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Conserved domains on  [gi|961455216|gb|ALS31208|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Rubigula gularis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-280 3.76e-119

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 344.88  E-value: 3.76e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILTLAIAM 80
Cdd:MTH00112  25 HWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNPTSCTLLTLALAM 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  81 KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSI 160
Cdd:MTH00112 105 KLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQTQLRKIMAFSSI 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 161 SHLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKW 240
Cdd:MTH00112 185 AHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLTGFMPKW 264

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 961455216 241 LIIQELTKQDMTIAAIMISLLSLLSLFFYLRLAYCATITL 280
Cdd:MTH00112 265 LILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITL 304
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-280 3.76e-119

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 344.88  E-value: 3.76e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILTLAIAM 80
Cdd:MTH00112  25 HWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNPTSCTLLTLALAM 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  81 KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSI 160
Cdd:MTH00112 105 KLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQTQLRKIMAFSSI 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 161 SHLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKW 240
Cdd:MTH00112 185 AHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLTGFMPKW 264

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 961455216 241 LIIQELTKQDMTIAAIMISLLSLLSLFFYLRLAYCATITL 280
Cdd:MTH00112 265 LILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITL 304
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-244 1.33e-15

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 75.04  E-value: 1.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216    1 HWIMAWAGLEINTLAILPMI-SKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQL-----------THP 68
Cdd:pfam00361   3 DLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssGLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   69 ISCLILTLAIAMKLGL*PFHFWFPEVLQGSPL-MTGLLLSTMMKFPPI-----TLL************************ 142
Cdd:pfam00361  83 LLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYglirrSLLYLPSSPFIQQILLILAIISMLLGS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  143 ****NQTQIRKILAFSSISHLGWMAIII----TYNPKLTLLNFYLYVLMTTAVFLTLNSI-----KVLKLSVLMTTWTKI 213
Cdd:pfam00361 163 LAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSViyrrvHTRNIRDYGGLAKTM 242

                         250       260       270
                  ....*....|....*....|....*....|.
gi 961455216  214 PPLSAMLLLTLLSLAGLPPLTGFLPKWLIIQ 244
Cdd:pfam00361 243 PILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 1-198 2.41e-10

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 60.52  E-value: 2.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMIS-KSHHPRAI*AATKYFLTQATASALVLF-SSMTNAWhTGQWDITQL-----THPISCLI 73
Cdd:COG1007  123 DLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIaaalaAGGANSPL 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  74 LTLAIAM-------KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL**************************** 146
Cdd:COG1007  202 LLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPGLAADWQLLLAVLAVLSMT 281

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 961455216 147 -------NQTQIRKILAFSSISHLGWMAI-IITYNPK-LTLLNFYL--YVLMTTAVFLTLNSI 198
Cdd:COG1007  282 vgnlaalAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYLlaYLFMNLGAFAVILLL 344
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 27-273 1.88e-09

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 57.65  E-value: 1.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   27 RAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILT------------LAIAMKLGL*PFHFWFPEV 94
Cdd:TIGR01770 150 FSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDV 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   95 LQGSPLMTGLLLSTMMK---FPPITLL**************************----**NQTQIRKILAFSSISHLGWMA 167
Cdd:TIGR01770 230 YEGAPTPVTAFFSIVPKiaiFAVFLRLFLYILFGFSEAWQIFLAIIAFLSMLIgnfgALAQKKVKRLLAYSSISHVGYIL 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  168 IIITYNPKLTLLN--FYL--YVLMTTAVFLTLNSIKVLK------LSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFL 237
Cdd:TIGR01770 310 IGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKdewieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFF 389

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 961455216  238 PKWLIIQELTKQDMTIAAIMISLLSLLSLFFYLRLA 273
Cdd:TIGR01770 390 GKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-280 3.76e-119

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 344.88  E-value: 3.76e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILTLAIAM 80
Cdd:MTH00112  25 HWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNPTSCTLLTLALAM 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  81 KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSI 160
Cdd:MTH00112 105 KLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQTQLRKIMAFSSI 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 161 SHLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKW 240
Cdd:MTH00112 185 AHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLTGFMPKW 264

