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Conserved domains on  [gi|1351314702|gb|AVI25211|]
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NADH dehydrogenase subunit 3 (mitochondrion) [Phyllomimus sp. YH-2018]

Protein Classification

NADH dehydrogenase subunit 3( domain architecture ID 10009596)

NADH dehydrogenase subunit 3 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 28-115 1.06e-26

NADH dehydrogenase subunit 3; Provisional


:

Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 95.23  E-value: 1.06e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  28 KTLNDHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYHE 107
Cdd:MTH00161   26 KSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFKTSNMMSWLITSSFFILILLLGLYYE 105


                  ....*...
gi 1351314702 108 WRQGALDW 115
Cdd:MTH00161  106 WNQGALEW 113
 
Name Accession Description Interval E-value
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 28-115 1.06e-26

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 95.23  E-value: 1.06e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  28 KTLNDHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYHE 107
Cdd:MTH00161   26 KSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFKTSNMMSWLITSSFFILILLLGLYYE 105


                  ....*...
gi 1351314702 108 WRQGALDW 115
Cdd:MTH00161  106 WNQGALEW 113
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
32-70 1.42e-14

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 63.60  E-value: 1.42e-14
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVE 70
Cdd:pfam00507  13 NPEKLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVE 51
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 32-70 1.42e-11

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 56.67  E-value: 1.42e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVE 70
Cdd:COG0838    35 NPEKLSPYECGIEPVGDARIRFSVRYYLVALLFVIFDVE 73
 
Name Accession Description Interval E-value
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 28-115 1.06e-26

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 95.23  E-value: 1.06e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  28 KTLNDHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYHE 107
Cdd:MTH00161   26 KSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFKTSNMMSWLITSSFFILILLLGLYYE 105


                  ....*...
gi 1351314702 108 WRQGALDW 115
Cdd:MTH00161  106 WNQGALEW 113
ND3 MTH00202
NADH dehydrogenase subunit 3; Provisional
 28-116 6.95e-22

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214455 [Multi-domain]  Cd Length: 117  Bit Score: 83.12  E-value: 6.95e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  28 KTLNDHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYHE 107
Cdd:MTH00202   28 RSLMDREKSSPFECGFDPKESARLPFSMRFFLLAVIFLVFDIEIALLLPLPLVLKSSWSKGGLLGGTIFLLILIGGLIHE 107


                  ....*....
gi 1351314702 108 WRQGALDWA 116
Cdd:MTH00202  108 WKEGSLDWV 116
ND3 MTH00148
NADH dehydrogenase subunit 3; Provisional
 28-116 1.00e-21

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214433 [Multi-domain]  Cd Length: 117  Bit Score: 82.60  E-value: 1.00e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  28 KTLNDHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIalllpliiiiqwskVLLWSIISSFFLIILLLGL--- 104
Cdd:MTH00148   28 RSYSDREKSSPFECGFDPISSARSPFSLRFFLLAILFLVFDVEI--------------VLLFPVLQSLGSSFSVWSLtsl 93

                          90       100
                  ....*....|....*....|...
gi 1351314702 105 -----------YHEWRQGALDWA 116
Cdd:MTH00148   94 fifllililglFHEWNEGSLDWV 116
ND3 MTH00012
NADH dehydrogenase subunit 3; Validated
 28-116 2.66e-19

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164588 [Multi-domain]  Cd Length: 117  Bit Score: 76.44  E-value: 2.66e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  28 KTLNDHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYHE 107
Cdd:MTH00012   28 RSTADREKTSPFECGFDPHKTARIPFSLRFFLLAIIFIVFDIEIVLLMPVPTILMTSTSKTVVYTSILFLLILVIGLIHE 107


                  ....*....
gi 1351314702 108 WRQGALDWA 116
Cdd:MTH00012  108 WREGSLDWS 116
ND3 MTH00136
NADH dehydrogenase subunit 3; Provisional
 32-116 4.20e-18

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177194 [Multi-domain]  Cd Length: 116  Bit Score: 73.41  E-value: 4.20e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYHEWRQG 111
Cdd:MTH00136   31 DHEKLSPYECGFDPLGSARLPFSLRFFLVAILFLLFDLEIALLLPLPWGDQLPSPLLTFFWATAVLILLTLGLIYEWLQG 110


                  ....*
gi 1351314702 112 ALDWA 116
Cdd:MTH00136  111 GLEWA 115
ND3 MTH00069
NADH dehydrogenase subunit 3; Provisional
 32-116 1.29e-17

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177141 [Multi-domain]  Cd Length: 114  Bit Score: 71.95  E-value: 1.29e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQW---SKVLLWSIIssfFLIILLLGLYHEW 108
Cdd:MTH00069   29 DSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPTPWASQLntpTNTLFWSTL---ILILLTLGLIYEW 105


                  ....*...
gi 1351314702 109 RQGALDWA 116
Cdd:MTH00069  106 IQGGLEWA 113
ND3 MTH00106
NADH dehydrogenase subunit 3; Provisional
 34-116 2.55e-17

