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Conserved domains on  [gi|960498838|gb|ALR85541|]
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NADH dehydrogenase subunit I, partial (mitochondrion) [Betiscoides meridionalis]

Protein Classification

complex I subunit 1 family protein( domain architecture ID 103)

complex I subunit 1 family protein similar to NADH dehydrogenase subunit 1, which is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

EC:  7.1.1.-
Gene Ontology:  GO:0016655|GO:0016020
PubMed:  23417064|24059520
SCOP:  4005664

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06076 super family cl00469
NADH-quinone oxidoreductase subunit NuoH;
6-104 6.50e-44

NADH-quinone oxidoreductase subunit NuoH;


The actual alignment was detected with superfamily member MTH00193:

Pssm-ID: 469782  Cd Length: 306  Bit Score: 144.14  E-value: 6.50e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   6 LFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFS 85
Cdd:MTH00193   1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                         90
                 ....*....|....*....
gi 960498838  86 LMISLFVWPIFPYLTYMCS 104
Cdd:MTH00193  81 LFLSLLIWLIYPYLFNLIS 99
 
Name Accession Description Interval E-value
ND1 MTH00193
NADH dehydrogenase subunit 1; Provisional
 6-104 6.50e-44

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177241  Cd Length: 306  Bit Score: 144.14  E-value: 6.50e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   6 LFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFS 85
Cdd:MTH00193   1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                         90
                 ....*....|....*....
gi 960498838  86 LMISLFVWPIFPYLTYMCS 104
Cdd:MTH00193  81 LFLSLLIWLIYPYLFNLIS 99
NADHdh pfam00146
NADH dehydrogenase;
14-98 1.16e-21

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 85.99  E-value: 1.16e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   14 VLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFSLMISLFVW 93
Cdd:pfam00146   3 LLLLVPLLLAVAFLTWAERKVLARMQRRIGPNRVGPFGLLQPFADALKLLFKEDIIPAGADKFLFLLAPIIAFIPALLAF 82


                  ....*
gi 960498838   94 PIFPY 98
Cdd:pfam00146  83 AVIPF 87
NuoH COG1005
NADH:ubiquinone oxidoreductase subunit 1 (chain H) [Energy production and conversion]; NADH: ...
 5-98 1.74e-20

NADH:ubiquinone oxidoreductase subunit 1 (chain H) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 1 (chain H) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440629  Cd Length: 329  Bit Score: 83.26  E-value: 1.74e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   5 DLFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVF 84
Cdd:COG1005    7 PLLITLIKALVILVFLLLLAAYLTWAERKVLARMQDRIGPNRVGPFGLLQPLADGLKLLFKEDIIPAGADKFLFLLAPIL 86

                         90
                 ....*....|....
gi 960498838  85 SLMISLFVWPIFPY 98
Cdd:COG1005   87 AFIPALLAFAVIPF 100
 
Name Accession Description Interval E-value
ND1 MTH00193
NADH dehydrogenase subunit 1; Provisional
 6-104 6.50e-44

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177241  Cd Length: 306  Bit Score: 144.14  E-value: 6.50e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   6 LFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFS 85
Cdd:MTH00193   1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                         90
                 ....*....|....*....
gi 960498838  86 LMISLFVWPIFPYLTYMCS 104
Cdd:MTH00193  81 LFLSLLIWLIYPYLFNLIS 99
ND1 MTH00225
NADH dehydrogenase subunit 1; Provisional
 8-101 2.21e-35

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214465  Cd Length: 305  Bit Score: 122.07  E-value: 2.21e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   8 MFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFSLM 87
Cdd:MTH00225   2 SFLLKFLIMLICLLLSVAFYTLLERKVLGYIQLRKGPNKVGLMGLPQPFADALKLFTKEQTKPQLSNKLPYYIAPILSLI 81

                         90
                 ....*....|....
gi 960498838  88 ISLFVWPIFPYLTY 101
Cdd:MTH00225  82 LSLILWSLYPSMFS 95
ND1 MTH00143
NADH dehydrogenase subunit 1; Provisional
 11-99 7.49e-32

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177201  Cd Length: 307  Bit Score: 113.04  E-value: 7.49e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838  11 LNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFSLMISL 90
Cdd:MTH00143   5 LSSVFTYLCVLLAVAFFTLLERKGLGYFQIRKGPNKVGLMGLPQPLADAVKLFTKEFVKPTMSNKFPFFLAPCLSLILAL 84


                 ....*....
gi 960498838  91 FVWPIFPYL 99
Cdd:MTH00143  85 LLWQLYPSY 93
ND1 MTH00195
NADH dehydrogenase subunit 1; Provisional
 6-99 3.98e-25

