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Conserved domains on  [gi|960498858|gb|ALR85551|]
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NADH dehydrogenase subunit I, partial (mitochondrion) [Leatettix moraki]

Protein Classification

complex I subunit 1 family protein( domain architecture ID 103)

complex I subunit 1 family protein similar to NADH dehydrogenase subunit 1, which is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

EC:  7.1.1.-
Gene Ontology:  GO:0016655|GO:0016020
PubMed:  23417064|24059520
SCOP:  4005664

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06076 super family cl00469
NADH-quinone oxidoreductase subunit NuoH;
6-104 1.62e-38

NADH-quinone oxidoreductase subunit NuoH;


The actual alignment was detected with superfamily member MTH00193:

Pssm-ID: 469782  Cd Length: 306  Bit Score: 130.27  E-value: 1.62e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   6 FFMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFS 85
Cdd:MTH00193   1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                         90
                 ....*....|....*....
gi 960498858  86 LMISLFIWIIFPYLTYFCS 104
Cdd:MTH00193  81 LFLSLLIWLIYPYLFNLIS 99
 
Name Accession Description Interval E-value
ND1 MTH00193
NADH dehydrogenase subunit 1; Provisional
 6-104 1.62e-38

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177241  Cd Length: 306  Bit Score: 130.27  E-value: 1.62e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   6 FFMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFS 85
Cdd:MTH00193   1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                         90
                 ....*....|....*....
gi 960498858  86 LMISLFIWIIFPYLTYFCS 104
Cdd:MTH00193  81 LFLSLLIWLIYPYLFNLIS 99
NADHdh pfam00146
NADH dehydrogenase;
14-98 5.27e-17

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 73.66  E-value: 5.27e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   14 VFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSLMISLFIW 93
Cdd:pfam00146   3 LLLLVPLLLAVAFLTWAERKVLARMQRRIGPNRVGPFGLLQPFADALKLLFKEDIIPAGADKFLFLLAPIIAFIPALLAF 82


                  ....*
gi 960498858   94 IIFPY 98
Cdd:pfam00146  83 AVIPF 87
 
Name Accession Description Interval E-value
ND1 MTH00193
NADH dehydrogenase subunit 1; Provisional
 6-104 1.62e-38

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177241  Cd Length: 306  Bit Score: 130.27  E-value: 1.62e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   6 FFMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFS 85
Cdd:MTH00193   1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                         90
                 ....*....|....*....
gi 960498858  86 LMISLFIWIIFPYLTYFCS 104
Cdd:MTH00193  81 LFLSLLIWLIYPYLFNLIS 99
ND1 MTH00225
NADH dehydrogenase subunit 1; Provisional
 8-102 2.03e-31

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214465  Cd Length: 305  Bit Score: 112.05  E-value: 2.03e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   8 MFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSLM 87
Cdd:MTH00225   2 SFLLKFLIMLICLLLSVAFYTLLERKVLGYIQLRKGPNKVGLMGLPQPFADALKLFTKEQTKPQLSNKLPYYIAPILSLI 81

                         90
                 ....*....|....*
gi 960498858  88 ISLFIWIIFPYLTYF 102
Cdd:MTH00225  82 LSLILWSLYPSMFSI 96
ND1 MTH00143
NADH dehydrogenase subunit 1; Provisional
 7-104 1.73e-29

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177201  Cd Length: 307  Bit Score: 106.88  E-value: 1.73e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   7 FMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSL 86
Cdd:MTH00143   1 LVSLLSSVFTYLCVLLAVAFFTLLERKGLGYFQIRKGPNKVGLMGLPQPLADAVKLFTKEFVKPTMSNKFPFFLAPCLSL 80

                         90
                 ....*....|....*...
gi 960498858  87 MISLFIWIIFPYltYFCS 104
Cdd:MTH00143  81 ILALLLWQLYPS--YFSS 96
ND1 MTH00218
NADH dehydrogenase subunit 1; Provisional
 10-97 4.92e-24

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214463  Cd Length: 311  Bit Score: 92.67  E-value: 4.92e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858  10 IINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSLMIS 89
Cdd:MTH00218   5 LINLLLYILPVLLAVAFLTLLERKVLGYMQLRKGPNVVGPYGLLQPIADGVKLFIKEPIRPSTSSPFLFLLAPILALTLA 84