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177168 [Multi-domain]  Cd Length: 115  Bit Score: 71.51  E-value: 2.55e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  34 EKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYHEWRQGAL 113
Cdd:MTH00106   32 EKASPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWASQTNNLNTMLTMALLLISLLALSLAYEWTQKGL 111


                  ...
gi 1351314702 114 DWA 116
Cdd:MTH00106  112 EWT 114
ND3 MTH00113
NADH dehydrogenase subunit 3; Provisional
 32-116 2.20e-16

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177175 [Multi-domain]  Cd Length: 114  Bit Score: 68.75  E-value: 2.20e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYHEWRQG 111
Cdd:MTH00113   30 DNEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAINLTTPTTTLTWATIILTLLTLGLIYEWLQG 109


                  ....*
gi 1351314702 112 ALDWA 116
Cdd:MTH00113  110 GLEWA 114
ND3 MTH00042
NADH dehydrogenase subunit 3; Validated
 32-117 1.37e-15

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 177117 [Multi-domain]  Cd Length: 116  Bit Score: 66.93  E-value: 1.37e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYHEWRQG 111
Cdd:MTH00042   31 DLEKSSPYECGFDPLNSARLPFSFRFFLVAILFLLFDLEIALLFPLPPATLITNPSTLLPISLIFLIILTIGLVYEWVNG 110


                  ....*.
gi 1351314702 112 ALDWAN 117
Cdd:MTH00042  111 GLEWAE 116
ND3 MTH00203
NADH dehydrogenase subunit 3; Provisional
 32-115 1.40e-14

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214456 [Multi-domain]  Cd Length: 112  Bit Score: 64.15  E-value: 1.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISsfFLIILLLGLYHEWRQG 111
Cdd:MTH00203   31 DGEKLSPYECGFDPLGSARLPFSLQFFLVALSFLLFDLEIALLLPLPWSNQLSSLSLLLAFL--FLILLTLGLIYEWLQG 108


                  ....
gi 1351314702 112 ALDW 115
Cdd:MTH00203  109 GLEW 112
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
32-70 1.42e-14

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 63.60  E-value: 1.42e-14
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVE 70
Cdd:pfam00507  13 NPEKLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVE 51
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 32-70 1.42e-11

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 56.67  E-value: 1.42e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVE 70
Cdd:COG0838    35 NPEKLSPYECGIEPVGDARIRFSVRYYLVALLFVIFDVE 73
ND3 MTH00055
NADH dehydrogenase subunit 3; Provisional
 32-70 3.57e-10

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177128 [Multi-domain]  Cd Length: 118  Bit Score: 53.17  E-value: 3.57e-10
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVE 70
Cdd:MTH00055   35 DSEKVSVYECGFDPFESSRIPFSVRFFLVGILFLIFDLE 73
ND3 MTH00018
NADH dehydrogenase subunit 3; Validated
 32-70 1.45e-09

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164592 [Multi-domain]  Cd Length: 113  Bit Score: 51.22  E-value: 1.45e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVE 70
Cdd:MTH00018   30 DREKVSAYECGFDPFGFPGRPFSIRFFLIGILFLIFDLE 68
PRK06602 PRK06602
NADH:ubiquinone oxidoreductase subunit A; Validated
 32-70 1.07e-08

NADH:ubiquinone oxidoreductase subunit A; Validated


Pssm-ID: 180638 [Multi-domain]  Cd Length: 121  Bit Score: 49.09  E-value: 1.07e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1351314702  32 DHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVE 70
Cdd:PRK06602   38 DREKNSPYESGFEAFGDARMKFDVRFYLVAILFVIFDLE 76
ND3 MTH00030
NADH dehydrogenase subunit 3; Provisional
 29-115 5.06e-08

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 164603 [Multi-domain]  Cd Length: 123  Bit Score: 47.62  E-value: 5.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351314702  29 TLNDHEKSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVEIALLLPLIIIIQWSKVLLWSIISSFFLIILLLGLYhEW 108
Cdd:MTH00030   37 TKPDSEKSSIYECGFDPFGKIRTPFTIKFVLVGILFMIFDIEISFLFPWSIVFNQLNLFSFWIVYTFLIVLAIGLAY-EW 115


                  ....*..
gi 1351314702 109 RQGALDW 115
Cdd:MTH00030  116 IKGGLEW 122
ND3 MTH00092
NADH dehydrogenase subunit 3; Provisional
 35-70 2.44e-03

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177155  Cd Length: 111  Bit Score: 34.87  E-value: 2.44e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1351314702  35 KSSPFECGFDPKMSPRLPFSMHFFLIAVIFLIFDVE 70
Cdd:MTH00092   34 KVSSFECGFESVGKIQNSFSIHFFKIMLMFVIFDLE 69
PRK08489 PRK08489
NAD(P)H-quinone oxidoreductase subunit 3;
35-70 2.96e-03

NAD(P)H-quinone oxidoreductase subunit 3;


Pssm-ID: 181448 [Multi-domain]  Cd Length: 129  Bit Score: 35.03  E-value: 2.96e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1351314702  35 KSSPFECGFDPKMSPRlPFSMHFFLIAVIFLIFDVE 70
Cdd:PRK08489   47 KLAIYECGPEPVKQPN-RISSHFYIMALLFILFDVE 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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