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214452  Cd Length: 307  Bit Score: 95.58  E-value: 3.98e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   6 LFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFS 85
Cdd:MTH00195   1 WMISVIHFLIQIVPVLLAVAFFTLLERKILGYIQLRKGPNKVGPYGLLQPIADAVKLFIKEPVKPSTSSLWLFFFAPVLA 80

                         90
                 ....*....|....
gi 960498838  86 LMISLFVWPIFPYL 99
Cdd:MTH00195  81 LALALILWVPIPSP 94
ND1 MTH00218
NADH dehydrogenase subunit 1; Provisional
 11-97 1.62e-24

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214463  Cd Length: 311  Bit Score: 93.82  E-value: 1.62e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838  11 LNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFSLMISL 90
Cdd:MTH00218   6 INLLLYILPVLLAVAFLTLLERKVLGYMQLRKGPNVVGPYGLLQPIADGVKLFIKEPIRPSTSSPFLFLLAPILALTLAL 85


                 ....*..
gi 960498838  91 FVWPIFP 97
Cdd:MTH00218  86 LLWMPLP 92
ND1 MTH00216
NADH dehydrogenase subunit 1; Provisional
 2-98 1.94e-24

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 164761  Cd Length: 327  Bit Score: 94.03  E-value: 1.94e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   2 MLYDLFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFS 81
Cdd:MTH00216   1 MMVFIIFYLIKILIIIVPLLIAVAYLTLAERKVLGYMQARKGPNVVGVYGLLQPFADGVKLFTKEMVIPHHANLFVYIVA 80

                         90
                 ....*....|....*..
gi 960498838  82 PVFSLMISLFVWPIFPY 98
Cdd:MTH00216  81 PVLSFTLALIVWGVIPY 97
ND1 MTH00111
NADH dehydrogenase subunit 1; Provisional
 6-97 2.33e-24

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214422  Cd Length: 323  Bit Score: 93.81  E-value: 2.33e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   6 LFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFS 85
Cdd:MTH00111   4 LLLNLINPLLYIIPILIAVAFLTLLERKILGYMQLRKGPNIVGPFGLLQPIADGVKLFIKEPIRPSTSSPILFTLTPILA 83

                         90
                 ....*....|..
gi 960498838  86 LMISLFVWPIFP 97
Cdd:MTH00111  84 LLLALTIWTPLP 95
ND1 MTH00104
NADH dehydrogenase subunit 1; Provisional
 8-97 2.97e-24

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177166  Cd Length: 318  Bit Score: 93.15  E-value: 2.97e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   8 MFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFSLM 87
Cdd:MTH00104   1 MFMINILLLIIPILLAVAFLTLVERKVLGYMQLRKGPNIVGPYGLLQPFADAMKLFTKEPLRPLTSSTTMFIIAPILALT 80

                         90
                 ....*....|
gi 960498838  88 ISLFVWPIFP 97
Cdd:MTH00104  81 LALTMWIPLP 90
ND1 MTH00010
NADH dehydrogenase subunit 1; Validated
 9-98 4.16e-24

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 164586  Cd Length: 311  Bit Score: 92.92  E-value: 4.16e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   9 FSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFSLMI 88
Cdd:MTH00010   5 FFISILLSYVMALLAMAFYTLLERKALGYFQLRKGPNKVGLAGIPQPFADAIKLFTKEQTKPSPANITPFLGAPMMSLIL 84

                         90
                 ....*....|
gi 960498838  89 SLFVWPIFPY 98
Cdd:MTH00010  85 ALLLWSLYPH 94
ND1 MTH00040
NADH dehydrogenase subunit 1; Validated
 4-97 8.04e-24

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 214409  Cd Length: 323  Bit Score: 92.35  E-value: 8.04e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   4 YDLFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPV 83
Cdd:MTH00040   1 MSVILFLINLLSFIVPVLLAVAFLTLVERKVLGYMQFRKGPNVVGPYGLLQPFADGLKLFIKETLKPSNASPYLFFFSPV 80

                         90
                 ....*....|....
gi 960498838  84 FSLMISLFVWPIFP 97
Cdd:MTH00040  81 LFLFLALLLWSLIP 94
ND1 MTH00071
NADH dehydrogenase subunit 1; Provisional
 6-97 1.75e-23

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214418  Cd Length: 322  Bit Score: 91.22  E-value: 1.75e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   6 LFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFS 85
Cdd:MTH00071   4 LISLIINPLLYIIPVLLAVAFLTLVERKVLGYMQLRKGPNIVGPMGLLQPIADGLKLFIKEPIRPSTSSQILFILMPTMA 83

                         90
                 ....*....|..
gi 960498838  86 LMISLFVWPIFP 97
Cdd:MTH00071  84 LTLALIIWTPLP 95
ND1 MTH00134
NADH dehydrogenase subunit 1; Provisional
 2-97 1.97e-23

