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Conserved domains on  [gi|1272516183|gb|ATP60634|]
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LasR [Cloning vector pCRB_DRT7VTPLux*50]

Protein Classification

LuxR family transcriptional regulator( domain architecture ID 11143035)

LuxR family transcriptional regulator similar to Pseudomonas aeruginosa LasR and Vibrio fischeri LuxR, which are transcriptional activators of the elastase structural gene (LasB) and bioluminescence operon, respectively

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Autoind_bind pfam03472
Autoinducer binding domain; This domain is found a a large family of transcriptional ...
 18-161 2.78e-38

Autoinducer binding domain; This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules (N-Acyl homoserine lactones, chlorolactone and rosmarinic acid) (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


:

Pssm-ID: 427319  Cd Length: 148  Bit Score: 130.56  E-value: 2.78e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183  18 EWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQT-- 95
Cdd:pfam03472   4 ELFDALARLAAALGFDHFAYGARAPLGLSAPDVLVLSNYPAEWLDRYDEANYFAIDPVVRHARRSSSPFSWSDVLFAEar 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1272516183  96 RKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFIEsvLPTLWMLKDYALQS 161
Cdd:pfam03472  84 GAERRFLDEARDFGLRDGYTVPVHGPGGRLGALSFAGPGEDLDPAEAIEA--AARLQLLAIYAHLR 147
GerE pfam00196
Bacterial regulatory proteins, luxR family;
175-231 4.00e-23

Bacterial regulatory proteins, luxR family;


:

Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 88.41  E-value: 4.00e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1272516183 175 VVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMA 231
Cdd:pfam00196   1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
 
Name Accession Description Interval E-value
Autoind_bind pfam03472
Autoinducer binding domain; This domain is found a a large family of transcriptional ...
 18-161 2.78e-38

Autoinducer binding domain; This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules (N-Acyl homoserine lactones, chlorolactone and rosmarinic acid) (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 427319  Cd Length: 148  Bit Score: 130.56  E-value: 2.78e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183  18 EWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQT-- 95
Cdd:pfam03472   4 ELFDALARLAAALGFDHFAYGARAPLGLSAPDVLVLSNYPAEWLDRYDEANYFAIDPVVRHARRSSSPFSWSDVLFAEar 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1272516183  96 RKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFIEsvLPTLWMLKDYALQS 161
Cdd:pfam03472  84 GAERRFLDEARDFGLRDGYTVPVHGPGGRLGALSFAGPGEDLDPAEAIEA--AARLQLLAIYAHLR 147
GerE pfam00196
Bacterial regulatory proteins, luxR family;
175-231 4.00e-23

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 88.41  E-value: 4.00e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1272516183 175 VVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMA 231
Cdd:pfam00196   1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
PRK10188 PRK10188
transcriptional regulator SdiA;
55-237 5.27e-21

transcriptional regulator SdiA;


Pssm-ID: 182292 [Multi-domain]  Cd Length: 240  Bit Score: 87.92  E-value: 5.27e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183  55 NYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYqtRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSveA 134
Cdd:PRK10188   62 TYPEAWVSHYQAENYFAIDPVLKPENFSQGHLMWNDDLF--SEAQALWDAARAHGLRRGVTQCLMLPNRALGFLSFS--R 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183 135 ENRAEANRFIESVLPTLWMLKDYALQsgAGLAFEHPVSKP--VVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHM 212
Cdd:PRK10188  138 CSAREIPILSDELELRLQLLVRESLM--ALMRLEDEMVMTpeMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQ 215

                         170       180
                  ....*....|....*....|....*
gi 1272516183 213 GNIRRKFGVTSRRVAAIMAVNLGLI 237
Cdd:PRK10188  216 KNMQKKFNAPNKTQIACYAAATGLI 240
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
50-237 3.50e-20