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 961455216 241 LIIQELTKQDMTIAAIMISLLSLLSLFFYLRLAYCATITL 280
Cdd:MTH00112 265 LILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITL 304
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-280 3.16e-99

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 294.40  E-value: 3.16e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILTLAIAM 80
Cdd:MTH00135  25 HWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSHPLPTTMITLALAL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  81 KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSI 160
Cdd:MTH00135 105 KIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTSTLVGGWGGL-NQTQLRKILAYSSI 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 161 SHLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKW 240
Cdd:MTH00135 184 AHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMPKW 263

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 961455216 241 LIIQELTKQDMTIAAIMISLLSLLSLFFYLRLAYCATITL 280
Cdd:MTH00135 264 LILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTI 303
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-280 2.41e-98

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 291.82  E-value: 2.41e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILTLAIAM 80
Cdd:MTH00070  25 HWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTGEWTIMNMQTPLPTIMLTIALMM 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  81 KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSI 160
Cdd:MTH00070 105 KLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLSTLIGGWGGLNQTQLRKIMAYSSI 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 161 SHLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKW 240
Cdd:MTH00070 185 AHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGGLPPTTGFIPKW 264

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 961455216 241 LIIQELTKQDMTIAAIMISLLSLLSLFFYLRLAYCATITL 280
Cdd:MTH00070 265 LILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTT 304
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-280 5.81e-86

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 260.55  E-value: 5.81e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILTLAIAM 80
Cdd:MTH00105  25 HWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTITKLTNPTASTLMTIALAM 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  81 KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSI 160
Cdd:MTH00105 105 KLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLNQTQLRKILAYSSI 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 161 SHLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKW 240
Cdd:MTH00105 185 AHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLGGLPPLTGFMPKW 264

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 961455216 241 LIIQELTKQDMTIAAIMISLLSLLSLFFYLRLAYCATITL 280
Cdd:MTH00105 265 MIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTM 304
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-280 1.89e-70

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 221.00  E-value: 1.89e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILTLAIAM 80
Cdd:MTH00200  25 HWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGISEMLGPLSETLILLALAL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  81 KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSI 160
Cdd:MTH00200 105 KLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSVLVGGWGGLNQTQLRKILAYSSI 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 161 SHLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKW 240
Cdd:MTH00200 185 AHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLGGLPPLTGFFPKW 264

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 961455216 241 LIIQELTKQDMTIAAIMISLLSLLSLFFYLRLAYCATITL 280
Cdd:MTH00200 265 LILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTL 304
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-280 5.19e-59

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 191.30  E-value: 5.19e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILTLAIAM 80
Cdd:MTH00041  25 HWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSSIIITLALAL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  81 KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSI 160
Cdd:MTH00041 105 KLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQTRKILAFSSI 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 161 SHLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKW 240
Cdd:MTH00041 185 AHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTGFLNKF 264

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 961455216 241 LIIQELTKQDMTIAAIMISLLSLLSLFFYLRLAYCATITL 280
Cdd:MTH00041 265 ISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTL 304
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 2-274 9.78e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 138.42  E-value: 9.78e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   2 WIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWhtgqwdITQLTHPISCLILTLAIAMK 81
Cdd:MTH00160  27 WFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML------NLMLFNNISSMLINSSLLLK 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  82 LGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSIS 161
Cdd:MTH00160 101 LGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIIILSAIIGAIGGL---NQTSLRKILAYSSIN 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 162 HLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKWL 241
Cdd:MTH00160 178 HLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFLPKWI 257

                        250       260       270
                 ....*....|....*....|....*....|...
gi 961455216 242 IIQELTKQDMTIAAIMISLLSLLSLFFYLRLAY 274
Cdd:MTH00160 258 IIQLLISNNMFFLLFILIMSSLITLYFYLRISY 290
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 2-272 3.94e-34

