-----VNPWLAILAALGLILtaaYLLWMYQRVFFGPLKEELA 441
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 22-287 3.18e-11

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 63.74  E-value: 3.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  22 LEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFS-SMTNAwFTGQWDISQLT--YPPSCLLLT------TAIA 92
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLAgaLAENPTVVTafgfvlLALA 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  93 IKLGLAPFHFWFPE-----------VLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMsILSIALGGWMGLNQ 161
Cdd:PRK08375 214 LKAAVFPLHTWLPRaypaappvvtaLLSGLVTKVAVYALIRIYFTVFGGDFRFALGLGWLLAVLA-LLSMLVGSLAALGQ 292

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 162 TQTRKILAFSSISHLGWMTMIIIYNPKLTLL--TFYM--YTLMTTSIFL----ILNTTNTLKLSTLLTSWTKTPTLNATL 233
Cdd:PRK08375 293 DDVKRVLAYSTVSQMGYILLGLALLTPLALAagLLHLlhHALMKGALFLaagaIEVTYGTRRLSELSGLGRRMPLTAAAF 372

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 814966907 234 MMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAY 287
Cdd:PRK08375 373 AVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
39-252 3.54e-10

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 60.84  E-value: 3.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  39 PRAIEATTKYFLTQAAASTLLLF-SSMTNAWFTGQWDIS----QLTYPPSCLLLTT------AIAIKLGLAPFHFWFPEV 107
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSaialALITSPSLGLALAlvfviaGIAFKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 108 LQGSSLTTALLLSTLMKLPPTTI---LLLTSHSLNPT----LLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMT 180
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAGFALairLLVTAFPSFDEqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 181 MIIIYNPK--LTLLTFYM--YTLMT----TSIFLILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPK 252
Cdd:PRK02504 317 IGLVAGTEagYASMVFYLlaYLFMNlgafACVILFSLRTGTDQISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 39-281 1.26e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 58.80  E-value: 1.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   39 PRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQW----DISQLTYPPSC-----LLLTTAIAIKLGLAPFHFWFPEV-L 108
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGTfdllELLNLPLPFGVqtwlfLAFFIAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  109 QGSSLTTALLLSTLMKLPPTTILLL-------TSHSLNPtLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTM 181
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTYGFLRFnlplfpdASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  182 IIIYNPKLTLL--TFYMYT--LMTTSIFLILNT----TNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKW 253
Cdd:TIGR01972 311 GIFSFNELGISgaVFQMIShgLITAALFLLVGVlyerAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEF 390

                         250       260
                  ....*....|....*....|....*...
gi 814966907  254 LIIQELTKqemttTATAIALLSLLGLFF 281
Cdd:TIGR01972 391 LILLGSFK-----VNPVVAFLAALGIVL 413
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 23-287 3.17e-09

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 57.70  E-value: 3.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  23 EINTLA---IIPLISKshhpRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQ----LTYPPS-------CLLLT 88
Cdd:PRK08668 128 EIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADisqgLINDTStgfalivFLFLL 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  89 TAIAIKLGLAPFHFWFPE-----------VLQGSSLTT-ALLLSTLMKLPPTTILLLT-----SHSLNPTLLTTMSILSI 151
Cdd:PRK08668 204 AFGVAKAGIFPLHVWAPDayseapqsfsaVLSGQLSKLgAYGFLLVLYVLPGTKLFSEfgtyrGVPLFNYILAWLGNISI 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 152 ALGGWMGLNQTQTRKILAFSSISHLGWmtmIIIYNPKLTLLTF-------YMYTLMTTSIFLILNT----TNTLKLSTLL 220
Cdd:PRK08668 284 IVGTLMAILQEDIKKLIAYSSVANGGY---ILVGLGLGTSLGFagglfhvFNHALFKGLFFLIFAAviyrTGTTKISEMG 360

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 814966907 221 TSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAY 287
Cdd:PRK08668 361 GLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 37-287 3.78e-09

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 57.47  E-value: 3.78e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  37 HHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQL-----------TYPPSCLLLTTAIAIKLGLAPFHFWFP 105
Cdd:COG1009  156 EKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELlaaaptilsspLLTLILLLLLLGAFGKSAQFPLHFWLP 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 106 EVLQGsslttalllstlmklpPTTI---------------LLLTSH---SLNPTLLTTMSILSIA---LGGWMGLNQTQT 164
Cdd:COG1009  236 DAMEG----------------PTPVsallhaatmvkagvyLLARLSplfALSPVWLTVVAIIGAItalFAALIALAQTDI 299

