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Conserved domains on  [gi|1273811408|gb|ATQ39737|]
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NADH dehydrogenase subunit I, partial (mitochondrion) [Betiscoides sp. B111_li_38]

Protein Classification

complex I subunit 1 family protein( domain architecture ID 103)

complex I subunit 1 family protein similar to NADH dehydrogenase subunit 1, which is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

EC:  7.1.1.-
Gene Ontology:  GO:0016655|GO:0016020
PubMed:  23417064|24059520
SCOP:  4005664

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK06076 super family cl00469
NADH-quinone oxidoreductase subunit NuoH;
6-111 2.64e-42

NADH-quinone oxidoreductase subunit NuoH;


The actual alignment was detected with superfamily member MTH00193:

Pssm-ID: 469782  Cd Length: 306  Bit Score: 140.29  E-value: 2.64e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   6 LLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFS 85
Cdd:MTH00193    1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                          90       100
                  ....*....|....*....|....*.
gi 1273811408  86 LMISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00193   81 LFLSLLIWLIYPYLFNLISFNLGILF 106
 
Name Accession Description Interval E-value
ND1 MTH00193
NADH dehydrogenase subunit 1; Provisional
 6-111 2.64e-42

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177241  Cd Length: 306  Bit Score: 140.29  E-value: 2.64e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   6 LLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFS 85
Cdd:MTH00193    1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                          90       100
                  ....*....|....*....|....*.
gi 1273811408  86 LMISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00193   81 LFLSLLIWLIYPYLFNLISFNLGILF 106
NADHdh pfam00146
NADH dehydrogenase;
14-98 6.14e-18

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 76.36  E-value: 6.14e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408  14 ILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFSLMISLFVW 93
Cdd:pfam00146   3 LLLLVPLLLAVAFLTWAERKVLARMQRRIGPNRVGPFGLLQPFADALKLLFKEDIIPAGADKFLFLLAPIIAFIPALLAF 82


                  ....*
gi 1273811408  94 SIFPY 98
Cdd:pfam00146  83 AVIPF 87
 
Name Accession Description Interval E-value
ND1 MTH00193
NADH dehydrogenase subunit 1; Provisional
 6-111 2.64e-42

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177241  Cd Length: 306  Bit Score: 140.29  E-value: 2.64e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   6 LLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFS 85
Cdd:MTH00193    1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                          90       100
                  ....*....|....*....|....*.
gi 1273811408  86 LMISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00193   81 LFLSLLIWLIYPYLFNLISFNLGILF 106
ND1 MTH00225
NADH dehydrogenase subunit 1; Provisional
 7-111 8.28e-34

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214465  Cd Length: 305  Bit Score: 118.60  E-value: 8.28e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   7 LMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFSL 86
Cdd:MTH00225    1 MSFLLKFLIMLICLLLSVAFYTLLERKVLGYIQLRKGPNKVGLMGLPQPFADALKLFTKEQTKPQLSNKLPYYIAPILSL 80

                          90       100
                  ....*....|....*....|....*
gi 1273811408  87 MISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00225   81 ILSLILWSLYPSMFSIYSFKFGILF 105
ND1 MTH00143
NADH dehydrogenase subunit 1; Provisional
 7-111 2.09e-30

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177201  Cd Length: 307  Bit Score: 109.57  E-value: 2.09e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   7 LMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFSL 86
Cdd:MTH00143    1 LVSLLSSVFTYLCVLLAVAFFTLLERKGLGYFQIRKGPNKVGLMGLPQPLADAVKLFTKEFVKPTMSNKFPFFLAPCLSL 80

                          90       100
                  ....*....|....*....|....*
gi 1273811408  87 MISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00143   81 ILALLLWQLYPSYFSSSYFGWGLLF 105
ND1 MTH00195
NADH dehydrogenase subunit 1; Provisional
 6-111 5.02e-25

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214452  Cd Length: 307  Bit Score: 95.58  E-value: 5.02e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   6 LLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFS 85
Cdd:MTH00195    1 WMISVIHFLIQIVPVLLAVAFFTLLERKILGYIQLRKGPNKVGPYGLLQPIADAVKLFIKEPVKPSTSSLWLFFFAPVLA 80