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 84.81  E-value: 3.50e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183  50 AFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALS 129
Cdd:COG2771     1 LLLLALALLLLALLLLLLALLALLLLLLLAALLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183 130 LSVEAENRAEANRFIESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVN 209
Cdd:COG2771    81 LLALLLLLALLALLAALLARLAALLLALALAALLLAALARLLARAPGLTPREREVLRLLAEGLTLKEIARILGISERTVR 160

                         170       180
                  ....*....|....*....|....*...
gi 1272516183 210 FHMGNIRRKFGVTSRRVAAIMAVNLGLI 237
Cdd:COG2771   161 THLKRIYRKLGVSSRAELVALALRLGLI 188
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 177-233 2.64e-19

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 78.35  E-value: 2.64e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1272516183 177 LTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVN 233
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYAIR 57
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 174-231 4.81e-19

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 77.95  E-value: 4.81e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1272516183  174 PVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMA 231
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 133-237 2.93e-16

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 72.62  E-value: 2.93e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183 133 EAENRAEANRFIESVLPTLWMLkDYALQSGAGLAFEHpvskpVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHM 212
Cdd:COG2197    32 EAADGEEALELLEELRPDVVLL-DIRMPGMDGLEALR-----RLLTPREREVLRLLAEGLSNKEIAERLGISERTVKTHV 105

                          90       100
                  ....*....|....*....|....*
gi 1272516183 213 GNIRRKFGVTSRRVAAIMAVNLGLI 237
Cdd:COG2197   106 SNILRKLGVRNRTELVLLALRLGLL 130
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
176-230 1.74e-05

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 44.46  E-value: 1.74e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1272516183 176 VLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIM 230
Cdd:PRK10403  153 VLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATIL 207
 
Name Accession Description Interval E-value
Autoind_bind pfam03472
Autoinducer binding domain; This domain is found a a large family of transcriptional ...
 18-161 2.78e-38

Autoinducer binding domain; This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules (N-Acyl homoserine lactones, chlorolactone and rosmarinic acid) (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 427319  Cd Length: 148  Bit Score: 130.56  E-value: 2.78e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183  18 EWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQT-- 95
Cdd:pfam03472   4 ELFDALARLAAALGFDHFAYGARAPLGLSAPDVLVLSNYPAEWLDRYDEANYFAIDPVVRHARRSSSPFSWSDVLFAEar 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1272516183  96 RKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFIEsvLPTLWMLKDYALQS 161
Cdd:pfam03472  84 GAERRFLDEARDFGLRDGYTVPVHGPGGRLGALSFAGPGEDLDPAEAIEA--AARLQLLAIYAHLR 147
GerE pfam00196
Bacterial regulatory proteins, luxR family;
175-231 4.00e-23

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 88.41  E-value: 4.00e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1272516183 175 VVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMA 231
Cdd:pfam00196   1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
PRK10188 PRK10188
transcriptional regulator SdiA;
55-237 5.27e-21

transcriptional regulator SdiA;


Pssm-ID: 182292 [Multi-domain]  Cd Length: 240  Bit Score: 87.92  E-value: 5.27e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183  55 NYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYqtRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSveA 134
Cdd:PRK10188   62 TYPEAWVSHYQAENYFAIDPVLKPENFSQGHLMWNDDLF--SEAQALWDAARAHGLRRGVTQCLMLPNRALGFLSFS--R 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183 135 ENRAEANRFIESVLPTLWMLKDYALQsgAGLAFEHPVSKP--VVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHM 212
Cdd:PRK10188  138 CSAREIPILSDELELRLQLLVRESLM--ALMRLEDEMVMTpeMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQ 215

                         170       180
                  ....*....|....*....|....*
gi 1272516183 213 GNIRRKFGVTSRRVAAIMAVNLGLI 237
Cdd:PRK10188  216 KNMQKKFNAPNKTQIACYAAATGLI 240
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
50-237 3.50e-20

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 84.81  E-value: 3.50e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183  50 AFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALS 129
Cdd:COG2771     1 LLLLALALLLLALLLLLLALLALLLLLLLAALLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183 130 LSVEAENRAEANRFIESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVN 209
Cdd:COG2771    81 LLALLLLLALLALLAALLARLAALLLALALAALLLAALARLLARAPGLTPREREVLRLLAEGLTLKEIARILGISERTVR 160