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 126.05  E-value: 3.94e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   2 WIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSmtnawhTGQWDITQLTHPISCLILTLAIAMK 81
Cdd:MTH00011  28 WLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSFPSLLKNITALMLLVSLMLK 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  82 LGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSIS 161
Cdd:MTH00011 102 LGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQLRPLLAYSSIG 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 162 HLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKWL 241
Cdd:MTH00011 182 HMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFTGFMPKLM 261

                        250       260       270
                 ....*....|....*....|....*....|.
gi 961455216 242 IIQELTKQDMTIAAIMISLLSLLSLFFYLRL 272
Cdd:MTH00011 262 AIETLTSNSMILILLVLIVGSLMNLFYYLNL 292
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-278 3.52e-33

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 123.46  E-value: 3.52e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITqlthpiscLILTLAIAM 80
Cdd:MTH00144  25 HWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM--------SLLLLGLCL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  81 KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL***********************-*****NQTQIRKILAFSS 159
Cdd:MTH00144  97 KLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVLSALVgSIGGLNQTQVRALLAYSS 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 160 ISHLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSiKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPK 239
Cdd:MTH00144 177 ISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWS-GDSGSMKDLGSLKPSYKTGLSIISLLLSLGGLPPFLGFCSK 255

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 961455216 240 WLIIQELTKQDMTIAAIMISLLSLLSLFFYLRLAYCATI 278
Cdd:MTH00144 256 LLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL 294
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 2-274 4.39e-27

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 107.07  E-value: 4.39e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   2 WIMAWAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTgqwditqLTHPISCLILTLAIAMK 81
Cdd:MTH00197  20 WFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL-------YLSLLSVVLVILGLLLK 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  82 LGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILAFSSIS 161
Cdd:MTH00197  93 LGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGM--NQSNIRQLLAYSSIG 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 162 HLGWMAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLKLSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFLPKWL 241
Cdd:MTH00197 171 HTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLSGFFLKWL 250

                        250       260       270
                 ....*....|....*....|....*....|...
gi 961455216 242 IIQELTKQDMTIAAIMISLLSLLSLFFYLRLAY 274
Cdd:MTH00197 251 ILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 2-272 9.45e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 76.22  E-value: 9.45e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   2 WIMAWAGLEINTLAILPMI-SKSHHPRAI*AATKYFLTQATASALVLFS-------------SMTNAWHTGQWDITQLTH 67
Cdd:MTH00196  15 WLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINLVLNSGQSFSSVSV 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  68 PISCLILTLAIAMKLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************N 147
Cdd:MTH00196  95 PIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSLFVGAIGAL--N 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 148 QTQIRKILAFSSISHLGWMAIIITYNP----KLTLLNFYLYVLMTTAVFLTLNSIKVLK--LSVLMTTWTKIPPLSAMLL 221
Cdd:MTH00196 173 QTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSGLSRRLPILAITLA 252

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 961455216 222 LTLLSLAGLPPLTGFLPKWLIIQELTKQDMTIAAIMISLLSLLSLFFYLRL 272
Cdd:MTH00196 253 LTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-244 1.33e-15

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 75.04  E-value: 1.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216    1 HWIMAWAGLEINTLAILPMI-SKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQL-----------THP 68
Cdd:pfam00361   3 DLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssGLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   69 ISCLILTLAIAMKLGL*PFHFWFPEVLQGSPL-MTGLLLSTMMKFPPI-----TLL************************ 142
Cdd:pfam00361  83 LLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYglirrSLLYLPSSPFIQQILLILAIISMLLGS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  143 ****NQTQIRKILAFSSISHLGWMAIII----TYNPKLTLLNFYLYVLMTTAVFLTLNSI-----KVLKLSVLMTTWTKI 213
Cdd:pfam00361 163 LAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSViyrrvHTRNIRDYGGLAKTM 242