                          90       100
                  ....*....|....*....|....*.
gi 1273811408  86 LMISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00195   81 LALALILWVPIPSPFGFSSINLSVLF 106
ND1 MTH00111
NADH dehydrogenase subunit 1; Provisional
 6-111 4.60e-24

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214422  Cd Length: 323  Bit Score: 93.04  E-value: 4.60e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   6 LLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFS 85
Cdd:MTH00111    4 LLLNLINPLLYIIPILIAVAFLTLLERKILGYMQLRKGPNIVGPFGLLQPIADGVKLFIKEPIRPSTSSPILFTLTPILA 83

                          90       100
                  ....*....|....*....|....*.
gi 1273811408  86 LMISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00111   84 LLLALTIWTPLPMPFPLADLNLGLLF 109
ND1 MTH00104
NADH dehydrogenase subunit 1; Provisional
 8-111 5.21e-23

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177166  Cd Length: 318  Bit Score: 90.45  E-value: 5.21e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   8 MFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFSLM 87
Cdd:MTH00104    1 MFMINILLLIIPILLAVAFLTLVERKVLGYMQLRKGPNIVGPYGLLQPFADAMKLFTKEPLRPLTSSTTMFIIAPILALT 80

                          90       100
                  ....*....|....*....|....
gi 1273811408  88 ISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00104   81 LALTMWIPLPMPYPLINMNLGVLF 104
ND1 MTH00071
NADH dehydrogenase subunit 1; Provisional
 6-111 7.50e-23

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214418  Cd Length: 322  Bit Score: 90.06  E-value: 7.50e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   6 LLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFS 85
Cdd:MTH00071    4 LISLIINPLLYIIPVLLAVAFLTLVERKVLGYMQLRKGPNIVGPMGLLQPIADGLKLFIKEPIRPSTSSQILFILMPTMA 83

                          90       100
                  ....*....|....*....|....*.
gi 1273811408  86 LMISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00071   84 LTLALIIWTPLPMPNNLSNLNLGILF 109
ND1 MTH00134
NADH dehydrogenase subunit 1; Provisional
 2-111 1.51e-22

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177192  Cd Length: 324  Bit Score: 89.28  E-value: 1.51e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   2 MLYDLLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFS 81
Cdd:MTH00134    1 MLSTLITHIINPLAYIVPVLLAVAFLTLLERKVLGYMQLRKGPNIVGPYGLLQPIADGVKLFIKEPVRPSTSSPFLFLAT 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 1273811408  82 PIFSLMISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00134   81 PMLALTLALTLWAPMPMPYPVTDLNLGILF 110
ND1 MTH00216
NADH dehydrogenase subunit 1; Provisional
 2-98 2.95e-22

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 164761  Cd Length: 327  Bit Score: 88.64  E-value: 2.95e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   2 MLYDLLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFS 81
Cdd:MTH00216    1 MMVFIIFYLIKILIIIVPLLIAVAYLTLAERKVLGYMQARKGPNVVGVYGLLQPFADGVKLFTKEMVIPHHANLFVYIVA 80

                          90
                  ....*....|....*..
gi 1273811408  82 PIFSLMISLFVWSIFPY 98
Cdd:MTH00216   81 PVLSFTLALIVWGVIPY 97
ND1 MTH00218
NADH dehydrogenase subunit 1; Provisional
 6-111 5.18e-22

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214463  Cd Length: 311  Bit Score: 87.66  E-value: 5.18e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   6 LLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFS 85
Cdd:MTH00218    1 MLLSLINLLLYILPVLLAVAFLTLLERKVLGYMQLRKGPNVVGPYGLLQPIADGVKLFIKEPIRPSTSSPFLFLLAPILA 80

                          90       100
                  ....*....|....*....|....*.
gi 1273811408  86 LMISLFVWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00218   81 LTLALLLWMPLPLPFSLINLNLGVLF 106
ND1 MTH00010
NADH dehydrogenase subunit 1; Validated
 9-98 2.33e-21