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 165 RKILAFSSISHLGWMTMIIiynpKLTLLTFYMYTLMTTSIF---LIL---------NTTNTLKLSTLltsWTKTPTLNAT 232
Cdd:COG1009  300 KRVLAYSTVSQLGYMFLAL----GVGAYVAALFHLLTHAFFkalLFLgagsvihatGTRDIRKMGGL---RKKMPITAIT 372

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 814966907 233 LMMTLLSLAGLPPLTGFLPKWLIIQE-LTKQEMTTTATAIALL-SLLGLFFYLRLAY 287
Cdd:COG1009  373 FLIGALSLAGIPPFAGFFSKEAILEAaLEAGGLGPLLLAVALLgAFLTAFYSFRLFF 429
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 22-255 2.43e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 55.10  E-value: 2.43e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  22 LEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSmtnAWFTGQWDI-------SQLTYPPSCL------LL 87
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTlnmaylaVKMSENPTVVakialaLF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  88 TTAIAIKLGLAPFHFW----FPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPT----LLTTMSILSIALGGWMGL 159
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWlpdaYPAAPSSISAMLLVIKQAGLYALARVLFSIYGPAINLAtvgwVIIILGCLTMFVGVAMAV 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 160 NQTQTRKILAFSSISHLGWMTM---IIIYNPKLTLLTFYMYTLMTTSIFLILN--------------------TTNTLKL 216
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMLLglgVGLAALGDPAMASYGEIALAGGIYHIVNhalykallfltagaviyetgTRNLNEL 386

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 814966907 217 STLLTSWTKTptlNATLMMTLLSLAGLPPLTGFLPKWLI 255
Cdd:PRK08376 387 GGLARTMPKT---TIAFLIGAAAIVGLPPFNGFASKWLI 422
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 70-252 1.65e-07

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 52.62  E-value: 1.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  70 TGQWDISQL-TYPPSCLLLTTAIAI-------KLGLAPFHFWFPEVLQGSSLTTALLLSTLM---------KLPPTtilL 132
Cdd:PRK12644 184 AGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMvkagiylvaRLAPG---F 260

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 133 LTSHSLNPTLLTtMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMII-IYNPKLTLLTFYM---YTLMTTSIFL-- 206
Cdd:PRK12644 261 ADVPVWRPTVLV-LGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVgIGTRDAALAGLAMllaHALFKAALFLvv 339

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 814966907 207 --ILNTTNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPK 252
Cdd:PRK12644 340 giIDHSTGTRDIRKLSGLGRRQPVLAVVAALAAASMAGLPPLLGFVAK 387
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 9-281 2.84e-07

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 51.85  E-value: 2.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   9 TITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFL------TQAAASTLLLFSSMTNAWFTGQWDI--SQLTY 80
Cdd:PRK06458 124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDGEMAIlwTELLK 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  81 PPSCL---LLTTAIAI-------KLGLAPFHFWFPE-----------VLQGSSLTTALLLSTLMKLppttILLLTSHSLN 139
Cdd:PRK06458 204 HASLLdptLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYI----LIDAAIGSDF 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 140 P-TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKL----TLLTFYMYTLMTTSIFL----ILNT 210
Cdd:PRK06458 280 PgRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLgifaALLHMLNHSLTKSAIFFasgnVLQK 359

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 814966907 211 TNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMttTATAIALLSLLGLFF 281
Cdd:PRK06458 360 YGTRDINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILTAGLARGP--LLIAILLLLLLTLAF 428
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
141-314 3.04e-06

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 48.41  E-value: 3.04e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 141 TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTM-IIIYNPK-LTLLTFYMYTLMT--TSIFLILNTTNTLKL 216
Cdd:PRK12663 273 PLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILLgLALGTPAgINGAIFYLVHDMVvkTALFLIAGSLVRLTG 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 217 STLLTS----WTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQ-ELTKQEMTTTATAIA--LLSLLGLFFYLRLAYCS 289
Cdd:PRK12663 353 YRSLQYlgglYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQgALDNGAYILLALMLItsLITMYSLFRIFFLAYWG 432