                 ....*...
gi 960498858  90 LFIWIIFP 97
Cdd:MTH00218  85 LLLWMPLP 92
ND1 MTH00104
NADH dehydrogenase subunit 1; Provisional
 8-97 1.40e-23

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177166  Cd Length: 318  Bit Score: 91.61  E-value: 1.40e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   8 MFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSLM 87
Cdd:MTH00104   1 MFMINILLLIIPILLAVAFLTLVERKVLGYMQLRKGPNIVGPYGLLQPFADAMKLFTKEPLRPLTSSTTMFIIAPILALT 80

                         90
                 ....*....|
gi 960498858  88 ISLFIWIIFP 97
Cdd:MTH00104  81 LALTMWIPLP 90
ND1 MTH00111
NADH dehydrogenase subunit 1; Provisional
 7-97 3.42e-23

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214422  Cd Length: 323  Bit Score: 90.73  E-value: 3.42e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   7 FMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSL 86
Cdd:MTH00111   5 LLNLINPLLYIIPILIAVAFLTLLERKILGYMQLRKGPNIVGPFGLLQPIADGVKLFIKEPIRPSTSSPILFTLTPILAL 84

                         90
                 ....*....|.
gi 960498858  87 MISLFIWIIFP 97
Cdd:MTH00111  85 LLALTIWTPLP 95
ND1 MTH00010
NADH dehydrogenase subunit 1; Validated
 9-98 6.90e-23

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 164586  Cd Length: 311  Bit Score: 89.45  E-value: 6.90e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   9 FIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSLMI 88
Cdd:MTH00010   5 FFISILLSYVMALLAMAFYTLLERKALGYFQLRKGPNKVGLAGIPQPFADAIKLFTKEQTKPSPANITPFLGAPMMSLIL 84

                         90
                 ....*....|
gi 960498858  89 SLFIWIIFPY 98
Cdd:MTH00010  85 ALLLWSLYPH 94
ND1 MTH00195
NADH dehydrogenase subunit 1; Provisional
 8-104 7.38e-23

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214452  Cd Length: 307  Bit Score: 89.42  E-value: 7.38e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   8 MFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSLM 87
Cdd:MTH00195   3 ISVIHFLIQIVPVLLAVAFFTLLERKILGYIQLRKGPNKVGPYGLLQPIADAVKLFIKEPVKPSTSSLWLFFFAPVLALA 82

                         90
                 ....*....|....*..
gi 960498858  88 ISLFIWIIFPYLTYFCS 104
Cdd:MTH00195  83 LALILWVPIPSPFGFSS 99
ND1 MTH00071
NADH dehydrogenase subunit 1; Provisional
 6-97 1.52e-22

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214418  Cd Length: 322  Bit Score: 88.91  E-value: 1.52e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   6 FFMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFS 85
Cdd:MTH00071   4 LISLIINPLLYIIPVLLAVAFLTLVERKVLGYMQLRKGPNIVGPMGLLQPIADGLKLFIKEPIRPSTSSQILFILMPTMA 83

                         90
                 ....*....|..
gi 960498858  86 LMISLFIWIIFP 97
Cdd:MTH00071  84 LTLALIIWTPLP 95
ND1 MTH00216
NADH dehydrogenase subunit 1; Provisional
 2-98 2.16e-22

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 164761  Cd Length: 327  Bit Score: 88.64  E-value: 2.16e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   2 MFYDFFMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFS 81
Cdd:MTH00216   1 MMVFIIFYLIKILIIIVPLLIAVAYLTLAERKVLGYMQARKGPNVVGVYGLLQPFADGVKLFTKEMVIPHHANLFVYIVA 80

                         90
                 ....*....|....*..
gi 960498858  82 PLFSLMISLFIWIIFPY 98
Cdd:MTH00216  81 PVLSFTLALIVWGVIPY 97
ND1 MTH00040
NADH dehydrogenase subunit 1; Validated
 7-97 3.67e-22

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 214409  Cd Length: 323  Bit Score: 87.72  E-value: 3.67e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   7 FMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSL 86
Cdd:MTH00040   4 ILFLINLLSFIVPVLLAVAFLTLVERKVLGYMQFRKGPNVVGPYGLLQPFADGLKLFIKETLKPSNASPYLFFFSPVLFL 83