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 164586  Cd Length: 311  Bit Score: 85.99  E-value: 2.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   9 FVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFSLMI 88
Cdd:MTH00010    5 FFISILLSYVMALLAMAFYTLLERKALGYFQLRKGPNKVGLAGIPQPFADAIKLFTKEQTKPSPANITPFLGAPMMSLIL 84

                          90
                  ....*....|
gi 1273811408  89 SLFVWSIFPY 98
Cdd:MTH00010   85 ALLLWSLYPH 94
ND1 MTH00040
NADH dehydrogenase subunit 1; Validated
 4-97 3.12e-21

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 214409  Cd Length: 323  Bit Score: 85.80  E-value: 3.12e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   4 YDLLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPI 83
Cdd:MTH00040    1 MSVILFLINLLSFIVPVLLAVAFLTLVERKVLGYMQFRKGPNVVGPYGLLQPFADGLKLFIKETLKPSNASPYLFFFSPV 80

                          90
                  ....*....|....
gi 1273811408  84 FSLMISLFVWSIFP 97
Cdd:MTH00040   81 LFLFLALLLWSLIP 94
ND1 MTH00054
NADH dehydrogenase subunit 1; Provisional
 6-98 6.54e-21

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177127  Cd Length: 324  Bit Score: 84.78  E-value: 6.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   6 LLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFS 85
Cdd:MTH00054    1 MGIIIIKILAILVPLLISIAYLTLAERKVLGYIQCRKGPNVVGVYGLLQPLADGLKLFTKEIIIPNHANIFIYIMAPILS 80

                          90
                  ....*....|...
gi 1273811408  86 LMISLFVWSIFPY 98
Cdd:MTH00054   81 LTLAFIAWGVIPY 93
NADHdh pfam00146
NADH dehydrogenase;
14-98 6.14e-18

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 76.36  E-value: 6.14e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408  14 ILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFSLMISLFVW 93
Cdd:pfam00146   3 LLLLVPLLLAVAFLTWAERKVLARMQRRIGPNRVGPFGLLQPFADALKLLFKEDIIPAGADKFLFLLAPIIAFIPALLAF 82


                  ....*
gi 1273811408  94 SIFPY 98
Cdd:pfam00146  83 AVIPF 87
ND1 MTH00090
NADH dehydrogenase subunit 1; Provisional
 12-111 1.54e-16

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177153  Cd Length: 284  Bit Score: 72.62  E-value: 1.54e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408  12 NFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYFSPIFSLMISLF 91
Cdd:MTH00090    1 MLLLMMIFILQAIAFITLYERHLLGSSQNRLGPNKVSFMGVLQALLDGVKLLKKEQMLPLNSSDLSFLLVPGVSFVVMYL 80

                          90       100
                  ....*....|....*....|
gi 1273811408  92 VWSIFPYLTYMCSFSYGFLF 111
Cdd:MTH00090   81 EWFVLPYFFDFLSFEYSLLF 100
ND1 MTH00029
NADH dehydrogenase subunit 1; Provisional
 1-95 5.98e-16

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177108  Cd Length: 343  Bit Score: 71.59  E-value: 5.98e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1273811408   1 MMLYDLLMFVMNFILLVICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLICSEQPIPIMSNYLLYYF 80
Cdd:MTH00029    1 MTIYSYITVTIKLLIIFVPLLLSVAYLTLAERKVLGLMQNRKGPAIVGPWGLVQPIADGVKLLTKELIIPSQANKFLYYI 80

                          90
                  ....*....|....*
gi 1273811408  81 SPIFSLMISLFVWSI 95
Cdd:MTH00029   81 APIISFTLAILAWAI 95
ND1 MTH00058
NADH dehydrogenase subunit 1; Provisional
 7-64 1.93e-08

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177130  Cd Length: 293  Bit Score: 50.31  E-value: 1.93e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1273811408   7 LMFVMNFILLVICVLIsVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAVKLIC 64
Cdd:MTH00058    2 FGLVSGLEGLLIILLL-VAFFILGERKILGYIQLRKGPNKVGIVGLLQSFADLLKLVV 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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