                        170       180
                 ....*....|....*....|....*
gi 814966907 290 TITLPPNPSNKMKQWsTKKPTSTLT 314
Cdd:PRK12663 433 DKDGEEVNFKPIPLY-RKLPLSILA 456
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 141-285 3.35e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 48.41  E-value: 3.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 141 TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTM-IIIYNPKLTLLTFYmYT----LMTTSIFL-------IL 208
Cdd:PRK07691 276 YLILILALLTIIFGVIGAVAYFDIKKIIIYNIMIAVGVILVgVAMMTESGMIGAIY-YLihdmIVKAALFLligimikIT 354

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 814966907 209 NTTNTLKLSTLLTSWtktPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRL 285
Cdd:PRK07691 355 GTTDLKKMGGLIKRY---PVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLVLYSVIKI 428
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 141-285 4.88e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 47.81  E-value: 4.88e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 141 TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMY----TLMTTSIFLILNTT----N 212
Cdd:PRK12662 280 NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFMVSGSIsyhfG 359

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 814966907 213 TLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRL 285
Cdd:PRK12662 360 TTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVLLVGSGLSVIYVWKI 432
PRK12650 PRK12650
DUF4040 family protein;
87-252 5.61e-06

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 48.12  E-value: 5.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  87 LTTAIAIKLGLA--------PFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSL--NPT---LLTTMSILSIAL 153
Cdd:PRK12650 206 LTTVVAVLIAVAaftksaqfPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFhdVAVwnwLLIIVGMITALM 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 154 GGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYT----LMTTSIFLIL----NTTNTLKLSTLLTSWTK 225
Cdd:PRK12650 286 GAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTlahaLFKSSLFMLIgvvdHQAGTRDIRRLGSLWRR 365

                        170       180
                 ....*....|....*....|....*..
gi 814966907 226 TPTLNATLMMTLLSLAGLPPLTGFLPK 252
Cdd:PRK12650 366 MPFTFVSVTIAALSMAAVPPLFGFVSK 392
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 27-256 1.09e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 46.73  E-value: 1.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  27 LAIIP---LISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWF----TGQWDISQLTYPPSCLLLTT--------AI 91
Cdd:PRK05846 142 AMLIPmyfLIGVWGGKNRIYAATKFFLYTLLGSLLMLVAIIYLVVVyynaTGTFDIADLLNLPLPPGVQYwlflaffiAF 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  92 AIKLGLAPFHFWFPE-----------VLQGSSLTTALLLSTLMKLPpttILLLTSHSLNPtLLTTMSILSIALGGWMGLN 160
Cdd:PRK05846 222 AVKMPMFPLHTWLPDahvqaptagsvLLAGILLKMGAYGLLRFSLP---LFPDASHEFAP-IIITLGVIAIIYGALVALA 297

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 161 QTQTRKILAFSSISHLGWMTM-IIIYNPK-LTLLTFYM--YTLMTTSIFLILNT----TNTLKLSTLLTSWTKTPTLNAT 232
Cdd:PRK05846 298 QTDIKKLIAYSSISHMGFVTLgIFAGNQLgIQGAIFQMisHGLSSAALFLLVGVlydrLHTRDIADYGGLAKVMPVLAAF 377

                        250       260
                 ....*....|....*....|....
gi 814966907 233 LMMTLLSLAGLPPLTGFLPKWLII 256
Cdd:PRK05846 378 FLFFAMASLGLPGTSGFVGEFLIL 401
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 80-278 1.25e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 46.84  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  80 YPPSCLLLTTAIAIKLGLAPFHFWFPEVlqgsslttalllstlMKLP-PTTILLltsHS-------------LNP----- 140
Cdd:PRK12647 194 YLAILLLVLGGAFTKSAQFPFHFWLPNA---------------MEAPtPVSAYL---HSatmvkagiyllarLNPvlggt 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 141 ----TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMY----TLMTTSIFLILNT-- 210
Cdd:PRK12647 256 plwqTILPLFGGLTMLTGALLAVRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFlvahSLYKGALFMVAGIid 335

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 211 --TNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTkqEMTTTATAIALLSLLG 278
Cdd:PRK12647 336 heTGTRDITKLGGLRRAMPITAAAALLAALSMAGLPPLFGFLAKELIYEALL--EAPLWSLILTVAAVLG 403
PRK06459 PRK06459
hydrogenase 4 subunit B; Validated
 3-259 1.27e-05

hydrogenase 4 subunit B; Validated


Pssm-ID: 235806 [Multi-domain]  Cd Length: 585  Bit Score: 46.71  E-value: 1.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   3 ILGTTITITSNHWTM---AWTGLEINTLAIIPLISKSHHPRAIeattkyFLTQAAASTLLLFSSMTNAWF-TGQWDISQL 78
Cdd:PRK06459  82 ILGMAIVLTSDNYLLflaGWEIMTIPSYVAIALTKKNKRPAFV------FMAFGELSTVLILAGFAWAFIiSGTTNFSYL 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  79 TYPPSCLLLTTAIAIKLGLAPFHF--WFPEVLQGSSLTTALLLSTLMKLPP----TTILLLTSHSLNPTL---LTTMSIL 149
Cdd:PRK06459 156 PSPVPLILASFGFIIKMGMMPFLVseWLPIAHGNAPSNFSAILSATMTLMGvygiLKMTILTQTIPIGYFgltILAIGAF 235

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 150 SIALGGWMGLNQTQTRKILAFSSISHLGWM-----TMIIIYNPKLTLLTFYMYTLMT---------TSIFLILNTTNTLK 215
Cdd:PRK06459 236 SILFGALYAYVSENVKGLLAFSTIENNGAIlvalgLYMVTKQLITSIEHFSLITVILysfahsvakTGLFLSSGLQEKQS 315

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 814966907 216 LSTLLTSWTKTPTLNATLMMtlLSLAGLPPLTGFLPKWLIIQEL 259
Cdd:PRK06459 316 ITYSKKIRNRWIELGLTLLA--SSLSGLLPNIGGVASWLLLESL 357
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
141-313 7.36e-05

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 44.25  E-value: 7.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 141 TLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLT----LLTFYMYTLMTTSIFL----ILNTTN 212
Cdd:PRK06277 267 GVLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGivagIFHAINHVIYKSALFLgagiVSYRTK 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 213 TLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLGLFFYLRLAYcsTIT 292
Cdd:PRK06277 347 TSNLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQAAMQANMPELAIIMIIVSIGTFVSMMKAFY--LIY 424

                        170       180
                 ....*....|....*....|.
gi 814966907 293 LPPNPsNKMKQWSTKKPTSTL 313
Cdd:PRK06277 425 LKPKP-EELEYKNKKVPKYAV 444
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 85-257 8.11e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 44.19  E-value: 8.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  85 LLLTTAIAIKLGLAPFHFWFPE-----------VLQGSSLTTALLLSTLmklppTTILLLTSHSLNpTLLTTMSILSIAL 153
Cdd:PRK12665 213 AVLLVAFGIKAAVFPLSFWLPDsyptapapvtaVFAGLLTKVGVYAIIR-----THTLLFPGGGLD-TLLMVVALLTMVV 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 154 GGWMGLNQTQTRKILAFSSISHLGWMTM-IIIYNPK-LTLLTFYM--YTLMTTSIFLILN-------TTNTLKLSTLLTS 222
Cdd:PRK12665 287 GILGAIAQSDIKRLLSFTLVSHIGYMVFgIALSTVAgLSGAIYYVahHITVQTTLFLVVGlierqagSSSLRRLGGLAKA 366

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 814966907 223 wtkTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQ 257
Cdd:PRK12665 367 ---SPLLAVLFFVPALNLGGIPPFSGFIGKVALLE 398
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 22-260 2.84e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 42.25  E-value: 2.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  22 LEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQL-TYPPSCL-LLTTAIAIKLGLAP 99
Cdd:PRK07234 123 LEVLSIATFLLVAYPRTDRAIWVGLRYLFYSNVAMLFYLIGAVLVYQANGTFAFSGLaTADPEAFaLIALGLLVKGGIFV 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 100 FHFWFPEVlqgsslttalllstlMKLPPTTILLLTS-----------------HSLNPTLLTTMSILSIALGGWMGLNQT 162
Cdd:PRK07234 203 SGLWLPLT---------------HSEAEPPVSALLSgvvvkagvfplvrcaldVPGLDLIVRIFGVGTALLGVLFALLEK 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 163 QTRKILAFSSISHLGWmtmiIIYNPKLTLLTFYMYTLMTTSIFLI---LNTTNTLKL-STLLTSWTKTPtlnatLMMTLL 238
Cdd:PRK07234 268 DLKRMLAFSTISQLGF----ILAAPLVGGLYALAHGLVKSTLFLCagaLPSRNFTELiSQMLGIGKWIP-----LTMASF 338