                         250       260       270
                  ....*....|....*....|....*....|.
gi 961455216  214 PPLSAMLLLTLLSLAGLPPLTGFLPKWLIIQ 244
Cdd:pfam00361 243 PILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 2-243 5.31e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 62.34  E-value: 5.31e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   2 WIMAWAGLEINTLAILPMIS-KSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDI----TQLTHPISCLILTL 76
Cdd:MTH00199 119 WLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginSILTGDVGKILITI 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  77 AIAMKLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL****************************NQTQIRKILA 156
Cdd:MTH00199 199 SLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAIGAL--NQTKIKRLLA 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 157 FSSISHLGW----MAIIITYNPKLTLLNFYLYVLMTTAVFLTLNSIKVLK--LSVLMTTWTKIPPLSAMLLLTLLSLAGL 230
Cdd:MTH00199 277 YSGIGHMGFilfgVAIGSFESIQASLIYMIIYVIMSICSFSIILSLKLTKglIVEVSGLSRKNPVIALTLALTFLSIAGI 356

                        250
                 ....*....|...
gi 961455216 231 PPLTGFLPKWLII 243
Cdd:MTH00199 357 PPLAGFLSKWLIL 369
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 1-198 2.41e-10

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 60.52  E-value: 2.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMIS-KSHHPRAI*AATKYFLTQATASALVLF-SSMTNAWhTGQWDITQL-----THPISCLI 73
Cdd:COG1007  123 DLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIaaalaAGGANSPL 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  74 LTLAIAM-------KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL**************************** 146
Cdd:COG1007  202 LLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPGLAADWQLLLAVLAVLSMT 281

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 961455216 147 -------NQTQIRKILAFSSISHLGWMAI-IITYNPK-LTLLNFYL--YVLMTTAVFLTLNSI 198
Cdd:COG1007  282 vgnlaalAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYLlaYLFMNLGAFAVILLL 344
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 27-273 1.88e-09

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 57.65  E-value: 1.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   27 RAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPISCLILT------------LAIAMKLGL*PFHFWFPEV 94
Cdd:TIGR01770 150 FSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDV 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   95 LQGSPLMTGLLLSTMMK---FPPITLL**************************----**NQTQIRKILAFSSISHLGWMA 167
Cdd:TIGR01770 230 YEGAPTPVTAFFSIVPKiaiFAVFLRLFLYILFGFSEAWQIFLAIIAFLSMLIgnfgALAQKKVKRLLAYSSISHVGYIL 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  168 IIITYNPKLTLLN--FYL--YVLMTTAVFLTLNSIKVLK------LSVLMTTWTKIPPLSAMLLLTLLSLAGLPPLTGFL 237
Cdd:TIGR01770 310 IGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKdewieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFF 389

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 961455216  238 PKWLIIQELTKQDMTIAAIMISLLSLLSLFFYLRLA 273
Cdd:TIGR01770 390 GKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 1-186 8.48e-08

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 52.94  E-value: 8.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLAILPMISKSHHPRAI*AAT---------KYFLTQATASALVLFSSMTNAWHTGQ------------ 59
Cdd:MTH00198 209 NWLTIYLALEFQTLALFILAGEGSQPGSHFPSPgntppesglKYWILGAMSSGFYLFGCALYFGFTGNegmlgtilsatl 288

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  60 --WDITQLTHPISCLILTLAIAMKLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL******************* 137
Cdd:MTH00198 289 etTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITSKLLLSVAIIS 366

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 961455216 138 *********NQTQIRKILAFSSISHLGWMAIIITYNPKLTLLNFYLYVL 186
Cdd:MTH00198 367 LVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAV 415
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 6-258 7.86e-06

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 46.68  E-value: 7.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   6 WAGLEINTLAILPMISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQLTHPIS----------CLILT 75
Cdd:COG0651  133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAeldpglllaaFALLL 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  76 LAIAMKLGL*PFHFWFPEVLQGSP-----LMTGLLLST----MMKFPpITLL**************************** 146
Cdd:COG0651  213 VGFGIKAALFPLHFWLPDAYPAAPspvsaLLSGLLTKVgvyaILRVL-TLLFGADPALFLGTLLLVLGLLTMLVGALGAL 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 147 NQTQIRKILAFSSISHLGWMAIIITYNPKLTLLNFYLYV----LMTTAVFLTLNSIKVL----KLSVLMTTWTKIPPLSA 218
Cdd:COG0651  292 AQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFLAAGAIERAtgtrDLDKLGGLGKRMPLTAA 371