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177192  Cd Length: 324  Bit Score: 91.21  E-value: 1.97e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   2 MLYDLFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFS 81
Cdd:MTH00134   1 MLSTLITHIINPLAYIVPVLLAVAFLTLLERKVLGYMQLRKGPNIVGPYGLLQPIADGVKLFIKEPVRPSTSSPFLFLAT 80

                         90
                 ....*....|....*.
gi 960498838  82 PVFSLMISLFVWPIFP 97
Cdd:MTH00134  81 PMLALTLALTLWAPMP 96
ND1 MTH00054
NADH dehydrogenase subunit 1; Provisional
 14-98 4.07e-22

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177127  Cd Length: 324  Bit Score: 87.86  E-value: 4.07e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838  14 VLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFSLMISLFVW 93
Cdd:MTH00054   9 LAILVPLLISIAYLTLAERKVLGYIQCRKGPNVVGVYGLLQPLADGLKLFTKEIIIPNHANIFIYIMAPILSLTLAFIAW 88


                 ....*
gi 960498838  94 PIFPY 98
Cdd:MTH00054  89 GVIPY 93
NADHdh pfam00146
NADH dehydrogenase;
14-98 1.16e-21

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 85.99  E-value: 1.16e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   14 VLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFSLMISLFVW 93
Cdd:pfam00146   3 LLLLVPLLLAVAFLTWAERKVLARMQRRIGPNRVGPFGLLQPFADALKLLFKEDIIPAGADKFLFLLAPIIAFIPALLAF 82


                  ....*
gi 960498838   94 PIFPY 98
Cdd:pfam00146  83 AVIPF 87
NuoH COG1005
NADH:ubiquinone oxidoreductase subunit 1 (chain H) [Energy production and conversion]; NADH: ...
 5-98 1.74e-20

NADH:ubiquinone oxidoreductase subunit 1 (chain H) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 1 (chain H) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440629  Cd Length: 329  Bit Score: 83.26  E-value: 1.74e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   5 DLFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVF 84
Cdd:COG1005    7 PLLITLIKALVILVFLLLLAAYLTWAERKVLARMQDRIGPNRVGPFGLLQPLADGLKLLFKEDIIPAGADKFLFLLAPIL 86

                         90
                 ....*....|....
gi 960498838  85 SLMISLFVWPIFPY 98
Cdd:COG1005   87 AFIPALLAFAVIPF 100
PRK06076 PRK06076
NADH-quinone oxidoreductase subunit NuoH;
6-98 1.53e-17

NADH-quinone oxidoreductase subunit NuoH;


Pssm-ID: 235692  Cd Length: 322  Bit Score: 75.23  E-value: 1.53e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   6 LFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFS 85
Cdd:PRK06076   9 LLLILLKAVVILVVVLLCVAFLIWFERKVLARMQLRYGPNRVGPFGLLQLVADGIKLLFKEDIIPAGADKVLFLLAPVIA 88

                         90
                 ....*....|...
gi 960498838  86 LMISLFVWPIFPY 98
Cdd:PRK06076  89 FIPAFLAWAVIPF 101
ND1 MTH00090
NADH dehydrogenase subunit 1; Provisional
 12-99 2.65e-17

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177153  Cd Length: 284  Bit Score: 74.16  E-value: 2.65e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838  12 NFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYFSPVFSLMISLF 91
Cdd:MTH00090   1 MLLLMMIFILQAIAFITLYERHLLGSSQNRLGPNKVSFMGVLQALLDGVKLLKKEQMLPLNSSDLSFLLVPGVSFVVMYL 80


                 ....*...
gi 960498838  92 VWPIFPYL 99
Cdd:MTH00090  81 EWFVLPYF 88
ND1 MTH00029
NADH dehydrogenase subunit 1; Provisional
 1-95 3.90e-17

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177108  Cd Length: 343  Bit Score: 74.67  E-value: 3.90e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498838   1 MMLYDLFMFSLNFVLLIICVLISVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICKEQPIPIMSNYLLYYF 80
Cdd:MTH00029   1 MTIYSYITVTIKLLIIFVPLLLSVAYLTLAERKVLGLMQNRKGPAIVGPWGLVQPIADGVKLLTKELIIPSQANKFLYYI 80

                         90
                 ....*....|....*
gi 960498838  81 SPVFSLMISLFVWPI 95
Cdd:MTH00029  81 APIISFTLAILAWAI 95
ND1 MTH00058
NADH dehydrogenase subunit 1; Provisional
 7-65 7.74e-12

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177130  Cd Length: 293  Bit Score: 59.55  E-value: 7.74e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 960498838   7 FMFSLNFVLLIICVLIsVAFLTLLERKVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICK 65
Cdd:MTH00058   2 FGLVSGLEGLLIILLL-VAFFILGERKILGYIQLRKGPNKVGIVGLLQSFADLLKLVVK 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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