                        250       260
                 ....*....|....*....|..
gi 814966907 239 SLAGLPPLTGFLPKWLIIQELT 260
Cdd:PRK07234 339 SIAGFPLLAGFVSKVLTLKNLL 360
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 37-252 3.12e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 42.51  E-value: 3.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  37 HHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTGQWDISQLTYPPSC--------LLLTTAIAIKLGLA------PFHF 102
Cdd:PRK12649 156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELienikghpLFLITLILIFIGAAaksaqgPFYI 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 103 WFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPT-----LLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLG 177
Cdd:PRK12649 236 WLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSGTeawfiLVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQLA 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 178 WMTMIIIYN----PKLTLL--TFYMYTLMTTSIFLIL---------NTTNTLKLSTLLTSWTKTPTLNAtlmMTLLSLAG 242
Cdd:PRK12649 316 YLMTMYGYTtyhePGLGVAaaTFHLLNHATFKACLFLvagivaheaATRDIRKLGGLRKEMPITFIVAS---IAALAMAG 392

                        250
                 ....*....|
gi 814966907 243 LPPLTGFLPK 252
Cdd:PRK12649 393 IPPLNGFLSK 402
PRK12646 PRK12646
DUF4040 family protein;
80-282 3.32e-04

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 42.43  E-value: 3.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  80 YPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTIL-----LLTSHSLNPTLLTTMSILSIALG 154
Cdd:PRK12646 209 FIPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLfrftpLLGLSNMYIYIVTFVGLITMLFG 288

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 155 GWMGLNQTQTRKILAFSSISHLGW-MTMI-----IIYNPKLTLLTFY-------MYTLMTTSIF---------LILNTTN 212
Cdd:PRK12646 289 SITALKQWDLKGILAYSTISQLGMiMAMVgigggYAQHQQDAIASIYvfvlfaaLFHLMNHAIFkcalfmgvgIIDHEAG 368

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 814966907 213 TLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTK--------QEMTTTATAIALLSLLGLFFY 282
Cdd:PRK12646 369 TRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQtgqlsqfsLISMIIIVFIGVIASIFTFTY 446
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 90-256 3.89e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 41.83  E-value: 3.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  90 AIAIKLGLAPFHFWFPE-----------VLQGSSLTTALLLSTLMKLPpttILLLTSHSLNPTLLtTMSILSIALGGWMG 158
Cdd:MTH00226 239 AMAVKIPIFPFHIWLPKahveapvagsvLLAGILLKLGGYGLVRLSWP---ILPLGAQNLAPAVI-AMGIVGIVYGSFAT 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 159 LNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTL---MTTSIFLILNTTNTLKLSTLLTSWTK-----TPTLN 230
Cdd:MTH00226 315 CRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGLTGSIFIMLahgIVSSLLFILVTILYDRHHTRLIKYYRglsitMPIWG 394

                        170       180
                 ....*....|....*....|....*.
gi 814966907 231 ATLMMTLLSLAGLPPLTGFLPKWLII 256
Cdd:MTH00226 395 TIMIVTSLANVAVPPSGNFIGEYLSI 420
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 2-284 1.41e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 40.12  E-value: 1.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907   2 LILGTTITITSNHWTMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAA------STLLLFSSMTNAWFTGQWDI 75
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  76 SQLT-----YPPSCLLLT-----TAIAIKLGLAPFHFWFPEV-LQGSSLTTALLLSTLMKLPPTTILLLTS-------HS 137
Cdd:PRK08676 191 TELAahaslLSPSVLGASflfifIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRLSAllrqsgaAE 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 138 LNPTLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFYM--YTLMTTSIF----LILN 209
Cdd:PRK08676 271 QFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALfwMLFHMlaHSLVKSGLFfsagILHR 350