                         170       180
                  ....*....|....*....|....*...
gi 1272516183 210 FHMGNIRRKFGVTSRRVAAIMAVNLGLI 237
Cdd:COG2771   161 THLKRIYRKLGVSSRAELVALALRLGLI 188
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 177-233 2.64e-19

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 78.35  E-value: 2.64e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1272516183 177 LTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVN 233
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYAIR 57
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 174-231 4.81e-19

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 77.95  E-value: 4.81e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1272516183  174 PVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMA 231
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 133-237 2.93e-16

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 72.62  E-value: 2.93e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183 133 EAENRAEANRFIESVLPTLWMLkDYALQSGAGLAFEHpvskpVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHM 212
Cdd:COG2197    32 EAADGEEALELLEELRPDVVLL-DIRMPGMDGLEALR-----RLLTPREREVLRLLAEGLSNKEIAERLGISERTVKTHV 105

                          90       100
                  ....*....|....*....|....*
gi 1272516183 213 GNIRRKFGVTSRRVAAIMAVNLGLI 237
Cdd:COG2197   106 SNILRKLGVRNRTELVLLALRLGLL 130
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 171-239 1.51e-14

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 66.52  E-value: 1.51e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1272516183 171 VSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL 239
Cdd:COG5905     7 TSHPSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWALRLGLLSL 75
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
176-230 1.74e-05

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 44.46  E-value: 1.74e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1272516183 176 VLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIM 230
Cdd:PRK10403  153 VLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATIL 207
PRK13870 PRK13870
transcriptional regulator TraR; Provisional
 53-237 9.68e-05

transcriptional regulator TraR; Provisional


Pssm-ID: 172390 [Multi-domain]  Cd Length: 234  Bit Score: 42.29  E-value: 9.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183  53 VGNYPAAWREHYDRAGYARVDPTVSHcTQSVLPIF-WE-----PSiyQTRKQHEFFEEASAAGLVYGLTMPLHGARGELG 126
Cdd:PRK13870   50 VTNYHREWQSVYFDKKFDALDPVVKR-ARSRKHIFtWSgeqerPR--LSKDERAFYAHAADFGIRSGITIPIKTANGSMS 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1272516183 127 ALSLSVEaENRAEANRFIESVLPTLWMLKDYALQSGagLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEA 206
Cdd:PRK13870  127 MFTLASE-KPVIDLDREIDAVAAAATIGQIHARISF--LRTTPTAEDAAWLDPKEATYLRWIAVGKTMEEIADVEGVKYN 203

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1272516183 207 NVNFHMGNIRRKFGVTSRRVAAIMAVNLGLI 237
Cdd:PRK13870  204 SVRVKLREAMKRFDVRSKAHLTALAIRRKLI 234
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
189-237 2.44e-04

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 40.84  E-value: 2.44e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1272516183 189 AIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLI 237
Cdd:COG2909   135 AEGLSNKEIAERLFISVNTVKTHLRNIYRKLGVRSRTEAVARARELGLL 183
PRK10100 PRK10100
transcriptional regulator CsgD;
154-227 3.99e-03

transcriptional regulator CsgD;


Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 37.54  E-value: 3.99e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1272516183 154 LKDYALQSGAGLAFEHPVSKPvvLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVA 227
Cdd:PRK10100  135 LASYLITHSGNYRYNSTESAL--LTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQA 206
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 177-223 4.19e-03

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 37.00  E-value: 4.19e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1272516183 177 LTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTS 223
Cdd:COG4566   138 LTPREREVLDLVVAGLSNKQIARELGISPRTVEVHRANVMEKLGARS 184
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 177-233 4.94e-03

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 36.93  E-value: 4.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1272516183 177 LTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVN 233
Cdd:PRK10651  156 LTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQ 212
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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