                         90
                 ....*....|.
gi 960498858  87 MISLFIWIIFP 97
Cdd:MTH00040  84 FLALLLWSLIP 94
ND1 MTH00134
NADH dehydrogenase subunit 1; Provisional
 2-97 1.06e-21

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177192  Cd Length: 324  Bit Score: 86.58  E-value: 1.06e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   2 MFYDFFMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFS 81
Cdd:MTH00134   1 MLSTLITHIINPLAYIVPVLLAVAFLTLLERKVLGYMQLRKGPNIVGPYGLLQPIADGVKLFIKEPVRPSTSSPFLFLAT 80

                         90
                 ....*....|....*.
gi 960498858  82 PLFSLMISLFIWIIFP 97
Cdd:MTH00134  81 PMLALTLALTLWAPMP 96
ND1 MTH00054
NADH dehydrogenase subunit 1; Provisional
 8-98 3.15e-19

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177127  Cd Length: 324  Bit Score: 80.16  E-value: 3.15e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   8 MFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSLM 87
Cdd:MTH00054   3 IIIIKILAILVPLLISIAYLTLAERKVLGYIQCRKGPNVVGVYGLLQPLADGLKLFTKEIIIPNHANIFIYIMAPILSLT 82

                         90
                 ....*....|.
gi 960498858  88 ISLFIWIIFPY 98
Cdd:MTH00054  83 LAFIAWGVIPY 93
NADHdh pfam00146
NADH dehydrogenase;
14-98 5.27e-17

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 73.66  E-value: 5.27e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   14 VFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSLMISLFIW 93
Cdd:pfam00146   3 LLLLVPLLLAVAFLTWAERKVLARMQRRIGPNRVGPFGLLQPFADALKLLFKEDIIPAGADKFLFLLAPIIAFIPALLAF 82


                  ....*
gi 960498858   94 IIFPY 98
Cdd:pfam00146  83 AVIPF 87
PRK06076 PRK06076
NADH-quinone oxidoreductase subunit NuoH;
6-98 6.49e-15

NADH-quinone oxidoreductase subunit NuoH;


Pssm-ID: 235692  Cd Length: 322  Bit Score: 68.29  E-value: 6.49e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   6 FFMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFS 85
Cdd:PRK06076   9 LLLILLKAVVILVVVLLCVAFLIWFERKVLARMQLRYGPNRVGPFGLLQLVADGIKLLFKEDIIPAGADKVLFLLAPVIA 88

                         90
                 ....*....|...
gi 960498858  86 LMISLFIWIIFPY 98
Cdd:PRK06076  89 FIPAFLAWAVIPF 101
ND1 MTH00029
NADH dehydrogenase subunit 1; Provisional
 1-95 1.90e-14

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177108  Cd Length: 343  Bit Score: 66.96  E-value: 1.90e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858   1 MMFYDFFMFIINFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYF 80
Cdd:MTH00029   1 MTIYSYITVTIKLLIIFVPLLLSVAYLTLAERKVLGLMQNRKGPAIVGPWGLVQPIADGVKLLTKELIIPSQANKFLYYI 80

                         90
                 ....*....|....*
gi 960498858  81 SPLFSLMISLFIWII 95
Cdd:MTH00029  81 APIISFTLAILAWAI 95
ND1 MTH00090
NADH dehydrogenase subunit 1; Provisional
 12-104 2.67e-14

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177153  Cd Length: 284  Bit Score: 66.08  E-value: 2.67e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498858  12 NFVFLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLICSEQPMPILSNYLLYYFSPLFSLMISLF 91
Cdd:MTH00090   1 MLLLMMIFILQAIAFITLYERHLLGSSQNRLGPNKVSFMGVLQALLDGVKLLKKEQMLPLNSSDLSFLLVPGVSFVVMYL 80

                         90
                 ....*....|...
gi 960498858  92 IWIIFPYLTYFCS 104
Cdd:MTH00090  81 EWFVLPYFFDFLS 93
ND1 MTH00058
NADH dehydrogenase subunit 1; Provisional
 6-64 5.21e-11

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177130  Cd Length: 293  Bit Score: 57.24  E-value: 5.21e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 960498858   6 FFMFIINFVFLVICVLIsVAFLTLLERSVLGYIQIRKGPNKVGIMGIPQPFSDAIKLIC 64
Cdd:MTH00058   1 IFGLVSGLEGLLIILLL-VAFFILGERKILGYIQLRKGPNKVGIVGLLQSFADLLKLVV 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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