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 961455216 219 MLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMTIAAIMI 258
Cdd:COG0651  372 AFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVL 411
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
1-192 9.32e-06

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 46.35  E-value: 9.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216   1 HWIMAWAGLEINTLA--ILPMISKsHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQWDITQL-----THPISCLI 73
Cdd:PRK05777 124 DLLTLFLGLELLSLPlyALAALRR-DRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIakalaDGSGNSLL 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  74 LTLAIAM-------KLGL*PFHFWFPEVLQGSPLMTGLLLSTMMKFPPITLL**************************** 146
Cdd:PRK05777 203 LLFGLVFllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLLVVAFGGLSEDWQQVLAIIAIASML 282

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 961455216 147 -------NQTQIRKILAFSSISHLGWM--AIIITYNPKLTLLNFYL--YVLMTTAVF 192
Cdd:PRK05777 283 vgnlaalSQTNIKRLLAYSSIAHAGYLlvGLAAGTAEGYSAVLFYLlaYLFMTLGAF 339
ndhB CHL00049
NADH dehydrogenase subunit 2
 31-185 1.15e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 39.99  E-value: 1.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  31 AATKYFLTQATASALVL--FSSM--TNAWHTGQWDI------TQLTHPISCLI----LTLAIAMKLGL*PFHFWFPEVLQ 96
Cdd:CHL00049 163 ATMKYLLMGGASSSILVygFSWLygLSGGEIELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYE 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  97 GSPL-----------MTGLLLSTMMkfppITLL****************************NQTQIRKILAFSSISHLGW 165
Cdd:CHL00049 243 GSPTpvvaflsvtskVAASALATRI----FDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180
                 ....*....|....*....|....*..
gi 961455216 166 MAI-IITYNPK------LTLLNFYLYV 185
Cdd:CHL00049 319 VIIgIIVGDSNdgyasmITYMLFYIFM 345
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
26-99 3.87e-03

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 38.49  E-value: 3.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  26 PRAI*AATKYFLTQATASALVLF-SSMTNAWHTGQWDITQLTHPIS---------CLILTLA-IAMKLGL*PFHFWFPEV 94
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSAIALALItspslglalALVFVIAgIAFKISAVPFHQWTPDV 236


                 ....*
gi 961455216  95 LQGSP 99
Cdd:PRK02504 237 YEGSP 241
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 14-106 6.24e-03

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 37.75  E-value: 6.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216  14 LAILPM---ISKSHHPRAI*AATKYFLTQATASALVLFSSMTNAWHTGQW--DITQLT-HPIS-------CLILTLAIAM 80
Cdd:COG1008  142 LMLIPMyflIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAaAPLPltaqlllFLAFFIAFAV 221

                         90       100       110
                 ....*....|....*....|....*....|.
gi 961455216  81 KLGL*PFHFWFPEVLQ-----GSPLMTGLLL 106
Cdd:COG1008  222 KVPMFPFHTWLPDAHVeaptaGSVLLAGVLL 252
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 151-258 8.02e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 37.41  E-value: 8.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961455216 151 IRKILAFSSISHLGWMAIIITYNPKLTLLNFYLYV----LMTTAVFLTLNSIK----VLKLSVLMTTWTKIPPLSAMLLL 222
Cdd:PRK12662 303 IKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIvnhsIVKSALFMVSGSISyhfgTTKLEDCLNLWKSMPKITLAFVL 382

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 961455216 223 TLLSLAGLPPLTGFLPKWLIIQELTKQDMTIAAIMI 258
Cdd:PRK12662 383 LSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVL 418
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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