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 814966907 210 TTNTLKLSTLLTSWTKTPTLNATLMMTLLSLAGLPPLTGFLPKWLIIQELTKQEMTTTATAIALLSLLG---LFFYLR 284
Cdd:PRK08676 351 QYRSDRFDRIFDVFRLQPVAAWGVILGSAAIIGMPPFPLFLSKFFILLQLGGISVWLVLAVLLLLLLAAssfAIFLLK 428
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 93-261 2.01e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 39.08  E-value: 2.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  93 IKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLttmsILSIALGGWMGLNQTQTRKILAFSS 172
Cdd:MTH00091  69 MKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLL----LFGLLICFFQMFLLKSYKNLLILSS 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 173 ISHLGWMTMIIIYNPKLTLLTFYMYTLMttsIFLILNttntlklstlltSWTKTPTLNATLMMTLLSLAGLPPLTGFLPK 252
Cdd:MTH00091 145 TESFNWLILSFFFSFFNVFFLFFYYFLL---MLFLIP------------KFNNVNKLNFVSWETLLVFMNLPFSVTFFVK 209


                 ....*....
gi 814966907 253 WLIIQELTK 261
Cdd:MTH00091 210 IFSLSEILK 218
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
27-255 2.33e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 39.30  E-value: 2.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  27 LAIIPL---ISKSHHPRAIEATTKYFLTQAAASTLLLFSSMTNAWFTG--QWDISQL---TYPPSCLLLTTA-----IAI 93
Cdd:PRK06473 138 LELIPLyllIAIWGGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGasSFDYEPLrshTLPLSTQLLLLApilvgFGI 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  94 KLGLAPFHFWFPEV-LQGSSLTTALLLSTLMKLPPTTIL------LLTSHSLNPTLLTTMSILSIALGGWMGLNQTQTRK 166
Cdd:PRK06473 218 KIPLVPFHTWLPDAhVEASTPVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASCAIAQKDMKK 297

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 167 ILAFSSISHLGWMTMIIIYNPKLTLL--TFYMYT--LMTTSIFLIL-------NTTNTLKLSTLLTSWTKTPTLNATLMM 235
Cdd:PRK06473 298 MVAYSSIGHMGYILLAAAAATPLSILaaVFQMIShgLISALLFLLVgvvykktGSRDVDVLRGLLNPERGLPITGSLMIL 377

                        250       260
                 ....*....|....*....|
gi 814966907 236 TLLSLAGLPPLTGFLPKWLI 255
Cdd:PRK06473 378 GVMASAGIPGMVGFIAEFLV 397
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 100-257 4.88e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 38.40  E-value: 4.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 100 FHFWFPEVLQGSSLTTALLLSTLMKLPPTTIL-----LLTSHSLNPTLLTTMSILSIALGGWMGLNQTQTRKILAFSSIS 174
Cdd:MTH00032 244 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLMirsfpLFEKAPLTLLIITIFGALTAFFAATVGLVQNDLKKVIAYSTCS 323

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907 175 HLGWMTMIIIYNPKLTLLTFYMY------TLMTTSIFLILNTTNT-----LKLSTLLTSWTKTPTLnatLMMTLLSLAGL 243
Cdd:MTH00032 324 QLGYMVLIIGIEGSHNVGLFHLVnhaffkALLFLSAGSVIHSTTVdeqdmRKMGGLIHSIPFTYTM---MLIGSFSIMGL 400

                        170
                 ....*....|....
gi 814966907 244 PPLTGFLPKWLIIQ 257
Cdd:MTH00032 401 PYLTGFYSKDLILE 414
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 44-177 9.66e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 37.70  E-value: 9.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 814966907  44 ATTKYFLTQAAASTLLLFSSMTNAWFTGQ--WDISQLT---YPPSCLLLT-----TAIAIKLGLAPFHFWFPE------- 106
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGaksYPLALELLLyagflIAFGVKLPIFPLHTWLPDahgeasa 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 814966907 107 ----VLQGSSLTTALLLSTLMKLPpttiLLLTSHSLNPTLLTTMSILSIALGGWMGLNQTQTRKILAFSSISHLG 177
Cdd:PRK12561 218 pvsmILAGVLLKMGGYALIRFNVQ----MLPDAHVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMG 288
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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